Navigation Links
Whole-genome sequencing of bulls in key beef and dairy breeds
Date:7/22/2014

An international collaboration known as the '1000 Bull Genomes Project' aims to accelerate breeding for desired traits in beef and dairy cattle while also improving animal health and welfare. Results of the project's first phase -- based on sequencing the whole genomes of 234 individual bulls whose direct descendants number in the tens of millions -- are reported in the journal Nature Genetics.

According to the researchers, breeding programs could use this information to reduce or eliminate hereditary diseases and to improve the efficency of milk and beef production.

The bulls whose genomes have been sequenced and analyzed represent four of the most commercially important cattle breeds. Scientists from the Technische Universitt Mnchen (TUM) contributed data on 43 sires of the Fleckvieh breed, which has spread to every continent from its origin in the Bavarian Alps. The estimated worldwide population of Fleckvieh dairy cows is 40 million. From the widely distributed Holstein-Friesian population, the collaborators obtained whole-genome sequences for 129 bulls with more than six million daughters on dairy farms. The Jersey breed was represented by data from 15 bulls. Previously published genome sequences for 47 Angus cattle were also integrated into the analysis.

Modern breeding practices, together with advances in genome sequencing technology and bioinformatics, have made better prediction of inherited traits not only attainable but also cost-effective on the basis of a relatively small number of individuals. Selection of sires in cattle breeding is intense, and widespread use of artificial insemination means it's not unusual for a hundred thousand animals to be descendants of a single bull. With the ancestors' sequences , breeders now have a leverage tool in hand that allows them to extrapolate the sequence information to the numerous descendants using readily available chip-based DNA microarrays.

Personal Genomics
'/>"/>

Contact: Ruedi Fries
ruedi.fries@tum.de
49-816-171-3228
Technische Universitaet Muenchen
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Whole-genome sequencing uncovers the mysteries of the endangered Chinese alligator
2. BGI Tech launches human whole exome sequencing service on complete genomics advanced platform
3. Pioneer in next generation sequencing receives 2014 HudsonAlpha Life Sciences Prize
4. Sequencing electric eel genome unlocks shocking secrets
5. Sequencing efforts miss DNA crucial to bacterias disease causing power
6. Sequencing of citrus genomes points to need for more genetic diversity to fight disease
7. Poor coverage of specific gene sets in exome sequencing gives cause for concern
8. Sequencing hundreds of nuclear genes in the sunflower family now possible
9. Research team establishes benchmark set of human genotypes for sequencing
10. CHOP introduces HLA typing by next-generation sequencing to its clinical services
11. RNA sequencing of 750-year-old barley virus sheds new light on the Crusades
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Whole-genome sequencing of bulls in key beef and dairy breeds
(Date:9/30/2014)... What do seedless watermelon, salmon, and strawberries all have ... have two sets of chromosomes and are diploid, these ... more sets of chromosomesseedless watermelon and salmon have 3 ... 10! While this might seem surprising, in fact ... was first discovered over a century ago, but only ...
(Date:9/30/2014)... Calif. The National Institutes of Health (NIH) ... today to develop an electrode array system that ... brain works through unprecedented resolution and scale. , ... to support President Obama,s BRAIN (Brain Research ... research effort to revolutionize our understanding of the ...
(Date:9/30/2014)... scientists and engineers, led by Clemson University associate ... million grant from the U.S. Department of Energy,s ... a direct positive impact on South Carolina in ... radioactive contaminants. , "Understanding the scientific and engineering ... aspects of nuclear technologies is imperative if South ...
Breaking Biology News(10 mins):Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 2Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 3Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 4NIH taps lab to develop sophisticated electrode array system to monitor brain act 2NIH taps lab to develop sophisticated electrode array system to monitor brain act 3Researchers get $5.25 million to advance nuclear technologies in South Carolina 2
... cell biologists there are few better-known proteins than nestin, whose ... "stem cell," such as a neural stem cell. As helpful ... which purpose nestin serves in a cell. In a ... of Nature Neuroscience , Salk Institute of Biological Studies ...
... of California, San Diego School of Medicine provides ... defects associated with a rare childhood neurological disease ... be defective in LND are known to be ... and Parknson,s diseases, suggesting common causes of cognitive ...
... ARBOR, Mich.---DNA, that marvelous, twisty molecule of life, has an ... University of California, Irvine reveals. On rare occasions, its ... into a different shape. "We show that the simple ... of the time---and that this alternative form is functional," said ...
Cached Biology News:Salk researchers discover that stem cell marker regulates synapse formation 2Salk researchers discover that stem cell marker regulates synapse formation 3Genetic clues to compulsive, self-injurious behavior in rare childhood disorder 2Genetic clues to compulsive, self-injurious behavior in rare childhood disorder 3DNA caught rock 'n rollin' 2
(Date:10/1/2014)... This report analyzes the worldwide markets for ... following Product Segments: Proteases, Polymerases, Carbohydrases, and ... analyzed are Pharmaceuticals & Diagnostics, Research/Biotechnology, and ... comprehensive analytics for the US, Canada, Japan, ... Annual estimates and forecasts are provided for ...
(Date:9/30/2014)... . , Electrical ... a new kind of building block for digital integrated ... be based on three-dimensional arrangements of nanometer-scale magnets instead ... semiconductor industry CMOS fabrication of silicon chips ... the University of Notre Dame are exploring "magnetic computing" ...
(Date:9/30/2014)... September 30, 2014 Shimadzu Scientific ... an easy-to-use and highly precise tool for measuring ... considerable elongation. With 1000-mm maximum movement distance, the ... for a gauge length of 10 mm. In ... accuracy above 50-mm stroke and within +/- 100 ...
(Date:9/30/2014)... San Jose, California (PRWEB) September 30, 2014 ... generally measure the level of each type of cholesterol ... essential since the presence of excessive cholesterol levels in ... is a precursor condition to heart attack and other ... of fatality worldwide, therefore testing for cholesterol levels on ...
Breaking Biology Technology:Global Specialty Enzymes Industry 2Global Specialty Enzymes Industry 3Global Specialty Enzymes Industry 4Global Specialty Enzymes Industry 5Global Specialty Enzymes Industry 6Global Specialty Enzymes Industry 7Global Specialty Enzymes Industry 8Global Specialty Enzymes Industry 9Global Specialty Enzymes Industry 10Global Specialty Enzymes Industry 11Global Specialty Enzymes Industry 12Global Specialty Enzymes Industry 13Global Specialty Enzymes Industry 14Global Specialty Enzymes Industry 15Global Specialty Enzymes Industry 16Global Specialty Enzymes Industry 17Global Specialty Enzymes Industry 18Global Specialty Enzymes Industry 19Global Specialty Enzymes Industry 20Global Specialty Enzymes Industry 21Global Specialty Enzymes Industry 22Global Specialty Enzymes Industry 23Global Specialty Enzymes Industry 24Global Specialty Enzymes Industry 25Global Specialty Enzymes Industry 26A new dimension for integrated circuits: 3-D nanomagnetic logic 2A new dimension for integrated circuits: 3-D nanomagnetic logic 3Shimadzu’s New Long-Travel Extensometer Increases Precision for Soft Material Testing 2Surging Diabetic, Obese and Hypertensive Population Drives the Global Cholesterol Testing Market, According to New Report by Global Industry Analysts, Inc. 2Surging Diabetic, Obese and Hypertensive Population Drives the Global Cholesterol Testing Market, According to New Report by Global Industry Analysts, Inc. 3Surging Diabetic, Obese and Hypertensive Population Drives the Global Cholesterol Testing Market, According to New Report by Global Industry Analysts, Inc. 4
... Corn Growers Association reminds U.S. Bt corn growers that the development of ... their planning process. , ... St. Louis, MO (PRWEB) February 20, ... Association (NCGA) reminds U.S. Bt corn growers that the development of ...
... Feb. 20 Mach One Corporation (Pink Sheets: MNCN), ... for positive, long term benefit to the agricultural and ... the acquisition of Modular Process Constructors LLC (MPC).Mach One ... $500,000 of Series B convertible preferred stock at a ...
... February 20 Authentic Natural and Organic,Cosmetic* products ... the NaTrue,Label: the first 100 products have already ... The NaTrue-Label provides orientation for ... criteria for Natural and Organic,Cosmetics. It is international, ...
Cached Biology Technology:Corn Growers Reminded to Follow Refuge Requirements as Spring Planting Nears 2Corn Growers Reminded to Follow Refuge Requirements as Spring Planting Nears 3Mach One Closes on Acquisition of Biopharmaceutical Design & Engineering Firm 2NaTrue-Label: The First 100 Products are Certified 2
...
...
... and supplies, for 10 chips, provides ... perform standard-sensitivity RNA analysis (nanogram levels) ... automated electrophoresis system. Supplied are 1,250 ... StdSens stain, 20 microliters RNA ladder, ...
... vectors are designed for enhanced translation of cloned ... rabbit reticulocyte lysate. The maps for pCITE-2b(+) and ... following exceptions: pCITE-2b(+) is a 3793 bp plasmid; ... and Xcm I sites. Subtract 7 bp from ...
Biology Products: