Navigation Links
White blood cells found to play key role in controlling red blood cell levels
Date:3/17/2013

March 17, 2013 (Bronx, NY) Researchers at Albert Einstein College of Medicine of Yeshiva University and the Icahn School of Medicine at Mount Sinai have found that macrophages white blood cells that play a key role in the immune response also help to both produce and eliminate the body's red blood cells (RBCs). The findings could lead to novel therapies for diseases or conditions in which the red blood cell production is thrown out of balance. The study, conducted in mice, is published today in the online edition of the journal Nature Medicine.

"Our findings offer intriguing new insights into how the body maintains a healthy balance of red blood cells," said study leader Paul Frenette, M.D., professor of medicine and of cell biology and director of the Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research at Einstein. "We've shown that macrophages in the bone marrow and the spleen nurture the production of new red blood cells at the same time that they clear aging red blood cells from the circulation. This understanding may ultimately help us to devise new therapies for conditions that lead to abnormal RBC counts, such as hemolytic anemia, polycythemia vera, and acute blood loss, plus aid recovery from chemotherapy and bone marrow transplantation." Einstein has filed a joint patent application with Mount Sinai related to this research, which is currently available for licensing and further commercialization.

Previous studies, all done in the laboratory, had suggested that macrophages in the bone marrow act as nurse cells
'/>"/>

Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. New research on migratory behavior of oceanic whitetip sharks can help shape conservation strategies
2. Its not just amyloid: White matter hyperintensities and Alzheimers disease
3. UGA researchers invent new material for warm-white LEDs
4. Majority of Americans doubt Congress and White House can avoid fiscal cliff
5. The smell of white
6. New ancient shark species gives insight into origin of great white
7. Whitehead scientists identify major flaw in standard approach to global gene expression analysis
8. A new technique to study how myeloids become white blood cells
9. Researchers use banker plants to help battle whitefly pests
10. Black belts white matter shows how a powerful punch comes from the brain
11. NOAA researchers see dramatic decline of endangered white abalone
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... --Research and Markets ( http://www.researchandmarkets.com/research/s6qzt5/samsung_galaxy_s5 ) ... Galaxy S5 - Home Button Synaptics Fingerprint Sensor ... http://photos.prnewswire.com/prnh/20130307/600769 ... the iPhone 5S, Samsung introduces for the first ... The Galaxy S5 home button presents an ...
(Date:12/17/2014)... Dec. 15, 2014  HITLAB SM announced ... (GCP) audit to confirm its adherence to current ... accomplishment enables HITLAB to conduct regulated smart device ... principles for patient safety and research quality. ... access, quality, and delivery with innovative technology," said ...
(Date:12/17/2014)... 16, 2014 Research and Markets ... the "Global Chemical Sensor Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 One major trend ... for medical sensors in biomedical applications. Chemical sensors ... and correct diagnosis during surgical procedures. The Global ...
Breaking Biology News(10 mins):Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2
... in those green coffee bean dietary supplements often touted ... obese laboratory mice fed a high-fat diet when given at ... in ACS, Journal of Agricultural and Food Chemistry . ... fat in the liver. Vance Matthews, Kevin Croft ...
... 2013: A new study presented today at EULAR 2013, ... shows that one in eight patients at risk of ... over-the-counter (OTC) non-steroidal anti-inflammatory drugs (NSAIDs), often to treat ... NSAID users, over one-third had taken the medication for ...
... show ways in which we can markedly improve drug targeting ... imaging techniques. In real time and in three dimensions, ... active cancer cells respond to a particular drug. They can ... to administer drugs. Finally, using preclinical models of the disease, ...
Cached Biology News:Patients use OTC NSAIDs even when they have a high risk of serious side effects 2Nanotechnology helps track and improve drug action in pancreatic cancer 2
(Date:12/22/2014)... Dec. 22, 2014   Synthetic Biologics, ... of pathogen-specific therapies for serious infections and ... microbiome, today announced positive topline safety and ... trial of SYN-004, the Company,s investigational oral ... Clostridium difficile (C. difficile) infection, antibiotic-associated ...
(Date:12/22/2014)... , Dec. 22, 2014  ( www.competitivehealth.com ) ... an online medical bill review and advocacy service, has ... the FREE WellCard Savings discount health services marketplace. ... that was more than they expected to pay. As ... health care costs, WellCard Savings is pleased to offer ...
(Date:12/19/2014)... 19, 2014 Bioject Medical Technologies ... manufacturer of needle-free injection technology, today announced that ... Therapeutics, Inc. (“ITI”) for ITI to use the ... LAMP™ vaccine platform. , In the agreement, ... license to the Biojector®-2000 that triggers based on ...
(Date:12/19/2014)...  Roche (SIX: RO, ROG; OTCQX: RHHBY) announced ... a privately held company based in ... a big data platform for centralized management and ... proprietary on-market Genomic Management Solution, Bina-GMS 1 , ... fast and scalable analyses to maximize the value ...
Breaking Biology Technology:Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 2Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 4Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 5WellCard Savings Announces CoPatient Medical Bill Review Service for Members 2Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines 2Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines 3Roche acquires Bina Technologies and enters the genomic informatics market 2Roche acquires Bina Technologies and enters the genomic informatics market 3
... LLC , a software company in Waukesha that sells home ... programs, said on Thursday it has been acquired by a ... it would expand its offerings to manufacturers and retailers by ... and product pictures. Big Hammer operates one of 11 authorized ...
... In the same week that state senators in Wisconsin ... to include ethanol, policymakers in another Midwestern state were ... , ,Agri-business giant Louis Dreyfus Corp. announced it ... northern Indiana, where it plans to crush nearly 50 ...
... company in central Wisconsin has announced its plans ... offerings of high-speed Internet and voice over IP services. ... serves about 28,000 customers. CEO Douglas Wenzlaff told reporters ... Madison and Eau Claire. Its existing base is in ...
Cached Biology Technology:Ethanol bill's death in Wisconsin ignores what's happening with our neighbors 2Ethanol bill's death in Wisconsin ignores what's happening with our neighbors 3
ABI Plant AFLP Kits • EcoRI-ACA AFLP Amplification Primers...
Lipid-rich bovine serum albumin for cell culture. It is chromatographically purified and has an IgG content 1.0% (w/w)....
Penicillin-Streptomycin liquid...
...
Biology Products: