Navigation Links
White blood cells found to play key role in controlling red blood cell levels
Date:3/17/2013

March 17, 2013 (Bronx, NY) Researchers at Albert Einstein College of Medicine of Yeshiva University and the Icahn School of Medicine at Mount Sinai have found that macrophages white blood cells that play a key role in the immune response also help to both produce and eliminate the body's red blood cells (RBCs). The findings could lead to novel therapies for diseases or conditions in which the red blood cell production is thrown out of balance. The study, conducted in mice, is published today in the online edition of the journal Nature Medicine.

"Our findings offer intriguing new insights into how the body maintains a healthy balance of red blood cells," said study leader Paul Frenette, M.D., professor of medicine and of cell biology and director of the Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research at Einstein. "We've shown that macrophages in the bone marrow and the spleen nurture the production of new red blood cells at the same time that they clear aging red blood cells from the circulation. This understanding may ultimately help us to devise new therapies for conditions that lead to abnormal RBC counts, such as hemolytic anemia, polycythemia vera, and acute blood loss, plus aid recovery from chemotherapy and bone marrow transplantation." Einstein has filed a joint patent application with Mount Sinai related to this research, which is currently available for licensing and further commercialization.

Previous studies, all done in the laboratory, had suggested that macrophages in the bone marrow act as nurse cells
'/>"/>

Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. New research on migratory behavior of oceanic whitetip sharks can help shape conservation strategies
2. Its not just amyloid: White matter hyperintensities and Alzheimers disease
3. UGA researchers invent new material for warm-white LEDs
4. Majority of Americans doubt Congress and White House can avoid fiscal cliff
5. The smell of white
6. New ancient shark species gives insight into origin of great white
7. Whitehead scientists identify major flaw in standard approach to global gene expression analysis
8. A new technique to study how myeloids become white blood cells
9. Researchers use banker plants to help battle whitefly pests
10. Black belts white matter shows how a powerful punch comes from the brain
11. NOAA researchers see dramatic decline of endangered white abalone
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 2015  A man-made form of insulin delivered by nasal ... in adults with mild cognitive impairment and Alzheimer,s disease ... at Wake Forest Baptist Medical Center. The ... cognitive impairment (MCI) or mild to moderate Alzheimer,s dementia ...
(Date:1/22/2015)... NEW YORK and POINT ROBERTS, Washington ... global news source covering leading sectors including technology and tech ... Personal Privacy marketplace featuring master pickpocket and security consultant ... wallet is stolen and talks about the Wocket™ biometric smart ...
(Date:1/22/2015)... , Europe,s most prestigious ... Office to present a video retrospective of the most exciting and ... Christofer Toumazou and Sophie Wilson   A ... Award   Starting on 22 January 2015 on   http://www.epo.org/european-inventor ...
Breaking Biology News(10 mins):Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 3Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 3Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 2Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 3
... - GEOLOGY covers multiple aspects of life on ... the first creatures to walk on land, sirenians ... the woolly mammoth, and Edwards Aquifer development as ... glaciation, mineralization, mineral decomposition, degassing, climate change, tectonics, ...
... Department,s National Institute of Standards and Technology (NIST) ... for manufacturing integrated circuits at the nanometer (billionth ... develop a method for engineering the first-ever nanoscale ... As described in a paper published online ...
... creating dispersed and chemically modified graphene sheets in a ... a University of Texas at Austin engineering team led ... graphene in a host of important materials and applications ... inks and plastic electronics. Graphene is a unique ...
Cached Biology News:April 2009 Geology and GSA Today media highlights 2April 2009 Geology and GSA Today media highlights 3April 2009 Geology and GSA Today media highlights 4April 2009 Geology and GSA Today media highlights 5April 2009 Geology and GSA Today media highlights 6April 2009 Geology and GSA Today media highlights 7April 2009 Geology and GSA Today media highlights 8April 2009 Geology and GSA Today media highlights 9April 2009 Geology and GSA Today media highlights 10April 2009 Geology and GSA Today media highlights 11NIST-Cornell team builds world's first nanofluidic device with complex 3-D surfaces 2NIST-Cornell team builds world's first nanofluidic device with complex 3-D surfaces 3NIST-Cornell team builds world's first nanofluidic device with complex 3-D surfaces 4Engineers develop method to disperse chemically modified graphene in organic solvents 2
(Date:3/4/2015)... 4, 2015 AcelRx Pharmaceuticals, Inc. (Nasdaq: ... focused on the development and commercialization of innovative ... pain, today announced that it will release fourth ... close on Monday, March 9th, 2015. AcelRx management ... p.m. Eastern Time (1:30 p.m. Pacific Time) on ...
(Date:3/4/2015)... 2015 Lancée par ... en décembre 2011, l,étude collaborative française ... qui compare   l es microsphères en ... dans le carcinome hépatocellulaire avancé, a recruté plus ... avancé   ; les résultats sont attendus fin ...
(Date:3/3/2015)... Experts and industry insiders from around ... the Alltech REBELation exploring innovation, inspiration and world-changing ideas ... its 31st year, Alltech’s annual international conference traditionally draws ... opportunity to join the REBELation at an extra discount ... EST, at which point the standard early registration rate ...
(Date:3/3/2015)... 3, 2015 Adaptive Biotechnologies announced today that ... its Board of Director as Chair of the Audit ... Group, Chad oversees all finance, treasury and accounting functions. ... core finance, treasury and accounting functions, and led the ... In 2013, he was named Puget Sound Business Journal,s ...
Breaking Biology Technology:AcelRx Pharmaceuticals to Hold Annual 2014 Financial Results Conference Call and Webcast on Monday, March 9th, 2015 2AcelRx Pharmaceuticals to Hold Annual 2014 Financial Results Conference Call and Webcast on Monday, March 9th, 2015 3Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 2Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 3Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 4Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 5Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 6World-renowned Leaders, Authors and Businesspeople Join the Alltech REBELation 2World-renowned Leaders, Authors and Businesspeople Join the Alltech REBELation 3World-renowned Leaders, Authors and Businesspeople Join the Alltech REBELation 4Adaptive Biotechnologies adds Chad Cohen, Zillow Group CFO, to Board of Directors 2
... Inc., one of the premier transplant reference and consultative ... added Chad J. Ronholdt, an innovator in the medical ... Director of Business Development.Ronholdt has led a distinguished career ... 13 years, with a solid record of transforming fundamental ...
... company that conducts original wet lab research, develops advanced bioinformatics tools, ... ... Ann Arbor, MI (PRWEB) April 29, 2009 -- DNA ... 50 Companies to Watch," an awards program sponsored by the Edward ...
... BioSciences and Arisyn Therapeutics jointly announced today that ... partnership to provide support necessary to develop Arisyn,s ... infectious disease and cancer. Arisyn has recently announced ... demonstrated preclinical efficacy against HIV, HCV, HTLV-I, influenza ...
Cached Biology Technology:Chad Ronholdt Joins LABS Inc. 2DNA Software, Inc. Honored as One of the 2009 "Michigan 50 Companies to Watch" 2DNA Software, Inc. Honored as One of the 2009 "Michigan 50 Companies to Watch" 3DNA Software, Inc. Honored as One of the 2009 "Michigan 50 Companies to Watch" 4DNA Software, Inc. Honored as One of the 2009 "Michigan 50 Companies to Watch" 5ImQuest BioSciences and Arisyn Therapeutics Announce Strategic Partnership to Develop Infectious Disease and Cancer Drugs 2
... Turner (1997). • This book describes ... the production of high-quality antibodies, the ... standardisation of antibodies and antigens, the ... enzyme immunoassays for detecting cell-surface molecules ...
... active MW: 34.2kDa Formulation: 10mM HEPES, ... 1mM dithiothreitiol with 50% glycerol Properites: ... the Certificate of Analysis for individual ... precipitation followed by gel filtration and ...
MitoScreen (JC-1) Kit , 100 tests Consult technical datasheet for details....
Thermal Printer Paper for Monolight(tm) Luminometer 1 each...
Biology Products: