Navigation Links
When our skin fails to protect us
Date:3/20/2012

The skin is the body's largest organ and an indispensable part of the immune system. As the body's outermost line of defense against microbes, the skin provides important protection against potentially toxic environmental elements. One subset of immune cells, thymus-derived T-cells play an important role in the skin's response to injury, particularly with respect to wound healing. When epidermal T-cells do not respond effectively, non-healing wounds may result. The treatment of chronic wounds is the single most important contributor to skin-related health care costs in the elderly. Professor Thomas Krieg, Dean of the Medical Faculty and Principal Investigator in the Cluster of Excellence for Cellular Stress Responses in Aging-Associated Diseases (CECAD) at the University of Cologne, Germany, will address issues and treatments of chronic wounds, which are a challenge to patients and aging societies as a whole. Prof. Krieg's research at the University of Cologne's department of dermatology includes cell-cell and cell-extracellular matrix interactions as crucial components for the maintenance of healthy skin functions.

T-cells are also involved in the development of a wide range of autoimmune disorders that affect the skin and hair. Alopecia Areata, for example, is an organ-specific autoimmune disease in which T-cells attack human hair follicles and damage them with resulting hair loss. Dr. Angela Christiano, Richard and Mildred Rhodebeck Professor of Dermatology and Professor of Genetics & Development at Columbia University Medical Center, will discuss Alopecia Areata. Her major focus of research is the study of inherited skin and hair disorders in humans, through a classical genetic approach that include identification and phenotyping of disease families, genetic linkage, gene discovery and mutation analysis, and most recently, functional studies relating these findings to basic questions in epidermal biology.

Dr. David Bickers, Carl Truman Ne
'/>"/>

Contact: Andrea Deierlein
deierlein@germaninnovation.org
212-339-8606
German Center for Research and Innovation
Source:Eurekalert

Page: 1 2

Related biology news :

1. When standard treatment fails: Jefferson to start unique immunotherapy for brain tumor patients
2. Sight fails when defective eye cells cripple renewal
3. MS study offers theory for why repair of brains wiring fails
4. Marine Protected Areas are keeping turtles safe
5. Building the European Unions Natura 2000 -- the largest ever network of protected areas
6. Improved Authentication and Confidentiality Protection. ICAP Patent Brokerage Announces for Auction Important Patents in Data Encryption and Document Security
7. Rising ocean temperatures harm protected coral reefs
8. Breakthroughs in Chikungunya research from A*STAR spell new hope for better treatment and protection
9. New study will help protect vulnerable birds from impacts of climate change
10. Protecting living fossil trees
11. Study IDs new marine protected areas in Madagascar
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/16/2014)... Respiratory Syncytial Virus causes severe respiratory tract infections ... each year. Scientists at VIB and Ghent University ... to counteract this common virus infection. , ... strategy that paves the way for the development ... a virus that causes suffering in numerous small ...
(Date:10/15/2014)... 15, 2014 Sandata Technologies, LLC, an ... community-based care, today announced it released a case ... Electronic Visit Verification™ Solution (EVV™)  for Quality Care ... health company founded in 1996 and has five ... The study details the challenges facing ...
(Date:10/15/2014)... Johannes Gutenberg University Mainz (JGU) as a full ... to maintain a significant nationwide standing in the ... of Johannes Gutenberg University Mainz as a full ... the national and international competition for the best ... can be proud that Mainz University has been ...
Breaking Biology News(10 mins):New perspectives for development of an RSV vaccine 2Sandata Announces Case Study with Quality Care Services, Inc. 2Johannes Gutenberg University Mainz joins Germany's Gauss-Allianz as a full member 2Johannes Gutenberg University Mainz joins Germany's Gauss-Allianz as a full member 3
... will soon host a round-the-clock, robotically choreographed hunt for ... leads a diverse team of scientists whose goal is ... dioxide from a power plant,s exhaust, before it leaves ... betting on a recently discovered class of materials called ...
... Scientist Jon Chase once worked in a lab that set up ... "We would try to duplicate pond communities with a given ... in each pond, and five of these species, and eight of ... grams of that and ,sproing, every replicate would do its own ...
... People often have strong opinions on the "right" firmness ... some cell types have similar preferences for their ... Institute of Standards and Technology (NIST) and the National ... offer cells a three-dimensional scaffold that varies over a ...
Cached Biology News:The search for improved carbon sponges picks up speed 2The search for improved carbon sponges picks up speed 3The great pond experiment: Regional vs. local biodiversity 2The great pond experiment: Regional vs. local biodiversity 3Scaffold gradients: Finding the right environment for developing cells 2
(Date:10/20/2014)... Convey Computer , the leader in ... State University won first place in the 2014 ... the team’s solution achieved the highest overall performance in ... place finisher. , Experts from all segments of the ... challenge, using a variety of design tools, hardware and ...
(Date:10/20/2014)... Inc. (TSXV: BRM) ("Biorem" or "the Company") today announced four new ... and provides a good start to Q4.  The orders are for ... and one in the Middle East . ... Peter Bruijns , President & CEO. "Total bidding activity and ... have been for any complete year since the company has tracked ...
(Date:10/20/2014)... Oct. 20, 2014  GenVec, Inc. (NASDAQ: GNVC ... , Ph.D., from its board of directors effective on October ... 2003, and served as its chairman from June 2006 to ... Nominating and Corporate Governance and Audit Committees of the board.  ... a decade of dedicated service to GenVec, and its stockholders," ...
(Date:10/20/2014)... 2014 OncLive® is ... Center at Thomas Jefferson University has joined its ... Strategic Alliance Partnership program, the Sidney Kimmel Cancer ... raise awareness of the Center’s cutting-edge research programs, ... Clinicians and other health care professionals from the ...
Breaking Biology Technology:Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 2Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 3Zola P. Horovitz To Retire From GenVec Board 2Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 2Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 3
... Madison, Wis. - Matt Miszewski will leave his ... at the end of February, about the time an audit ... released. , ,Miszewski, who likely will pursue opportunities in the ... e-mail and praised them for revolutionizing the use of technology ...
... Wis. - Wisconsin companies raised more venture capital in ... in both categories, according to report from Ernst & ... ,Companies in Wisconsin reported 12 venture deals in 2006, including ... a Madison-based maker of genomic research tools, for a total ...
... MailFoundry , a provider of anti-spam appliances and solutions, ... spam tactics known as botnet e-mail harvesting ... company's chief executive said the new RedListing anti-spam layer, produced ... no false positives and realtime detection capabilities. , ,David C. ...
Cached Biology Technology:Miszewski to depart as state IT audit wraps up 2Wisconsin fares slightly better in venture capital chase 2Wisconsin fares slightly better in venture capital chase 3