Navigation Links
When our skin fails to protect us
Date:3/20/2012

The skin is the body's largest organ and an indispensable part of the immune system. As the body's outermost line of defense against microbes, the skin provides important protection against potentially toxic environmental elements. One subset of immune cells, thymus-derived T-cells play an important role in the skin's response to injury, particularly with respect to wound healing. When epidermal T-cells do not respond effectively, non-healing wounds may result. The treatment of chronic wounds is the single most important contributor to skin-related health care costs in the elderly. Professor Thomas Krieg, Dean of the Medical Faculty and Principal Investigator in the Cluster of Excellence for Cellular Stress Responses in Aging-Associated Diseases (CECAD) at the University of Cologne, Germany, will address issues and treatments of chronic wounds, which are a challenge to patients and aging societies as a whole. Prof. Krieg's research at the University of Cologne's department of dermatology includes cell-cell and cell-extracellular matrix interactions as crucial components for the maintenance of healthy skin functions.

T-cells are also involved in the development of a wide range of autoimmune disorders that affect the skin and hair. Alopecia Areata, for example, is an organ-specific autoimmune disease in which T-cells attack human hair follicles and damage them with resulting hair loss. Dr. Angela Christiano, Richard and Mildred Rhodebeck Professor of Dermatology and Professor of Genetics & Development at Columbia University Medical Center, will discuss Alopecia Areata. Her major focus of research is the study of inherited skin and hair disorders in humans, through a classical genetic approach that include identification and phenotyping of disease families, genetic linkage, gene discovery and mutation analysis, and most recently, functional studies relating these findings to basic questions in epidermal biology.

Dr. David Bickers, Carl Truman Ne
'/>"/>

Contact: Andrea Deierlein
deierlein@germaninnovation.org
212-339-8606
German Center for Research and Innovation
Source:Eurekalert

Page: 1 2

Related biology news :

1. When standard treatment fails: Jefferson to start unique immunotherapy for brain tumor patients
2. Sight fails when defective eye cells cripple renewal
3. MS study offers theory for why repair of brains wiring fails
4. Marine Protected Areas are keeping turtles safe
5. Building the European Unions Natura 2000 -- the largest ever network of protected areas
6. Improved Authentication and Confidentiality Protection. ICAP Patent Brokerage Announces for Auction Important Patents in Data Encryption and Document Security
7. Rising ocean temperatures harm protected coral reefs
8. Breakthroughs in Chikungunya research from A*STAR spell new hope for better treatment and protection
9. New study will help protect vulnerable birds from impacts of climate change
10. Protecting living fossil trees
11. Study IDs new marine protected areas in Madagascar
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... French and German . ... other mammals, the difference between sexes depends on one single element ... males, where the two sexual chromosomes are X and Y, whereas ... for all the morphological and physiological differences between males and females. ... long time ago, the X and Y were identical, until the ...
(Date:4/23/2014)... their mid-thirties and forties, face a devastating prognosis: ... decades. "Mutant" protein clusters, long blamed for the ... primary focus of therapies in development by pharmaceutical ... Gerardo Lederkremer and Dr. Julia Leitman of Tel ... in collaboration with Prof. Ulrich Hartl of the ...
(Date:4/23/2014)... (Apr. 23 2014) A team of ... cells (hNSCs) into the brains of nonhuman primates ... and 24 months found that the hNSCs had ... not cause tumors. , The study will be ... Transplantation but is currently freely available on-line ...
Breaking Biology News(10 mins):Male or female? 2Male or female? 3On the defensive 2On the defensive 3Study finds long-term survival of human neural stem cells transplanted into primate brain 2
... from males can damage relationships between females is revealed in ... Centre for Research in Animal Behaviour at the University of ... B , the research uncovers the effect of sexual harassment ... with each other. The study focused on guppies, a ...
... 2009Exploring the psychology of human-nature relationships and understanding the ... at the core of the evolving discipline called ecopsychology ... journal, Ecopsychology , published by Mary Ann Liebert, ... free online at www.liebertpub.com/eco The goal ...
... has announced the university teams who won the annual ... award competition encourages college students to apply technology in ... designs must be economically profitable, which is why each ... designs. "Scientific innovation has long been a ...
Cached Biology News:Sexual harassment from males prevents female bonding, says study 2Premier issue of Ecopsychology launched by Mary Ann Liebert Inc. publishers 2Premier issue of Ecopsychology launched by Mary Ann Liebert Inc. publishers 3EPA's P3 award winners celebrate a green future 2
(Date:1/15/2014)... Two champions of science, technology, engineering, and ... annual competition for middle and high school students designed ... study. The competition presents students with real-world problems experienced ... Mathematics, and Sciences is a program administered by ...
(Date:1/15/2014)... January 15, 2014 AudioNotch is the ... therapy for the treatment of tinnitus. Patients listen to ... and over a period of weeks to months, their tinnitus ... in two forms: Notched Music and Notched White Noise. Now, ...
(Date:1/14/2014)...  3D Communications, a leading provider of strategic communications services to corporations ... in the United States and ... , JD, is returning to the firm,s Washington, D.C. ... after more than two years of service as Associate Commissioner for ...
(Date:1/14/2014)... iLab Solutions, the leader in core facility management software, ... Strategy. In this role, Michelle will work with current and ... the development of iLab products. Her main goal will be ... the scientific community by offering the most advanced, user-friendly, and ...
Breaking Biology Technology:Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Former FDA Associate Commissioner Returns To 3D Communications 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2
... -- GE Healthcare reported Monday that it ... Virginia Health System to develop new, minimally ... will use GE Healthcare's surgical navigation tools, the InstaTrak ... invasive methods of therapeutic and surgical intervention for the ...
... - Gov. Jim Doyle on Monday expressed hope ... Majority Leader Bill Frist's recent decision to support removal ... , ,Doyle made his comments at the groundbreaking of ... also praised Wisconsin's medical development scene. , ,In remarks ...
... -- Dr. Carlos Perez has been appointed to the ... Madison. Perez is a former president of the American ... years of experience in radiation oncology. , ,Perez ... at Mallinckrodt Institute of Radiology, Siteman Cancer Center, Washington ...
Cached Biology Technology:Doyle praises Frist's new stem cell research position 2Doyle praises Frist's new stem cell research position 3
Rabbit polyclonal to HMGB1 (rating: ****) ( Abpromise for all tested applications). entrezGeneID: 3146 SwissProtID: P09429...
Pooled normal sreum with 0.1% sodium azide as preservative...
Mouse CXCR3 Allophycocyanin MAb (Clone 220803)...
Mouse P-Selectin/CD62P MAb (Clone 127933)...
Biology Products: