Navigation Links
What is the brain telling us about the diagnoses of schizophrenia and bipolar disorder?
Date:9/5/2013

differ primarily by degree or are there clear categorical differences? To answer this question, researchers from a large collaborative project called BSNIP looked at a large sample of patients diagnosed with schizophrenia or bipolar disorder, their healthy relatives, and healthy people without a family history of psychiatric disorder.

They used a specialized analysis technique to evaluate the data from their multi-site study, which revealed abnormalities within seven different brain networks. Generally speaking, they found that schizophrenia and bipolar disorder showed similar disturbances in cortical circuit function. When differences emerged between these two disorders, it was usually because schizophrenia appeared to be a more severe disease. In other words, individuals with schizophrenia had abnormalities that were larger or affected more brain regions. Their healthy relatives showed subtle alterations that fell between the healthy comparison group and the patient groups.

The authors highlight the possibility that there is a continuous spectrum of circuit dysfunction, spanning from individuals without any familial association with schizophrenia or bipolar to patients carrying these diagnoses. "These findings might serve as useful biological markers of psychotic illnesses in general," said Khadka.

Krystal agreed, adding, "It is evident that neither our genomes nor our brains have read DSM-V in that there are links across disorders that we had not previously imagined. These links suggest that new ways of organizing patients will emerge once we understand both the genetics and neural circuitry of psychiatric disorders sufficiently."


'/>"/>

Contact: Jordi van de Weerd
j.weerd@elsevier.com
Elsevier
Source:Eurekalert

Page: 1 2

Related biology news :

1. Discovery helps to unlock brains speech-learning mechanism
2. Learning a new language alters brain development
3. Human brains are hardwired for empathy, friendship, study shows
4. Playing video games can boost brain power
5. How brain microcircuits integrate information from different senses
6. Making the brain take notice of faces in autism
7. Protein involved in nerve-cell migration implicated in spread of brain cancer
8. Material in dissolvable sutures could treat brain infections, reducing hospital stays
9. Practice makes the brains motor cortex more efficient, Pitt researchers say
10. MIT researchers reveal how the brain keeps eyes on the prize
11. Study reveals potential role of love hormone oxytocin in brain function
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2014)... Dec. 10, 2014  That blood pressure plays a role in ... – the medical term for high blood pressure – was ... the inflatable cuff that,s used in measuring blood pressure was ... nothing new about hypertension, its triggers and its effects. In ...
(Date:12/10/2014)... You,ve been here before: you desperately need to sign into your ... the answer to your secret question. What,s your dog,s birthday? Who ... Labs , a digital infrastructure security company, launches the ... comes with usernames, passwords and PINs – 1U TM ...
(Date:12/10/2014)...  Wake Forest Baptist Medical Center today announced plans for a ... for this $50 million capital project is part of a ... The medical education building will be located ... adjacent to 525@vine in Wake Forest Innovation Quarter. Construction will ...
Breaking Biology News(10 mins):Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4
... human mouth teems with millions of enamel-eroding, gum-inflaming microbes. ... homesteader that stakes a claim deep within the spaces ... of tooth loss ?secreting proteins that destroy the soft ... disease. , Now scientists have identified the thousands of ...
... of the world's most bio-diverse ecosystems, is at ... urban development ?problems expected to be compounded by ... Covering more than 165,000 square kilometers ?an area ... South America, the Pantanal is the world's largest ...
... a strategy involving a genetically modified baculovirus and caterpillar ... to speed up a key step in the development ... findings today at the 2005 American Society for Microbiology ... the next flu pandemic strain. It could happen at ...
Cached Biology News:UF Researchers Map Bacterial Proteins That Cause Tooth Loss 2UF Researchers Map Bacterial Proteins That Cause Tooth Loss 3South America's vast pantanal wetland may become next everglades, UNU experts warn 2South America's vast pantanal wetland may become next everglades, UNU experts warn 3South America's vast pantanal wetland may become next everglades, UNU experts warn 4South America's vast pantanal wetland may become next everglades, UNU experts warn 5South America's vast pantanal wetland may become next everglades, UNU experts warn 6Influenza vaccine uses insect cells to speed development 2
(Date:1/22/2015)... 22, 2015 The laboratory information management ... witnessed a number of technological advancements due to factors ... growing need to integrate healthcare systems, and increasing government ... in system integration. Key players in the market focus ...
(Date:1/22/2015)... 2015 zFlo Motion , a US ... an exciting product from a new partner. STT-Systems ... the past 15 years, with offerings in the optical-motion capture, ... IMU system (inertial measurement unit), iSen, is opening eyes around ...
(Date:1/22/2015)... January 22, 2015 Diagenode, Inc., ... as the Bioruptor® and complete solutions for epigenetics ... chromatin immunoprecipitation, alleviating the need for manual processing. ... needed for ChIP of histones or transcription factors ...
(Date:1/22/2015)...   GenoSpace , a precision medicine software company that has ... use of genomic, imaging and other biomedical data in research ... Munson , CEO of Aspera, an IBM Company, to its ... http://photos.prnewswire.com/prnh/20150122/170713 "We are pleased to welcome ...
Breaking Biology Technology:Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 3Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 43D Motion Capture Just Got Easy 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2GenoSpace Expands Board with Appointment of Michelle Munson 2
... May 13 Celsis International Ltd. announced today that Celsis In ... Sekisui Chemical Co. Ltd., and Sekisui Medical Co. Ltd. in a patent ... , , , ... patent owned by Celsis IVT relating to processes for producing its LiverPool™ ...
... Pa. , May 13 A guide to BRCA1 ... Inc. This comprehensive resource is designed to equip physicians and other healthcare ... help them understand the complexities of BRCA1/2 gene ... According to the ...
... , May 13 U.S. Renal Care, Inc. ("USRC"), ... it is extending its previously announced cash tender offer, through its ... of common stock of Dialysis Corporation of America (Nasdaq: DCAI ... time, on June 1, 2010 , unless further extended. ...
Cached Biology Technology:Celsis IVT Settles LiverPool Patent Infringement Suit With XenoTech, LLC 2Hayes, Inc. Releases Guide to BRCA1 and BRCA2 Genetic Testing 2U.S. Renal Care, Inc. Announces Extension of Tender Offer for Dialysis Corporation of America 2U.S. Renal Care, Inc. Announces Extension of Tender Offer for Dialysis Corporation of America 3
... Species Tissue Array (MSTA) slides were designed to ... tissues from multiple species. Tissue slices from ... slide which can then be treated as a ... in situ hybridization. This format ...
... Gene Pulser Xcell eukaryotic system, ... Hz, is used for electroporation ... includes the main unit, CE ... range) or square-wave pulses, ShockPod ...
Request Info...
... The Sub-Cell Model 96 and PowerPac basic power ... of nucleic acids in agarose gels. This Model ... x 10 cm UV-transparent gel tray with fluorescent ... power supply, 100-120 and 220-240 V, provides output ...
Biology Products: