Navigation Links
Wayne State vision restoration technology receives Notice of Allowance for US patent app
Date:3/5/2013

DETROIT Technology to restore vision through the use of a component of green algae developed by Dr. Zhou-Han Pan, professor and scientific director of the Ligon Research Center of Vision at the Kresge Eye Institute at Wayne State University, and licensed to RetroSense Therapeutics, a biotechnology company dedicated to developing gene therapy approaches to vision restoration, announced that the U.S. Patent and Trademark Office has issued a Notice of Allowance for U.S. patent application (No. 12/299,574). The notice broadly covers methods of restoring visual responses with a variety of optogenetic compounds.

The application includes claims covering methods of restoring visual responses by delivery to retinal neurons any of a number of channelrhodopsin variants, as well as halorhodopsin. The two molecules have been studied extensively and published on as means of vision restoration in retinal degenerative conditions such as retinitis pigmentosa and dry age-related macular degeneration.

The approved patent application is part of the "Pan" patent family, which stems from the novel research of Pan and others at Wayne State University and Salus University, designed to restore vision in retinal degenerative conditions. Several Pan patent applications are part of RetroSense's intellectual property estate, which focuses on optogenetic gene therapies and complementary devices for vision restoration.

"We are pleased that the U.S. Patent Office has allowed this patent application, which will substantively expand the coverage of RetroSense's intellectual property estate," said Sean Ainsworth, chief executive officer of RetroSense. "Our IP position provides broad protection. RetroSense continues to develop novel intellectual property in the area of optogenetics. Accordingly, we plan to continue to extend our basic patent protections on our technologies. We have also maintained an ongoing strategy to consolidate key intellectual property required to develop and commercialize optogenetics to restore visual responses."

The newly allowed U.S. patent application covers methods of increasing visually evoked potentials by delivering to retinal neurons one or more of the following molecules:

  • Channelrhodopsin-2 (and a multitude of variants thereof)
  • Halorhodopsin

Claims also explicitly cover targeting these molecules with cell-type specific promoters, including mGluR6 (Grm6).

Following a Notice of Allowance, the process resulting in final issuance of a patent involves several administrative steps that are typically completed within a year.


'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

Related biology news :

1. Wayne State study shows airborne dust in urban areas impacts lead levels in children
2. Wayne State University researchers techniques enable more, faster testing of biological liquids
3. Cancer risk for African-American women with benign breast disease factors Wayne State finds
4. High-strength material advancements at Wayne State University may lead to new, life-saving steel
5. New book on physics principles by Wayne State professor explains life as we know it
6. Wayne State receives $2.8 million grant from US Administration for Children and Families
7. Wayne State researchers working to improve genetic analysis, disorder detection
8. Wayne State University researchers program targets safer river fishing, anglers health
9. Celladon Corporation Receives Notice of Allowance from United States Patent and Trademark Office
10. Iowa State computer, electrical engineers working to help biologists cope with big data
11. Thomas Jefferson University researchers discover new pathways that drive metastatic prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/4/2017)... , April 4, 2017   EyeLock LLC , ... that the United States Patent and Trademark Office (USPTO) ... covers the linking of an iris image with a ... and represents the company,s 45 th issued patent. ... is very timely given the multi-modal biometric capabilities that ...
(Date:3/30/2017)... The research team of The Hong Kong Polytechnic University ... adopting ground breaking 3D fingerprint minutiae recovery and matching technology, pushing ... for use in identification, crime investigation, immigration control, security of access ... ... A research team led by Dr Ajay ...
(Date:3/28/2017)... March 28, 2017 The report ... (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, VMS), ... - Global Forecast to 2022", published by MarketsandMarkets, the ... and is projected to reach USD 75.64 Billion by ... 2022. The base year considered for the study is ...
Breaking Biology News(10 mins):
(Date:9/19/2017)... ... September 19, 2017 , ... ... Financial Services (NYS DFS) cybersecurity regulations have transitioned into full force ... organizations operating in the state (“Covered Entities”) to conduct an annual, professional, ...
(Date:9/18/2017)... ... September 18, 2017 , ... ... to produce biochar, briquettes, and torrefied wood is the topic of a ... To characterize the potential economic viability of transportable biomass conversion facilities for producing ...
(Date:9/18/2017)... , Sept. 18, 2017   Montrium , a growing leader ... exciting new partnership with a groundbreaking non-profit research organization, Multidisciplinary ... ... psychotherapy studies for PTSD ... recently granted Breakthrough Therapy Designation to MDMA for the treatment of ...
(Date:9/17/2017)... ... September 17, 2017 , ... GeneOne Life ... of Food and Drug Safety (KMFDS) for an Investigational New Drug application for ... Respiratory Syndrome coronavirus (MERS-CoV). The study in Korea represents the second clinical trial ...
Breaking Biology Technology: