Navigation Links
Wayne State vision restoration technology receives Notice of Allowance for US patent app
Date:3/5/2013

DETROIT Technology to restore vision through the use of a component of green algae developed by Dr. Zhou-Han Pan, professor and scientific director of the Ligon Research Center of Vision at the Kresge Eye Institute at Wayne State University, and licensed to RetroSense Therapeutics, a biotechnology company dedicated to developing gene therapy approaches to vision restoration, announced that the U.S. Patent and Trademark Office has issued a Notice of Allowance for U.S. patent application (No. 12/299,574). The notice broadly covers methods of restoring visual responses with a variety of optogenetic compounds.

The application includes claims covering methods of restoring visual responses by delivery to retinal neurons any of a number of channelrhodopsin variants, as well as halorhodopsin. The two molecules have been studied extensively and published on as means of vision restoration in retinal degenerative conditions such as retinitis pigmentosa and dry age-related macular degeneration.

The approved patent application is part of the "Pan" patent family, which stems from the novel research of Pan and others at Wayne State University and Salus University, designed to restore vision in retinal degenerative conditions. Several Pan patent applications are part of RetroSense's intellectual property estate, which focuses on optogenetic gene therapies and complementary devices for vision restoration.

"We are pleased that the U.S. Patent Office has allowed this patent application, which will substantively expand the coverage of RetroSense's intellectual property estate," said Sean Ainsworth, chief executive officer of RetroSense. "Our IP position provides broad protection. RetroSense continues to develop novel intellectual property in the area of optogenetics. Accordingly, we plan to continue to extend our basic patent protections on our technologies. We have also maintained an ongoing strategy to consolidate key intellectual property required to develop and commercialize optogenetics to restore visual responses."

The newly allowed U.S. patent application covers methods of increasing visually evoked potentials by delivering to retinal neurons one or more of the following molecules:

  • Channelrhodopsin-2 (and a multitude of variants thereof)
  • Halorhodopsin

Claims also explicitly cover targeting these molecules with cell-type specific promoters, including mGluR6 (Grm6).

Following a Notice of Allowance, the process resulting in final issuance of a patent involves several administrative steps that are typically completed within a year.


'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

Related biology news :

1. Wayne State study shows airborne dust in urban areas impacts lead levels in children
2. Wayne State University researchers techniques enable more, faster testing of biological liquids
3. Cancer risk for African-American women with benign breast disease factors Wayne State finds
4. High-strength material advancements at Wayne State University may lead to new, life-saving steel
5. New book on physics principles by Wayne State professor explains life as we know it
6. Wayne State receives $2.8 million grant from US Administration for Children and Families
7. Wayne State researchers working to improve genetic analysis, disorder detection
8. Wayne State University researchers program targets safer river fishing, anglers health
9. Celladon Corporation Receives Notice of Allowance from United States Patent and Trademark Office
10. Iowa State computer, electrical engineers working to help biologists cope with big data
11. Thomas Jefferson University researchers discover new pathways that drive metastatic prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2017)... , May 16, 2017   Bridge Patient ... organizations, and MD EMR Systems , an ... partner for GE, have established a partnership to ... product and the GE Centricity™ products, including Centricity ... These new integrations will allow ...
(Date:4/19/2017)... April 19, 2017 The global ... landscape is marked by the presence of several large ... held by five major players - 3M Cogent, NEC ... accounted for nearly 61% of the global military biometric ... in the global military biometrics market boast global presence, ...
(Date:4/13/2017)... 13, 2017 UBM,s Advanced Design and Manufacturing ... feature emerging and evolving technology through its 3D Printing ... run alongside the expo portion of the event and ... demonstrations focused on trending topics within 3D printing and ... manufacturing event will take place June 13-15, 2017 at the ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... Canada (PRWEB) , ... May 23, 2017 , ... ... Firmex FileSend, a cloud-based file transfer solution that makes it easy for organizations ... without having to worry about cumbersome FTP software or email file size limitations. ...
(Date:5/23/2017)... ... May 22, 2017 , ... NetDimensions has been ranked ... Research Globe™ for Corporate Learning, 2017. , Aragon Research defines Leaders as organizations ... effectively perform against those strategies. NetDimensions’ ranking as a Leader due to its ...
(Date:5/23/2017)... ... May 23, 2017 , ... Kathy Goin is ... Clinical Operations. She brings years of expertise in establishing and leading clinical operations ... as a licensed occupational therapist, through a variety of leadership roles in Clinical ...
(Date:5/22/2017)... ... May 22, 2017 , ... Stratevi, a boutique firm that partners ... Coast. It has opened an office in downtown Boston at 745 Atlantic Ave. ... more important to generate evidence on the value they provide, not just to patients, ...
Breaking Biology Technology: