Navigation Links
Wayne State researchers working to improve genetic analysis, disorder detection
Date:8/3/2012

DETROIT Wayne State University researchers are testing a way to determine the status of fetal chromosomes that could lead to healthier outcomes for mothers and their babies.

Supported by a two-year, $418,000 exploratory/developmental grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health, the researchers will capture human fetal cells for genetic study within the first two months of pregnancy using a newly developed, safe, noninvasive retrieval technique similar to a Pap test.

D. Randall Armant, Ph.D., and Michael P. Diamond, M.D., professors of obstetrics and gynecology in Wayne State's School of Medicine, are the principal investigators of the study. Susan Land, Ph.D., associate professor of obstetrics and gynecology, is a co-investigator.

Titled "Genetic Analysis of Human First Trimester Trophoblast in Ongoing Pregnancies," the project targets cells called trophoblasts, which surround the blastocyst, a cluster of cells that results from successful fertilization. Researchers are particularly interested in "invasive" trophoblasts, which attach the blastocyst to the uterine wall; the cells become the placenta and the membranes that nourish and protect the developing organism.

Such cells carry genetic material from the fetus. Armant's team will gather them through transcervical sampling, a method that uses a cytobrush inserted into the cervix. Researchers believe the technique is less intrusive than previously used methods, yields intact fetal cells and can be done as early as six to 12 weeks; doctors typically must wait 10 to 14 weeks to use other methods, which can carry more risk to mothers and fetuses.

"The earlier you get the information, the more time the doctor has to manage whatever problems are coming up during or after the mother's pregnancy," Armant said. "It also gives the parents more time to make decisions about the pregnancy.
'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

Page: 1 2

Related biology news :

1. Wayne State University researchers program targets safer river fishing, anglers health
2. Marshall University study may lead to new treatments for prostate cancer
3. Interventional radiology: Potential breakthrough to treat mens enlarged prostate
4. Carnegies Greg Asner named Energy/Climate Fellow by US State Department
5. Planet under Pressure conference, London: Final statement
6. Tokai Pharmaceuticals galeterone well-tolerated in patients with advanced prostate cancer
7. NRC authors brief federal agencies on the state of polar regions
8. Study shows botanical formula fights prostate cancer
9. Ohio state hosts national energy conference
10. New diagnostic tool determines aggressiveness of prostate cancer
11. Syracuse University study finds autumn advantage for invasive plants in eastern United States
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/6/2014)... -- A groundbreaking paper from a team of Florida ... of how plants could adapt to and survive environmental ... published in the latest issue of the journal ... (the complex of DNA and proteins) is organized in ... that some genes are turned on and others are ...
(Date:11/6/2014)... - Insilico Medicine, Inc, a Baltimore-based bioinformatics company ... diseases announced a research collaboration with the international ... Inc (OTC: CSBR). , "There are many companies ... Champions Oncology,s TumorGraft technology is unique in a ... experimentally generating vast amounts of valuable data. Our ...
(Date:11/5/2014)... Janeiro, Brazil -Individuals show great diversity in their ability ... and females greatly differ in their perceptual evaluation of ... smell tests. , Sex differences in olfactory ... and may be connected to one,s perception of smell, ... Thus, women,s olfactory superiority has been suggested to be ...
Breaking Biology News(10 mins):Maize analysis yields whole new world of genetic science 2Insilico Medicine, Inc announces research collaboration with Champions Oncology, Inc 2The female nose always knows: Do women have more olfactory neurons? 2
... University of Missouri leaders celebrated a nanomedicine milestone today ... development company. The new company forms a partnership between ... testing of a potential cancer treatment created at MU. ... suppliers of ibuprofen, formed the new company in partnership ...
... feed itself. And it can make the transition ... The startling assertions, in stark contrast with entrenched, ... studies published today that present a clear prescription for ... economy. The strategy calls on governments to make ...
... Cincinnati, OH, December 2, 2010 -- Managing diabetes in ... exercise. Buying essential medical supplies, such as needles and ... to a new study soon to be published in ... arises from the financial burden of diabetes management increases a ...
Cached Biology News:MU cancer scientists form new company with international pharmaceutical firm 2MU cancer scientists form new company with international pharmaceutical firm 3Africa can feed itself in a generation: Study 2Africa can feed itself in a generation: Study 3Africa can feed itself in a generation: Study 4Africa can feed itself in a generation: Study 5Africa can feed itself in a generation: Study 6Africa can feed itself in a generation: Study 7New study calls for greater awareness of food supply for children with diabetes 2
(Date:11/22/2014)... MI (PRWEB) November 22, 2014 ... to simulate the proper management of life-like respiratory ... test lung devices . Grand Rapids-based, Michigan Instruments ... to donate two of the respiratory simulation units ... $15,000 each. Grand Valley and Muskegon Community College ...
(Date:11/21/2014)... 2014 The science of light and ... with more than 200 primary students in a traveling ... University of Otago Physics Department and funded by an ... members of the university’s OSA/SPIE Student Chapter visited six ... giving children from small, rural schools hands-on lessons in ...
(Date:11/21/2014)... The November 2014 issue of BioTechniques ... access journal featuring the following articles:, , ... photoresponsiveness in the retina , DNA from ... using chromogenic substrates in zebrafish , Re-use ... electrophoresis , Nuclear LC3-positive puncta in stressed ...
(Date:11/21/2014)... Nov. 20, 2014 Polaris Group announced ... in its Phase 1 trial of ADI-PEG 20 ... treatment of malignant pleural mesothelioma (MPM) and non-squamous ... clinical trials on ADI-PEG 20, both as monotherapy ... treatment of several other indications, including breast cancer, ...
Breaking Biology Technology:Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 2Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 3Optics and photonics outreach programs share science, spark fascination with light 2Optics and photonics outreach programs share science, spark fascination with light 3BioTechniques: The International Journal of Life Science Methods Announces the Publication of the November 2014 Issue—Available in Print and Online 2BioTechniques: The International Journal of Life Science Methods Announces the Publication of the November 2014 Issue—Available in Print and Online 3Polaris Group Announces Treatment of First Patient in Phase 1 Study of ADI-PEG 20 plus Pemetrexed and Cisplatin in Malignant Pleural Mesothelioma And Non-Squamous Non-Small Cell Lung Carcinoma 2
... that helps solve the structure of graphite oxide and ... thick substance called graphene, which has applications in nanoelectronics, ... and cars has been created by researchers at The ... idea of the nanomaterial graphene, imagine a lightweight material ...
... Sept. 25 /PRNewswire-FirstCall/ - Dragon Pharmaceutical Inc.,("Dragon Pharma" ... DRP), a,leading international pharmaceutical company, today announced that ... Wong, Chief Financial,Officer will present at 9:30 a.m. ... 2008 at the Chateau Frontenac hotel in Quebec ...
... Expects Revenue of $88 to $90 Million and Net Income of $27 ... ... China, Sept. 25 /Xinhua-PRNewswire-FirstCall/ -- China Sky One,Medical, Inc. ("China Sky One ... company producing over-the-counter,drugs in the People,s Republic of China ("PRC"), today announced ...
Cached Biology Technology:New graphene-based material clarifies graphite oxide chemistry 2New graphene-based material clarifies graphite oxide chemistry 3China Sky One Medical, Inc. Raises Guidance for 2008 Revenue and Net Income 2China Sky One Medical, Inc. Raises Guidance for 2008 Revenue and Net Income 3
Protein 3D structure prediction, via threading. Easy to use....
DITHIOTHREITOL, 150UMOL, 1 EA. Dithiothreitol (DTT), 0.1 M Solution:, *0.1 M solution of DTT in high purity dH2O., *0.2 m filtered., *Storage: -20C. Category: SEQUENASE....
75 x 25 mm; sterile, recommended for immunohistochemistry of cell lines growing in suspension, Poly-D-Lysine coated, glass slides with polystyrene vessel, lid and safety removal tool...
IMAGEQUANT 300 WKSTN, 1 EA. Category: ImageQuant CCD Imagers....
Biology Products: