Navigation Links
Wayne State University researcher's techniques enable more, faster testing of biological liquids
Date:2/21/2013

DETROIT Two National Science Foundation (NSF) grants to a Wayne State University researcher could amount to far more than a drop in the bucket when it comes to handling liquids for biological screening.

Amar Basu, Ph.D., assistant professor of electrical and computer engineering and biomedical engineering in the College of Engineering, recently received the grants, which total $636,000, to support his work on microfluidic technologies in an effort to help scientists rapidly conduct thousands of chemical, genetic and pharmacological tests through a process called high-throughput screening (HTS).

The process is used to identify active compounds, antibodies or genes that modulate biomolecular pathways and can provide the information necessary to design drugs and understand individual biochemical processes. HTS is usually cost-prohibitive because it relies on sophisticated liquid handling robotics, sensitive detectors and, last but not least, the significant recurring cost of expensive biochemical reagents.

Since joining Wayne State in 2008, Basu has been developing techniques for performing biological analysis in microdroplets with nanoliter-picoliter volumes 1,000 to 1 million times smaller than conventional technology.

Analyzing small volumes of a substance, or assays, is a growing trend in the modern biotechnology industry because it dramatically reduces the costs of HTS reagents, improves assay speed and enables new capabilities, such as the ability to culture single cells and control their microenvironment.

"Droplet microreactors have a clear economic benefit in high-throughput biology because the smaller your assay volume, the cheaper it's going to be," Basu said. "From a scientific standpoint, microreactors can give us exciting new ways to study biology at really small size scales, comparable to individual cells.

"One of the challenges, though, is how we physically handle these tiny droplets, and mon
'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Wayne State University researchers program targets safer river fishing, anglers health
2. Wayne State researchers working to improve genetic analysis, disorder detection
3. Wayne State receives $2.8 million grant from US Administration for Children and Families
4. New book on physics principles by Wayne State professor explains life as we know it
5. High-strength material advancements at Wayne State University may lead to new, life-saving steel
6. Cancer risk for African-American women with benign breast disease factors Wayne State finds
7. Marshall University study may lead to new treatments for prostate cancer
8. Interventional radiology: Potential breakthrough to treat mens enlarged prostate
9. Carnegies Greg Asner named Energy/Climate Fellow by US State Department
10. Planet under Pressure conference, London: Final statement
11. Tokai Pharmaceuticals galeterone well-tolerated in patients with advanced prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Wayne State University researcher's techniques enable more, faster testing of biological liquids
(Date:4/17/2014)... hundred births, Down syndrome - or trisomy 21 - ... It results from a chromosomal abnormality where cells of ... (1% of the human genome). A study conducted by ... Genetic Medicine and Development at the University of Geneva ... shed light on how the extra chromosome 21 upsets ...
(Date:4/17/2014)... Clemson professor Rajendra Singh Thursday as a "Champion ... expand solar deployment in the residential, commercial and ... Professor of Electrical and Computer Engineering and director ... a local hero leading the charge across the ... solar power and driving policy changes at the ...
(Date:4/17/2014)... such as heart disease, epilepsy and pain, making them ... is still much scientists do not know about the ... into the structure of sodium channels and, specifically, one ... responsible for ,fine-tuning, the activity of the channel. The ... the Journal of Biological Chemistry . , Nerves ...
Breaking Biology News(10 mins):Trisomy 21: How an extra little chromosome throws the entire genome off balance 2Trisomy 21: How an extra little chromosome throws the entire genome off balance 3White House honors Clemson professor as 'Champion of Change' for solar deployment 2Structure of sodium channels different than previously believed 2
... AWRE ), a leading supplier of broadband technology and biometrics ... 30, 2010.   Revenues for the third quarter of ... million in the same quarter last year. Net income for the ... These results compared to a net loss of $1.1 million, or ...
... BOSTON The discovery that a protein called Rictor plays ... AKT oncogene could provide scientists with a new molecular target ... September 2010 issue of the journal Molecular Cell , ... Medical Center (BIDMC). The oncogenic cousin, known as ...
... Nanomedicine Center for Nucleoprotein Machines has received an award ... its renewal by the National Institutes of Health (NIH). ... of a clinically viable gene correction technology for single-gene ... disease. Sickle cell disease is a genetic condition ...
Cached Biology News:Aware, Inc. Reports Third Quarter 2010 Financial Results 2Aware, Inc. Reports Third Quarter 2010 Financial Results 3Aware, Inc. Reports Third Quarter 2010 Financial Results 4Aware, Inc. Reports Third Quarter 2010 Financial Results 5Rictor protein offers scientists a new molecular target for cancer therapies 2NIH renews Nanomedicine Center focused on treating single-gene disorders for $16.1 million 2NIH renews Nanomedicine Center focused on treating single-gene disorders for $16.1 million 3NIH renews Nanomedicine Center focused on treating single-gene disorders for $16.1 million 4
(Date:1/14/2014)... EquitiesIQ, a leading informational research provider, has ... an emerging biomedical company acquiring, developing, manufacturing, and marketing ... Free report download: http://equitiesiq.com/reports/alliqua/ , In late ... and Board, which launched the company’s new strategy to ...
(Date:1/14/2014)... iLab Solutions, the leader in core facility ... of Product Strategy. In this role, Michelle will work with ... guide in the development of iLab products. Her main goal ... benefit to the scientific community by offering the most advanced, ...
(Date:1/14/2014)... January 14, 2014 Global Record ... innovative information technology solutions for patients, physicians, the ... stakeholders, announced today the signing of a three-year ... and Drug Administration (FDA). This initiative is ...
(Date:1/14/2014)... January 14, 2014 Kerr Corporation, a leading ... and additional how-to information about dual arch impressions on its ... Dual Arch Impressions,” the blog entry serves up a list ... houses a step-by-step demonstration by Dr. David Little as he ...
Breaking Biology Technology:EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2
... 2011 GeoVax Labs, Inc. (OTCQB/OTCBB: GOVX), ... HIV/AIDS vaccines, announced today the opening of a third ... vaccine.  The Los Angeles-based AIDS Research Alliance (ARA) will ... site team: the AIDS Research Consortium of Atlanta and ...
... to detect the levels of vitamin B12 using your breath, ... help to avoid the potentially fatal symptoms of B12 deficiency. ... in IOP Publishing,s Journal of Breath Research , researchers ... accurately measure vitamin B12. Vitamin B12 deficiency is ...
... 2011 Veredus Laboratories, a leading provider of molecular ... STM ), today announced the successful development and ... to detect 10 to 12 food-borne pathogens in one ... (E. coli) responsible for the recent severe food poisoning ...
Cached Biology Technology:GeoVax Initiates Third Site For Therapeutic Testing of Its HIV Vaccine 2GeoVax Initiates Third Site For Therapeutic Testing of Its HIV Vaccine 3GeoVax Initiates Third Site For Therapeutic Testing of Its HIV Vaccine 4A breath of fresh air for detecting vitamin B12 deficiency 2Veredus Laboratories Develops Lab-on-Chip Solution to Detect and Differentiate Several Food-Borne Pathogens, Including Escherichia coli (E. coli) 2Veredus Laboratories Develops Lab-on-Chip Solution to Detect and Differentiate Several Food-Borne Pathogens, Including Escherichia coli (E. coli) 3Veredus Laboratories Develops Lab-on-Chip Solution to Detect and Differentiate Several Food-Borne Pathogens, Including Escherichia coli (E. coli) 4
... A direct, simple approach to ... well surface of an EIA ... maintains its integrity and availability ... dry, room temperature conditions ...
AC input: 230 V...
... lyophilization stabilizer is designed to stabilize ... for long-term storage. There are ... It is a convenient 10 ... and is superior to other traditional ...
... Freedom EVO Clinical is Tecans open platform ... enhance quality, safety and performance in the ... is provided by flexible barcode reading and ... mention that the system complies with the ...
Biology Products: