Navigation Links
Wayne State University researcher's techniques enable more, faster testing of biological liquids
Date:2/21/2013

DETROIT Two National Science Foundation (NSF) grants to a Wayne State University researcher could amount to far more than a drop in the bucket when it comes to handling liquids for biological screening.

Amar Basu, Ph.D., assistant professor of electrical and computer engineering and biomedical engineering in the College of Engineering, recently received the grants, which total $636,000, to support his work on microfluidic technologies in an effort to help scientists rapidly conduct thousands of chemical, genetic and pharmacological tests through a process called high-throughput screening (HTS).

The process is used to identify active compounds, antibodies or genes that modulate biomolecular pathways and can provide the information necessary to design drugs and understand individual biochemical processes. HTS is usually cost-prohibitive because it relies on sophisticated liquid handling robotics, sensitive detectors and, last but not least, the significant recurring cost of expensive biochemical reagents.

Since joining Wayne State in 2008, Basu has been developing techniques for performing biological analysis in microdroplets with nanoliter-picoliter volumes 1,000 to 1 million times smaller than conventional technology.

Analyzing small volumes of a substance, or assays, is a growing trend in the modern biotechnology industry because it dramatically reduces the costs of HTS reagents, improves assay speed and enables new capabilities, such as the ability to culture single cells and control their microenvironment.

"Droplet microreactors have a clear economic benefit in high-throughput biology because the smaller your assay volume, the cheaper it's going to be," Basu said. "From a scientific standpoint, microreactors can give us exciting new ways to study biology at really small size scales, comparable to individual cells.

"One of the challenges, though, is how we physically handle these tiny droplets, and mon
'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Wayne State University researchers program targets safer river fishing, anglers health
2. Wayne State researchers working to improve genetic analysis, disorder detection
3. Wayne State receives $2.8 million grant from US Administration for Children and Families
4. New book on physics principles by Wayne State professor explains life as we know it
5. High-strength material advancements at Wayne State University may lead to new, life-saving steel
6. Cancer risk for African-American women with benign breast disease factors Wayne State finds
7. Marshall University study may lead to new treatments for prostate cancer
8. Interventional radiology: Potential breakthrough to treat mens enlarged prostate
9. Carnegies Greg Asner named Energy/Climate Fellow by US State Department
10. Planet under Pressure conference, London: Final statement
11. Tokai Pharmaceuticals galeterone well-tolerated in patients with advanced prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Wayne State University researcher's techniques enable more, faster testing of biological liquids
(Date:7/28/2014)... Reactions among minerals and organic compounds in hydrothermal environments ... they provide energy for the deep biosphere, and may ... little is known about how minerals influence organic reactions. ... have demonstrated how a common mineral acts as a ... need for toxic solvents or expensive reagents. , At ...
(Date:7/28/2014)... 10 U.S. cities that have seen an increase in ... road closures, overwhelmed storm drains and compromised infrastructure--are on ... report. , This nuisance flooding, caused by rising sea ... 300 and 925 percent since the 1960s. , The ... around the United States, also finds Annapolis and Baltimore, ...
(Date:7/28/2014)... study found that 73 percent of adult survivors of ... metabolic syndrome and related health problems by failing to ... current issue of the journal Cancer . , ... childhood cancer in the study had metabolic syndrome, an ... pressure, abdominal obesity, elevated triglyceride and other abnormalities that ...
Breaking Biology News(10 mins):Mineral magic? Common mineral capable of making and breaking bonds 2Mineral magic? Common mineral capable of making and breaking bonds 3NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 2NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 3Unhealthy habits more than double risk of metabolic syndrome in childhood cancer survivors 2Unhealthy habits more than double risk of metabolic syndrome in childhood cancer survivors 3
... Md., Sept. 19, 2012  BioFortis Inc., a leading ... research space, today introduced its Next Generation ... It will help pharmaceutical, government and academic ... translational studies to safely and effectively conduct ...
... Va.Dr. John P. Holdren, White House Office of Science ... roster of military and government leaders at the Office ... and ASNE Expo, officials announced Sept. 18. Holdren, ... and co-chair of the President,s Council of Advisors on ...
... residents with disabilities, along with their families, can look ... Developmental Disabilities Institute (DDI) at Wayne State University. ... from the U.S. Administration for Children and Families. ... contributing to the development of inclusive communities and quality ...
Cached Biology News:BioFortis Inc., Introduces Next Generation Biobanking Software Platform for Biomarker-Based Clinical Research 2ONR lines up speakers and technologies for 2012 Naval Conference 2Wayne State receives $2.8 million grant from US Administration for Children and Families 2Wayne State receives $2.8 million grant from US Administration for Children and Families 3
(Date:7/29/2014)... The first product launch from start-up Hurley Research ... What sets Droidles completely apart from other stand alone ... to communicate, share code with each other and evolve ... invention is the system,” said Hurley Research founder Jay ... their own, both physically and on the internet." Remote ...
(Date:7/29/2014)... The prestigious "Discovery or Exploration in ... awarded to Juliana Hillis and Kaylie O’Connell, students at ... “From an Egg, Everything: America’s First IVF Baby". This ... the National History Day program during a week-long final ... in Washington, D.C. , The growing popularity of the ...
(Date:7/29/2014)... CA (PRWEB) July 29, 2014 ... medical devices, and cloud based eClinical technologies, have been ... Device Online. These follow a long line of white ... profile publications including Life Science Leader, Pharmaceutical Online, and ... Clinovo provided a paper by CTO Marc Desgrousilliers, ...
(Date:7/29/2014)... , July 29, 2014 ... System (LBS) zur Erfassung biologischer Daten in ... entwickelt und patentiert. Das LBS nimmt gleichzeitig ... Koronararterie des Patienten und sucht erhöhte biologische ... das Potenzial, die Entdeckung und Entwicklung neuer ...
Breaking Biology Technology:Droidles, the Social Network of Robots and Open Source Platform for the Internet of Things, Launches for Crowd Funding on IndieGoGo.com 2In Vitro Fertilization (IVF) was the Subject of This Year’s Winning Entry for the Prestigious Library of Congress “Discovery or Exploration in History Award” 2In Vitro Fertilization (IVF) was the Subject of This Year’s Winning Entry for the Prestigious Library of Congress “Discovery or Exploration in History Award” 3Clinovo White Papers Published in Summer 2014 Editions of Leading Medical Device & Pharmaceutical Publications 2Clinovo White Papers Published in Summer 2014 Editions of Leading Medical Device & Pharmaceutical Publications 3PlaqueTec sichert sich CE-Kennzeichnung für Liquid Biopsy System - bahnbrechende Innovation zur Erfassung neuer biologischer Informationen aus erkranktem Herzkranzgefäß 2PlaqueTec sichert sich CE-Kennzeichnung für Liquid Biopsy System - bahnbrechende Innovation zur Erfassung neuer biologischer Informationen aus erkranktem Herzkranzgefäß 3PlaqueTec sichert sich CE-Kennzeichnung für Liquid Biopsy System - bahnbrechende Innovation zur Erfassung neuer biologischer Informationen aus erkranktem Herzkranzgefäß 4
... Prepare for Zingo Launch ... Promoted To Senior Vice President, Marketing and Sales, and ... - Additional Manufacturing Capacity in China -, - Details to be Presented at Investor Briefing Today at ... Time -, ...
... TPPII may contribute to obesity by stimulating the formation of ... The enzyme, TPPII, has previously been linked to making people ... it may be even more deeply involved in causing obesity. ... of fat cells in worms and mammalian cells and that ...
... Ill. New sol-gel inks developed by researchers at ... to produce three-dimensional structures of metal oxides with nanoscale ... at the nanoscale opens a new avenue to functional ... gas sensors., The researchers describe the new inks in ...
Cached Biology Technology:Anesiva Outlines Comprehensive Commercialization Plan for FDA Approved Product Zingo(TM) 2Anesiva Outlines Comprehensive Commercialization Plan for FDA Approved Product Zingo(TM) 3Anesiva Outlines Comprehensive Commercialization Plan for FDA Approved Product Zingo(TM) 4Anesiva Outlines Comprehensive Commercialization Plan for FDA Approved Product Zingo(TM) 5Anesiva Outlines Comprehensive Commercialization Plan for FDA Approved Product Zingo(TM) 6Anesiva Outlines Comprehensive Commercialization Plan for FDA Approved Product Zingo(TM) 7Sol-gel inks produce complex shapes with nanoscale features 2
... Our Accumix standard is a new tuning ... electrospray ionization mass spectrometry. Accumix is ... mass range coverage for both tuning and ... and LTQ-MS) and Fourier transform mass spectrometers. ...
Determine relative degree of protein binding to phosphoinositides...
... Pipette is a synonym for pipetting accuracy, ... design, and superior operating comfort. Its single, ... measuring stroke and blow-out as well as ... ensures utmost accuracy and precision. Ejection sleeve ...
Goat polyclonal to STMN2 ( Abpromise for all tested applications). Antigen: Synthetic peptide: AKTAMAYKEK, corresponding to C terminal amino acids 2-11 of STMN2. Entrez Gene ID: 11075 Swi...
Biology Products: