Navigation Links
Vitamin K does not stem BMD decline in postmenopausal women with osteopenia
Date:10/13/2008

In a randomized controlled trial called the "Evaluate the Clinical use of vitamin K Supplementation in Postmenopausal Women with Osteopenia" (ECKO) trial, Angela Cheung and colleagues at the University of Toronto found that a high dose daily vitamin K1 supplement did not protect against age-related bone mineral density (BMD) decline. However, as reported in this week's PLoS Medicine, the findings also suggest that vitamin K1 may protect against fracture and cancer in postmenopausal women with osteopenia.

Dr. Cheung and colleagues randomized 440 postmenopausal women with osteopenia to receive either 5 mg of vitamin K1 or a placebo daily for two years. Two hundred and sixty one of these women continued their treatment for two more years to gather information about the long-term effects of vitamin K1 supplementation.

After two years and after four years, lower back and hip measurements of bone mineral density (BMD) had decreased by similar amounts in both the vitamin K and the placebo groups.

Over the four-year period, fewer women in the vitamin K group had fractures (9 versus 20 women in the placebo group) and fewer women had cancer (3 versus 12). Vitamin K supplementation was well tolerated over the four-year period and adverse health effects were similar in the two treatment groups, report the researchers. They emphasize that the study was not powered to examine fractures or cancers and the numbers were small, therefore the findings must be interpreted with caution.

The researchers say that larger studies are needed to examine the effect of vitamin K1 on fractures and on cancer and, until these are done, high dose vitamin K1 supplementation should not be recommended for the prevention of osteoporosis.

In the US, 10 million people have osteoporosis and 18 million have osteopenia, a milder condition that precedes osteoporosis.


'/>"/>

Contact: Andrew Hyde
press@plos.org
44-122-346-3330
Public Library of Science
Source:Eurekalert

Page: 1

Related biology news :

1. Lack of vitamin D linked to Parkinsons disease
2. Vitamin D a key player in overall health of several body organs, says UC Riverside biochemist
3. Vitamin C supplements may reduce benefit from wide range of anti-cancer drugs
4. Dont forget the vitamin A when working with its carrier protein
5. Variant of vitamin D receptor gene linked to melanoma risk
6. Majority of osteoporosis patients not receiving calcium and vitamin D with treatment
7. Vitamin A pushes breast cancer to form blood vessel cells
8. Researchers identify cancer preventive properties in common vitamin supplement
9. Newborn vitamin A reduces infant mortality
10. New technology may prevent vitamin B12 deficient seniors and vegetarians from needing injections
11. Vitamin D: New way to treat heart failure?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... Angeles, London (April 23, 2014). "I think one can argue ... pathwayas well as doing everything else that we canthen we ... Tom Wigley, one of the world,s foremost climate researchers, in ... , published by SAGE. Refusing to take significant action on ... eventually be needed to address the problem, Wigley explains in ...
(Date:4/22/2014)... 2014 Scientists from the Florida campus of The ... that plays a critical but previously unknown role in ... showed a novel role for a protein known as ... eLife , a publisher supported by the Howard ... Wellcome Trust. , "This is a critical building block ...
(Date:4/22/2014)... have presented Beaumont Health System with prestigious, competitive ... both athletic and nonathletic injuries. , The ... $40,000 grant to fund stem cell-based research that ... a ruptured knee anterior cruciate ligament, or ACL. ... anterior cruciate ligament injury is the over-stretching or ...
Breaking Biology News(10 mins):Is nuclear power the only way to avoid geoengineering? 2Scientists identify critical new protein complex involved in learning and memory 2Beaumont awarded grants to study sports-related injury treatment, improve recovery 2
... long known that the social insects in the ... unusual mechanism for sex determination: Unfertilized eggs develop ... the development of an unfertilized egg into an ... , One mystery has been the origin of ...
... Hospital & Research Center at Oakland (CHRCO) have published a ... cells die in patients with Alzheimer's Disease. This discovery is ... slow, prevent and eventually cure a disease that affects an ... in the February 28th issue of the Proceedings of the ...
... discovered a cluster of 45 genes coding for ... a major cause of hospital-acquired infections worldwide. ... PLoS Genetics. , "We expected to find resistance ... the Structural and Genomic Information Laboratory at France's ...
Cached Biology News:Researchers now able to look deep into heart to view triggers of a heart's beat 2Researchers now able to look deep into heart to view triggers of a heart's beat 3Rice University researchers create 'nanorice' 2Supersized 'island' of resistance genes discovered in an infectious bacterium 2
(Date:1/15/2014)... (PRWEB) January 15, 2014 The Microcompetition with ... major disease. One of these latent viruses is the Epstein ... arthritis (RA). Rheumatoid arthritis (RA) is a chronic inflammatory disease ... a study found that RA patients have high concentrations of ...
(Date:1/15/2014)... 2014 Freeslate, Inc ., the ... that Lupin Limited, one of India’s top five pharmaceutical ... PharmD System for high throughput solid form screening. ... on a wide range of quality, affordable generic and ...
(Date:1/14/2014)... Date: Friday, April 11, 2014 , Time: 6 p.m. – ... Warrington, Pa. , Details: The Hepatitis B Foundation, ... cure for hepatitis B and improving the quality of life ... on Friday, April 11 at Warrington Country Club in Warrington, ...
(Date:1/14/2014)...  3D Communications, a leading provider of strategic communications services to corporations ... in the United States and ... , JD, is returning to the firm,s Washington, D.C. ... after more than two years of service as Associate Commissioner for ...
Breaking Biology Technology:Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2Former FDA Associate Commissioner Returns To 3D Communications 2
... Consulting US, a division of London-based Double Helix ... Stuchiner to the position of Vice President. ... strategic pricing, reimbursement and market access consultants with ... product commercialization services to firms in the pharmaceutical, ...
... Calif., March 30 TorreyPines Therapeutics, Inc. (Nasdaq: ... District Court of the Southern District of New York ... of Axonyx Inc. ("Axonyx") against Axonyx and several of ... in 2006. The plaintiffs alleged that the defendants made ...
... 30 BioMedical Enterprises, Inc. (BME), a rapidly growing ... orthopaedic memory metal implants, announced today that it has ... and Marketing. BME specializes in nitinol implants that ... together to promote bone union. The O ...
Cached Biology Technology:Double Helix Appoints Ann Stuchiner Vice President of US Consulting Division 2Stockholder Suits Related to TorreyPines Therapeutics, Inc. Dismissed 2BioMedical Enterprises, Inc. (BME) Announces the Appointment of Keith M. Peeples as Vice President, Sales and Marketing 2
96 Well Plate Sterile, RE bottom; consistent medium binding affinity for hydrophobic complexes and proteins....
...
The Holten Horizontal series of laminar airflow work benches offers comfort and ease of use....
... Fixed Angle Polypropylene Rotor designed for ... Centra CL3/CL3R** and Centra-MP4/MP4R*. A translucent ... /MP4, ,EXCLUSIVE polypropylene rotor design provides ... repeatedly autoclaved. Polypropylene rotors are ...
Biology Products: