Navigation Links
Vitamin E identified as potential weapon against obesity
Date:4/23/2013

BOSTON A potential new way to fight obesity-related illness has been uncovered, thanks to serendipitous research led by investigators at the Case Western Reserve University School of Medicine.

The collaborators, from Case Western Reserve University, the Cleveland Clinic Foundation and Cornell University, discovered the essential nutrient vitamin E can alleviate symptoms of liver disease brought on by obesity. "The implications of our findings could have a direct impact on the lives of the approximately 63 million Americans who are at potential risk for developing obesity-related liver disease in their lifetimes," says Danny Manor, an associate professor at the Case Western Reserve University School of Medicine.

On Wednesday, April 24, Manor and colleague Varsha Thakur will present the group's findings at the annual meeting of the American Society for Biochemistry and Molecular Biology, held in conjunction with the Experimental Biology 2013 meeting in Boston.

As is often the case in science, Manor's research team at Case Western stumbled upon the findings entirely by accident. While studying the effect of vitamin E deficiency on the central nervous system, "we used liver tissue to practice our surgical techniques," recalled Manor, an associate professor of nutrition and pharmacology. To the team's surprise, they realized that the mice were in fact in the advanced stages of nonalcoholic steatohepatitis. Known as NASH for short, it's a common complication of obesity characterized by fat accumulation, oxidative stress and inflammation in the liver. It is the most severe form of nonalcoholic fatty liver disease and is a major cause of tissue scarring known as cirrhosis that leads to liver failure and may progress to liver cancer.

An essential antioxidant, vitamin E had been shown by recent studies to alleviate some symptoms of NASH in human patients, suggesting that there is a link between adequate vitamin E levels and liver dise
'/>"/>

Contact: Angela Hopp
ahopp@asbmb.org
713-471-4541
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Quit smoking? Vitamin E may give extra boost to heart health
2. Excess vitamin E intake not a health concern
3. Vitamin P as a potential approach for the treatment of damaged motor neurons
4. Vitamin D benefits breathing in tuberculosis patients
5. Living in a sunny climate does not improve vitamin D levels in hip fracture patients
6. Folate and vitamin B12 reduce disabling schizophrenia symptoms in some patients
7. Organic tomatoes accumulate more vitamin C, sugars than conventionally grown fruit
8. Vitamin C is beneficial against the common cold
9. African-American, Caucasian women should take identical vitamin D doses
10. Quantum dots deliver Vitamin D to tumors for possible inflammatory breast cancer treatment
11. Vitamin D holds promise in battling a deadly breast cancer, Saint Louis University researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2014)... --- New research shows that cells are more resilient ... thought. Even when missing critical components, cells can adapt ... way. , In a study published in this week,s ... Michigan State University showed that cells can grow normally ... , "Our genetic information is stored in DNA, which ...
(Date:4/24/2014)... is very pleased to announce that it has assumed ... from the University of Wisconsin. , The ... open-access, peer-reviewed journal that publishes papers on all aspects ... from the molecular to the ecological -- as well ... available to individuals and institutions, and it provides a ...
(Date:4/24/2014)... be improved with new insights into the make-up of ... the Amazon Basin have revealed unprecedented detail of the ... by comparing satellite maps with hundreds of field plots. ... more accurately the amount of carbon each tree can ... schemes, in which trees are given a cash value ...
Breaking Biology News(10 mins):Cell resiliency surprises scientists 2ESA to publish the Journal of Insect Science 2Amazon rainforest survey could improve carbon offset schemes 2
... National Institute of General Medical Sciences, part of the ... Models of Infectious Disease Agent Study for a research ... led by Stephen Eubank, professor. Infectious diseases pose ... worldwide. The Models of Infectious Disease Agent Study (MIDAS) ...
... There might be a time when instead of just drinking ... skin as a way of preventing harmful sun damage or ... caffeine guards against certain skin cancers at the molecular level ... ATR. Scientists believe that based on what they have learned ...
... from NYU Langone Medical Center,s Departments of Orthopaedic Surgery ... used to detect subtle changes in joint cartilage microstructure ... key markers of early osteoarthritis (OA). By using these ... can shift the management of the disease from eventual ...
Cached Biology News:National Institutes of Health renews successful infectious disease research study 2National Institutes of Health renews successful infectious disease research study 3More evidence that caffeine lowers risk of skin cancer 2NYU Langone experts find MRI techniques can detect early osteoarthritis 2
(Date:1/15/2014)... DTS Language Services, Inc . is pleased ... Life Science organizations who need document translations. Clients will ... their documents in advance with a selection of nearly 50 ... often a critical factor in clinical and scientific fields, and ...
(Date:1/15/2014)... Sunnyvale, CA (PRWEB) January 15, 2014 ... throughput research solutions, today announced that Lupin Limited, one ... of Freeslate’s CM Protégé PharmD System for ... in Mumbai, India, is focused on a wide range ...
(Date:1/15/2014)... , Jan. 15, 2014 TaiGen Biotechnology Company, ... exclusive agreement with R-Pharm, a leading Russian pharmaceutical company, ... the Russian Federation , ... Independent States (CIS). Nemonoxacin is a novel antibiotic for the ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Carahsoft and ... Thursday, January 23, 2014 at 2pm EST (11am PST), ... The topic focuses on how technology can turn raw, ... decisions for government agencies. The online webinar will last ...
Breaking Biology Technology:DTS Improves Efficiency for Life Science Document Translations 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2
... the rising trend toward miniaturization, carbon nanotubes which ... and possess several unique and very useful properties ... blocks in nanosized electronic and mechanical devices. But it ... tendency to clump together, that make it difficult for ...
... testament to tight integration and ... excellent ... ), a,leader in radiology and medical image and information management solutions,today ... than 100 facilities that use MEDITECH(TM) as their health,information system. AMICAS ...
... device industry to benefit ... trial recruitment efforts, MINNEAPOLIS, May 27 ... has strengthened the,pharmaceutical side of its business with ... a commitment to leveraging differentiators unique,to the medical ...
Cached Biology Technology:Weizmann Institute scientists create new nanotube structures 2AMICAS Announces Integrations at More Than 100 MEDITECH Facilities 2AMICAS Announces Integrations at More Than 100 MEDITECH Facilities 3ThreeWire Expands Presence in the Pharmaceutical Arena 2
Human Cystatin F MAb (Clone 292103)...
Rat CNTF R alpha Affinity Purified Polyclonal Ab...
... Ac-DEVD-CHO is an inhibitor ... The concentration of inhibitor ... activity must be determined ... Ten micromolar inhibitor is ...
TUNEL Apoptosis Detection Kit...
Biology Products: