Navigation Links
Visualizing biological networks in 4-D
Date:2/11/2013

PASADENA, Calif.Every great structure, from the Empire State Building to the Golden Gate Bridge, depends on specific mechanical properties to remain strong and reliable. Rigiditya material's stiffnessis of particular importance for maintaining the robust functionality of everything from colossal edifices to the tiniest of nanoscale structures. In biological nanostructures, like DNA networks, it has been difficult to measure this stiffness, which is essential to their properties and functions. But scientists at the California Institute of Technology (Caltech) have recently developed techniques for visualizing the behavior of biological nanostructures in both space and time, allowing them to directly measure stiffness and map its variation throughout the network.

The new method is outlined in the February 4 early edition of the Proceedings of the National Academy of Sciences (PNAS).

"This type of visualization is taking us into domains of the biological sciences that we did not explore before," says Nobel Laureate Ahmed Zewail, the Linus Pauling Professor of Chemistry and professor of physics at Caltech, who coauthored the paper with Ulrich Lorenz, a postdoctoral scholar in Zewail's lab. "We are providing the methodology to find outdirectlythe stiffness of a biological network that has nanoscale properties."

Knowing the mechanical properties of DNA structures is crucial to building sturdy biological networks, among other applications. According to Zewail, this type of visualization of biomechanics in space and time should be applicable to the study of other biological nanomaterials, including the abnormal protein assemblies that underlie diseases like Alzheimer's and Parkinson's.

Zewail and Lorenz were able to see, for the first time, the motion of DNA nanostructures in both space and time using the four-dimensional (4D) electron microscope developed at Caltech's Physical Biology Center for Ultrafast Science and T
'/>"/>

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Cornell engineers solve a biological mystery and boost artificial intelligence
2. The neurobiological consequence of predating or grazing
3. UTSA engineer Hai-Chao Han named Fellow of Medical and Biological Engineering Institute
4. A nanoscale window to the biological world
5. Synthetic and biological nanoparticles combined to produce new metamaterials
6. New book details the biological and cultural diversity of Khawa Karpo, sacred mountain of Tibet
7. Developing second skin military fabric to repel chemical and biological agents
8. The Journal of Biological Chemistry commemorates an important 1987 discovery
9. These bots were made for walking: Cells power biological machines
10. Single protein targeted as the root biological cause of several childhood psychiatric disorders
11. Watching the cogwheels of the biological clock in living cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Visualizing biological networks in 4-D
(Date:4/20/2015)... Huntington Memorial Hospital is the first facility ... miniaturized, wireless monitoring sensor to manage heart failure (HF). ... FDA-approved heart failure monitoring device that has been proven ... to manage heart failure. The CardioMEMS HF ... pulmonary artery (PA) during a non-surgical procedure to directly ...
(Date:4/17/2015)... Increasing adoption in ... to drive biometric systems market in ... According to a recently released TechSci Research ... biometric systems market in Saudi Arabia ... CAGR of over 22% through 2020. The market ...
(Date:4/14/2015)... OXFORD, Conn. , April 14, 2015 ... "Company"), a biometric authentication company focused on the growing ... has been nominated for the 2015 New York Design ... The Design100, New York City Design Awards are ... are based on over 2,500 ratings from the marketplace, ...
Breaking Biology News(10 mins):Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 2Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 3Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 2Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 3NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 2NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 3
... Amsterdam, 2 November, 2010 - An investigation conducted in the ... Relevance to Humans, Animals and Ecosystems, demonstrates for the first ... is widespread. In the course of the Summer ... was sampled by mothers who had given birth at the ...
... School meal programs play a significant role in ... comprehensive school nutrition services that improve children,s nutritional ... updated joint position paper from the Society for ... the School Nutrition Association (SNA). The updated ...
... NEW YORK, Nov. 2, 2010 The Online Publishers Association ... Effectiveness of the OPA Ad Unit," that found that 90 ... 10 seconds of being on a webpage and users who ... were as emotionally engaged with the advertising as with the ...
Cached Biology News:Exposure of humans to cosmetic UV filters is widespread 2Exposure of humans to cosmetic UV filters is widespread 3Comprehensive nutrition services vital to children's health 2Online Publishers Association Unveils Biometric and Eye Tracking Research to Assess the Effectiveness of New OPA Ad Units 2Online Publishers Association Unveils Biometric and Eye Tracking Research to Assess the Effectiveness of New OPA Ad Units 3
(Date:4/22/2015)... , April 22, 2015  Sangamo BioSciences, Inc. (NASDAQ: ... financial results and accomplishments. For the first ... net loss of $5.3 million, or $0.08 per share, ... $0.12 per share, for the same period in 2014. ... cash equivalents, marketable securities and interest receivable of $226.1 ...
(Date:4/22/2015)... --  MPIRICA Health Inc. , a healthcare quality ... financing from the McQuinn Trust, an early stage, ... employer awareness of MPIRICA.com, delivering easily interpreted, outcomes-based ... hospitals. "As a patient in need ... choosing the hospital and surgeon most likely to ...
(Date:4/22/2015)... 2015 Steep Hill, the industry leader ... it has opened an investment round of $5 ...  The common stock investment round will be offered ... intended to encourage funding of small businesses by ... businesses largely relied on friends and family, venture ...
(Date:4/22/2015)... 22, 2015 Over the ... market witnessed tremendous growth primarily due to ... government support with increased nanotechnology R&D expenditure ... Customization: , http://www.marketsandmarkets.com/requestCustomization.asp?id=65048077 , In ... market is segmented on the basis of ...
Breaking Biology Technology:Sangamo BioSciences Reports First Quarter 2015 Financial Results 2Sangamo BioSciences Reports First Quarter 2015 Financial Results 3Sangamo BioSciences Reports First Quarter 2015 Financial Results 4Sangamo BioSciences Reports First Quarter 2015 Financial Results 5Sangamo BioSciences Reports First Quarter 2015 Financial Results 6Sangamo BioSciences Reports First Quarter 2015 Financial Results 7Sangamo BioSciences Reports First Quarter 2015 Financial Results 8MPIRICA Health Inc. Secures $1.6M to Promote FICO-Like Quality Scores for Surgeries 2Steep Hill Launches $5M Limited Stock Offering 2Steep Hill Launches $5M Limited Stock Offering 3Nanotechnology-based Medical Devices Market to Reach Around $8.5 billion by 2019 - Published by MarketsandMarkets 2Nanotechnology-based Medical Devices Market to Reach Around $8.5 billion by 2019 - Published by MarketsandMarkets 3
... ... Addressing Dynamic Needs of Growing World , ... Wilmington, DE (Vocus) July 9, 2010 -- The world’s population ... than 12 years -- with more than 9 billion people expected on earth before ...
... ... be present at the Process Expo 2010 in Chicago from July 18 ... designing and manufacturing of industrial wastewater treatment systems for the food processing ... technology and that FRC is a major well-known and respected DAF (Dissolved ...
... from microelectronics to power lines because of their ballistic ... those electrons in their tracks? Rice physicist Junichiro ... effect -- the interaction between electrically charged particles and ... nanotubes. While doing so, they came to the ...
Cached Biology Technology:United Nations' World Population Day Calls Attention to Key Global Issues 2United Nations' World Population Day Calls Attention to Key Global Issues 3United Nations' World Population Day Calls Attention to Key Global Issues 4United Nations' World Population Day Calls Attention to Key Global Issues 5FRC Systems International State-of-the-art Industrial Wastewater Treatment Systems 2FRC Systems International State-of-the-art Industrial Wastewater Treatment Systems 3Magnets trump metallics 2
Rabbit polyclonal antibody to NCOA2 [Agarose Immobilized]...
... and low background ,This solution greatly enhances ... higher than obtained with conventional methods. ,Two ... and secondary antibodies, which can suppress the ... , Wide versatility ,It is applicable to ...
Mouse Anti-Human Killer Cell Immunoglobulin-like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2 (KIR2DL3 Monoclonal Antibody Family: Immunoglobulin Sub-Family: not assigned-Immunogl...
pH-dependent fluorescence; Maximum intensity observed in basic solutions....
Biology Products: