Navigation Links
Visualizing biological networks in 4-D
Date:2/11/2013

PASADENA, Calif.Every great structure, from the Empire State Building to the Golden Gate Bridge, depends on specific mechanical properties to remain strong and reliable. Rigiditya material's stiffnessis of particular importance for maintaining the robust functionality of everything from colossal edifices to the tiniest of nanoscale structures. In biological nanostructures, like DNA networks, it has been difficult to measure this stiffness, which is essential to their properties and functions. But scientists at the California Institute of Technology (Caltech) have recently developed techniques for visualizing the behavior of biological nanostructures in both space and time, allowing them to directly measure stiffness and map its variation throughout the network.

The new method is outlined in the February 4 early edition of the Proceedings of the National Academy of Sciences (PNAS).

"This type of visualization is taking us into domains of the biological sciences that we did not explore before," says Nobel Laureate Ahmed Zewail, the Linus Pauling Professor of Chemistry and professor of physics at Caltech, who coauthored the paper with Ulrich Lorenz, a postdoctoral scholar in Zewail's lab. "We are providing the methodology to find outdirectlythe stiffness of a biological network that has nanoscale properties."

Knowing the mechanical properties of DNA structures is crucial to building sturdy biological networks, among other applications. According to Zewail, this type of visualization of biomechanics in space and time should be applicable to the study of other biological nanomaterials, including the abnormal protein assemblies that underlie diseases like Alzheimer's and Parkinson's.

Zewail and Lorenz were able to see, for the first time, the motion of DNA nanostructures in both space and time using the four-dimensional (4D) electron microscope developed at Caltech's Physical Biology Center for Ultrafast Science and T
'/>"/>

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Cornell engineers solve a biological mystery and boost artificial intelligence
2. The neurobiological consequence of predating or grazing
3. UTSA engineer Hai-Chao Han named Fellow of Medical and Biological Engineering Institute
4. A nanoscale window to the biological world
5. Synthetic and biological nanoparticles combined to produce new metamaterials
6. New book details the biological and cultural diversity of Khawa Karpo, sacred mountain of Tibet
7. Developing second skin military fabric to repel chemical and biological agents
8. The Journal of Biological Chemistry commemorates an important 1987 discovery
9. These bots were made for walking: Cells power biological machines
10. Single protein targeted as the root biological cause of several childhood psychiatric disorders
11. Watching the cogwheels of the biological clock in living cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Visualizing biological networks in 4-D
(Date:6/16/2015)... CITY , June 16, 2015 /CNW Telbec/ ... their partnership centralized around the incorporation of handyem,s ... point-of-care diagnostic laboratory, the Mo-POD™. This unprecedented model ... BIO International Conference at the Pennsylvania ... from June 15 th to 18 ...
(Date:6/15/2015)... , June 15, 2015 A new ... Telstra reveals the majority of US consumers using mobile banking ... biometrics, such as fingerprint and voiceprint, instead of having to ... According to Telstra,s " Mobile Identity   -   The ... report, with smartphones now the primary channel used by Gen ...
(Date:6/9/2015)... MINNETONKA, Minn. , June 9, 2015   ... that supports the entire spectrum of clinical research, will ... eClinical technology platform at the 2015 Drug Information ... on June 15-17.  These presentations will include ... be rolled out in the upcoming iMedNet ...
Breaking Biology News(10 mins):handyem and FlowMetric Diagnostics announce their partnership in the development of Flow Cytometry- Based Solutions in diagnostic capabilities 2handyem and FlowMetric Diagnostics announce their partnership in the development of Flow Cytometry- Based Solutions in diagnostic capabilities 3One in Four US Consumers Would Share Their DNA With Their Bank to Secure Financial and Personal Information, Telstra Report Finds 2One in Four US Consumers Would Share Their DNA With Their Bank to Secure Financial and Personal Information, Telstra Report Finds 3One in Four US Consumers Would Share Their DNA With Their Bank to Secure Financial and Personal Information, Telstra Report Finds 4MedNet To Provide Sneak Peeks Of Its iMedNet "2015 Feature 1 Release" At The DIA Annual Meeting 2MedNet To Provide Sneak Peeks Of Its iMedNet "2015 Feature 1 Release" At The DIA Annual Meeting 3
... -- With thousands of scientists across the globe searching for ... a growing emphasis on finding the "master regulators" that guide ... and the University of Cambridge suggests that a closely connected ... cells (HSCs), the self-renewing cells the body uses to make ...
... lining) and transplanted into the brains of laboratory mice ... cells damaged by the disease, according to a new ... The findings are published in the Journal of ... results, the findings increase the likelihood that endometrial tissue ...
... scientist at the Office of Naval Research, discussed how researchers ... during National Public Radio,s recent "Science Friday" segment. ... microbial fuel cell to power different types of sensors that ... for ONR,s Naval Biosciences and Biocentric Technology Program. "What we,d ...
Cached Biology News:Stem cells: In search of a master controller 2Endometrial stem cells could repair brain cells damaged by Parkinson's disease 2ONR scientist generates 'mud power' for NPR radio audience 2
(Date:7/1/2015)... July 1, 2015 Isagenix International, a leading ... three Gold, three Silver, and three Bronze Stevie® Awards ... in Chicago this month.The ... business awards program in the U.S. ... strength in developing leaders, cultivating talent, creating a unified ...
(Date:7/1/2015)... , July 1, 2015  UCB, a ... ), a global leader in designing, transforming, and ... Innovation Award in recognition of their close collaboration ... in UCB,s global business services (GBS) finance organization. ... providers and clients that work together effectively to ...
(Date:6/30/2015)... , June 30, 2015  NASA astronaut Kjell ... next month on his first mission to the International ... from 8 to 9 a.m. EDT Tuesday, July 7. ... in Star City, Russia . The interviews ... NASA Television highlighting his mission training. To schedule ...
(Date:6/30/2015)... ... June 30, 2015 , ... Noblis, Inc., a ... in a paper published this week in the scientific journal Viruses ( http://www.mdpi.com/1999-4915/7/6/2763 ... techniques currently used to detect the Ebola virus. Noblis worked with the Department ...
Breaking Biology Technology:Isagenix Earns Nine American Business Awards 2Isagenix Earns Nine American Business Awards 3UCB and Genpact Receive Aecus Innovation Award for Success in Global Business Services 2UCB and Genpact Receive Aecus Innovation Award for Success in Global Business Services 3UCB and Genpact Receive Aecus Innovation Award for Success in Global Business Services 4UCB and Genpact Receive Aecus Innovation Award for Success in Global Business Services 5NASA Astronaut Preps for First Space Station Mission, Available for Media Interviews 2Noblis and Government Scientists Identify New Genomic Signatures of Ebola Using Whole Genomic Sequencing and Innovative BioVelocity Analytics Tool 2Noblis and Government Scientists Identify New Genomic Signatures of Ebola Using Whole Genomic Sequencing and Innovative BioVelocity Analytics Tool 3Noblis and Government Scientists Identify New Genomic Signatures of Ebola Using Whole Genomic Sequencing and Innovative BioVelocity Analytics Tool 4
... Cityofparis.us Offers Industry Dialogue, Commentary and How-To, ... Client Collaboration, PALO ALTO, Calif., Sept. 15 ... marketing strategist and communicator, has,launched a new website, ... marketers and communicators can share thinking, gain insights ...
... 3SBio Inc. (Nasdaq:,SSRX), a leading China-based biotechnology ... products, today,announced the results of the shareholder votes ... on September 12, 2008 (Friday) at 10:00 a.m.,(Beijing ... re-elected Dr. Jing Lou,Liping Xu, Bin Huang, Lawrence ...
... Phase in Routine Vaccination Program ... Children -, COLLEGEVILLE, Pa., Sept. 15 ... ), today announced that,South Africa has initiated an ... Conjugated Vaccine,Adsorbed), a vaccine which helps protect infants ...
Cached Biology Technology:South Africa Begins Introduction of PREVENAR into Childhood Immunization Program 2South Africa Begins Introduction of PREVENAR into Childhood Immunization Program 3South Africa Begins Introduction of PREVENAR into Childhood Immunization Program 4
... sample is a complex protein sample, ... when used with ReadyPrep 2-D starter ... sample can be used as a ... and protocol before using more difficult ...
... The Partec Cell Counter Analyser counts ... that the CCA detects only cells, so ... influence the results.,While passing through a 250 ... a fluorescence light signal which is used ...
... peptides, recombinant or native proteins are used to ... protocol optimized in time, quantity of antigen and ... use of 2 animals per protocol in order ... on a 77-day protocol is approximately 75 mL ...
EPA II Buffer is a diluent formulated to stabilize the activity of Chemicon horseradish peroxidase (HRP)-antibody conjugates at high conjugate dilution for extended periods....
Biology Products: