Navigation Links
Versatility of zebrafish research highlighted at international conference
Date:6/21/2012

MADISON, WI June 21, 2012 -- It's clear where the black-and-white striped zebrafish got its name, but less obvious at first glance is what zebrafish has to do with biomedical research. Amazingly, it has biological similarities to humans, which are making this small freshwater fish an increasingly popular model organism for studying vertebrate development, genetics, physiology, and mechanisms of disease.

The variety of presentations at the 2012 International Zebrafish Development and Genetics Conference, held June 20-24 in Madison, Wisconsin, showcase the breadth of research possible with the zebrafish. Many of these studies are aided by its rapid development, genetic malleability, and optical transparency at early stages that enables imaging of labeled cells within a whole, living embryo.

A small sampling of studies drawing on these strengths is highlighted here.

Watching the Birth and Spread of a Cancer

One of a tumor's most dangerous qualities is its ability to metastasize, or spread beyond its original site. The biological mechanisms driving metastasis are an active target of research, often focused on the role of cancer stem cells, which retain a relatively undeveloped state and the ability to multiply.

A research group at Massachusetts General Hospital headed by David Langenau, Ph.D., is advancing this understanding with a surprising twist using a zebrafish model of embryonal rhabdomyosarcoma (ERMS), a rare human pediatric cancer of muscle.

The group, led by postdoctoral researcher Myron Ignatius, Ph.D., engineered the fish to contain fluorescent reporter molecules in their tumor cells. The cells fluoresce green when in the stem cell state, turn red as they begin to differentiate, and finally shine blue once they reach their final differentiated identity within the tumor.

As the fish begin to develop tumors starting at just 10 days old the researchers can take advantage of the trans
'/>"/>

Contact: Phyllis Edelman
pedelman@genetics-gsa.org
301-351-0896
Genetics Society of America
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Environmental estrogens affect early developmental activity in zebrafish
2. Zebrafish could hold the key to understanding psychiatric disorders
3. Better housing conditions for zebrafish could improve research results
4. Autism Speaks awards nearly $2.9 million to fund autism research
5. Researchers advance biometric security
6. University of Tennessee professor receives funding for clean coal research
7. Research could help track stem cells in the body
8. Argonne researchers receive 4 R&D 100 awards
9. CRN assesses current state of scientific research for nutritional supplements
10. University of North Texas Health Science Center Advances Forensic Research by Investing in Semiconductor DNA Sequencing Technology
11. Research identifies specific bacteria linked to indoor water-damage and mold
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/5/2014)... Fidel Santamaria, associate professor of biology in the ... researchers in the nation selected to receive a ... Grant for Exploratory Research (EAGER). The funding supports ... support researchers to create new technology that will ... Santamaria, complex behaviors in neuroscience are broken into ...
(Date:11/4/2014)... right amount of death at the right time might ... new research that could help in understanding animal populations, ... In a paper in the journal Trends in ... European colleagues conclude that the kind of positive population ... individuals, or mortality, depends on the size and developmental ...
(Date:11/4/2014)... , November 4, 2014   ... market growth   Fuel3D , a developer ... a funding round totaling $6.4 million (£4 million). This funding ... secured earlier this year and paves the way for the ... The funding round was led by Chimera Partners ...
Breaking Biology News(10 mins):UTSA biology professor awarded $300,000 NSF grant for brain research 2UTSA biology professor awarded $300,000 NSF grant for brain research 3When less is more: Death in moderation boosts population density in nature 2Fuel3D Secures $6.4 Million in Expansion Funding 2Fuel3D Secures $6.4 Million in Expansion Funding 3
... PHOENIX, Ariz. Feb. 5, 2010 The Translational ... a strategic alliance and affiliation agreement with the Van ... capabilities of both non-profit institutes. TGen expects ... aimed at developing new tests and treatments for patient ...
... study of children in Ukraine has found that for ... care and the relationship between children and their caregivers ... their findings, the researchers highlight the importance of comprehensive ... changing caregivers, working schedules and providing training to enhance ...
... Mich. In an effort to eliminate the tropical ... researcher has been awarded $2 million to reformulate an ... their tracks. Charles Mackenzie, a professor of veterinary ... the funding via a larger $13 million grant the ...
Cached Biology News:TGen finalizes alliance with Van Andel Research Institute 2TGen finalizes alliance with Van Andel Research Institute 3For HIV-infected children, quality of caregiver relationship is crucial 2MSU researcher awarded $2 million to tackle parasitic tropical diseases 2
(Date:11/24/2014)... , Belgium , Nov. 24, 2014 ... sciences company focused on developing diagnostic tests for cancer and ... cancer study will be presented at the Science for Business ... Belgium . The data come from VolitionRx,s ... at the Pneumology department of the Centre Hospitalier Universitaire (CHU) ...
(Date:11/24/2014)... (PRWEB) November 24, 2014 2014 ... Dihydrazide Industry is a professional and in-depth research ... Adipic Dihydrazide information, like its definition, classification, application, ... overview. This report covers the international market analysis, ... (such as the US, Europe, Asia, China, Japan ...
(Date:11/22/2014)... (PRWEB) November 21, 2014 Two new educational ... what comes next for ALS research and how the pharmaceutical ... After the Ice Bucket Challenge: Where Does the ALS Money ... Tuesday, 2 December 2014, Time: 1:30pm ET, Register ... expert speaker Dr. Merit Cudkowicz, Julianne Dorn Professor of Neurology ...
(Date:11/22/2014)... On November 17th Chicago start-up Briteseed ... Medical Technologies Summit in San Francisco to take first ... among Silicon Valley investors and technology elites as the ... also positions Briteseed to move on to the ... and compete with other elite innovation finalists for a ...
Breaking Biology Technology:VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 2VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 3VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 4VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 5VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 6Adipic Dihydrazide Industry 2019 Research Forecasts on Worldwide, China Regions Now Available at ReportsnReports.com 2Adipic Dihydrazide Industry 2019 Research Forecasts on Worldwide, China Regions Now Available at ReportsnReports.com 3DrugDev Webinars in December to Explore What Comes Next for ALS Research and How We Can Make Life Easier for Clinical Sites 2Insight Product Development Accelerator Member Wins MedTech Innovator Award Competition 2Insight Product Development Accelerator Member Wins MedTech Innovator Award Competition 3
... Presentation Scheduled for Monday, March 17th at 11:30am ET, ... KERX ) today announced that I. Craig Henderson, ... Vice President,Medical Affairs, are scheduled to present at the ... The presentation, which will take place on Monday, ...
... Phase 2 Clinical Trial in ... ... today financial results for the year ended December,31, 2007, and highlighted the ... ), During 2007, the Company achieved the following corporate milestones:, ...
... for ... cars, phones, computers, ARGONNE, Ill., ... Laboratory and Toda Kogyo Corp. (Toda) of Japan have,reached a ... patented composite cathode materials for lithium-ion,batteries, which result in longer-lasting, ...
Cached Biology Technology:Keryx Biopharmaceuticals to Present at the Cowen and Company 28th Annual Health Care Conference 2Nventa Biopharmaceuticals Reports Full Year 2007 and Fourth Quarter Financial Results 2Nventa Biopharmaceuticals Reports Full Year 2007 and Fourth Quarter Financial Results 3Nventa Biopharmaceuticals Reports Full Year 2007 and Fourth Quarter Financial Results 4Nventa Biopharmaceuticals Reports Full Year 2007 and Fourth Quarter Financial Results 5Nventa Biopharmaceuticals Reports Full Year 2007 and Fourth Quarter Financial Results 6Nventa Biopharmaceuticals Reports Full Year 2007 and Fourth Quarter Financial Results 7Argonne's Lithium-Ion Battery Technology to be Commercialized by Japan's Toda Kogyo 2Argonne's Lithium-Ion Battery Technology to be Commercialized by Japan's Toda Kogyo 3
MAb to Yersinia pestis F1 Ag. Yersinia pestis F1 Antigen EB Strain...
... FluoroGuard antifade reagent is ... confocal and standard fluorescence microscopy. ... photobleaching in a wide variety ... labeled with fluorescein, rhodamine, sulforhodamine ...
... UN-SCAN-IT gel Software converts any scanner ... has numerous options and features, the basic ... (TIFF, JPEG, PCX, BMP, etc.) into pixel ... simple steps. Turn your ...
... RED Chromogen System consists of FAST RED ... in the presence of alkaline phosphatase to ... The FAST RED System provides enough ... Contains: , , Vial A: 6 Tablets ...
Biology Products: