Navigation Links
Versatility of zebrafish research highlighted at international conference
Date:6/21/2012

MADISON, WI June 21, 2012 -- It's clear where the black-and-white striped zebrafish got its name, but less obvious at first glance is what zebrafish has to do with biomedical research. Amazingly, it has biological similarities to humans, which are making this small freshwater fish an increasingly popular model organism for studying vertebrate development, genetics, physiology, and mechanisms of disease.

The variety of presentations at the 2012 International Zebrafish Development and Genetics Conference, held June 20-24 in Madison, Wisconsin, showcase the breadth of research possible with the zebrafish. Many of these studies are aided by its rapid development, genetic malleability, and optical transparency at early stages that enables imaging of labeled cells within a whole, living embryo.

A small sampling of studies drawing on these strengths is highlighted here.

Watching the Birth and Spread of a Cancer

One of a tumor's most dangerous qualities is its ability to metastasize, or spread beyond its original site. The biological mechanisms driving metastasis are an active target of research, often focused on the role of cancer stem cells, which retain a relatively undeveloped state and the ability to multiply.

A research group at Massachusetts General Hospital headed by David Langenau, Ph.D., is advancing this understanding with a surprising twist using a zebrafish model of embryonal rhabdomyosarcoma (ERMS), a rare human pediatric cancer of muscle.

The group, led by postdoctoral researcher Myron Ignatius, Ph.D., engineered the fish to contain fluorescent reporter molecules in their tumor cells. The cells fluoresce green when in the stem cell state, turn red as they begin to differentiate, and finally shine blue once they reach their final differentiated identity within the tumor.

As the fish begin to develop tumors starting at just 10 days old the researchers can take advantage of the trans
'/>"/>

Contact: Phyllis Edelman
pedelman@genetics-gsa.org
301-351-0896
Genetics Society of America
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Environmental estrogens affect early developmental activity in zebrafish
2. Zebrafish could hold the key to understanding psychiatric disorders
3. Better housing conditions for zebrafish could improve research results
4. Autism Speaks awards nearly $2.9 million to fund autism research
5. Researchers advance biometric security
6. University of Tennessee professor receives funding for clean coal research
7. Research could help track stem cells in the body
8. Argonne researchers receive 4 R&D 100 awards
9. CRN assesses current state of scientific research for nutritional supplements
10. University of North Texas Health Science Center Advances Forensic Research by Investing in Semiconductor DNA Sequencing Technology
11. Research identifies specific bacteria linked to indoor water-damage and mold
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... its launch in December 2014, the 1U™ app ... trying to remember their usernames and passwords through replacing the ... To assist people who have struggled to remember usernames and ... and focuses on redefining identity, announced today that it is ...
(Date:12/22/2014)... 2014  The 2014 Holiday Season may be the brightest ... reports that the long anticipated floodgates for consumer biometrics ... for smart phones, tablets, and wearable mobile devices that ... billion users with nearly 4.8 billion biometric devices by ...
(Date:12/19/2014)... Inc., the leading personal genetics company, today announced the publication ... of individuals from across the United States ... hundred years ago, the United States ... continents. This study illuminates how American history and the ongoing ...
Breaking Biology News(10 mins):1U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 223andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4
... #1 FOR IMMEDIATE RELEASE Wine in a box? Think ... Chemistry In a surprise discovery that ... gauche alternative to bottles, scientists in Canada are reporting that ... substances that contribute odors to wine and can lower its ...
... not only effect the environment via their exhaust pipes. ... with getting from a to b that we rarely ... Research Letters , Monday, June 8, 2009, researchers from ... University of California, Berkeley, have created a framework to ...
... , GREENVILLE, S.C., June 3 Integrated Biometrics, a leading ... Charles Johnson to its sales staff. Johnson is a ... and had previously worked at Integrated Biometrics in 2006. ... Chair of the local ASIS Chapter. , , "As ...
Cached Biology News:American Chemical Society's Weekly PressPac -- June 3, 2009 2American Chemical Society's Weekly PressPac -- June 3, 2009 3American Chemical Society's Weekly PressPac -- June 3, 2009 4American Chemical Society's Weekly PressPac -- June 3, 2009 5American Chemical Society's Weekly PressPac -- June 3, 2009 6American Chemical Society's Weekly PressPac -- June 3, 2009 7American Chemical Society's Weekly PressPac -- June 3, 2009 8American Chemical Society's Weekly PressPac -- June 3, 2009 9American Chemical Society's Weekly PressPac -- June 3, 2009 10More than just the tailpipe 2Integrated Biometrics Adds Security Industry Veteran to Sales Staff 2
(Date:1/22/2015)... 2015 Selexis SA, a serial innovation ... Banks (RCBs) used for drug discovery to commercial manufacturing, ... include Next-Generation Sequencing (NGS) data packages. The ... manufacturing by ensuring the integrity of the gene, validation ...
(Date:1/22/2015)... GenoSpace , a precision medicine software company that has developed ... of genomic, imaging and other biomedical data in research and ... , CEO of Aspera, an IBM Company, to its board ... "We are pleased to welcome Michelle ...
(Date:12/24/2014)...  Vermillion, Inc. (Nasdaq:   VRML), a bio-analytical solutions ... the Company closed its previously announced private placement ... W. Schuler , Birchview Fund LLC and several ... offering expenses.  The proceeds will be used for ...
(Date:12/24/2014)... SoundConnect’s 2015 next ... edge communication technology, provide continued education and inform ... series demonstrates online communication features and benefits; empowering ... most innovative and powerful tools. , According to ...
Breaking Biology Technology:Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2GenoSpace Expands Board with Appointment of Michelle Munson 2Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3
... New Releases for the Company Building on Milestones ... April 20 DXL625 monoclonal antibodies ... their ability to attach and deplete NHL in ... at InNexus Biotechnology Inc. (Toronto Stock Exchange: IXS.V, ...
... Xennex Inc. (Xennex) announced today that it ... provided Satoris with access to GeneCards(R) and associated ... input from the advanced prototype of GeneCards(R) version ... Satoris is utilizing GeneCards and the related technology ...
... groups including the mentally ill, the disabled and ... fare worse than others in the aftermath of natural ... , Now, a new study by UCLA researchers ... terrorism-related fears and make more behavioral changes based on ...
Cached Biology Technology:AACR 100th Annual Meeting Highlights Superior Ability of InNexus' DXL-Modified Anti-CD20 Antibody to Attach and Kill NHL With Safety Comparable to Approved Antibody Therapies in Preclinical Studies 2AACR 100th Annual Meeting Highlights Superior Ability of InNexus' DXL-Modified Anti-CD20 Antibody to Attach and Kill NHL With Safety Comparable to Approved Antibody Therapies in Preclinical Studies 3Xennex Inc. Providing Satoris Inc. with Latest GeneCards(R) Tools for Characterization of Protein Biomarkers Associated With Neurological Conditions 2Xennex Inc. Providing Satoris Inc. with Latest GeneCards(R) Tools for Characterization of Protein Biomarkers Associated With Neurological Conditions 3Disabled and other vulnerable groups more susceptible to terrorism fears 2
Rabbit anti Xanthine Oxidase Xanthine Oxidase, Bovine Buttermilk...
... SilverSNAP Stain for Mass Spectrometry Applications ... spectrometry (MS) has emerged as a powerful ... of 2-D gels is now an important ... that leads ultimately to identification of specific ...
... Extraction Reagent is a liquid, ... means no scraping, no freeze-thaw ... M-PER Reagent, rapid lysis occurs ... room temperature, yielding 25% more ...
... Kits with ammonium sulfate are compatible with ... as Tfl, Tth, and Pfu DNA polymerases. ... PCR systems in one experiment by adding ... into the PreMixes supplied with the kit. ...
Biology Products: