Navigation Links
VTT searches for novel biomarkers and targets for preventing or treating Type 2 diabetes
Date:2/21/2012

VTT is participating in two new European projects focusing on type 2 diabetes. The projects aim at identifying new therapeutic choices and strategies for preventing the disease. Focus is on obtaining information on cellular dysfunction in diabetes and the effects of changes in lifestyle. The goal includes planning individual lifestyle instructions for people at high risk of diabetes and exploiting the results in a major European health insurance system.

The EU BetaBAT project aims at developing individual therapeutic choices for type 2 diabetics by identifying the connection between the genome and individual cell-level changes causing the disease. The scientists will use systems biological tools to boost the capacity of beta cells and brown adipocytes for regaining homeostatic control.

The other EU project, DEXLIFE, aims at disease prevention by identifying novel diagnostic and predictive biomarkers to detect the progression toward type 2 diabetes in individuals at high risk of the disease. Large-scale data will be acquired during the project, including information on genes and metabolites. The intervention aiming at type 2 diabetes prevention will be set up in the real-life context of a major European health insurance system.

In both projects VTT leads the work packages on integration and modelling of data. VTT has a central role in applying systems biology strategies including metabolomics, integrative bioinformatics and biosystems modelling to identify putative organelle-specific targets (BetaBAT) and early predictive markers of type 2 diabetes progression (DEXLIFE).

The global prevalence of diabetes has reached 285 million and is projected to rise to 435 million by 2030. Type 2 diabetes is preventable by sustained changes in diet and physical exercise. Despite this, modern societies are already approaching 10% population prevalence of diabetes, and another 15% with pre-diabetes. The costs of type 2 diabetes are huge, a
'/>"/>

Contact: Matej Oresic
matej.oresic@vtt.fi
358-207-224-491
VTT Technical Research Centre of Finland
Source:Eurekalert

Page: 1 2

Related biology news :

1. UK robot sub searches for signs of melting 60 km into an Antarctic ice shelf cavity
2. Trauma drama: K-State professor researches drama queen of immune system
3. A Spanish botanist searches for prehistoric flora refuges in China
4. AZTI-Tecnalia researches the use of vegetable by-products for animal feed
5. Scientists identify novel inhibitor of human microRNA
6. Conaway Lab identifies novel mechanism for regulation of gene expression
7. LIAI launches new division to look at novel approaches to heart disease and inflammation
8. Childrens National researchers develop novel anti-tumor vaccine
9. Cold Spring Harbor Laboratory scientists trace a novel way cells are disrupted in cancer
10. Novel publishing approach puts textbook in more hands
11. GEN reports on novel tools for deciphering biological networks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/24/2015)... Africa , August 24, 2015 ... Germany ,s largest biometrics manufacturer DERMALOG and its customized ... the "2015 African Biometrics Company of the Year Award". DERMALOG ... Nigeria .   -Cross reference: Picture ... http://www.presseportal.de/nr/8896 - On Thursday evening, in ...
(Date:8/20/2015)... 2015   Sensory, Inc ., a Silicon ... experience and security of consumer electronics through state-of-the-art ... its TrulySecure™ is the first multimodal ... FIDO Certified™. The FIDO (Fast Identification ... FIDO UAF (Universal Authentication Framework) 1.0 specifications, which ...
(Date:8/18/2015)... , Aug. 18, 2015  Navitas ... key contributor to the Submission Content Management ... IRISS, a non-profit forum. Dedicated to the Implementation ... a neutral platform for industry, vendors, health ... information and work towards a standard method ...
Breaking Biology News(10 mins):Frost & Sullivan Honors DERMALOG with Biometrics Prize for Achievements in Africa 2Frost & Sullivan Honors DERMALOG with Biometrics Prize for Achievements in Africa 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 2TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 4TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 5Navitas, a Key Contributor in IRISS Forum Webinar 2Navitas, a Key Contributor in IRISS Forum Webinar 3
... 2011 Reportlinker.com announces that a new ... catalogue: Enzymes in Drug ... Biocatalysis in pharmaceutical manufacturing is ... genomics technologies that are increasing the breadth ...
... by researchers at the European Centre for the Environment and ... Medicine and Dentistry) and the University of Birmingham has compared ... and concluded that the development of accurate simulations are likely ... because of infirmity or other limitations: but virtual worlds ...
... developed a new synchrotron X-ray technique that may revolutionize the ... fossils. The results have been published on 29 May 2011 ... Life, as we know it, is based on the ... abundance and chemical bonds has been difficult to study up ...
Cached Biology News:Reportlinker Adds Enzymes in Drug Manufacturing 2Reportlinker Adds Enzymes in Drug Manufacturing 3Reportlinker Adds Enzymes in Drug Manufacturing 4Reportlinker Adds Enzymes in Drug Manufacturing 5Reportlinker Adds Enzymes in Drug Manufacturing 6Virtual natural environments and benefits to health 2Virtual natural environments and benefits to health 3Virtual natural environments and benefits to health 4New synchrotron technique could see hidden building blocks of life 2
(Date:8/31/2015)...  For people with Down syndrome, news from ... company, located in the Science + Technology Park at ... therapies yet for people with Down syndrome and other chromosome ... syndrome and Edwards syndrome aneuploidies in human cell cultures, ... Elixirgen plans to develop this technology into a treatment ...
(Date:8/31/2015)... , Aug. 31, 2015  US-Australian drug ... NVGN ) today confirmed its comprehensive scientific review ... technology platforms in areas of unmet patient need. ... the remaining preclinical projects prior to entering into ... compounds. Acting Chief Executive Officer, ...
(Date:8/31/2015)... , Aug. 31, 2015 LabStyle Innovations ... Management Solution, today announced it recently closed a ... will be used to support the global rollout ... a mobile, cloud-based, diabetes management solution that includes ... pocket-sized, blood glucose monitoring device, and for working ...
(Date:8/31/2015)... ... August 31, 2015 , ... The ... successful food and beverage processors, equipment manufacturers and leaders in the field of ... industrial weighing and formulation for manufacturers of bakery and snacks; beverages; dairy; meat, ...
Breaking Biology Technology:New Down syndrome therapy discovered 2Novogen Announces The Outcome Of A Comprehensive Science Review 2Novogen Announces The Outcome Of A Comprehensive Science Review 3Novogen Announces The Outcome Of A Comprehensive Science Review 4Novogen Announces The Outcome Of A Comprehensive Science Review 5Novogen Announces The Outcome Of A Comprehensive Science Review 6LabStyle Innovations Closes $2.5 Million Funding to Support Global Rollout of Dario Diabetes Management Solution 2LabStyle Innovations Closes $2.5 Million Funding to Support Global Rollout of Dario Diabetes Management Solution 3LabStyle Innovations Closes $2.5 Million Funding to Support Global Rollout of Dario Diabetes Management Solution 4METTLER TOLEDO Hosts Food Safety Educational Center at 2015 PROCESS EXPO 2
... - The Wisconsin Legislature has passed a bill that ... to commercialize their discoveries, but two other bills endorsed ... the remainder of the 2005-07 legislative session. , ,On ... Senate enacted their respective versions of Senate Bill 338, ...
... Wisconsin-Madison researchers have until June 1 to submit ... to stimulate collaborative research projects. , ,The Wisconsin ... $3 million in private funding to encourage collaborative research ... advance of the institutes' opening in late 2009. The ...
... Moving past the balkanization of information technology in healthcare ... the Digital Healthcare Conference 2006 . And vendors ... by informed customers. , ,Providers are facing that common ... a patchwork of vendors and systems with challenges agreeing ...
Cached Biology Technology:Legislature adopts one tech bill, leaves two others twisting 2Legislature adopts one tech bill, leaves two others twisting 3Legislature adopts one tech bill, leaves two others twisting 4UW-Madison sets June 1 deadline for research proposals 2Being proactive with vendors helps healthcare improve IT 2
Alexa Fluor 647 anti-mouse Qa-2...
... essential for hunting and analyzing the ... as EST sequencing projects, microarrays, functional ... is developed for normalization of cDNA ... for directional cloning. While most normalization ...
... acquision and analysis software for ... applications. Contains powerful stimulus generation ... functions including automated waveform feature ... includes many electrophysiology specific functions ...
normal human fibroblasts Source: Cell Lysate Form: Ready to Use Application: Western Blotting Control...
Biology Products: