Navigation Links
VTT searches for novel biomarkers and targets for preventing or treating Type 2 diabetes
Date:2/21/2012

VTT is participating in two new European projects focusing on type 2 diabetes. The projects aim at identifying new therapeutic choices and strategies for preventing the disease. Focus is on obtaining information on cellular dysfunction in diabetes and the effects of changes in lifestyle. The goal includes planning individual lifestyle instructions for people at high risk of diabetes and exploiting the results in a major European health insurance system.

The EU BetaBAT project aims at developing individual therapeutic choices for type 2 diabetics by identifying the connection between the genome and individual cell-level changes causing the disease. The scientists will use systems biological tools to boost the capacity of beta cells and brown adipocytes for regaining homeostatic control.

The other EU project, DEXLIFE, aims at disease prevention by identifying novel diagnostic and predictive biomarkers to detect the progression toward type 2 diabetes in individuals at high risk of the disease. Large-scale data will be acquired during the project, including information on genes and metabolites. The intervention aiming at type 2 diabetes prevention will be set up in the real-life context of a major European health insurance system.

In both projects VTT leads the work packages on integration and modelling of data. VTT has a central role in applying systems biology strategies including metabolomics, integrative bioinformatics and biosystems modelling to identify putative organelle-specific targets (BetaBAT) and early predictive markers of type 2 diabetes progression (DEXLIFE).

The global prevalence of diabetes has reached 285 million and is projected to rise to 435 million by 2030. Type 2 diabetes is preventable by sustained changes in diet and physical exercise. Despite this, modern societies are already approaching 10% population prevalence of diabetes, and another 15% with pre-diabetes. The costs of type 2 diabetes are huge, a
'/>"/>

Contact: Matej Oresic
matej.oresic@vtt.fi
358-207-224-491
VTT Technical Research Centre of Finland
Source:Eurekalert

Page: 1 2

Related biology news :

1. UK robot sub searches for signs of melting 60 km into an Antarctic ice shelf cavity
2. Trauma drama: K-State professor researches drama queen of immune system
3. A Spanish botanist searches for prehistoric flora refuges in China
4. AZTI-Tecnalia researches the use of vegetable by-products for animal feed
5. Scientists identify novel inhibitor of human microRNA
6. Conaway Lab identifies novel mechanism for regulation of gene expression
7. LIAI launches new division to look at novel approaches to heart disease and inflammation
8. Childrens National researchers develop novel anti-tumor vaccine
9. Cold Spring Harbor Laboratory scientists trace a novel way cells are disrupted in cancer
10. Novel publishing approach puts textbook in more hands
11. GEN reports on novel tools for deciphering biological networks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... Non-biting blow fly Chrysomya megacephala is commonly ... investigations to determine the time of death, referred to ... derived form of C. megacephala from Tamil ... morphological features and molecular characterization through generation of DNA ... in the open access Biodiversity Data Journal . ...
(Date:7/23/2014)... the world by 2050, according to one of the ... (IPCC), may be advantageous to the physiology and the ... forage plants such as Stylosanthes capitata Vogel , ... such as Brazil., The conclusion is from a study ... at the Ribeiro Preto Faculty of Philosophy, Sciences and ...
(Date:7/23/2014)... publish the International Journal of Fuzzy Systems ... Fuzzy Systems Association (TFSA). The cooperation will allow the ... of fuzzy research., The International Journal of Fuzzy ... deal with the theory, design and application of fuzzy ... systems ranging from hardware to software. Launched in 1999, ...
Breaking Biology News(10 mins):Dead body feeding larvae useful in forensic investigations 2An increase in temperature by 2050 may be advantageous to the growth of forage plants 2An increase in temperature by 2050 may be advantageous to the growth of forage plants 3An increase in temperature by 2050 may be advantageous to the growth of forage plants 4
... journal Acta Biomaterialia , researchers from the University of ... in the grafting of stem cells onto the eye, mimicking ... designed to treat damage to the cornea, the transparent layer ... the major causes of blindness in the world. Using ...
... PRUSSIA, Pa., Dec. 4, 2012 /PRNewswire-iReach/ -- Greenphire CEO ... Spend Bootcamp on the implications of the Physician Sunshine ... on advances in technology which streamlines financial reporting required ... discussion focused on how pharmaceutical, biotech, and medical device ...
... a professor of entomology at the University ... California Citrus Quality Council ,s prestigious Albert G. ... in the field of entomology which has contributed vitally ... three decades, Morse has provided timely research results and ...
Cached Biology News:New technique to deliver stem cell therapy may help damaged eyes regain their sight 2Greenphire CEO Sam Whitaker speaks on Sunshine Act and Clinical Trial Payments 2UC Riverside entomologist recognized for research in citrus entomology 2
(Date:7/23/2014)... , July 24, 2014 Lyfebulb, ... Pharmaceuticals Inc. (OTCQX and NASDAQ OMX First North ... or "the Company"), announced a collaboration to increase ... last night at an event attended by more ... parties. Lyfebulb is a health and wellness company ...
(Date:7/23/2014)... made great strides in saving China,s endangered national treasure, ... 65 giant panda reserves that have been established and ... 1596 pandas remain in the wild. , Breeding ... the panda by improving genetic diversity, avoid inbreeding and ... are these high-profile programs doing so far? , In ...
(Date:7/23/2014)... , July 23, 2014 /PRNewswire-iReach/ -- Think Drinks ... performance for the long term. They are the first ... of sustained energy as an alternative to the temporary ... Drinks on Indiegogo on July 29, 2014, with hopes ... campaign. Photo - http://photos.prnewswire.com/prnh/20140723/129697 ...
(Date:7/23/2014)... Last year, Formedix celebrated ... global provider of data management solutions for clinical trials. ... system for electronic data capture (EDC) and clinical data ... study execution tools added TrialMaster to its Transform for ... of Transform for TrialMaster, is being released this week, ...
Breaking Biology Technology:Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 2Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 3Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 4Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 5truBrain Neuroscientists To Launch More Effective, Healthier Alternative To Energy Drinks On Indiegogo 2Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 2Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 3
... Hikma Pharmaceuticals today,announced strong revenue growth and stable ... business. The weakness in the US was offset by ... Branded,businesses. CEO, Said Darwazah, said "The US operations, in ... we had a loss there so in spite of,this ...
... of Helsinki, Finland, has succeeded in producing nano-sized metallic ... to a nano-scale (one nanometre being one billionth of ... changes. Unlike in bulk materials, in nanoparticles the number ... of atoms inside the material, which, among other things, ...
... SOUTHAMPTON, Pa., March 16 Environmental Tectonics Corporation ... "Company") today announced that their BioMedical Division will ... Conference. The American Professional Wound Care Association (APWCA) ... - 4 in Philadelphia, at the Sheraton, Philadelphia, ...
Cached Biology Technology:Paper electrified by copper particles 2Environmental Tectonics Corporation Announces Participation at APWCA National Conference 2Environmental Tectonics Corporation Announces Participation at APWCA National Conference 3
Rabbit polyclonal to Vitronectin ( Abpromise for all tested applications). Antigen: Full length Vitronectin protein (Mouse). Entrez Gene ID: 7448 Swiss Protein ID: P04004...
... LNA technology enables sensitive and specific detection ... miRCURY LNA in situ detection probes have ... specific and sensitive detection of miRNAs. Specific ... in whole mounts, thin sections, single cells ...
... complete kit contains enough separation ... a total of 5 x ... includes the StemSep red magnet ... and buffers for the specific ...
... Product Mouse monoclonal [1320] to ... the p37 subunit of human Replication Factor C ... Cross-reacts with Human and S. cerevisiae. Not ... the p37 subunit of RFC1 Background ...
Biology Products: