Navigation Links
VTT searches for novel biomarkers and targets for preventing or treating Type 2 diabetes
Date:2/21/2012

VTT is participating in two new European projects focusing on type 2 diabetes. The projects aim at identifying new therapeutic choices and strategies for preventing the disease. Focus is on obtaining information on cellular dysfunction in diabetes and the effects of changes in lifestyle. The goal includes planning individual lifestyle instructions for people at high risk of diabetes and exploiting the results in a major European health insurance system.

The EU BetaBAT project aims at developing individual therapeutic choices for type 2 diabetics by identifying the connection between the genome and individual cell-level changes causing the disease. The scientists will use systems biological tools to boost the capacity of beta cells and brown adipocytes for regaining homeostatic control.

The other EU project, DEXLIFE, aims at disease prevention by identifying novel diagnostic and predictive biomarkers to detect the progression toward type 2 diabetes in individuals at high risk of the disease. Large-scale data will be acquired during the project, including information on genes and metabolites. The intervention aiming at type 2 diabetes prevention will be set up in the real-life context of a major European health insurance system.

In both projects VTT leads the work packages on integration and modelling of data. VTT has a central role in applying systems biology strategies including metabolomics, integrative bioinformatics and biosystems modelling to identify putative organelle-specific targets (BetaBAT) and early predictive markers of type 2 diabetes progression (DEXLIFE).

The global prevalence of diabetes has reached 285 million and is projected to rise to 435 million by 2030. Type 2 diabetes is preventable by sustained changes in diet and physical exercise. Despite this, modern societies are already approaching 10% population prevalence of diabetes, and another 15% with pre-diabetes. The costs of type 2 diabetes are huge, a
'/>"/>

Contact: Matej Oresic
matej.oresic@vtt.fi
358-207-224-491
VTT Technical Research Centre of Finland
Source:Eurekalert

Page: 1 2

Related biology news :

1. UK robot sub searches for signs of melting 60 km into an Antarctic ice shelf cavity
2. Trauma drama: K-State professor researches drama queen of immune system
3. A Spanish botanist searches for prehistoric flora refuges in China
4. AZTI-Tecnalia researches the use of vegetable by-products for animal feed
5. Scientists identify novel inhibitor of human microRNA
6. Conaway Lab identifies novel mechanism for regulation of gene expression
7. LIAI launches new division to look at novel approaches to heart disease and inflammation
8. Childrens National researchers develop novel anti-tumor vaccine
9. Cold Spring Harbor Laboratory scientists trace a novel way cells are disrupted in cancer
10. Novel publishing approach puts textbook in more hands
11. GEN reports on novel tools for deciphering biological networks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2015)... 24, 2015 Research and Markets ( http://www.researchandmarkets.com/research/kvdtcw/face_and_voice ) ... - Global Strategic Business Report" report to their offering. ... Biometrics in US$ Thousands by the following Segments: Face Biometrics, and ... Canada , Japan , ... Middle East & Africa , and ...
(Date:3/23/2015)... BOSTON, Mass , March 23, 2015 SoundView ... shipment of NXT-ID,s (NASDAQ: NXTD ) Wocket smart wallet. SoundView ... world user feedback on their experience with the Wocket in ... experience at CVS, Whole Foods and other retailers, making both ... Kris Tuttle also says, "If the company meets ...
(Date:3/23/2015)... OXFORD, Conn. , Mar. 23, 2015 NXT-ID, Inc. ... authentication company focused on the growing mobile commerce market, announces ... a new advertising campaign on CNBC television starting March 30 ... ads will commence airing in New York ... Executive Officer said: "We are excited about our new ad ...
Breaking Biology News(10 mins):Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 3Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 4Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 5Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 6Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 3
... appearing in the May issue of The Journal of ... account for when examining dinosaur tracks. The authors studied ... dinosaurs that includes the T. Rex and the tridactyl, ... many different types of erosion on these invaluable impressions. ...
... resulting from farming argue for a shift toward ... energy and more recycling of energy and materials, ... 2007 issue of BioScience. The author, Craig J. ... semiclosed agricultural systems -- which he terms "regenerative" ...
... of the online, open-access journal PLoS ONE, shows that although ... are also large areas of forests regenerating. The return of ... area, with an overall net increase of 4 % during ... of plant endemism (species found only in a particular region) ...
Cached Biology News:How to look at dinosaur tracks 2Madagascan tropical forests return thanks to better management and well-defined ownership 2
(Date:4/24/2015)... Seoul Semiconductor announced the expansion of its ... lighting market. In recent months, there have ... emerging markets such as Russia, South America, and ... such as streetlight and area lighting, tunnel lighting, ... in 2005 the Acrich technology from Seoul Semiconductor ...
(Date:4/23/2015)... , April 23, 2015 BioTE Medical ... his book "Age Healthier Live Happier - Avoiding Over-Medication ... the Age Management Medicine Group Conference at JW Marriott ... 2015. ",Age Healthier Live Happier, is a ... avoid over-medication and searching for a higher quality of ...
(Date:4/23/2015)... 23, 2015  Cryoport, Inc. (OTCBB: CYRX) ("Company"), ... for the life sciences industry, today announced that ... solutions within the animal husbandry market by signing ... support the shipment of equine semen for artificial ... Stallions. Animal husbandry is a multi-billion ...
(Date:4/23/2015)... April 23, 2015  Metanome, Inc., an industry ... company has changed its name to Diversigen, Inc.  ... as the single commercial source for the myriad ... on the diverse opportunities of the microbiome.  From ... accepts – including those that are difficult to ...
Breaking Biology Technology:Acrich Technology from Seoul Semiconductor Adopted in Installations Worldwide 2Release and Book Signing of BioTE Medical President Gary Donovitz M.D. 'Age Healthier Live Happier' at Age Management Medicine Group (AMMG) Conference 2Release and Book Signing of BioTE Medical President Gary Donovitz M.D. 'Age Healthier Live Happier' at Age Management Medicine Group (AMMG) Conference 3Cryoport to Support the Equine Animal Husbandry Market Through Agreement with Yancey Farms 2Cryoport to Support the Equine Animal Husbandry Market Through Agreement with Yancey Farms 3Metanome Announces Corporate Name Change to Diversigen 2
... Experience To Antimicrobial Leader.SHREVEPORT, La., March 23 ... in the poultry industry, has joined SteriFx Inc. ... to SteriFx, a leader in developing non-toxic antimicrobial ... defense and other industries. "We,re honored and thrilled ...
... DIEGO, March 23 Nereus Pharmaceuticals, Inc., a ... today announced that it is conducting a randomized ... agent (VDA) NPI-2358 in combination with standard chemotherapy ... (NSCLC). This study follows on positive outcomes ...
... Based on its recent analysis of ... Sullivan presents Nanopoint, Inc. with the 2009 ... Product Innovation of the Year. The company,s ... sophisticated, on-microscope incubator and integrated fluidics system ...
Cached Biology Technology:Dan Blackshear Joins SteriFx Inc. 2Nereus Pharmaceuticals Initiates ADVANCE, a Randomized Phase 2 Clinical Trial of NPI-2358 in Non-Small Cell Lung Cancer 2Nereus Pharmaceuticals Initiates ADVANCE, a Randomized Phase 2 Clinical Trial of NPI-2358 in Non-Small Cell Lung Cancer 3Frost & Sullivan Recognizes Nanopoint for its Pioneering Cell Imaging Solution, the cellTRAY(R) Imaging System CT-2000 2Frost & Sullivan Recognizes Nanopoint for its Pioneering Cell Imaging Solution, the cellTRAY(R) Imaging System CT-2000 3Frost & Sullivan Recognizes Nanopoint for its Pioneering Cell Imaging Solution, the cellTRAY(R) Imaging System CT-2000 4Frost & Sullivan Recognizes Nanopoint for its Pioneering Cell Imaging Solution, the cellTRAY(R) Imaging System CT-2000 5
Recommended for use as a cell culture substratum at 0.1-0.2 mg/cm 2 or 5-10 μl/cm 2 . Optimal concentration depends on cell type as well as the application or research objectives. Type B...
... The Eclipse is a state-of-the-art separation ... Fractionation (AFFF) technique. The Eclipse integrates easily ... DAWN, miniDAWN Tristar, as well as the ... size and molar mass distributions of the ...
... for determining the absolute count of CD34+ ... peripheral blood samples, and leukapheresis samples. These ... cell count and a total CD45 (leucocyte) ... use in the BD Procount progenitor cell ...
... Protein A and, until recently, no readily available ... purification. Standard methods for IgM purification generally are ... for removing all of the major impurities present ... Pierce has developed an easy-to-use affinity matrix and ...
Biology Products: