Navigation Links
VTT and GE Healthcare developing novel biomarkers to predict Alzheimer's disease
Date:6/26/2012

Scientists from VTT Technical Research Centre of Finland in collaboration with the University of Eastern Finland have recently discovered a serum biochemical signature which predicts progression to Alzheimer's disease months or even years before the first symptoms of the disease occur. The goal of the new collaboration between VTT and GE Healthcare is to validate this biomarker in a large patient cohort as well as to discover novel biomarker candidates.

Alzheimer's disease (AD) is a growing challenge to the health care systems and economies of developed countries with millions of patients suffering from this disease and increasing numbers of new cases diagnosed annually with the increasing ageing of populations.

Early detection of prodromal AD is vital both for assessing the efficacy of potential AD therapeutic agents as well as new disease modifying therapies are most likely to be effective when initiated during the early stages of disease. The elucidation of early metabolic pathways associated with progression to Alzheimer's disease may also help in identifying new therapeutic avenues.

In 2010 GE Healthcare entered into "biosignatures initiative" alliance with Janssen Pharmaceutica N.V. (Janssen) to develop diagnostic biosignatures for pre-symptomatic identification of AD. As part of this programme, VTT will apply serum metabolite profiling to validate their recently discovered biochemical signature, as well as to discover novel biomarker candidates predictive of progression to AD.

VTT's research professor Matej Oreič said: "We are excited about the prospect of collaborating with GE Healthcare to accelerate its research programs and to further develop our biomarker towards a clinical assay applicable in healthcare setting. VTT has over the past years built unique metabolomics and systems biology platforms and acquired vast amount of knowledge on metabolic profiles and pathways in human health and disease, which allow us
'/>"/>

Contact: Sampo Sammalisto
sampo.sammalisto@vtt.fi
358-505-841-100
VTT Technical Research Centre of Finland
Source:Eurekalert

Page: 1 2

Related biology news :

1. BGI, GE Healthcare team up on pioneering stem cell science projects
2. Premier Healthcare Renews Supplier Agreement with Masimo
3. Early Bird Offers on Healthcare and Biotechnology Conferences, Save Up To 20% by Registering with Global Information
4. Bioethics for Beginners: 60 Cases and Cautions from the Moral Frontier of Healthcare
5. Boston Healthcare Associates Roundtable Explores Challenges and Opportunities Surrounding the Value of Big Data within the Life Sciences
6. Early Bird Discounts Available on International Healthcare and Biotechnology Conferences, Save Up To $600 with Global Information
7. Attendees Save Up To $800 on Boston-area Pharmaceutical and Healthcare Conferences, Early Bird Discounts Expiring April 27
8. Agricultural expert outlines path for developing nations to double food production, meet 2050 demand
9. Medbox Developing a Patent Pending Wall-Mounted Biometric Kiosk for Storage of Sensitive Medicine Samples and Supplies for Doctors Offices.
10. Research4Life greatly expands peer-reviewed research available to developing world
11. Family history of liver cancer increases risk of developing the disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/8/2015)... Calif. , May 8, 2015 Synaptics Inc. ... solutions, today announced that members of the executive management team ... Morgan 43rd Annual Technology, Media and Telecom Conference Date: ... Hotel in Boston, MA ... 27, 2015 Time: 2:45pm ET Location: The New York Palace ...
(Date:4/27/2015)... , Apr. 27, 2015 NXT-ID, Inc. ... biometric authentication company focused on the growing mobile commerce ... shipping to pre-order customers the first week of May, ... the month of May. Gino ... significant milestone for the company as Wocket® enters the ...
(Date:4/17/2015)... BURNABY, Canada , April 17, 2015 /PRNewswire/ ... projects, growing security concerns, and technological advancement to ... Arabia until 2020   ... " Saudi Arabia Biometric Systems Market Forecast &  Opportunities, 2020 ", biometric ... is projected to register growth at CAGR ...
Breaking Biology News(10 mins):Synaptics to Present at Upcoming Investor Conferences 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 2Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 3
... - With infections increasingly resistant to even the most ... Institute at Harbor-UCLA Medical Center (LA BioMed) report in ... clues they have uncovered in immune system molecules that ... Nannette Y. Yount present evidence that small proteins in ...
... prove a permanent turn on for some genes. Research published today ... why former smokers are still more susceptible to lung cancer than ... by Wan L Lam and Stephen Lam from the BC Cancer ... smokers, as well as from non-smokers who have never smoked. They ...
... AK The historic collaboration between leading scientists and ... for Health and the ,Global Environment at Harvard Medical ... continues this week with a trip to Alaska. A ... traveling together on August 25th to observe first- ,hand ...
Cached Biology News:Researchers discover new strategies for antibiotic resistance 2Smoking turns on genes -- permanently 2Scientist-evangelical Alaska expedition 2
(Date:5/28/2015)... Boston, MA (PRWEB) May 28, 2015 ... and director, James L. Sherley, M.D., Ph.D., will present ... cell medicine. In a conference talk, he will ... stem cell culture designs with computer simulation to produce ... stem cell number and quality over time in culture. ...
(Date:5/27/2015)... May 27, 2015  The Companion Diagnostics Deals ... and unprecedented access to the partnering deals and ... companies during 2014. Using these reports, ... the partnering activities of the past year. The ... partnering and alliances deals announced worldwide.The initial chapters ...
(Date:5/27/2015)... Research and Markets ( http://www.researchandmarkets.com/research/l633xp/molecular ... PharmaBiotech,s new report "Molecular Diagnostics - ... offering. This report describes and ... play an important role in practice of ... biological warfare in the 21st century. This ...
(Date:5/27/2015)... (PRWEB) May 27, 2015 The Academy of ... join in celebrating National Model Aviation Day. The third annual ... was created to celebrate the model aviation hobby nation-wide and ... all of its approximately 2,350 chartered clubs to celebrate the ... event in their communities. There will also be a local ...
Breaking Biology Technology:Asymmetrex Will Discuss the Importance of Adult Tissue Stem Cell Time with 3D Tissue Engineers at the 14th Annual World Preclinical Congress in Boston in June 2Asymmetrex Will Discuss the Importance of Adult Tissue Stem Cell Time with 3D Tissue Engineers at the 14th Annual World Preclinical Congress in Boston in June 3Companion Diagnostics Deals and Alliances of 2014 2Global Molecular Diagnostics Market 2015-2024 - Analysis of Key Technologies, Markets and Companies 2Global Molecular Diagnostics Market 2015-2024 - Analysis of Key Technologies, Markets and Companies 3Academy of Model Aeronautics Foundation to host National Model Aviation Day Motorcycle Rally and Family Fest in Muncie, IN 2Academy of Model Aeronautics Foundation to host National Model Aviation Day Motorcycle Rally and Family Fest in Muncie, IN 3
... FDA Submission for Removal of Clinical Hold, ... Bulletin Board: GNTA) announced that the Company has,received ... the European,Patent Office for its pipeline product, tesetaxel, ... of matter for the tesetaxel drug,substance and to ...
... Technology to Lexicon Targets, COPENHAGEN, June 10 ... Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX ) aimed,at ... for highly,validated drug targets., Under the terms ... will be applied to identify novel small molecule,lead ...
... Mass., June 9 Boston Scientific,Corporation (NYSE: ... Ratings,that it has revised its Rating Outlook on ... the Company,s long-term credit rating of,BB+., Fitch ... progress Boston,Scientific is making toward stabilizing its drug-eluting ...
Cached Biology Technology:Genta Receives Notice of Allowances for European Patents Related to Composition and Processes for Tesetaxel, a Leading Oral Taxane 2Genta Receives Notice of Allowances for European Patents Related to Composition and Processes for Tesetaxel, a Leading Oral Taxane 3Genta Receives Notice of Allowances for European Patents Related to Composition and Processes for Tesetaxel, a Leading Oral Taxane 4Nuevolution Announces Drug Discovery Alliance With Lexicon Pharmaceuticals 2Nuevolution Announces Drug Discovery Alliance With Lexicon Pharmaceuticals 3Boston Scientific Welcomes Revised Outlook From Fitch Ratings 2Boston Scientific Welcomes Revised Outlook From Fitch Ratings 3
...
... 48° Fixed Angle Polypropylene Rotor designed ... IEC Centra CL3/CL3R** and Centra-MP4/MP4R*. A ... operation. /MP4, ,EXCLUSIVE polypropylene rotor design ... be repeatedly autoclaved. Polypropylene rotors ...
... The Xcise is a powerful technology platform ... proteome analysis. High quality sample preparation ... user. , The Xcise is a powerful ... high throughput proteome analysis. It combines the ...
Request Info...
Biology Products: