Navigation Links
VAI researchers find long awaited key to creating drought resistant crops
Date:12/3/2009

.D. The lab began studying abscisic acid signaling in March this year because a proposed ABA receptor was reported to be a member of G-protein coupled receptors, a group of proteins that the lab studies. More than 50% of all drugs on the market target these proteins, but it has been extremely difficult to determine their atomic structure.

Xu's laboratory uses a technique known as X-ray crystallography to determine exactly how and why the drug compounds work in molecular detail, which can then help drug developers engineer more potent drugs that have fewer unwanted side effects.

Although it later resulted that the abscisic acid receptors were found to be members of another protein family, Xu's lab continued their studies on the newly identified ABA receptors. Their findings could help to develop crops that grow in drought, cold, salt water environments, and other harsh conditions, perhaps aiding in stemming or reversing food shortages around the world. Additionally, proteins central to ABA sensing are related to human proteins involved in cellular stress responses and may have implications for stress disorders in humans.

"Proteins with similarities to plant ABA receptors are also found in humans," said Xu. "Further studies in this area could reveal important implications for people with stress disorders."

The lab worked with specialists in plant biology at other institutions to validate the data, including the National Center for Plant Gene Research in Beijing, China, the Department of Botany and Plant Sciences at the University of California at Riverside, the Center for Plant Stress Genomics and Technology at the King Abdullah University of Science and Technology in Thuwal, Saudi Arabia, and the Department of Biochemistry at the Medical College of Wisconsin.

"A finding of this importance helps demonstrate how discoveries at the molecular level in plants can have profound implications for the diseases of humans." sa
'/>"/>

Contact: Joe GAvan
616-234-5390
Van Andel Research Institute
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UGA researchers lead team in discovery involving devastating freshwater fish parasite, Ich
2. Nervy research: Researchers take initial look at ion channels in a model system
3. Yerkes researchers create first transgenic prairie voles
4. North Pole wolf emails locations to researchers
5. Shape shifters: Researchers create new breed of antennas
6. Clemson researchers receive EPA grant to study carbon emission storage
7. Researchers discover biological basis of bacterial immune system
8. Researchers establish common seasonal pattern among bacterial communities in Arctic rivers
9. Racial disparity in colon cancer survival not easily explained, UAB researchers say
10. Researchers begin to decipher metabolism of sexual assault drug
11. Texas A&M Researchers Examine How Viruses Destroy Bacteria
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... of biomedical engineering at the University of Houston, ... and artificial organ development., "Introduction to Tissue Engineering: ... entering into the field of artificial organ development. ... engineering at UH, served as a series editor ... are other published books on the subject of ...
(Date:7/25/2014)... (NRG1) is a pleiotropic factor characterized by the ... of exons that confer to the protein deeply ... both the myelination occurring during development and the ... nerve: axon degeneration, axon regrowth, remyelination and target ... have discovered that the soluble NRG1 upregulation observed ...
(Date:7/25/2014)... girls reach puberty is influenced by ,imprinted genes,a subset of ... gene. This is the first evidence that imprinted genes ... of this study were published today in the journal ... menarche, is a marker for the timing of puberty in ... varies between girls, is an inherited trait, and is linked ...
Breaking Biology News(10 mins):University of Houston researcher publishes textbook on tissue engineering 2Could age of first period influence development of diseases in older women? 2
... MOConstructing a body is like building a houseif you compromise ... on a cellular level than in the case of epithelial ... from the gut to mammary glands. As long as epithelial ... business of building tissue barriers and constructing ducts goes smoothly. ...
... to the brain could be developed thanks to new research. ... able to regenerate protective sheaths around nerve fibres in the ... myelin, are critical for the quick transmission of nerve signals, ... with multiple sclerosis (MS). The study, by the Universities ...
... to assess the status of dozens of European fish stocks ... are being fished sustainably today and that, given time, those ... Cell Press journal Current Biology on July 18, ... European Union,s Common Fisheries Policy is failing, the researchers say. ...
Cached Biology News:A flip of the mitotic spindle has disastrous consequences for epithelial cells 2A flip of the mitotic spindle has disastrous consequences for epithelial cells 3A flip of the mitotic spindle has disastrous consequences for epithelial cells 4MS research could help repair damage affecting nerves 2European fish stocks poised for recovery 2
(Date:7/24/2014)... RIDGE, Tenn., July 24, 2014 -- A novel combination ... the Department of Energy,s Oak Ridge National Laboratory an ... for its unusual physical and electrochemical properties. , ... how oxygen affects the surface of a perovskite manganite, ... behavior. The new avenue to understand surface behavior could ...
(Date:7/24/2014)...  ECC West Africa, LLC (ECC) signed a contract ... College Hospital (UCH) Ibadan Board of Management for the ... construct, and operate and maintain a new, state-of-the-art Cancer ... the first of the 4-phase project, ECC will conduct ... UCH Ibadan intends to finance and develop the Cancer ...
(Date:7/24/2014)... Distinguished Professor of Engineering at the University of ... solve problems in energy engineering, environmental sustainability and ... zeolites, porous rock with a well-defined, crystalline structure. ... so precisely decided that zeolites can separate molecules ... an angstrom (one-tenth of a nanometer), making them ...
(Date:7/24/2014)... 2014 Your cell phone may ... lithium-ion battery storage capacity. , New research indicates ... model created at Lawrence Livermore National Laboratory ... how carbon components will perform as electrodes. , ... urgent need for higher-performance batteries. Several key characteristics ...
Breaking Biology Technology:ORNL study reveals new characteristics of complex oxide surfaces 2ECC Signs a Contract for the Finance, Design, and Construction of a Premier Cancer Institute in Ibadan, Nigeria 2University of Delaware researcher describes new approach for creating organic zeolites 2Getting More Life out of Lithium-ion Batteries 2
... , , , , , ... Kits and Ser/Thr Kinase , Kit provide fast and ... serine/threonine kinases. LiquiChip 10-Cytokine Kits enable simultaneous , multiplex ... The LiquiChip Ser/Thr Kinase Kit enables highly sensitive assay of kinases , ...
... , The proven activated dendrimer for transfection , of a ... and benefits , , Fast ... cell lines , Transfection in the presence of serum (see figure ... , High transient and stable transfection efficiencies , ...
... , For purification of endotoxin-free ultrapure , plasmid or cosmid DNA , ... , Less than 0.1 EU/g plasmid DNA , ... Greater than 90% recovery of plasmid DNA , Fast and simple ... , , * Actual yields depend on plasmid copy number, size ...
Cached Biology Technology:LiquiChip Kits for bead-based cytokine and kinase assays 2LiquiChip Kits for bead-based cytokine and kinase assays 3SuperFect Transfection Reagent 2SuperFect Transfection Reagent 3EndoFree Plasmid Kits 2EndoFree Plasmid Kits 3EndoFree Plasmid Kits 4