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University of Tennessee professor releases weight management product

How would you like to experience the effects of running three miles or staving off type two diabetes without making drastic changes in your lifestyle? With nutrition supplements developed by a professor at the University of Tennessee, Knoxville, you can.

NuSirt Sciences Inc., founded by Professor Emeritus of nutrition Michael Zemel, has released a weight management product called NuShape, and a product for healthy blood sugar called NuControl.

A video about the products can be viewed by visiting

"NuSirt Sciences seeks to use our understanding of how molecules function and relate to one another and combine it with our knowledge of metabolic pathways," said Zemel.

"This can uncover metabolic activities in safe, natural products that prevent metabolic diseases such as obesity, metabolic syndrome, diabetes and cardiovascular disease."

NuShape is an all-natural weight management product taken in pill form. When taken twice a day, it burns up to 300 calories a day by increasing fat oxidation. Clinical randomized studies show that when combined with modest caloric restriction (exercise or diet), participants nearly doubled both fat loss and weight loss over a three-month period. For a six-month period, they maintained 60 to 70 percent of weight loss or fat loss. The product also was shown to help participants retain lean muscle mass, which is typically lost during dieting. Results of the study can be found in Nutrients by visiting

But the pill does need a little help.

"Let's be clear; this is not magic," said Zemel. "Instead, this is a product that will work with you. We ask that you add about 15 minutes a day of moderate physical exercise over and above what you already do. That should burn about 100 calories. With NuShape, you will burn an extra 400 calories a day."

Zemel also stressed that customers who take more than two pills a day will only be wasting moneynot burning more calories.

NuShape consists of the amino acid leucine, found in foods like fish, soybeans, beef and lentils, and vitamin B6, found in foods such as bread, meat, poultry, eggs and bananas. The vitamin inhibits fat storage. When combined with leucine, it stimulates fat oxidation in the muscle. The specific ratio of the two allows for fat to be transferred to the muscle to be burned.

The second supplement, NuControl, helps promote healthy blood sugar levels. It works by converging on the same metabolic pathway as the anti-aging nutrient resveratrol. Zemel explained the challenge with resveratrol is that you need an exorbitant amount to reap the benefits. By performing molecular, cellular and animal studies, as well as human clinical trials, Zemel discovered a design that unlocks resveratrol's benefits by adding other nutrients, which lowers the needed concentration.

"Insulin is, of course, a very important hormone, but you would like to operate at low levels of insulin," said Zemel. "As you gain weight, you become less insulin sensitive, and it takes more insulin to produce normal blood sugar control. NuControl helps address this issue by promoting the body's natural ability to metabolize sugar more effectively. In fact, initial in vivo research showed the NuControl blend of leucine and resveratrol improved insulin sensitivity levels in mice by 40 to 50 percent."

Zemel said he aims to shape the future of pharmaceuticals through natural therapies that are based on sound science and are just as effective as traditional solutions, with no side effects. These two products are the first in a line to be released. The next product will tackle cardiovascular health.

Contact: Whitney Heins
University of Tennessee at Knoxville

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