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University of Houston researcher an author of multi-institutional genetic study of ovarian cancer
Date:7/8/2011

na Genome Analyzer early. It gave us the opportunity to rapidly sequence hundreds of tumors to discover a valuable collection of potential tumor suppressor microRNAs for ovarian and a spectrum of other cancers," she said. "Because ovarian cancer has been particularly refractory to all current therapies and it remains the fifth- leading cause of cancer death in women and the most common gynecological malignancy, it is particularly exciting to see this project come to fruition.

Gunaratne said the next step for her team is to further develop the tumor-suppressor microRNAs discovered from this project and others in preclinical studies. The ultimate goal is to develop treatment therapies that can wipe out cancer-causing cells at very low doses of chemotherapy by exploiting the body's own silencing molecules such as microRNAs.


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Contact: Laura Tolley
ljtolley@uh.edu
713-743-0778
University of Houston
Source:Eurekalert

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