Navigation Links
University of Houston researcher an author of multi-institutional genetic study of ovarian cancer
Date:7/8/2011

A University of Houston researcher is an author on a landmark multi-institutional genetic study of the most aggressive and common form of ovarian cancer that is published in the current issue of the scientific journal Nature. Ovarian cancer is the fifth-leading cause of cancer death in women in the United States.

The genome sequencing study, which was conducted by The Cancer Genome Atlas (TCGA) research network, provides the first comprehensive genetic overview of ovarian cancer, showing the changes that turn normal ovarian cells into deadly tumors that are highly resistant to chemotherapy. Researchers discovered that the ovarian cancer genome is overwhelmingly characterized by mutations in one gene and few other common mutations, but it also has frequent structural changes, indicating that those mutations are significant to the cancer's development.

Preethi Gunaratne, an assistant professor in UH's department of biology and biochemistry, is an author of the study, which is the largest such project to date conducted by TCGA, a network of institutions funded by the National Cancer Institute and the National Human Genome Research Institute of the National Institute of Health. Two other Houston institutions, Baylor College of Medicine and MD Anderson Cancer Center, also participated in the study, along with a number of others across the nation.

The findings could lead to better treatments for ovarian cancer, which claims the lives of nearly 14,000 women in the U.S. every year and is often not diagnosed until it's in an advanced stage.

"Ovarian cancer has been very difficult to treat. It has been very resistant to even the most advanced chemotherapy cocktails," Gunaratne said.

Gunaratne, along with Dr. Neil Hayes at the Lineberger Comprehensive Cancer Center at the University of North Carolina and Dr. Douglas Levine at the Memorial Sloan Kettering Cancer Center (MSKCCC), spearheaded the analysis of microRNAs, a class of tiny genetic m
'/>"/>

Contact: Laura Tolley
ljtolley@uh.edu
713-743-0778
University of Houston
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Rice University establishes National Corrosion Center
2. Case Western Reserve University researchers track Chernobyl fallout
3. Case Western Reserve University project ties soil conservation and river management together
4. Brown University and Women & Infants Hospital expand national childrens study to Bristol County
5. NIH selects Case Western Reserve University to participate in National Childrens Study
6. US Senate confirms Clemson University engineering Dean Esin Gulari to National Science Board
7. University professor stresses links between US Navy sonar and whale strandings
8. Scent on demand: Hebrew University scientists enhance the scent of flowers
9. University success at national engineering awards
10. University of Leicester professor adds new perspective to rainforest debate
11. Providing toilets, safe water is top route to reducing world poverty: UN University
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... is paving the way for a breakthrough that ... troops exposed to poisonous chemicalsparticularly those in pesticides ... the current issue of the journal ChemBioChem ... are compounds commonly used in pesticides and warfare ... School of Engineering Associate Professor of Chemical and ...
(Date:7/30/2014)... potential effects of climate change on the world,s ... wrong factors, according to a new paper by ... University of Queensland, and other organizations. The authors ... missing the point when it comes to climate ... change scientists focus on the "direct" threats of ...
(Date:7/30/2014)... pleased to announce its new relationship with the International ... CINP will partner to publish International Journal of ... journal. , Alan Frazer, Editor-in-Chief of IJNP ... of OUP will further facilitate the goal for the ... leading journals within neuropsychopharmacology. The conversion of the ...
Breaking Biology News(10 mins):Engineering a protein to prevent brain damage from toxic agents 2Conservation scientists asking wrong questions on climate change impacts on wildlife 2OUP to partner with the International College of Neuropsychopharmacology 2
... doesn,t stop at borders. Mexico, the U.S., and Canada ... and resource problems. In an effort to promote active ... of Geoscience and the Institute of Geology of the ... Mxico; UNAM) are hosting the 108th meeting of GSA,s ...
... (NIMML) research team at Virginia Tech has discovered important ... (CLA) in treating Crohn,s disease, a form of inflammatory ... acid found in meat and dairy products known for ... collaboration with the Division of Gastroenterology and Hepathology at ...
... MD FASEB MARC (Maximizing Access to Research Careers) ... Experimental Biology 2012 (EB 2012) meeting in San Diego, ... meant to promote the entry of underrepresented minority students, ... science community and to encourage the participation of young ...
Cached Biology News:Geological Society of America Cordilleran section meets in the heart of Mexico 2Geological Society of America Cordilleran section meets in the heart of Mexico 3Geological Society of America Cordilleran section meets in the heart of Mexico 4Researchers discover novel therapy for Crohn's disease 2MARC travel awards announced for EB 2012 2MARC travel awards announced for EB 2012 3MARC travel awards announced for EB 2012 4MARC travel awards announced for EB 2012 5
(Date:7/31/2014)... Chicago, IL (PRWEB) July 31, 2014 ... wave of automation across the U.S., increasing unemployment, ... middle class. It is a Catch 22—we ... internationally, but this means fewer jobs,” says economist ... the just-released Pollina Corporate Top 10 Pro-Business States ...
(Date:7/31/2014)... Boston’s Adult Stem Cell Technology Center, ... adult stem cell biotechnologies. Currently the company holds ... additional patent applications currently under examination by the U.S. ... two of the most vexing problems in adult stem ... cells are difficult to identify; and they have been ...
(Date:7/30/2014)... 30, 2014 W. R. Grace ... of the REVELERIS® Prep purification system , ... chromatographers, and other researchers to perform both flash ... unit. , With the REVELERIS® Prep purification system, ... chromatography modes with a simple touch of the ...
(Date:7/30/2014)... 30, 2014  Replikins Ltd. today released new data ... virus. Before the current outbreaks, the mean Ebola Reston ... acids) between 1995 and 2002 was 1.1; the mean ... and sixteen-fold in 2013, thus predicting the current outbreaks ... has been shown to be able to predict outbreaks ...
Breaking Biology Technology:ITRA Global Affiliate’s Pollina Corporate Top 10 Pro-Business States Minimize the Impact of Automation on Middle Class and Unemployment 2ITRA Global Affiliate’s Pollina Corporate Top 10 Pro-Business States Minimize the Impact of Automation on Middle Class and Unemployment 3ITRA Global Affiliate’s Pollina Corporate Top 10 Pro-Business States Minimize the Impact of Automation on Middle Class and Unemployment 4The Adult Stem Cell Technology Center, LLC Launches A Marketing Campaign To License Adult Stem Cell Biotechnologies 2The Adult Stem Cell Technology Center, LLC Launches A Marketing Campaign To License Adult Stem Cell Biotechnologies 3Grace Launches New REVELERIS® Prep Purification System 2
... 11 Nikon Instruments Inc. has,provided an in-kind ... of Agriculture, Forestry and Life Sciences biological,sciences department ... will,be the first of its kind in the ... systems Nikon Instruments Inc. has installed,anywhere in the ...
... China, Nov. 11 /Xinhua-PRNewswire-FirstCall/ --,China Biologic Products, Inc. ... of the leading plasma-based pharmaceutical companies in the,People,s ... will host a,conference call at 10:00 a.m. EST ... quarter 2008 results., Hosting the call will ...
... testing using dried blood spot,specimens, BASKING RIDGE, N.J., ... Hooper Holmes (Amex: HH ), today announced,certification of ... Program (NGSP)., Heritage Labs uses two blood testing ... and the other for testing dried blood,spots (DBS), both ...
Cached Biology Technology:Nikon Instruments Provides Donation to Help Clemson University Start New Core Microscopy Facility 2Nikon Instruments Provides Donation to Help Clemson University Start New Core Microscopy Facility 3China Biologic Products Announces Third Quarter 2008 Results Conference Call 2Heritage Labs Announces A1c Test Certification Milestone 2Heritage Labs Announces A1c Test Certification Milestone 3
... Error-free cloning of BAC (100+kb), fosmid ... Greater insert stability than any othe BAC ... for high yields and easy recombinant DNA ... or transcription-free (pSMART VC) vectors for the ...
... cloning of BAC (100+kb), fosmid (40kb), and ... stability than any othe BAC vector. On ... yields and easy recombinant DNA purification. Available ... (pSMART VC) vectors for the highest insert ...
Mouse Exodus 2 - 12kDa...
TGF-beta 2 MAb (Clone 8607)...
Biology Products: