Navigation Links
University of Arizona scientist shares in discovery of microbe filaments' power
Date:4/18/2008

Researchers from The University of Arizona and Columbia University have discovered that tiny filaments on bacteria can bundle together and pull with forces far stronger than experts had previously thought possible.

The team of researchers, including Magdalene Maggie So, a member of the BIO5 Institute and the department of immunobiology in the UA College of Medicine, studied Type IV pili or filaments on the surface of Neisseria gonorrhoeae, the bacterium that causes the infectious disease gonorrhea. The research results help them understand the role that Type IV pili play in initiating a variety of infectious diseases including tuberculosis and how retracting pili allow bacteria to crawl and to exchange genes with each other.

When a bundle of Type IV pili retracts, it pulls with a force in the nanoNewton range, which is 10 times the force of a single retracting filament. The study demonstrates the power and cooperative nature of the nanomotors that cause Type IV pili to retract.

The motor that causes these filaments to pull is one of the strongest nanomotors known in biology, So said.

In previous studies, the same group of investigators measured single filament retraction forces in the 50 to 100 picoNewton range. This force allows the bacterium to move an object 10,000 times its own body weight. Retraction forces from a bundle are roughly 10 times higher, allowing the bacterium to move objects 100,000 times its body weight.

Pilus retraction forces are an important factor in how N. gonorrhoeae starts an infection. So, who has studied these microbes for more than 20 years, says N. gonorrhoeae communicates with a human cell by pulling on it. These pulling forces perturb the normal circuitry of the cell. As a result, the infected cell is fooled into lowering its defenses against the infecting microbe.

So said that the team of investigators came up with a new method to measure the tremendous forces applied by
'/>"/>

Contact: Deborah Daun
ddaun@email.arizona.edu
520-626-2059
University of Arizona
Source:Eurekalert

Page: 1 2

Related biology news :

1. Flowers fragrance diminished by air pollution, University of Virginia study indicates
2. Pitt and University of Chicago researchers uncover process behind heart muscle contraction
3. Yale Universitys Strobel recognized for work on RNA
4. Womens health-related scientific findings presented by University of Pittsburgh researchers
5. Researchers at Stockholm University awarded the Descartes prize
6. Policing cells demand ID to tell friend from foe, say University of Pennsylvania cell engineers
7. Antarcticas coldest, darkest season draws Montana State University researchers
8. University of Colorado at Boulder awarded $1 million for biofuels research
9. Viruses evolve to play by host rules, according to University of Pennsylvania researchers
10. New whitepaper offers options for university implementation of NIH policy
11. Electronic structure of DNA revealed for 1st time by Hebrew University and collaborating researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... National Institute of Standards and Technology (NIST), working ... improved technique for analyzing biological cells and tissues ... NIST technique is an advanced form of the ... delivers signals that are 10,000 times stronger than ... stronger than obtained from comparable "coherent Raman" instruments, ...
(Date:7/22/2014)... Rochelle, NY -- Stem cells offer much promise for ... approaches stem cell survival is poor, limiting their effectiveness. ... the survival and optimize their therapeutic function after transplantation, ... Open Access , a peer-reviewed journal from Mary Ann ... the BioResearch Open Access website . ...
(Date:7/22/2014)... July 22, 2014 BGI Tech Solutions Co., ... world,s largest genomics organization, announced today the global ... service based on Complete Genomics, industry-leading platform. This ... SNP validation, and is available at reduced prices ... highly regarded in the industry for providing proprietary ...
Breaking Biology News(10 mins):Enhanced NIST instrument enables high-speed chemical imaging of tissues 2Enhanced NIST instrument enables high-speed chemical imaging of tissues 3BGI Tech launches human whole exome sequencing service on complete genomics' advanced platform 2
... developing bipolar disorder depends in part on the combined, small ... brain, none of which is powerful enough to cause the ... the enzyme produced by one of these genes could lead ... was conducted by scientists at the National Institutes of Health's ...
... their effects on fat development, researchers have discovered that ... mice without some of the side effects attributed to ... harmine, was first isolated more than 150 years ago ... around the world, the team reports in the May ...
... it express who we are, but is it really possible to ... to that question seems to be related to fashion and glamour, ... Mexico and the Buck Institute in the USA, were able to ... In biology, the capacity to establish the function of a molecule, ...
Cached Biology News:Genetic roots of bipolar disorder revealed by first genome-wide study of illness 2Genetic roots of bipolar disorder revealed by first genome-wide study of illness 3Fat screen delivers plant-derived chemical with antidiabetic effects 2
(Date:7/23/2014)... 23, 2014 With the ability to record ... for more than 15 minutes, Fastec Imaging has brought the ... high speed imaging. “Finally, a high speed camera that can ... in our everyday lives.” proclaims Matt Kearney, VP of Sales ... been to demystify and simplify the traditionally complicated workflow of ...
(Date:7/23/2014)... 23, 2014 a2z Inc. announces that ... App, AACC Pathfinder, in its 2014 Annual Meeting ... meeting is planned for July 29-31, 2014 in Chicago, ... be to connect with global leaders in clinical chemistry, ... other areas of breaking science in laboratory medicine. , ...
(Date:7/23/2014)... MA (PRWEB) July 23, 2014 ... of innovative and comprehensive consultancy and pharma training ... Excellence and Safety (ACRES) , a non-profit integrating ... to build and maintain a global system for ... alliance collaboration to improve the expertise of industry ...
(Date:7/22/2014)... July 22, 2014 The Board of Directors of ... has declared a quarterly dividend of 54.5 cents per common ... on September 9, 2014. The indicated annual dividend rate is ... BD is a leading medical technology company that partners with ... pressing and evolving health needs. Our innovative solutions are focused ...
Breaking Biology Technology:Fastec Imaging Introduces the First High Speed Camcorder 2Fastec Imaging Introduces the First High Speed Camcorder 3AACC Enhances Attendee Experience at Its 2014 Annual Meeting & Clinical Lab Expo with a2z-Powered ChirpE Photo Booth and Mobile App 2AACC Enhances Attendee Experience at Its 2014 Annual Meeting & Clinical Lab Expo with a2z-Powered ChirpE Photo Booth and Mobile App 3Astra Nova and ACRES Partner on Quality and Access of Training for Research Professionals 2Astra Nova and ACRES Partner on Quality and Access of Training for Research Professionals 3
... This release is available in French . Physicists ... energy involved in adding electrons to semi-conductor nanocrystals, also known ... and other areas of science. Dr. Peter Grtter, McGill,s Associate ... that his research team has developed a cantilever force sensor ...
... EDMONTON , May 11 ... company focused on developing medical device,products for use ... it has,received regulatory concurrence from the United States ... product, Occlusin(R) 500 Artificial,Embolization Device (OCL 500) in ...
... ORLANDO, Fla. , May 11 GeneLink, Inc. (OTC Bulletin ... quarter ended March 31, 2010 . , , ... , , , ... Quarterly operating loss reduced by 14% over Q4 2009 Comparable quarter gross profit improvement ...
Cached Biology Technology:Quantum move toward next generation computing 2IMBiotechnologies Receives FDA Clearance to Market Occlusin(R) 500 Biodegradable Microspheres in the U.S. 2IMBiotechnologies Receives FDA Clearance to Market Occlusin(R) 500 Biodegradable Microspheres in the U.S. 3GeneLink Reports First Quarter Gains 2
Tissue culture grade....
Tris-Hepes kit of BG-163 & BG-165 (order number BG-166)...
... ideal for both radioactive and nonradioactive labeling ... Provides five pre-mixed nucleotide solutions for flexibility ... 8 cpm/g control DNA using [-32P]-dCTP ... performance of the system Labels 1 ...
Activating Agents, 7-azabenzotriazol-1-yloxy-tris-(pyrrolidino)phosphonium hexafluorophosphate...
Biology Products: