Navigation Links
University of Arizona scientist shares in discovery of microbe filaments' power
Date:4/18/2008

Researchers from The University of Arizona and Columbia University have discovered that tiny filaments on bacteria can bundle together and pull with forces far stronger than experts had previously thought possible.

The team of researchers, including Magdalene Maggie So, a member of the BIO5 Institute and the department of immunobiology in the UA College of Medicine, studied Type IV pili or filaments on the surface of Neisseria gonorrhoeae, the bacterium that causes the infectious disease gonorrhea. The research results help them understand the role that Type IV pili play in initiating a variety of infectious diseases including tuberculosis and how retracting pili allow bacteria to crawl and to exchange genes with each other.

When a bundle of Type IV pili retracts, it pulls with a force in the nanoNewton range, which is 10 times the force of a single retracting filament. The study demonstrates the power and cooperative nature of the nanomotors that cause Type IV pili to retract.

The motor that causes these filaments to pull is one of the strongest nanomotors known in biology, So said.

In previous studies, the same group of investigators measured single filament retraction forces in the 50 to 100 picoNewton range. This force allows the bacterium to move an object 10,000 times its own body weight. Retraction forces from a bundle are roughly 10 times higher, allowing the bacterium to move objects 100,000 times its body weight.

Pilus retraction forces are an important factor in how N. gonorrhoeae starts an infection. So, who has studied these microbes for more than 20 years, says N. gonorrhoeae communicates with a human cell by pulling on it. These pulling forces perturb the normal circuitry of the cell. As a result, the infected cell is fooled into lowering its defenses against the infecting microbe.

So said that the team of investigators came up with a new method to measure the tremendous forces applied by
'/>"/>

Contact: Deborah Daun
ddaun@email.arizona.edu
520-626-2059
University of Arizona
Source:Eurekalert

Page: 1 2

Related biology news :

1. Flowers fragrance diminished by air pollution, University of Virginia study indicates
2. Pitt and University of Chicago researchers uncover process behind heart muscle contraction
3. Yale Universitys Strobel recognized for work on RNA
4. Womens health-related scientific findings presented by University of Pittsburgh researchers
5. Researchers at Stockholm University awarded the Descartes prize
6. Policing cells demand ID to tell friend from foe, say University of Pennsylvania cell engineers
7. Antarcticas coldest, darkest season draws Montana State University researchers
8. University of Colorado at Boulder awarded $1 million for biofuels research
9. Viruses evolve to play by host rules, according to University of Pennsylvania researchers
10. New whitepaper offers options for university implementation of NIH policy
11. Electronic structure of DNA revealed for 1st time by Hebrew University and collaborating researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/10/2015)... , April 10, 2015 ... addition of the "Security Competitive Profiles - NEC" ... http://photos.prnewswire.com/prnh/20130307/600769) , NEC will continue to supply ... to the market, with a company focus on the ... anticipated. Winning opportunities in the ...
(Date:4/6/2015)... Conn. , Apr. 6, 2015 NXT-ID, ... "Company"), a biometric authentication company focused on the ... has filed provisional patent 62/143028 for ... COMMUNICATIONS AND ENERGY TRANSFER  NXT-ID introduces a ... payments. This patent surrounds the use of miniature ...
(Date:4/2/2015)... Sweden , April 2, 2015 ... for Q1 2015 attributed to somewhat higher than 125 ... in the year-end report 2014 that revenues for Q1 ... that the company reported for Q4 2014. The operating ... to be negative. The complete interim report will as ...
Breaking Biology News(10 mins):NEC Security Competitive Profile 2015 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 3NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 4Fingerprint Cards Revises Revenues for Q1 2015 2
... , This release is available in ... the Tulane University School of Medicine, in New ... major component of black seed oil ( Nigella ... aggressive prostate cancer (PCa) cell lines, in vitro. ...
... widely known for precisely positioning and sculpting various organs ... that could be useful for understanding the explosive growth ... are being born with genital and urinary tract malformations. ... Communications , researchers at the University of Florida say ...
... The International Institute for Species Exploration at Arizona State University ... calendar year. The list for 2009 was published to coincide ... of Carl Linnaeus. It contains only two new plant species, ... Journal of the Linnean Society . Nepenthes ...
Cached Biology News:Thymoquinone induced oxidative stress targets highly aggressive prostate cancers 2Sluggish cell division may help explain genital defects 2Sluggish cell division may help explain genital defects 3Sluggish cell division may help explain genital defects 4Rare carnivorous plant on top 10 list of newly discovered species 2
(Date:4/28/2015)... Boston, MA (PRWEB) April 28, 2015 ... the science of the little-known and incurable disease, ... awarded $485,840 in grants to new projects in the ... and children around the world. , The FSH Society’s ... proposals for the grants. They awarded monies to projects ...
(Date:4/28/2015)... (PRWEB) April 28, 2015 CargoSense, ... company focused on supply chain logistics, today announced ... its seed round, bringing total investment proceeds to ... early stage venture capital firms IrishAngels and Middleburg ... Innovative Technology, also participated in the round. ...
(Date:4/28/2015)... Pittsburgh, PA (PRWEB) April 28, 2015 ... its participation in the upcoming Labroots virtual ... May 13-14, 2015. The theme of this ... genomics topics such as RNAi, Next-generation sequencing, ... epigenetics, mapping, exomes, genomic medicine, human Genome ...
(Date:4/28/2015)... April 28, 2015 Showcasing continued ... a relationship marketing company that provides scientifically advanced, ... of the Direct Selling Association (DSA) by the ... minimum one-year review period, the DSA confirmed that ... and expectations of the association: to ensure that ...
Breaking Biology Technology:FSH Society Awards $485,000 in Grants for Research Dedicated to FSH Muscular Dystrophy 2FSH Society Awards $485,000 in Grants for Research Dedicated to FSH Muscular Dystrophy 3FSH Society Awards $485,000 in Grants for Research Dedicated to FSH Muscular Dystrophy 4CargoSense Completes Seed Round Offering By Raising $2.5 Million 2CargoSense Completes Seed Round Offering By Raising $2.5 Million 3CargoSense Completes Seed Round Offering By Raising $2.5 Million 4Pittcon Announces Plans to Exhibit at the Annual Labroots Genetics and Genomics Virtual Event 2Pittcon Announces Plans to Exhibit at the Annual Labroots Genetics and Genomics Virtual Event 3Nerium International Receives Direct Selling Association Membership 2Nerium International Receives Direct Selling Association Membership 3
... of our nation,s long-term clean-energy future, but the technology ... Japan,s recent Fukushima disaster. Indeed, many nations have called ... are operating safely. In the United States, ... percent of the electricity from emission-free sources, including renewable ...
... Mediabrands, IPG Media Lab and Affectiva today announced, ... results of the first annual Neuromarketing Awards. Utilizing ... record and measure viewers, tacit, non-verbal response to ... features are established and are then measured and ...
... ,   The randomised, ... efficacy and safety of,the monoclonal antibody rituximab (RTX) ... that in patients with,severe AAV a single course ... period of 18 months proved to be as ...
Cached Biology Technology:Berkeley scientists pioneer nanoscale nuclear materials testing capability 2The IPG Media Lab and Affectiva Announce Winners of First Annual Neuromarketing Awards 2The IPG Media Lab and Affectiva Announce Winners of First Annual Neuromarketing Awards 3ERA-EDTA Congress 2011: Late Breaking Clinical Trials I 2