Navigation Links
Uncultured bacteria found in amniotic fluids of women who experience preterm births
Date:1/5/2009

CLEVELANDResearchers from Case Western Reserve University and Yale University have made a significant advancement in understanding the cause behind why some pregnant women suffer from inflammations in the inner womb without any signs of an infection.

Using gene-cloning techniques, researchers discovered that approximately 60 percent of the bacteria present in women with intra-amniotic inflammations were missed by traditional culture testing considered the gold standard for finding bacterial infections.

The findings were reported in the January issue of the Journal of Clinical Microbiology.

For the first time, the researchers identified a comprehensive list of microbial species in intra-amniotic infections by using new DNA methods to track down the presence of bacteria. To increase their accuracy the investigators used a combination of analyses including proteomics results of amniotic fluid and histological analysis of the placenta to corroborate the infection and inflammation.

Intra-amniotic inflammation is known to set off spontaneous births of preterm babies at less than 32 weeks, said Yiping Han, associate professor of dental medicine at Case Western Reserve University and lead investigator on the study of 46 women of which 44 experienced preterm births. Han has previously done a number of research projects examining the link between oral bacteria and preterm birth.

In the present study, bacteria levels from the amniotic fluids of pregnant women with signs or symptoms of preterm births were compared to those from a control group of 16 women without such manifestations and who delivered at term. The amniotic fluid of the control group came from amniocenteses for genetic screenings or analyses to check fetal lung maturity and showed no signs of bacteria even by DNA methods.

"Because culturing is not finding all bacteria present in the amniotic fluid, this calls for new detection methods," Han
'/>"/>

Contact: Susan Griffith
susan.griffith@case.edu
216-368-1004
Case Western Reserve University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Shuttle brings space-grown strep bacteria back for study
2. The worlds oldest bacteria
3. Bacteria from sponges make new pharmaceuticals
4. Boston University biomedical engineers find chink in bacterias armor
5. University of Leicester scientists discover technique to help friendly bacteria
6. Spaceflight shown to alter ability of bacteria to cause disease
7. A tiny pinch from a z-ring helps bacteria cells divide
8. Legionnaires bacterial proteins work together to survive
9. Scripps research team blocks bacterial communication system to prevent deadly staph infections
10. NSF awards Stevens team $1 million for research on smart, bacteria-repellent nanohydrogels
11. Chemical compound present in detergents produce bacteria alterations in agricultural soils
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... 20, 2014 C-Labs LLC, a leading provider ... Things (IoT), today announced the appointment of John ... Previously a strategic advisor to the firm, Mr. Traynor ... Traynor is based out of the C-Labs office in ... Chris Muench , Chief Executive Officer. ...
(Date:11/18/2014)...  The Secure Identity & Biometrics Association (SIBA) ... the formation of The Airport Entry and Exit ... and Biometric Entry and Exit Solutions Framework for ... from BORDERPOL, the international non-profit organization that works ... regarding border security, traveler and migration systems. ...
(Date:11/18/2014)... , Nov. 17, 2014 The Parenteral Drug ... U.S. regulatory agencies will speak and at least seven more ... Conference at the Omni Shoreham Hotel in Washington ... once again to have significant support from the regulatory agencies ... Europe in our effort to help advance ...
Breaking Biology News(10 mins):C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2
... Virginia Key, FL March 14, 2011 -- The University ... proud to announce that Dr. Peter Mumby is the 2011 ... honors. Mumby, a British marine ecologist and professor at Australia,s ... Award. His goal is to understand the benefits and limitations ...
... common parasitic infection can vary greatly from person to person, ... three strains of the cat-borne parasite Toxoplasma gondii ... invades. Past research suggests that the parasite, estimated to ... psychotic symptoms and schizophrenia in genetically predisposed people. The ...
... premier plant biology journals published by the American Society of ... The Plant Cell -- completed their migration to HighWire ... HighWire, the online hosting platform for more than 1,000 scholarly ... a standards-based hosting solution that is putting ASPB,s journals at ...
Cached Biology News:Peter Mumby to receive prestigious 2011 Rosenstiel Award from the University of Miami 2Toxoplasmosis: The strain explains severity of infection 2ASPB journals migrate to new Web platform 2
(Date:11/22/2014)... 2014 RURO, Inc., a leading ... released Limfinity® version 5.1.4. , RURO’s deployment teams ... than ever in RURO’s 8 year history. Many ... enhancement. Limfinity® version 5.1.4 is the perfect example ... bug fixes! , Limfinity® 5.1.4 release highlights – ...
(Date:11/22/2014)... 2014   , ... Officer zu KLOX    ... Financial Officer bestellt    KLOX ist ... jüngst zugelassenen Behandlungssystems zur Wundheilung zu beginnen    , ... ist sehr erfreut, die folgenden personellen Veränderungen anzukündigen: ...
(Date:11/21/2014)... Author Matthew J. Pallamary’s second short story ... published as a tribute to his mentor Ray ... Story” category of the 2014 USA Best Book ... USA Book News, said this year’s contest yielded over ... & Schuster, Penguin, John Wiley & Sons, Houghton Mifflin ...
(Date:11/21/2014)... 2014 Why did Stephen Hawking become ... so instantly recognizable? Why have they become icons to ... author Hilton Ratcliffe seeks out the answers to those ... to do with science. In " Stephen Hawking Smoked ... 21, 2014), Ratcliffe puts it plainly: , “It ...
Breaking Biology Technology:RURO Announces Limfinity® version 5.1.4 2KLOX Technologies meldet Neubesetzung von Führungspositionen 2KLOX Technologies meldet Neubesetzung von Führungspositionen 3KLOX Technologies meldet Neubesetzung von Führungspositionen 4KLOX Technologies meldet Neubesetzung von Führungspositionen 5Mystic Ink 's Short Story Collection “A Short Walk to the Other Side” Honoring Ray Bradbury Praised As Award-Winning Finalist In USA Best Book Awards 2Mystic Ink 's Short Story Collection “A Short Walk to the Other Side” Honoring Ray Bradbury Praised As Award-Winning Finalist In USA Best Book Awards 3Mystic Ink 's Short Story Collection “A Short Walk to the Other Side” Honoring Ray Bradbury Praised As Award-Winning Finalist In USA Best Book Awards 4“Stephen Hawking Smoked My Socks” Sparks Controversy in Science World 2“Stephen Hawking Smoked My Socks” Sparks Controversy in Science World 3“Stephen Hawking Smoked My Socks” Sparks Controversy in Science World 4
... that want the benefits of cutting-edge health care possibilities ... sub-populations need to foster the new science at ... by Nature Publishing Group. , In a special six-paper ... (NRG), researchers from the McLaughlin-Rotman Centre for Global Health ...
... a significant milestone for the growing open source clincial trials ... towards the needs of regulated industry sponsored clinical trials. ... ... 2008 -- Akaza Research announces the availability of OpenClinica 2.5, ...
... ABBOTT PARK, Ill., Sept. 19 Abbott (NYSE:,ABT) will ... 2008, before the market opens., The announcement will ... call at 8 a.m. Central time (9 a.m. Eastern), ... at, http://www.abbottinvestor.com . An archived edition of the call ...
Cached Biology Technology:As personalized, genomic medicine takes off, four developing countries show the way for others 2As personalized, genomic medicine takes off, four developing countries show the way for others 3As personalized, genomic medicine takes off, four developing countries show the way for others 4As personalized, genomic medicine takes off, four developing countries show the way for others 5As personalized, genomic medicine takes off, four developing countries show the way for others 6As personalized, genomic medicine takes off, four developing countries show the way for others 7Akaza Research Releases New Version of OpenClinica Electronic Data Capture (EDC) Software; Targets Industry Clinical Trials 2Akaza Research Releases New Version of OpenClinica Electronic Data Capture (EDC) Software; Targets Industry Clinical Trials 3
... channels for automated gigaseal patch clamping. ... voltage-gated ion channels, such as hERG and ... The four pipette heads afford more efficient ... drug discovery. The glass-coated tunnels of ...
... plating in just seconds , No ... flaming, More uniform spreading and more colonies, ... bottle for spreading 100 plates or single-use tubes ... way to spread cells on multiple plates simultaneously ...
... culture or fermentation is the ability to ... make rapid adjustments in response to changes ... provide immediate analysis of key nutrients, metabolites, ... media. BioProfile analyzers are fully automated, multi-test ...
... acid synthetic peptide whose sequence is from rat SCAMP 5. ... C - N(217) - Q - P - Q - T ... P - N - Y - T - Y - S ... and control experiments with the polyclonal antibody that reacts with this ...
Biology Products: