Buchanan will discuss lessons learned from studying risk of type 2 diabetes in Hispanic women who previously had diabetes during pregnancy (gestational diabetes) and whether early treatment can help preserve beta cell mass to prevent progression to type 2 diabetes. The symposium will take place on Saturday, June 6 (Session: Beta Cell Mass Adaptive Responses to Metabolic Demand; How Do Beta Cells Respond to Increased Demand in People? Lessons from Pregnancy, Gestational Diabetes, and the Evolution of Type 2 Diabetes).
Casey Donovan, Ph.D., professor of kinesiology and biology, will discuss his research on the role of the brain and the portal vein in sensing and regulating low blood sugar.
Building on his research that determined the portal vein connecting the pancreas and liver has glucose sensors that alert the body to low blood sugar, Donovan will talk about different ways the portal vein sensors may connect to or signal the brain to respond to hypoglycemia. The symposium will take place on Sunday, June 7 (Session: Beyond the Hypothalamus Other Sites Involved in Sensing and Responding to Recurrent Hypoglycemia; Peripheral vs. Central Sensors Importance of Rate of Glucose Drop).
Richard Watanabe, Ph.D., associate professor of preventive medicine, will discuss genome-wide association studies for type 2 diabetes and related traits focusing on genetic variants in genes involving the pancreatic beta cell.
Such genetic changes may result in diabetes. Next steps in genetic research, follow-up on initial findings, and the relation of certain genes to beta cells will be discussed. The symposium will take place on Monday, June 8 (Session: Diabetes Maps to the Beta Cell: Where Do We Go from Genome-Wide Association Studies? Overview of Genome-Wide Association Studies, Implications for the Beta Cell and the Melatonin Receptor).
|Contact: Leslie Ridgeway|
University of Southern California