Navigation Links
USC researchers discover genetic mutation causing excessive hair growth
Date:6/3/2011

Los Angeles, Calif., June 2, 2011Researchers in the Keck School of Medicine of the University of Southern California (USC), together with scientists in Beijing, China, have discovered a chromosomal mutation responsible for a very rare condition in which people grow excess hair all over their bodies. Investigators hope the finding ultimately will lead to new treatments for this and less severe forms of excessive hair growth as well as baldness.

The study, "X-linked congenital hypertrichosis syndrome is associated with interchromosomal insertions mediated by a human-specific palindrome near SOX3," will appear in the June 2, 2011 issue of the American Journal of Human Genetics.

Pragna Patel, professor in the Keck School, the USC Institute for Genetic Medicine, and the Herman Ostrow School of Dentistry of USC, is a co-investigator of the study, and Sunju Choi, a research associate in Patel's lab, is a co-first author. The principal investigator is Xue Zhang, professor and chair of medical genetics at the Peking Union Medical College.

The initial discovery of the mutation came from Zhang's lab, which examined the condition, known as CGH, in a Chinese family. Researchers there worked with Choi to confirm the finding in a Mexican family that Patel first began studying in 1993. Males with this disorder have hair covering their entire face including their eyelids and their upper body, while females have thick patches of hair on their bodies.

"In 1995, we traced the approximate location of the mutation responsible for CGH to a section of the X chromosome in the Mexican family," said Patel, whose laboratory focuses on understanding the genetic basis of inherited diseases. "We sequenced nearly 100 genes but could not find any mutations. Then recently, Xue Zhang and his colleagues in Beijing were able to pinpoint the exact location, discovering that there was an insertion of chromosome 5 into the X chromosome in the Chinese fami
'/>"/>

Contact: Leslie Ridgeway
leslie.ridgeway@usc.edu
323-442-2823
University of Southern California
Source:Eurekalert

Page: 1 2

Related biology news :

1. Eating dirt can be good for the belly, researchers find
2. Caltech researchers build largest biochemical circuit out of small synthetic DNA molecules
3. UNH researchers receive grant for pioneering carbon cycle model
4. Penn researchers help nanoscale engineers choose self-assembling proteins
5. Researchers from the Viikki Biocenter discover how plants control the formation of wood cells
6. Researchers solve mammoth evolutionary puzzle: The woollies werent picky, happy to interbreed
7. What is a laboratory mouse? Jackson, UNC researchers reveal the details
8. MDC researchers discover key molecule for stem cell pluripotency
9. Researchers track the secret lives of feral and free-roaming house cats
10. UTHealth researchers find diabetics at higher risk of tuberculosis infection
11. UT Southwestern researchers find protein breakdown contributes to pelvic organ prolapse
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2015)... 2015 According to a ... (Hardware, Software, Services), by Applications (Surveillance (Airborne, Maritime, ... End-Users (Military & Defense & Commercial) - Global ... Market is expected to grow from $7252.0 Million ... a Compound Annual Growth Rate (CAGR) of 6.6%. ...
(Date:5/21/2015)... 2015 The Sync Project™ , a ... health, today announced a collaborative partnership with Berklee,s ... center on collaboration on original research, joint course development ... the collaboration, The Sync Project and BerkleeICE are exploring ... in the 2015-2016 academic year.  The ...
(Date:5/20/2015)... , May 20, 2015 ... ) has announced the addition of ... Global Iris Recognition Market"  report to ... ,This research service analyses trends in ... government and commercial sectors, globally. Despite ...
Breaking Biology News(10 mins):Thermal Imaging Market Worth $9,998.9 Million by 2020 2Thermal Imaging Market Worth $9,998.9 Million by 2020 3Thermal Imaging Market Worth $9,998.9 Million by 2020 4The Sync Project Announces Partnership with Berklee College of Music's Institute for Creative Entrepreneurship 2The Sync Project Announces Partnership with Berklee College of Music's Institute for Creative Entrepreneurship 3Global Iris Recognition Market Report 2015 - 5-Year Opportunity Analysis 2
... release is available in Spanish . , AgroAtlas ... of 100 crops; 640 species of crop diseases, pests, and ... neighboring countries. Downloadable maps and geographic information system (GIS) software ... relating major wheat production areas to concentrations of Russian wheat ...
... neurosurgery to bar code readers, lasers have been used in ... the late 1950,s. Now, with the work being done in ... way to use lasers to study the splicing of pre-messenger ... advanced organisms, including human life. This process of splicing is ...
... research led by UC Davis and Stanford University found that ... biologists had thought. The study, published today in the ... estimate of white shark numbers in the northeast Pacific Ocean. ... known white-shark populations (the others are in Australia/New Zealand and ...
Cached Biology News:USDA and Russian scientists develop high-tech crop map 2Brandeis researchers use lasers, custom microscope to show gene splicing process in real time 2Brandeis researchers use lasers, custom microscope to show gene splicing process in real time 3First census finds surprisingly few white sharks off California 2
(Date:5/20/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/x4b7kw/top_technologies ) has ... HW_Technical Insights" report to their offering. ... in the Health and Wellness sector and has identified ... impact in the year 2015. The research service provides ... and wellness technologies that are anticipated to have the ...
(Date:5/20/2015)... Research and Markets ( http://www.researchandmarkets.com/research/qfxkcq/global_cell ) ... Therapy Market Outlook 2020 " report to their ... and regenerative medicine is expected to have huge marketing ... help in the growth of deregulated organs. Several therapeutic ... unable to form new tissue or sometimes organ transplant ...
(Date:5/20/2015)... global genotyping market is expected to grow at a ... to 2020 to reach $17.0billion in 2020. Genotyping tests ... process and to provide personalized therapy, factors that are ... key manufacturers to offer advanced and innovative products for ... market data tables & 37 figures spread through 200 ...
(Date:5/20/2015)... 20, 2015 Agricultural firm H.J. Baker ... its acquisition of Tiger-Sul. Since the purchase of ... Canada) in May 2005, H.J. Baker has leveraged the ... into a comprehensive portfolio of product offerings and solutions ... Baker and the innovation of Tiger-Sul, transforming the company ...
Breaking Biology Technology:Top Technologies in the Health and Wellness Industry 2015 2Global Cell Therapy Market Outlook 2015-2020 - 262 Cell Therapies & 13 Marketed Cell Therapies 2Global Cell Therapy Market Outlook 2015-2020 - 262 Cell Therapies & 13 Marketed Cell Therapies 3Genotyping Market Growing at 22.3% CAGR to 2020: Research Based on Technology, Applications, Opportunities, Challenges and Key Players. 2Genotyping Market Growing at 22.3% CAGR to 2020: Research Based on Technology, Applications, Opportunities, Challenges and Key Players. 3Genotyping Market Growing at 22.3% CAGR to 2020: Research Based on Technology, Applications, Opportunities, Challenges and Key Players. 4Genotyping Market Growing at 22.3% CAGR to 2020: Research Based on Technology, Applications, Opportunities, Challenges and Key Players. 5Agricultural Firm H.J. Baker & Bro., Inc., Celebrates 10 Years Since Acquisition Of Tiger-Sul 2Agricultural Firm H.J. Baker & Bro., Inc., Celebrates 10 Years Since Acquisition Of Tiger-Sul 3
... WORCESTER, Mass., Jan. 25, 2011 Generex Biotechnology Corporation ... GNBT ) today announced that it entered into ... January 24, 2011.  The investors have agreed to purchase ... common stock and warrants to purchase shares of common ...
... NEW YORK, Jan. 25, 2011 Reportlinker.com ... is available in its catalogue: ... Strategic Implications of Emerging Reimbursement, Technological and ... http://www.reportlinker.com/p0365288/Future-US-In-Vitro-Diagnostics-Market-Strategic-Implications-of-Emerging-Reimbursement-Technological-and-Market-Trends-through-2018.html How ...
... 2011 /PRNewswire-Asia-FirstCall/ -- 3SBio Inc. (Nasdaq: ... China-based biotechnology company focused on researching, developing, manufacturing ... has received official notification from China,s State Food ... for a TPIAO label extension for the treatment ...
Cached Biology Technology:Generex Announces $3.0 Million Capital Investment 2Generex Announces $3.0 Million Capital Investment 3Generex Announces $3.0 Million Capital Investment 4Reportlinker Adds Future US In Vitro Diagnostics Market: Strategic Implications of Emerging Reimbursement, Technological and Market Trends Through 2018 23SBio Inc. Receives SFDA Approval for TPIAO Label Extension for the Treatment of ITP 23SBio Inc. Receives SFDA Approval for TPIAO Label Extension for the Treatment of ITP 33SBio Inc. Receives SFDA Approval for TPIAO Label Extension for the Treatment of ITP 4
IkappaB-alpha (112B2) Mouse mAb...
...
Dopamine D2 and D3 receptor, human and possibly mouse. AB1502 detects 40 ng of dopamine receptor peptide by ELISA. AB1502 is not neutralizing....
Rabbit polyclonal to SpUlp2 ( Abpromise for all tested applications). Antigen: Synthetic peptide: SNNERQSLSSGSND, corresponding to amino acids 622-635 of Schizosaccharomyces pombe SpUlp2...
Biology Products: