Navigation Links
UCSF receives $4.5M to study value of gene sequencing in newborns
Date:9/5/2013

UC San Francisco will receive $4.5 million over the next five years for a pilot project to assess whether large-scale gene sequencing aimed at detecting disorders and conditions can and should become a routine part of newborn testing.

The study is one of four projects launched today by the National Institutes of Health to identify the accuracy and feasibility of providing genetic sequencing as part of, or instead of, the current newborn screening that relies on biochemical changes in the blood. It also will assess what additional information would be useful to have at birth and the ethics and public interest in having such tests performed.

Genomic sequencing has the potential to diagnose a vast array of disorders and conditions at the very start of life, said Alan E. Guttmacher, MD, director of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (ICHD), which is jointly funding the studies. But the ability to decipher an individuals genetic code rapidly also brings with it a host of clinical and ethical issues, which is why it is important that this program explores the trio of technical, clinical, and ethical aspects of genomics research in the newborn period.

The pilots are a core element of the emerging field of precision medicine, which aims to harness vast amounts of genetic and health data to create predictive, preventive and precise care for patients on an international scale. Doing so has the potential to transform medicine, but there are many logistical and ethical hurdles to resolve along the way.

The UCSF team, which also includes bioinformatics experts at UC Berkeley and the Buck Institute for Research on Aging, will study the potential of sequencing the exome the roughly 2 percent of DNA that represents genes which code for proteins as a method of newborn screening. The research will look at the exome
'/>"/>

Contact: Kristen Bole
kristen.bole@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. In search for a vaccine, IU biologist receives $2.3 million to explore chlamydia genomics
2. Renowned geneticist R. Rodney Howell receives ACMG Foundation Lifetime Achievement Award
3. UF receives $1 million from Keck Foundation to study mechanisms of inherited disease
4. Gladstone scientist Warner C. Greene receives Washington University School of Medicine Alumni Award
5. Carnegies Wolf B. Frommer receives Bogorad Award for Excellence in Plant Biology
6. UC Riverside plant cell biologist receives top scientific honor
7. UC Riverside receives grant for global health and development research
8. Washington University receives $8 million to lead international childhood malnutrition effort
9. SRI Sarnoffs Iris on the Move® N-Glance™ Identification System Receives Lenel Factory Certification
10. SF State biology department receives $1.5 million to support science teaching
11. Dr. Karen Lloyd receives WHOIs Holger W. Jannasch Visiting Scholar Award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... DURHAM, N.C. In a cost-effectiveness analysis of commercial ... the drug Qsymia showed the best value for the ... loss, but was also the most expensive option tested, ... Graduate Medical School. , The findings, published in the ... important information on the health and weight-loss benefits per ...
(Date:7/22/2014)... NEW YORK, NY -- As part of a multinational, ... at Mount Sinai have helped identify over 100 locations ... developing schizophrenia, in the largest genomic study published on ... The findings, published online in Nature , point ... and could lead to new approaches to treating the ...
(Date:7/22/2014)... have adapted to New York City,s human behaviour, allowing ... than their fellow squirrels in the woods. , Dr ... & Agriculture, led the study that proved eastern grey ... environments and prevent unnecessary responses when humans acted in ... , "As we rapidly increase the spread of ...
Breaking Biology News(10 mins):Study compares cost-effectiveness of weight-loss programs and drugs 2Study compares cost-effectiveness of weight-loss programs and drugs 3Mount Sinai scientists and international team shed new light on schizophrenia 2Mount Sinai scientists and international team shed new light on schizophrenia 3New York squirrels are nuts about city life 2
... natural coal deposits in the Gulf of Alaska are ... Exxon Valdez tanker catastrophe. This clearly disproves the theory ... environmental damage. PAH pollutants were blamed for the continuing ... Then a dispute erupted over the origins of these ...
... Pasadena, Calif.In a finding that sheds new light on ... the California Institute of Technology (Caltech) have pinpointed the ... The discovery, described in the August 30 ... offer insight into autism and other disorders where social ...
... and some amphibians possess a unique sensory capability in ... to "touch" objects in their surroundings without direct physical ... van Hermmen and his team in the physics department ... basis for this sensory system. What they discover might ...
Cached Biology News:Bioavailable contaminants come from the Exxon Valdez oil catastrophe 2Caltech neuroscientists find brain region responsible for our sense of personal space 2Caltech neuroscientists find brain region responsible for our sense of personal space 3Caltech neuroscientists find brain region responsible for our sense of personal space 4Mathematical keys to a sixth sense -- the lateral-line system 2Mathematical keys to a sixth sense -- the lateral-line system 3Mathematical keys to a sixth sense -- the lateral-line system 4
(Date:7/23/2014)... With the ability to record continuously at ... than 15 minutes, Fastec Imaging has brought the same ease-of-use ... imaging. “Finally, a high speed camera that can be used ... everyday lives.” proclaims Matt Kearney, VP of Sales for Fastec ... demystify and simplify the traditionally complicated workflow of a high ...
(Date:7/22/2014)... Web) July 21, 2014 (PRWEB) July 23, 2014 ... Biomaterials, at Rutgers University. , The goal ... ideas across the full spectrum of scientists working ... research and development topics that represent the most ... been programmed to:,     Provide faculty ...
(Date:7/22/2014)... lecturer in mechanical engineering at the University of Texas ... by the North Texas section of the American Society ... 130,000 members in 158 countries who develop engineering standards ... engineering community, benefiting the world. , ASME recognized Baughn ... Engineers honors banquet. Baughn retired as an engineering fellow ...
(Date:7/22/2014)... Lake, Wisconsin (PRWEB) July 22, 2014 ... be in attendance at the 2014 NCSL International ... Booth #423 will feature CONDEC pressure instrumentation, ... style weights, and the new, customized sets, Essential ... ago to promote cooperative efforts in solving the ...
Breaking Biology Technology:Fastec Imaging Introduces the First High Speed Camcorder 2Fastec Imaging Introduces the First High Speed Camcorder 3The 2014 NJ Symposium on Biomaterials Science Earns Society for Biomaterials Endorsement 2UT Dallas professor receives Engineer of the Year award 2Rice Lake Weighing Systems Showcases Metrology Solutions for the 2014 NCSL International Workshop & Symposium 2
... , , , JEFFERSON, N.C., ... give people more confidence to go to work in a pandemic ... products the company developed for the bird flu influenza A subtype ... for the bird flu (H5N1), which never became contagious. The Next ...
... , , SEATTLE, Aug. ... Stephen R. Murray, M.D., Ph.D. as Vice President of ... and protocols at Omeros, and currently is leading the ... include OMS103HP, the Company,s lead candidate being evaluated in ...
... , ... pleased to announce that SK Life Science, Inc. (SKLSI), has licensed Pristima for its Research ... ... a world leader in toxicology and pathology data management solutions and the developer of Pristima™ ...
Cached Biology Technology:Next Safety Releases Advanced Respirator for Infectious Diseases 2Next Safety Releases Advanced Respirator for Infectious Diseases 3Omeros Appoints New Vice President of Clinical Development 2SK Life Sciences has Licensed Pristima 2
Evolutionarily conserved signaling intermediate in Toll pathway...
Phosphatidylinositol transfer protein beta isoform (PtdIns transfer protein beta) (PtdInsTP) (PI-TP-beta). [Source:Uniprot/SWISSPROT;Acc:P48739] Antigen: Recombinant Protein Epitope Signature Tag...
Mouse monoclonal [88B] to nicotinic Acetylcholine Receptor ( Abpromise for all tested applications)....
PPIF Antibody...
Biology Products: