Navigation Links
UCSB researchers perform pioneering research on Type 2 diabetes
Date:1/4/2013

(Santa Barbara, Calif.) While legions of medical researchers have been looking to understand the genetic basis of disease and how mutations may affect human health, a group of biomedical researchers at UC Santa Barbara is studying the metabolism of cells and their surrounding tissue, to ferret out ways in which certain diseases begin. This approach, which includes computer modeling, can be applied to Type 2 diabetes, autoimmune diseases, and neurodegenerative diseases, among others.

Scientists at UCSB have published groundbreaking results of a study of Type 2 diabetes that point to changes in cellular metabolism as the triggering factor for the disease, rather than genetic predisposition. Type 2 diabetes is a chronic condition in which blood sugar or glucose levels are high. It affects a large and growing segment of the human population, especially among the obese. The team of scientists expects the discovery to become a basis for efforts to prevent and cure this disease.

The current work is based on a previous major finding by UCSB's Jamey Marth, who determined the identity of the molecular building blocks needed in constructing the four types of macromolecules of all cells when he was based at the Howard Hughes Medical Institute in La Jolla in 2008. These include the innate, genetic macromolecules, such as nucleic acids (DNA and RNA) and their encoded proteins, and the acquired metabolic macromolecules known as glycans and lipids. Marth is a professor in the Department of Molecular, Cellular, and Developmental Biology and the Biomolecular Science and Engineering Program; and holds the John Carbon Chair in Biochemistry and Molecular Biology and the Duncan and Suzanne Mellichamp Chair in Systems Biology. He is also a professor with the Sanford-Burnham Medical Research Institute in La Jolla.

"By studying the four types of components that make up the cell, we can, for the first time, begin to understand what causes many of the common g
'/>"/>

Contact: Gail Gallessich
gail.g@ia.ucsb.edu
805-893-7220
University of California - Santa Barbara
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Researchers develop tool to evaluate genome sequencing method
2. Jackson Laboratory researchers provide definitive proof for receptors role in synapse development
3. Researchers discover genetic basis for eczema, new avenue to therapies
4. Thomas Jefferson University researchers discover new pathways that drive metastatic prostate cancer
5. Carin Görings remains identified by researchers at Uppsala University
6. CNIO researchers develop new databases for understanding the human genome
7. 3 Johns Hopkins researchers named AAAS Fellows
8. Leibniz Prizes 2013: DFG honors 11 outstanding researchers
9. Researchers and company from Luxembourg awarded a grant from Michael J. Fox Foundation
10. Researchers find new culprit in castration-resistant prostate cancer
11. ASU researchers propose new way to look at the dawn of life
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UCSB researchers perform pioneering research on Type 2 diabetes
(Date:9/17/2014)... social behavior by studying nonhuman mammals and primates, but ... their unusually large brains relative to their body size ... environment---not merely in a large population of cooperating creatures, ... setting of alliances and competitors. The same is true ... social carnivores, like hyenas and lions. , A new ...
(Date:9/16/2014)... women in Australia is increased by lower socioeconomic ... September) in BJOG: An International Journal of ... high standards of living; however, existing research has ... indigenous and non indigenous Australians. , This case-control ... socioeconomic position on severe maternal morbidities associated with ...
(Date:9/16/2014)... "molecular brakes" that time the generation of important cells ... cells" translate sound waves into electrical signals that are ... If the arrangement of the cells is disordered, hearing ... will be published in The Journal of Neuroscience ... Hey2 act as brakes to prevent hair cell generation ...
Breaking Biology News(10 mins):Being social: Learning from the behavior of birds 2New study examines the impact of socioeconomic position & maternal morbidity in Australia 2New study examines the impact of socioeconomic position & maternal morbidity in Australia 3Hey1 and Hey2 ensure inner ear 'hair cells' are made at the right time, in the right place 2
... Journal of Animal Science , meat scientists report that ... at the USDA-ARS, Roman L. Hruska US Meat Animal Research ... muscle (LM) tenderness and other meat quality traits between different ... The pigs used in this study came from one ...
... Researchers from North Carolina State University have developed a ... approaches and can be used to create technologies with ... lithography can be used to manufacture chips for use ... as proteins or genetic material associated with specific medical ...
... top wheat experts today reported a breakthrough in their ability ... rapidly mutating wheat pathogen called stem rust that threatens wheat ... by farmers and scientists from fields and laboratories, the creators ... 42 million hectares of wheat in 27 developing countries in ...
Cached Biology News:Chilling methods could change meat tenderness 2Researchers develop new, less expensive nanolithography technique 2Researchers launch new 'Rust-Tracker' to monitor deadly wheat fungus in 27 nations 2Researchers launch new 'Rust-Tracker' to monitor deadly wheat fungus in 27 nations 3Researchers launch new 'Rust-Tracker' to monitor deadly wheat fungus in 27 nations 4Researchers launch new 'Rust-Tracker' to monitor deadly wheat fungus in 27 nations 5Researchers launch new 'Rust-Tracker' to monitor deadly wheat fungus in 27 nations 6
(Date:9/17/2014)... WA , Sept. 17, 2014 /PRNewswire/ - Oncothyreon ... it intends to offer and sell shares of its ... separate but concurrent underwritten public offerings.  The Series A ... of Oncothyreon Common Stock, provided that conversion will be ... affiliates would beneficially own more than 4.99% of the ...
(Date:9/17/2014)... A biodegradable polymer can be ... bacteria, fungi, and algae into smaller units (monomers) ... compounds, carbon dioxide, and humus in a specified ... improved costs, biodegradable polymers are proving to be ... conventional polymers. Primary factors that are responsible for ...
(Date:9/17/2014)... Intarcia Therapeutics, Inc. today announced the presentation ... cost and predictability of non-adherence in type 2 diabetes ... the European Association for the Study of Diabetes (EASD). ... Ph.D., of Analysis Group, Inc. presented data from the ... to characterize the prevalence of non-adherence and serial non-adherence, ...
(Date:9/17/2014)... , Sept. 17, 2014 RXi ... biotechnology company focused on discovering, developing and commercializing ... RNA-targeted technologies, today announced that it has been granted ... Trademark Office on its unique delivery system for ... to phagocytic cells for the treatment of diseases ...
Breaking Biology Technology:Oncothyreon Announces Proposed Public Offerings 2Growing Demand for Eco-Friendly Products Drives the Global Biodegradable Polymers Market, According to New Report by Global Industry Analysts, Inc. 2Growing Demand for Eco-Friendly Products Drives the Global Biodegradable Polymers Market, According to New Report by Global Industry Analysts, Inc. 3Intarcia Reveals New Insights At EASD Meeting Characterizing The Burden Of Poor Control And Non-Adherence To Anti-Diabetic Therapies 2Intarcia Reveals New Insights At EASD Meeting Characterizing The Burden Of Poor Control And Non-Adherence To Anti-Diabetic Therapies 3Intarcia Reveals New Insights At EASD Meeting Characterizing The Burden Of Poor Control And Non-Adherence To Anti-Diabetic Therapies 4Intarcia Reveals New Insights At EASD Meeting Characterizing The Burden Of Poor Control And Non-Adherence To Anti-Diabetic Therapies 5RXi Pharmaceuticals Strengthens Intellectual Property Portfolio 2RXi Pharmaceuticals Strengthens Intellectual Property Portfolio 3RXi Pharmaceuticals Strengthens Intellectual Property Portfolio 4
... , , ... , ... for culturing cells in a BioFlo ,110 benchtop fermentor/bioreactor system. ... and control modules to,enable growth of a wide variety of cultures, ...
... Microscale on-membrane PMF analysis can be ... function of a chemical printer (Refer to AXIMA Application 14, 17). ... chemical printer enables MS analysis with high mass accuracy ( , ... separated by 2-dimensional electrophoresis were transferred to a PVDF membrane for ...
... Achieving Ultra Fast Liquid Chromatography ... , Prominence UFLC has ... this respect, we are successful,in demonstrating high speed and separation performance,without ... with other fast,LC systems., Smaller ...
Cached Biology Technology:CHO Cell Culture Application Using a BioFlo 110 Benchtop Bioreactor 2CHO Cell Culture Application Using a BioFlo 110 Benchtop Bioreactor 3CHO Cell Culture Application Using a BioFlo 110 Benchtop Bioreactor 4Direct On-Membrane MS/MS Analysis using the Chemical Printer (CHIP-1000) and AXIMA-QIT 2Prominence UFLC 2Prominence UFLC 3Prominence UFLC 4Prominence UFLC 5Prominence UFLC 6Prominence UFLC 7Prominence UFLC 8
... Includes gene gun unit, 5 O-rings, 5 ... tool, 9 V battery The Helios gene ... rapid and direct gene transfer into a range ... adjustable low-pressure helium pulse to sweep DNA- or ...
Mouse polyclonal antibody to PRDM2 - PR domain containing 2, with ZNF domain...
Intestinal Epithelium Differentiation Environment...
... [pTyr 209/ pSer 211 ] affinity isolated ... Dulbecco's phosphate buffered saline (without Mg 2+ ... mg/ml BSA (IgG and protease free) and 0.05% ... the region of mouse Hck that contains tyrosine ...
Biology Products: