Navigation Links
UCLA research may help scientists understand what causes pregnancy complications
Date:11/27/2013

Dr. Hanna Mikkola and researchers at UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have identified a specific type of cell and a related cell communication pathway that are key to the successful growth of a healthy placenta. The findings could greatly bolster our knowledge about the potential causes of complications during pregnancy.

Specifically, the findings could help scientists clarify the particular order in which progenitor cells grow in the placenta, which would allow researchers to track fetal development and identify complications. Progenitor cells are cells that develop into other cells and that initiate growth of the placenta.

The study was led by Mikkola, associate professor of molecular, cell, and developmental biology, and Dr. Masaya Ueno, a UCLA postdoctoral fellow. It was published online by the scientific journal Developmental Cell on Nov. 25 and will appear later in the journal's print edition.

The placenta is the organ that forms inside the uterus during pregnancy and enables oxygen and nutrients to reach the fetus, but little is understood about the biological mechanisms and cellular processes responsible for this interface. Studying mouse models, Mikkola and her colleagues tracked individual cells in the placenta to determine which cells and which cell communication routes, or signaling pathways, were responsible for the healthy development of the placenta.

The UCLA team was the first to identify the cells that form the placenta: Epcamhi labyrinth trophoblast progenitors, or LaTP cells, can become the various cells necessary to form a specific tissue, in this case the placenta.

Mikkola and her colleagues also found a signaling pathway that consists of hepatocyte growth factor and its receptor, c-Met. The researchers found that this signaling pathway was required for the placenta to keep making LaTP cells. Production of LaTP cells, in turn, conti
'/>"/>

Contact: Shaun Mason
smason@mednet.ucla.edu
310-206-2805
University of California - Los Angeles
Source:Eurekalert

Page: 1 2

Related biology news :

1. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
2. Research reveals first evidence of hunting by prehistoric Ohioans
3. Diabetes Research Institute develops oxygen-generating biomaterial
4. APS issues new policy requiring identification of sex or gender in reporting scientific research
5. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
6. Study jointly led by UCSB researcher supports theory of extraterrestrial impact
7. U of Alberta researcher steps closer to understand autoimmune diseases
8. Research on flavanols and procyanidins provides new insights into how these phytonutrients may positively impact human health
9. A project to research biological and chemical aspects of microalgae to fuel approach
10. Scripps Research discoveries lead to newly approved drug for infant respiratory distress syndrome
11. Researchers attempt to solve problems of antibiotic resistance and bee deaths in one
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2015)... Fla. , June 23, 2015 /PRNewswire/ ... management and authentication solutions, today announced enhanced functionality ... multi-factor authentication solution.  The enhancements build on ... of the DigitalPersona Altus platform and provide ... compatibility. In today,s environment of ...
(Date:6/18/2015)... Conn. , June 18, 2015 NXT-ID, Inc. ... authentication company focused on the growing mobile commerce market announces ... a featured segment on "Money on the Mark", scheduled to ... City June 20 th . ... will be from 7:00 to 8:00pm EST. NXT-ID, Inc.,s CEO ...
(Date:6/17/2015)... Germany , June 17, 2015 ... Standard: QIA) today launched new Investigator ® STR assay ... the United States . The new genetic ... key genomic markers (short tandem repeats or STRs) for DNA ... evaluate the quality of DNA in each sample, a novel ...
Breaking Biology News(10 mins):Crossmatch Releases Enhanced DigitalPersona Altus Advanced Authentication Functionality 2NXT-ID, Inc.'s CEO Gino Pereira Talks About the Wocket Smart Wallet on WABC Radio, New York City, June 20th 2NXT-ID, Inc.'s CEO Gino Pereira Talks About the Wocket Smart Wallet on WABC Radio, New York City, June 20th 3QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 2QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 3QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 4QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 5
... Mich. Picture a pretzel factory production line, with conveyer belts ... to be cooked. Now imagine what would happen if ... blob onto the conveyor, misshapen, and sticking fast to the dough ... And if that mess could no longer be conveyed into the ...
... struggle first observed in a species of North American ... European common lizard. The two species are separated by ... they share behavioral and reproductive details right down to ... research published in the November issue of American Naturalist ...
... Researchers at the University of Warwick have devised a ... warped fingerprints in just a few seconds. Previous ... on a finger print and laboriously match them against ... consider the entire detailed pattern of each print and ...
Cached Biology News:Botched production of insulin molecule may lead to diabetes 2Botched production of insulin molecule may lead to diabetes 3Botched production of insulin molecule may lead to diabetes 4Three-way mating game of North American lizard found in distant European relative 2Three-way mating game of North American lizard found in distant European relative 3Three-way mating game of North American lizard found in distant European relative 4New technology identifies warped fingerprints at warp speed 2
(Date:6/30/2015)... 30, 2015  Juniper Pharmaceuticals, Inc. (Nasdaq: JNP ... therapeutics that address unmet medical needs in women,s ... will present at the Cantor Fitzgerald Inaugural ... 2015Time: , 4:45 PM EDTLocation: , Le Parker ... , www.juniperpharma.com, under  ,Investor, or  click ...
(Date:6/30/2015)... ... June 30, 2015 , ... Noblis, Inc., ... announced in a paper published this week in the scientific journal Viruses ( ... diagnostic techniques currently used to detect the Ebola virus. Noblis worked with the ...
(Date:6/30/2015)...  Custom Computer Specialists, Inc. ("Custom"), a leading healthcare ... sponsors of the Primary Care Development Corporation,s ("PCDC") Corporate ... their support of PCDC,s mission to expand access to ... founding in 1993, PCDC has been a key force ... financed over 100 completed primary care projects, valued at ...
(Date:6/30/2015)... ... 2015 , ... Smarter Alloys today announced a final round ... allows orthodontists to simultaneously apply different forces to different teeth. The additional case ... about taking SmartArch one step closer to commercial availability for orthodontists and dentists,” ...
Breaking Biology Technology:Juniper Pharmaceuticals to Present at Cantor Fitzgerald Inaugural Healthcare Conference on July 8, 2015 2Noblis and Government Scientists Identify New Genomic Signatures of Ebola Using Whole Genomic Sequencing and Innovative BioVelocity Analytics Tool 2Noblis and Government Scientists Identify New Genomic Signatures of Ebola Using Whole Genomic Sequencing and Innovative BioVelocity Analytics Tool 3Noblis and Government Scientists Identify New Genomic Signatures of Ebola Using Whole Genomic Sequencing and Innovative BioVelocity Analytics Tool 4Custom Computer Specialists Announces Sponsorship Of The Primary Care Development Corporation's Corporate Circle 2New case studies for SmartArch orthodontic archwire paves way to product launch later this year 2
... the midst of a transition from imitator to innovator in ... of barriers and opportunities facing that country,s health biotech industry. ... the McLaughlin-Rotman Centre for Global Health (MRC), says South America,s ... capacity to emerge as a major global player. It ...
... GPRO ) announced today that the Company will present ... Medical Technology,Conference on Wednesday, June 11, 2008 at approximately ... is scheduled to be webcast,live and may be accessed ... website at http://www.gen-probe.com . The webcast will be,available ...
... 6 Bioheart, Inc. (Nasdaq:,BHRT) will host its 2008 ... Chispa Restaurant, located at 11500 NW 41st Street in ... Interested parties may listen to the Bioheart, Inc. ... or (706) 643-0580,(international). To listen to the Annual Meeting ...
Cached Biology Technology:Brazil's biotech firms: From imitators to innovators in health-related products 2Brazil's biotech firms: From imitators to innovators in health-related products 3Brazil's biotech firms: From imitators to innovators in health-related products 4Brazil's biotech firms: From imitators to innovators in health-related products 5Brazil's biotech firms: From imitators to innovators in health-related products 6Gen-Probe to Webcast Presentation at Seventh Annual Needham Biotechnology and Medical Technology Conference 2Bioheart, Inc. to Host Annual Meeting of Shareholders on Wednesday, July 30, 2008 2
... of seven reduced, denatured proteins (equine myoglobin, ... muscle GAPDH, bovine muscle actin, BSA, and ... from 4.5 to 8.5 and molecular weights ... standards provide calibrated references for the pI ...
... tube gel adaptors, 24 glass tubes ... grommets, stoppers. The PROTEAN II xi cell ... the versatility to perform a variety of ... electrophoresis, native, preparative, and gradient PAGE as ...
The PROTEAN II xi multi-cell 2-D conversion kit converts the PROTEAN II xi multi-cell to the PROTEAN II XL multi-cell for a wider format cell that accepts 17 to 18 cm IPG strips....
StemSep Anti-Phycoertherin Tetrameric Antibody Complexes, 2 mL for labeling 1x10 9 cells. Cross-linking Reagent for StemSep Separations of Cells Labeled with PE-conjugated Antibody....
Biology Products: