Navigation Links
UC Davis bench-to-bedside research: Promising treatment in clinical trials
Date:3/26/2009

properties of the s-EH inhibitors to the stage where we could present a convincing picture to venture groups of compounds ready to move to the clinic."

In 2005, the company raised more than $51 million in Series A financing led by Frazier Healthcare Ventures, Alta Partners, Three Arch Partners, Burrill & Company and Altitude Life Science Ventures.

Today, the biotech company, based in Hayward, is dedicated to the discovery and development of novel drugs to treat type 2 diabetes, hypertension and inflammatory disorders, Hammock said. It is billed as the "world's leading company focused on s-EH, an important enzyme for the metabolism of arachidonic acid that plays an essential role in metabolic, inflammatory and cardiovascular physiology."

"Our main goal," Hammock said, "was to set up a system of a science-driven company where we reduce the cost of drug registration by using very good incisive science. We also want to reward and motivate the people who do the work; provide a funding and training environment to help teach students and postgraduates to write proposals; and allow scientists to move between an academic and industrial environment in the early stage to help determine career directions."

Another goal: a low-cost, affordable drug. "The sickest people in the world, of course, cannot pay for the drugs they need," Hammock said. "The chemistry developed around the s-EH inhibitors allows us to make powerful but inexpensive drugs that could be produced in developing countries."

Meanwhile, the clinical trials under way represent two firsts, said James Sabry, president and chief executive officer of Arte Therapeutics. "This is the first clinical study of a s-EH inhibitor in patients, and the first study designed to establish proof of concept that s-EH inhibition modulates glucose metabolism or blood pressure in patients with impaired glucose tolerance and hypertension."

."AR9281 has demonstrated an excellent
'/>"/>

Contact: Kathy Keatley Garvey
kegarvey@ucdavis.edu
530-754-6894
University of California - Davis
Source:Eurekalert  

Page: 1 2 3 4 5

Related biology news :

1. UC Davis research shows that newly discovered drug reduces heart enlargement
2. UC Davis researchers find molecule that targets brain tumors
3. UC Davis discovery offers hope for treating kidney cancer
4. UC Davis team refines cancer treatments to reduce potential nerve damage
5. UC Davis researchers exploring gene therapy to fight AIDS
6. UC Davis researchers discover Achilles heel in pancreatic cancer
7. UC Davis researchers discover a key to aggressive breast cancer
8. UC Davis chemical ecologist wins major award
9. UC Davis researchers discover new drug target for inflammatory disease
10. UC Davis researchers define characteristics, treatment options for XXYY syndrome
11. UC Davis researcher leads climate-change discovery
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UC Davis bench-to-bedside research: Promising treatment in clinical trials
(Date:8/28/2014)... ROCHESTER, Minn. A Mayo Clinic researcher and his ... speed up and enhance the process of re-engineering cells ... that uses network biology methods to aid stem cell ... cell engineering are described in two back-to-back papers in ... has a broad range of uses for all types ...
(Date:8/28/2014)... peer groups and clinicians is critical to the ... University of Georgia research. , A qualitative study ... determined that role models for successful breastfeeding help ... , "Mothers who received that support are more ... co-author Alex Anderson, an associate professor in the ...
(Date:8/28/2014)... A unique method for delivering compounds that ... HIV and AIDS may be possible, thanks ... Agricultural Sciences., A semi-soft vaginal suppository made ... loaded with the antiviral drug Tenofovir provides ... against the spread of sexually transmitted infections ...
Breaking Biology News(10 mins):New tool aids stem cell engineering for medical research 2Breastfeeding study shows need for effective peer counseling programs 2Sensory-tested drug-delivery vehicle could limit spread of HIV, AIDS 2Sensory-tested drug-delivery vehicle could limit spread of HIV, AIDS 3
... analysis of a skull from the most complete early ... complex human brain may have evolved more rapidly than ... other human characteristics. While some features of ... precision-grip hand, the brain was more ape-like, says Emory ...
... faster than ever and not only when it ... bodies are reaching puberty at an increasingly earlier age, ... adult lives. That,s bad news, according to Tel Aviv ... Hyperostosis Frontalis Interna (HFI), a hormonal condition once typically ...
... it comes to human evolution. That seems to ... humans, somewhere in Africa during the last 20-60 thousand ... amounts of genetic material to their offspring who are ... and a team of evolutionary biologists, geneticists and mathematicians ...
Cached Biology News:Sediba hominid skull hints at later brain evolution 2Sediba hominid skull hints at later brain evolution 3Is estrogen going to your head? 2Is estrogen going to your head? 3Evolution's past is modern human's present 2Evolution's past is modern human's present 3
(Date:8/29/2014)... DIEGO, Aug. 29, 2014  Pfenex Inc. (NYSE ... the development of high-value and difficult to manufacture ... update and reported financial results for the second ... the successful completion of our initial public offering, ... our biosimilar product candidates, derived from our proprietary ...
(Date:8/29/2014)... August 29, 2014 The global ... billion in 2019. It is expected to grow ... 2019, and was valued at $1.8 billion in ... Transparency Market Research. , For more information regarding ... . , The research report, titled “Companion Diagnostics ...
(Date:8/29/2014)... August 29, 2014 Pittcon is pleased ... and colleague Koichiro Matsuda, Horiba Scientific, have organized a ... 5, 2014. JASIS , Asia’s largest analytical and ... in Makuhari Messe, Japan. , The four speakers ... Bioanalysis from Single Molecules to Single Cells” will present ...
(Date:8/29/2014)... 29, 2014 Local veterinarian, Dr. Keith ... are seeking candidates to participate in an investigational study ... The ultimate goal of this study is to determine ... one or two arthritically affected joints can help reduce ... Candidates for the current investigational study must be older ...
Breaking Biology Technology:Pfenex Reports Second Quarter 2014 Results and Provides Business Update 2Pfenex Reports Second Quarter 2014 Results and Provides Business Update 3Pfenex Reports Second Quarter 2014 Results and Provides Business Update 4Pfenex Reports Second Quarter 2014 Results and Provides Business Update 5Pfenex Reports Second Quarter 2014 Results and Provides Business Update 6Pfenex Reports Second Quarter 2014 Results and Provides Business Update 7Pfenex Reports Second Quarter 2014 Results and Provides Business Update 8Companion Diagnostics Market to Hit $5.6 Billion in 2019: Transparency Market Research 2Companion Diagnostics Market to Hit $5.6 Billion in 2019: Transparency Market Research 3Fifth Annual U.S. Symposium at JASIS Organized by Pittcon’s Program Chairman Hub MacDonald 2Burnt Hills Veterinary Hospital Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2
... researchers have created a nanoscale light sensor that can ... optic and electronic devices with new functionality. The team, ... at Madison, reports in Nature Photonics that ... The group, led by Jeremy Levy, a professor ...
... the 2010 ICO Prize for pioneering contributions to attosecond ... scientific discipline is to capture snapshots of the inner ... important insights into the actual course of chemical reactions, ... interactions between light and matter. "An attosecond is ...
... ... ... var shortURL = ""; BitlyCB.alertResponse = function(data) ... first one. for (var r in data.results) { first_result = data.results[r]; break; } for (var key in first_result) { ...
Cached Biology Technology:Pitt-led team develops nanoscale light sensor compatible with 'Etch-a-Sketch' nanoelectronic platform 22010 ICO Prize is awarded to TUM physicist Reinhard Kienberger 2MEDICAGO ANNOUNCES 2010 THIRD QUARTER FINANCIAL RESULTS 2MEDICAGO ANNOUNCES 2010 THIRD QUARTER FINANCIAL RESULTS 3MEDICAGO ANNOUNCES 2010 THIRD QUARTER FINANCIAL RESULTS 4MEDICAGO ANNOUNCES 2010 THIRD QUARTER FINANCIAL RESULTS 5MEDICAGO ANNOUNCES 2010 THIRD QUARTER FINANCIAL RESULTS 6MEDICAGO ANNOUNCES 2010 THIRD QUARTER FINANCIAL RESULTS 7MEDICAGO ANNOUNCES 2010 THIRD QUARTER FINANCIAL RESULTS 8MEDICAGO ANNOUNCES 2010 THIRD QUARTER FINANCIAL RESULTS 9