Navigation Links
UAlberta medical researchers discover how immune system kills healthy cells
Date:9/10/2013

Medical scientists at the University of Alberta have made a key discovery about how the immune system kills healthy cells while attacking infections. This finding could one day lead to better solutions for cancer and anti-viral treatments.

Faculty of Medicine & Dentistry researcher Colin Anderson recently published his team's findings in the peer-reviewed journal, Journal of Immunology. His team included colleagues from the United States and the Netherlands, and graduate students from the U of A.

Previous research has shown that when the immune system launches an aggressive attack on infected cells, healthy tissues and cells can be killed or damaged in the process. Anderson and his team discovered the mechanisms in the immune system that cause this "overkill" response.

"This opens the opportunity that one might be able to manipulate the immune system response to block collateral damage without blocking the killing of infected cells," Anderson explained.

"In the future this might be important in the development of clinical treatments in cases where the immune system response needs to be harnessed. For example, in treating various viral infections, the collateral damage caused during the immune system attack is a large part of the illness.

"In other cases, such as cancer or tumour treatments, one may want to increase the immune system's ability to kill collateral cells, in hopes of killing tumour cells that would otherwise escape during treatment and spread elsewhere in the body. Our research suggests there are other mechanisms that could improve cancer therapy and make it more efficacious. This finding could also help us understand why certain cancer treatments are more successful than others."

Anderson's team discovered "the weaponry the immune system uses to try and kill an infected or cancerous cell is not exactly the same as the weaponry that causes collateral damage to innocent bystander cells that
'/>"/>

Contact: Raquel Maurier
rmaurier@ualberta.ca
780-492-5986
University of Alberta Faculty of Medicine & Dentistry
Source:Eurekalert

Page: 1 2

Related biology news :

1. Diets high in salt could deplete calcium in the body: UAlberta research
2. Alnylam and UMass Medical School announce Tuschl I patent upheld in European opposition proceedings
3. Miniature pressure sensors for medical touch
4. Research!America says house funding levels for FY13 could undermine medical progress
5. Mainz University Medical Center attracts funding of Alexander von Humboldt Professorship
6. Medical device, health professionals attend first national conference on value-driven engineering
7. Ultrasensitive biosensor promising for medical diagnostics
8. UH Case Medical Center, CardioKinetix reveal promising data for treatment for heart failure
9. Tufts Medical Center researchers finds marker in premies saliva predicts readiness to feed by mouth
10. CDS Monarch Deploys DigitalPersona Strong Authentication Solutions for Secure Access to Electronic Medical Records
11. Nuisance seaweed found to produce compounds with biomedical potential
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/11/2014)... Amsterdam, NL, 11 September 2014 Patients with ... preparation and ingestion, which could contribute to poor ... Published studies have also suggested that PD is ... control groups. A report published in the ... in patients with mild-to-moderate PD, finding that the ...
(Date:9/11/2014)... South San Francisco, Calif., Sept. 11, 2014 UT ... a new collaboration to advance research and drug development ... of nerve cells. , This week, UT Southwestern researchers ... P7C3 compounds, a class that has been shown to ... previously licensed the P7C3 compounds to Dallas-based 2M Companies. ...
(Date:9/11/2014)... of oil that reached the Gulf of Mexico shore in ... first time such an estimate was reported, and the study ... and Technology . , The researchers found that 22,000 ... finding will help officials determine the persistence of oil on ... The study was conducted by the Center for Natural Resources ...
Breaking Biology News(10 mins):Few mild-to-moderate Parkinson's disease patients suffer from malnutrition, yet almost one-third are at risk 2Calico enters into exclusive collaboration with 2M to develop UTSW technology 2Calico enters into exclusive collaboration with 2M to develop UTSW technology 3NJIT researchers working to safeguard the shoreline 2
... , July 29, 2013 /PRNewswire-iReach/ -- In the current ... data. The bigger challenge is using data to make ... of Big Data, the must-attend big data event of ... Quality Research for Kaiser Permanente, will share his experience ...
... DALLAS July 29, 2013 A seafood contaminant ... like a spy to infiltrate cells and quickly open ... Southwestern Medical Center report. Vibrio parahaemolyticus ... host cells. One of those effectors, VopQ, almost immediately ...
... that beginning in January 2014 it will be publishing ... Institute of Biological Sciences (AIBS). Since 1964, ... overviews of current research in biology, accompanied by essays ... the conceptual underpinnings of the biological sciences., A peer-reviewed, ...
Cached Biology News:Kaiser Permanente's Robert Mangel to Speak at Rock Stars of Big Data: Register Now to Reserve Your Space 2Kaiser Permanente's Robert Mangel to Speak at Rock Stars of Big Data: Register Now to Reserve Your Space 3UT Southwestern researchers identify novel mechanism that helps stomach bug cause illness 2Oxford University Press to publish BioScience journal from 2014 2
(Date:9/12/2014)... Nasa Ames Research Base, Mountain View, CA (PRWEB) September ... announces the launch of its fundraising campaign on Indiegogo. ... producer Matt Rutherford, features Stephen Hawking, Buzz Aldrin, Shimon ... , Exponential technology is changing the world and there’s ... students how to harness it to help change the ...
(Date:9/11/2014)... it has uncovered the secret behind the unusual ... metal dichalcogenide (TMDC) materials, the two-dimensional semiconductors that ... , Using two-photon excitation spectroscopy, the researchers ... most promising of 2D materials, and found evidence ... energy states in which single photons can be ...
(Date:9/11/2014)... SARASOTA, Fla. , Sept. 11, 2014 ... novel anti-infective pharmaceuticals, announced today that the ... issued a ,Notice of Allowance, for patent ... Their Uses,.  The ,486 patent application relates ... act through gene-silencing and can be designed ...
(Date:9/11/2014)... TORONTO , Sept. 11, 2014 /PRNewswire/ - Portage ... Canadian Securities Exchange: PBT.U), announces that it intends ... to US$ 2 million for funding its preclinical ... Holding Company Limited, ("Biohaven"). The Company ... up to 20 million common shares at a ...
Breaking Biology Technology:Documentary Film that Follows Singularity University Students as They Change the World Launches its IndieGoGo Fundraising Campaign 2Excitonic dark states shed light on TMDC atomic layers 2Excitonic dark states shed light on TMDC atomic layers 3Lakewood-Amedex Receives Notice Of Allowance From The United States Patent and Trademark Office (USPTO) For A New Patent Covering Its nanoRNA Gene-Silencing Technology 2Lakewood-Amedex Receives Notice Of Allowance From The United States Patent and Trademark Office (USPTO) For A New Patent Covering Its nanoRNA Gene-Silencing Technology 3Portage Announces Proposed Private Placement 2Portage Announces Proposed Private Placement 3Portage Announces Proposed Private Placement 4
... increase their risk of developing diabetes, a study suggests. ... a resistance to insulin, the hormone that controls blood sugar ... how low testosterone levels in fat tissue can be instrumental ... present throughout the body. Low testosterone levels are linked to ...
... RICHLAND, Wash. Creators of a nanotech-based system that ... submarine, while providing a more environmentally friendly removal process, ... for 2012. The technology Self Assembled Monolayers on ... into future submarines to improve air quality for sailors ...
... a naturally occurring asphalt first appeared on roads in about ... the ancient city of Babylon. Under the onslaught of ... for anywhere near 2,700 years. But at Michigan Technological University, ... to fight off cracks, rutting and potholes. One of ...
Cached Biology Technology:Low testosterone levels could raise diabetes risk for men 2Clearing the air: PNNL technology wins award for improving submarine air quality 2Using nanoclays to build better asphalt pavement 2
... the MSn performance of the LTQ linear ... generate extensive structural information for the most ... Multiple dissociation techniques (PQD, ETD, CID) , ... , Fast polarity switching for high-sensitivity analysis ...
Request Info...
The Synergy HT utilizes a unique dual-optics design combined with monochromator wavelength selection to provide uncompromised performance in absorbance, fluorescence and luminescence reading modes. ...
... SYBR Green I nucleic acid gel stain ... that has bright fluorescence when bound to dsDNA ... for detecting dsDNA in gels using laser scanners ... acid stain has also found uses in capillary ...
Biology Products: