Navigation Links
U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
Date:8/22/2007

Researchers from the University of Minnesota Medical School and Brain Sciences Center at the Minneapolis VA Medical Center have identified a noninvasive and painless way to diagnose complex brain diseases. And its as simple as staring at a point of light. The research offers promise for a less-stressful, painless, and objective diagnosis for brain diseases, as well as a way to measure the effectiveness of different treatments for these diseases. Using magnetoencephalography (MEG) to record tiny magnetic fields in the brain, the researchers recorded brain cells communicating with each other while research subjects stared at a point of light.

After applying various mathematic algorithms, the researchers were able to classify the 142 research subjects by diagnosis. Study participants fell into one of six categories, including people with Alzheimers disease, chronic alcoholism, schizophrenia, multiple sclerosis or Sjogrens syndrome, as well as healthy controls.

The research, led by Apostolos P. Georgopoulos, M.D., Ph.D., professor of neuroscience, neurology, and psychiatry, will be published in the Aug. 27, 2007 issue of the Journal of Neural Engineering. This elegantly simple test allows us to glimpse into the brain as it is working, Georgopoulos said. We were able to classify, with 100 percent accuracy, the various disease groups represented in the group of research subjects. There are no good tests that measure the brain as it functions. Several tests exist to assess brain structure, but they reveal little of how the brain interacts. Currently, brain-related diseases are diagnosed with a combination of behavioral exams, psychiatric interviews, and neuropsychological testing, all which take time and can be hard on the patient, Georgopoulos said. This discovery gives scientists and physicians another tool to assess peoples disease progression, he said. In the future it could be applied when studying the effect of new treatments or drug therapies.

All behavior and cognition in the brain involves networks of nerves continuously interactingthese interactions occur on a millisecond by millisecond basis. The MEG has 248 sensors that record the interactions in the brain on a millisecond by millisecond basis, much faster than current methods of evaluation such as the functional magnetic resonance imaging (fMRI), which takes seconds to record. The measurements they recorded represent the workings of tens of thousands of brain cells.

Georgopoulos and his team were inspired to try to use the MEG as a diagnostic tool after discovering that neural interactions across human subjects were very similar. The team published on this novel way to assess the dynamic interactions of brain networks acting in synchrony in a 2006 issue of the Proceedings of the National Academy of Sciences. Now the team will continue to collect more data on the six disease groups, as well as begin to analyze research subjects with other brain diseases, including depression, post-traumatic stress disorder, autism, and Parkinsons disease, to see if the same technique can be applied.


'/>"/>
Contact: Sara E. Buss
buss@umn.edu
612-626-7037
University of Minnesota
Source:Eurekalert

Related biology news :

1. University of Minnesota researchers take new look at cellular suicide
2. Researchers discover way to make cells in the eye sensitive to light
3. Researchers find how protein allows insects to detect and respond to pheromones
4. Researchers Uncover Key Step In Manufacture of Memory Protein
5. NYU researchers simulate molecular biological clock
6. Researchers reveal the infectious impact of salmon farms on wild salmon
7. Researchers identify target for cancer drugs
8. Vital step in cellular migration described by UCSD medical researchers
9. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
10. UCSD researchers maintain stem cells without contaminated animal feeder layers
11. Researchers discover molecule that causes secondary stroke
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/21/2016)... , June 21, 2016 NuData Security announced ... new role of principal product architect and that ... director of customer development. Both will report directly ... officer. The moves reflect NuData,s strategic growth in ... to high customer demand and customer focus values. ...
(Date:6/9/2016)... TURKU, Finland , June 9, 2016 ... French National Police deploy Teleste,s video security solution to ensure ... France during the major tournament ... and data communications systems and services, announced today that its ... Police Prefecture to back up public safety across ...
(Date:6/2/2016)... 2016 Perimeter Surveillance & Detection ... Physical Infrastructure, Support & Other Service  The ... offers comprehensive analysis of the global Border Security ... revenues of $17.98 billion in 2016. Now: ... leader in software and hardware technologies for advanced video ...
Breaking Biology News(10 mins):
(Date:11/30/2016)... ... 30, 2016 , ... SSCI, the established leader in small-molecule cocrystal technology and ... FDA guidance on pharmaceutical cocrystals as drug substance . The Lunch and ... The event follows the successful November 15th event that took place in Burlingame, CA. ...
(Date:11/30/2016)... ... November 30, 2016 , ... ... development of a new orally administered treatment for Alzheimer’s disease (AD), today announced ... a Phase 2a clinical trial of T3D-959 in mild to moderate Alzheimer’s patients ...
(Date:11/30/2016)... ... ... With growth rates averaging more than 30% each year, Random42 has quickly outgrown ... expansion in their new office space. The new office has a fantastic location in ... industries, so Random42 Scientific Communication will fit right in. , Ben Ramsbottom, CEO ...
(Date:11/30/2016)... (PRWEB) , ... November 30, 2016 , ... ... a new and groundbreaking venture founded by Arianna Huffington, as part of the ... the uBiome Gut Explorer Kit, enabling purchasers to explore the microorganisms in their ...
Breaking Biology Technology: