Navigation Links
U of MN researchers discover noninvasive diagnostic tool for brain diseases
Date:8/22/2007

Researchers from the University of Minnesota Medical School and Brain Sciences Center at the Minneapolis VA Medical Center have identified a noninvasive and painless way to diagnose complex brain diseases. And its as simple as staring at a point of light. The research offers promise for a less-stressful, painless, and objective diagnosis for brain diseases, as well as a way to measure the effectiveness of different treatments for these diseases. Using magnetoencephalography (MEG) to record tiny magnetic fields in the brain, the researchers recorded brain cells communicating with each other while research subjects stared at a point of light.

After applying various mathematic algorithms, the researchers were able to classify the 142 research subjects by diagnosis. Study participants fell into one of six categories, including people with Alzheimers disease, chronic alcoholism, schizophrenia, multiple sclerosis or Sjogrens syndrome, as well as healthy controls.

The research, led by Apostolos P. Georgopoulos, M.D., Ph.D., professor of neuroscience, neurology, and psychiatry, will be published in the Aug. 27, 2007 issue of the Journal of Neural Engineering. This elegantly simple test allows us to glimpse into the brain as it is working, Georgopoulos said. We were able to classify, with 100 percent accuracy, the various disease groups represented in the group of research subjects. There are no good tests that measure the brain as it functions. Several tests exist to assess brain structure, but they reveal little of how the brain interacts. Currently, brain-related diseases are diagnosed with a combination of behavioral exams, psychiatric interviews, and neuropsychological testing, all which take time and can be hard on the patient, Georgopoulos said. This discovery gives scientists and physicians another tool to assess peoples disease progression, he said. In the future it could be applied when studying the effect of new treatments or drug therapies.

All behavior and cognition in the brain involves networks of nerves continuously interactingthese interactions occur on a millisecond by millisecond basis. The MEG has 248 sensors that record the interactions in the brain on a millisecond by millisecond basis, much faster than current methods of evaluation such as the functional magnetic resonance imaging (fMRI), which takes seconds to record. The measurements they recorded represent the workings of tens of thousands of brain cells.

Georgopoulos and his team were inspired to try to use the MEG as a diagnostic tool after discovering that neural interactions across human subjects were very similar. The team published on this novel way to assess the dynamic interactions of brain networks acting in synchrony in a 2006 issue of the Proceedings of the National Academy of Sciences. Now the team will continue to collect more data on the six disease groups, as well as begin to analyze research subjects with other brain diseases, including depression, post-traumatic stress disorder, autism, and Parkinsons disease, to see if the same technique can be applied.


'/>"/>
Contact: Sara E. Buss
buss@umn.edu
612-626-7037
University of Minnesota
Source:Eurekalert

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. NYU researchers simulate molecular biological clock
5. Researchers reveal the infectious impact of salmon farms on wild salmon
6. Researchers identify target for cancer drugs
7. Vital step in cellular migration described by UCSD medical researchers
8. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
9. UCSD researchers maintain stem cells without contaminated animal feeder layers
10. Researchers discover molecule that causes secondary stroke
11. Researchers find missing genes of ancient organism
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2017)... , May 16, 2017  Veratad Technologies, LLC ( ... online age and identity verification solutions, announced today they ... Conference 2017, May 15 thru May 17, 2017, in ... and International Trade Center. Identity impacts ... and in today,s quickly evolving digital world, defining identity ...
(Date:4/18/2017)... April 18, 2017  Socionext Inc., a global expert in SoC-based ... edge server, the M820, which features the company,s hybrid codec technology. ... by Tera Probe, Inc., will be showcased during the upcoming Medtec ... show at the Las Vegas Convention Center ... Click here ...
(Date:4/11/2017)... Research and Markets has announced the addition of the "Global ... ... at a CAGR of 30.37% during the period 2017-2021. ... based on an in-depth market analysis with inputs from industry experts. ... the coming years. The report also includes a discussion of the ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... (PRWEB) , ... October 10, 2017 , ... San Diego-based ... of its corporate rebranding initiative announced today. The bold new look is part ... as the company moves into a significant growth period. , It will also expand ...
(Date:10/10/2017)... ... October 10, 2017 , ... Dr. Bob Harman, founder and CEO of ... Rotary Club. The event entitled “Stem Cells and Their Regenerative Powers,” ... Dr. Harman, DVM, MPVM was joined by two human doctors: Peter B. Hanson, ...
(Date:10/10/2017)... ... October 10, 2017 , ... USDM Life Sciences ... the life sciences and healthcare industries, announces a presentation by Subbu Viswanathan and ... presentation, “Automating GxP Validation for Agile Cloud Platforms,” will present a revolutionary approach ...
(Date:10/9/2017)... ... October 09, 2017 , ... The award-winning American Farmer television ... quarter 2018. American Farmer airs Tuesdays at 8:30aET on RFD-TV. , With global ... the challenge of how to continue to feed a growing nation. At the same ...
Breaking Biology Technology: