Navigation Links
Tuberculosis strain spread by the fur trade reveals stealthy approach of epidemics
Date:4/11/2011

Patience may be a virtue in a person, but in an infectious disease, it is insidious. Witness tuberculosis, which can lie dormant in a human host for decades before bursting forth into infection. TB's stealthy nature has made it difficult to decipher how it spreads, seriously hampering efforts to control it. The World Health Organization estimates that a third of the people on Earth are infected.

Now, a study led by Stanford scientists has provided new insights into the behavior of tuberculosis by tracing the travels of a particular strain of the disease that was unintentionally spread among the indigenous peoples of western Canada by French Canadian voyageurs during the fur trade era. Although the disease was probably brought into the native populations repeatedly from about 1710 to 1870, it didn't spark an epidemic until the fur trade had largely ended, more than 150 years from when it was first introduced.

"We found there was this widespread, low-level dispersal of tuberculosis that did not become obvious until environmental changes occurred that created conditions conducive to epidemics," said Caitlin Pepperell, an infectious diseases specialist at Stanford.

The process, she said, resembles the way a smoldering fire can spread underground, through the roots of trees and brush, then burst into fire without warning.

"Tuberculosis epidemics are the outcomes of a process that has effectively been occurring underground," she said unlike smallpox, which quickly escalates into epidemics.

"This helps explain why it has been so extraordinarily difficult to eradicate TB."

The conditions that finally triggered epidemics in Canada in the late 1800s likely resulted from the relocation of native peoples onto reservations, where health conditions were often abysmal.

The biggest factor, she said, was probably malnutrition. The buffalo, once a dietary mainstay of indigenous peoples on the prairie, had been v
'/>"/>

Contact: Louis Bergeron
louisb3@stanford.edu
650-725-1944
Stanford University
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. 2 in 1: Multi-tasking protein provides new approaches for anti-tuberculosis drugs
2. Gates Foundation continues funding of tuberculosis research at Weill Cornell
3. TB-drugome provides new targets for anti-tuberculosis drug discovery
4. New tool in the fight against tuberculosis
5. Study finds possible persistence switch for tuberculosis
6. Bodys own proteins may lead the way in global fight against tuberculosis
7. Genome of bacteria responsible for tuberculosis of olive tree sequenced
8. Immune evasion common in many viruses, bacteria and parasites is uncommon in M. tuberculosis
9. Scientists take step toward simple and portable tuberculosis tests for developing world
10. Iowa State University researcher uncovers potential key to curing tuberculosis
11. In India: A search for more effective tuberculosis drugs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Tuberculosis strain spread by the fur trade reveals stealthy approach of epidemics
(Date:6/24/2015)... 22, 2015 Research ... of the "Huawei Ascend Mate 7 Fingerprint ... their offering. Huawei,s technological choice for ... direction than Apple,s and Samsung,s one. The Ascend ... by Fingerprint Cards, a main actor in capacitive ...
(Date:6/23/2015)... , June 23, 2015   MedNet ... that supports the entire spectrum of clinical research, ... ™ , the company,s intuitive, flexible ... awarded a Silver 2015 Stevie® Award by the ... Products & Services Website category.  The American Business ...
(Date:6/23/2015)... , June 23, 2015   Valencell, ... announced the results of a recent study that ... on the wrist during activity. In a study ... was compared along with the Apple Watch against ... measuring heart rate during activity. The study demonstrated ...
Breaking Biology News(10 mins):Huawei Ascend Mate 7 Fingerprint Sensor - Reverse Costing Analysis 2MedNet Solutions' iMedNet eClinical Wins Silver Stevie Award 2Valencell Delivers Breakthrough Heart Rate Accuracy on the Wrist 2Valencell Delivers Breakthrough Heart Rate Accuracy on the Wrist 3
... with a Star Trek twist, at the U.S. Department ... Determining who needs medical care at the scene ... bent over a victim, checking body temperature, heart rate, ... entire process can take 3-5 minutes per person. ...
... a "Dream Team." Lombardi Comprehensive Cancer Center,s ... and 12 of the nation,s top breast cancer researchers ... Up To Cancer (SU2C) to form a scientific "Dream ... brightest scientists will conduct new breast cancer research with ...
... Rice University researchers today announced that the first ... technology for removing arsenic from drinking water, will ... "Mexico,s debating the adoption of more stringent national ... water, and officials in Guanajuato are looking ahead ...
Cached Biology News:Triage technology with a Star Trek twist 2Lombardi scientist brings 'dream team' breast cancer research effort to GUMC 2Lombardi scientist brings 'dream team' breast cancer research effort to GUMC 3First 'nanorust' field test slated in Mexico 2
(Date:7/1/2015)... ... July 01, 2015 , ... The next-generation sequencing (NGS) clinical ... segments, including the molecular diagnostics industry. BCC Research reveals in its new report that ... lower test costs, and a growing need for better diagnostics as part of a ...
(Date:7/1/2015)... 1, 2015   Neuraltus Pharmaceuticals, Inc. , a ... groundbreaking drugs to treat neurodegenerative diseases such as ... Robert G. Miller , M.D., Director of the Forbes ... Pacific Medical Center in San Francisco, has been awarded ... million to help fund a Phase 2 clinical ...
(Date:7/1/2015)... -- Isagenix International, a leading global health and wellness ... and three Bronze Stevie® Awards at the 2015 Annual ... this month.The American Business Awards ... the U.S. "Winning is a tremendous ... cultivating talent, creating a unified team, and crafting the ...
(Date:7/1/2015)... InferMed , s decision ... augment Elsevier ... suite   Elsevier , a world-leading provider ... today the acquisition of  InferMed , a London ... InferMed,s Arezzo technology supports clinicians in choosing the most appropriate ...
Breaking Biology Technology:NGS-Based Diagnostics, the ‘Must-Have Platform’, Sends Market Segment CAGRs Soaring According to BCC Research 2NGS-Based Diagnostics, the ‘Must-Have Platform’, Sends Market Segment CAGRs Soaring According to BCC Research 3Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 2Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 3Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 4Isagenix Earns Nine American Business Awards 2Isagenix Earns Nine American Business Awards 3Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 2Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 3Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 4
... ADVENTRX Pharmaceuticals,Inc. (Amex: ANX ), a biopharmaceutical ... candidates for the treatment,of cancer and infectious diseases, ... officer is scheduled to present at the 20th,Annual ... 2007,at 8:30 a.m. Eastern Daylight Time. The conference ...
... the Phase III Clinical Development and ... of THR-100 in Developing Countries, LEUVEN, Belgium, ... biotechnology company focused on vascular disease, today,announced the ... International Limited (Hyderabad, India) for the manufacture of,THR-100, ...
... Inc. (the "Company") (Nasdaq: CMED ), a leading China-based,medical ... products and high intensity focused ultrasound tumor,therapy systems, today announced ... - China Day. Location: ... ...
Cached Biology Technology:ADVENTRX Pharmaceuticals to Present at the 20th Annual Bear Stearns Healthcare Conference 2ThromboGenics Announces Successful Completion of Technology Transfer to Bharat Biotech for Production of Novel Thrombolytic Agent 2ThromboGenics Announces Successful Completion of Technology Transfer to Bharat Biotech for Production of Novel Thrombolytic Agent 3ThromboGenics Announces Successful Completion of Technology Transfer to Bharat Biotech for Production of Novel Thrombolytic Agent 4
... in the Microsart e.motion are sterile-sealed, without protective ... specially designed individual package on a band. ... membrane filter units ensures that they are perfectly ... band guarantees uniform dispensing of the individual membrane ...
...
These 22x40mm rectangular No.1 Corning cover glasses are made from No. 0211 zinc titania glass and are 0.16 to 0.19mm thick. • Approx. Pcs Oz : 73...
The model 55D Rocking Shaker provides the same Reliable quality as the 55S, but double the value. The 55D gives you an additional platform with a height of 3.25 in....
Biology Products: