Navigation Links
Trial seeks improved lung-cancer screening by combining imaging and biomarkers
Date:5/3/2012

National Jewish Health is seeking to refine and improve lung-cancer screening by combining a blood test with CT imaging to detect disease earlier and more effectively. The trial combines a CT chest scan and the EarlyCDT-Lung blood test to screen for cancer, and seeks to build on recent research demonstrating that CT screening alone can reduce lung-cancer mortality.

"We have learned that CT screening of high-risk patients can reduce lung-cancer deaths. But we need to enhance screening to detect a greater number of early-stage lung cancers. That is the patient's best chance of a cure," said James Jett, MD, Professor of Medicine at National Jewish Health and principal investigator on the trial. "Combining CT screening with biomarker tests, such as the EarlyCDT-Lung, may help us detect more lung cancers at earlier stage while reducing the number of biopsies or operations performed for non-canceorus abnormalities."

EarlyCDT-Lung, developed by Oncimmune, Inc., detects antibodies that a person's immune system produces in its attempt to fight cancer. It has been shown that some antibodies may be detectable as long as five years before symptoms develop.

The National Lung Cancer Screening Trial recently demonstrated that screening patients with a high risk of developing cancer can reduce lung-cancer deaths by 20 percent. However, the CT screening also produces many false alarms, or false positives, which can lead to invasive follow-up testing, such as biopsy or surgery, that ends up finding only benign (non-cancerous) abnormalities. Researchers believe that the combination of the two tests, with their different detection strategies, may work together to make a screening method that is effective both medically and economically.

Lung cancer is the number one cause of cancer deaths in the United States, killing about 160,000 Americans every year; more than breast, colon and prostate cancer deaths combined. Early detection of lung cancer dr
'/>"/>

Contact: William Allstetter
allstetterw@njhealth.org
303-398-1002
National Jewish Health
Source:Eurekalert

Page: 1 2

Related biology news :

1. Clinical trial launches to see whether vitamin D helps treat multiple sclerosis
2. New clinical trial explores novel noninvasive colon cancer screening test
3. Canadian Journal of Cardiology publishes new atrial fibrillation guidelines
4. Ottawa researchers to lead world-first clinical trial of stem cell therapy for septic shock
5. Study jointly led by UCSB researcher supports theory of extraterrestrial impact
6. Can industrial parks be more environmentally friendly?
7. Recruitment starts on MS hookworm trial
8. First vaccine against fatal visceral leishmaniasis enters clinical trial
9. Using online patient communities and new trial approaches to optimize clinical research
10. Sustainable land use strategies to support bioenergy described in Industrial Biotechnology journal
11. First industrial-scale foam forming research environment for forest sector
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... from scientists at the University of Kent has shown ... are regulated a breakthrough that could have a ... from Kent,s School of Biosciences uncovered the mechanism whereby ... known as actin filaments are ,fine-tuned, to ... filaments appear to completely stable, providing a framework for ...
(Date:7/29/2014)... affects 1 in 100,000 people characterized by a loss ... remains unknown, a new study by a team of researchers ... Germany and other European institutions confirms for the first time ... 6 July in Nature Genetics , is an important ... a sphincter in the lower esophagus opens, allowing food to ...
(Date:7/28/2014)... Amundsen reached the South Pole in 1911, but new ... any human. , Using data from 16 ice cores ... including the South Pole, a group led by Joe ... Nevada, created the most accurate and precise reconstruction to ... new record, described in an article published today in ...
Breaking Biology News(10 mins):Mysterious esophagus disease is autoimmune after all 2Lead pollution beat explorers to South Pole, persists today 2Lead pollution beat explorers to South Pole, persists today 3
... to check out the complete report on the HIV ... new evidence that adult HIV infection rates have decreased in ... as increased use of condoms, delay of first sexual experience ... declines. The new UN report also indicates, however, that overall ...
... Drinking a shot of smooth full-flavoured brandy this Christmas ... found. , Dr Gordon Troup from the School of ... to have supplementary medicinal health benefits ?and the better ... key to its benefit is antioxidants contained in the ...
... numerous problems in Russia, not the least of which ... ongoing study of 25- to 54-year-old Russian men living ... significant proportion consume "surrogate" alcohols, otherwise known as products ... Researchers have now analyzed the contents of these ...
Cached Biology News:Earliest European Farmers Left Little Genetic Mark On Modern Europe 2Earliest European Farmers Left Little Genetic Mark On Modern Europe 3Earliest European Farmers Left Little Genetic Mark On Modern Europe 4Russian 'surrogate' alcohols are a killer 2Russian 'surrogate' alcohols are a killer 3Russian 'surrogate' alcohols are a killer 4
(Date:7/29/2014)... , July 29, 2014 ... surgical equipment market (types, applications and geography) - Size, ... Report, Opportunities, Segmentation and Forecast, 2013 - 2020", suggests ... reach $12.1 billion by 2020 registering a CAGR of ... the breakthrough achieved by the electro surgical devices in ...
(Date:7/29/2014)... Hershey, PA & Rockville, MD (PRWEB) July 29, ... Immunomic Therapeutics, Inc. (ITI), a vaccine pioneer in ... the financial services firm Newport Coast Securities, Inc. ... , ITI is commercializing LAMP-vax technology, a breakthrough ... $25B+ vaccines and immunotherapy market. The company exclusively ...
(Date:7/29/2014)... DisasterTalk is a texting app which allows ... masts or other transmitters are down. The app can transmit ... the need for any Wi-Fi, and can also use a ... app has launched as a housing report finds ... risk of being affected by natural disasters. With the risk ...
(Date:7/29/2014)... California (PRWEB) July 29, 2014 The ... is a next generation approach to robotics. What sets ... is patent pending technology that allows them to communicate, ... all wirelessly over the internet. , “The invention is ... giving the little Droidles a life of their own, ...
Breaking Biology Technology:Global Surgical Equipment Market is expected to reach $12.1 billion by 2020 - Allied Market Research 2Global Surgical Equipment Market is expected to reach $12.1 billion by 2020 - Allied Market Research 3Immunomic Therapeutics Engages Newport Coast Securities, Inc. 2Immunomic Therapeutics Engages Newport Coast Securities, Inc. 3DisasterTalk App Could Save Lives as Report Reveals 8% of US Homes at Very High Risk of Natural Disaster 2Droidles, the Social Network of Robots and Open Source Platform for the Internet of Things, Launches for Crowd Funding on IndieGoGo.com 2
... , , , , , , ... Silvia Svegliati, Michele Luchetti, and Armando Gabrielli , ... Scientifico, Ancona, Italy , , ... , GC-rich sequences difficult to amplify by PCR. This ...
... , , , , ... up to 24 automated large-scale 6xHis-tagged , protein ... workstation. Using cleared lysates from bacterial cultures as starting material, ... can be purified under native or denaturing , ...
... , , , High-quality ... efficient gene silencing in eukaryotic cell culture by targeting complementary , ... , gene silencing in functional genomics studies. Now, ... service that includes a range of modifications , ...
Cached Biology Technology:Successful PCR amplification and subcloning of a GC-rich DNA fragment 2Successful PCR amplification and subcloning of a GC-rich DNA fragment 3Successful PCR amplification and subcloning of a GC-rich DNA fragment 4Successful PCR amplification and subcloning of a GC-rich DNA fragment 5Ni-NTA Superflow Columns - automated large-scale purification of 6xHis-tagged , proteins 2Ni-NTA Superflow Columns - automated large-scale purification of 6xHis-tagged , proteins 3Ni-NTA Superflow Columns - automated large-scale purification of 6xHis-tagged , proteins 4Custom and library siRNA for efficient gene silencing 2Custom and library siRNA for efficient gene silencing 3Custom and library siRNA for efficient gene silencing 4Custom and library siRNA for efficient gene silencing 5
... (100+kb), fosmid (40kb), and large plasmid insert ... othe BAC vector. On command 20-50 fold ... recombinant DNA purification. Available with blue-white screening ... for the highest insert stability. Kits include ...
MAGP-2 (C-19)...
... ZMD.473. Immunogen: Synthetic peptide derived ... mouse junctophilin-2. Specificity: Specific for ... (positive controls: mouse skeletal muscle homogenates ... Applications: Western blotting Immunohistochemistry(froz) ImmunofluorescenceStorage: Store ...
TGF-beta 2 MAb (Clone 8607)...
Biology Products: