Navigation Links
Trial seeks improved lung-cancer screening by combining imaging and biomarkers
Date:5/3/2012

National Jewish Health is seeking to refine and improve lung-cancer screening by combining a blood test with CT imaging to detect disease earlier and more effectively. The trial combines a CT chest scan and the EarlyCDT-Lung blood test to screen for cancer, and seeks to build on recent research demonstrating that CT screening alone can reduce lung-cancer mortality.

"We have learned that CT screening of high-risk patients can reduce lung-cancer deaths. But we need to enhance screening to detect a greater number of early-stage lung cancers. That is the patient's best chance of a cure," said James Jett, MD, Professor of Medicine at National Jewish Health and principal investigator on the trial. "Combining CT screening with biomarker tests, such as the EarlyCDT-Lung, may help us detect more lung cancers at earlier stage while reducing the number of biopsies or operations performed for non-canceorus abnormalities."

EarlyCDT-Lung, developed by Oncimmune, Inc., detects antibodies that a person's immune system produces in its attempt to fight cancer. It has been shown that some antibodies may be detectable as long as five years before symptoms develop.

The National Lung Cancer Screening Trial recently demonstrated that screening patients with a high risk of developing cancer can reduce lung-cancer deaths by 20 percent. However, the CT screening also produces many false alarms, or false positives, which can lead to invasive follow-up testing, such as biopsy or surgery, that ends up finding only benign (non-cancerous) abnormalities. Researchers believe that the combination of the two tests, with their different detection strategies, may work together to make a screening method that is effective both medically and economically.

Lung cancer is the number one cause of cancer deaths in the United States, killing about 160,000 Americans every year; more than breast, colon and prostate cancer deaths combined. Early detection of lung cancer dr
'/>"/>

Contact: William Allstetter
allstetterw@njhealth.org
303-398-1002
National Jewish Health
Source:Eurekalert

Page: 1 2

Related biology news :

1. Clinical trial launches to see whether vitamin D helps treat multiple sclerosis
2. New clinical trial explores novel noninvasive colon cancer screening test
3. Canadian Journal of Cardiology publishes new atrial fibrillation guidelines
4. Ottawa researchers to lead world-first clinical trial of stem cell therapy for septic shock
5. Study jointly led by UCSB researcher supports theory of extraterrestrial impact
6. Can industrial parks be more environmentally friendly?
7. Recruitment starts on MS hookworm trial
8. First vaccine against fatal visceral leishmaniasis enters clinical trial
9. Using online patient communities and new trial approaches to optimize clinical research
10. Sustainable land use strategies to support bioenergy described in Industrial Biotechnology journal
11. First industrial-scale foam forming research environment for forest sector
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... in German . ... to risky situations such as exposure to predators. Researchers ... in a long-term study on different populations of great ... and ambient temperature. High metabolic rates and low temperatures ... scenarios birds were more likely to approach potential predators. ...
(Date:9/30/2014)... perilous threats in today,s ocean. From overfishing and ... coral ecosystems are disappearing at unprecedented rates around ... corals surrounding the island of Moorea in French ... environment: coral guard-crabs. New research from the National ... Seabird McKeon and the museum,s predoctoral fellow Jenna ...
(Date:9/30/2014)... HONG KONG , Sept. 30, 2014 Winners of ... The Economist Events, Innovation Summit scheduled to take place at the ... At the summit, the award winners will share their experiences and ... people who have made a proven innovation over the past decade, ... the night before the summit. It will be the ...
Breaking Biology News(10 mins):Risky metabolism 2Smithsonian scientists discover coral's best defender against an army of sea stars 2Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 2Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 3Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 4Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 5Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 6Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 7
... OCTOBER 27, 2009 -- Phosphorus is an essential element ... have led to massive eutrophication problems in water bodies ... is at least partly responsible for offshore "dead zones," ... of Mexico. While wetlands often act as filtering or ...
... 2009 -- Worldwide demand for a safe and secure ... forefront of sustainability discussions; however many research programs have ... traditional public or formula grants. Researchers are now turning ... international plant breeding programs. Stakeholders from public and ...
... management experts from across federal science agencies will gather ... identifying research priorities, exploring research performance management, and assessing ... meeting is to develop a collaborative framework to ensure ... in a coordinated manner. "We are bringing ...
Cached Biology News:Expert to discuss phosphorus' impact on Gulf 'dead zone' 2How do we fund plant breeding? 2How do we fund plant breeding? 3
(Date:9/30/2014)... Toronto, Ontario, Canada (PRWEB) September 30, 2014 ... requirements based on 500 square feet. per employee, which included ... different world back then.” says Jeff Howell, partner at ... tenant advisory firm in Toronto. “By the year 2000, ... We are now seeing that number come down to 175 ...
(Date:9/29/2014)... the forefront of diagnostics today, with imaging techniques ... scanning, and NMR (nuclear magnetic resonance) increasing steeply ... of image resolution and quality still limit these ... A solution is hyperpolarization, which involves injecting the ... by following the distribution and fate of specific ...
(Date:9/29/2014)... , Sept. 29, 2014 Research ... "Oligonucleotide Synthesis Market by Product & Services, End-User , ... their offering. The global oligonucleotide synthesis ... from $1,070.7 million in 2014, growing at a CAGR ... synthesis market is categorized on the basis of products ...
(Date:9/29/2014)... batteries are efficient but involve a range of ... (lucerne seed) and pine resin and a clever ... with a highly interesting alternative. Their study will ... ChemSusChem . , ,We think our discovery can ... for the batteries of the future, says Daniel ...
Breaking Biology Technology:ITRA Global Reports on How Companies Are Squeezing More Employees into Less Office Space 2ITRA Global Reports on How Companies Are Squeezing More Employees into Less Office Space 3A safer approach for diagnostic medical imaging 2A safer approach for diagnostic medical imaging 3Oligonucleotide Synthesis (Diagnostics, PCR, QPCR, Gene Synthesis, NGS, DNA, RNAi) Market - Global Forecast to 2019 2Oligonucleotide Synthesis (Diagnostics, PCR, QPCR, Gene Synthesis, NGS, DNA, RNAi) Market - Global Forecast to 2019 3Smart, eco-friendly new battery to solve problems 2
... 11 Cardium Therapeutics,(Amex: CXM ) today ... http://www.anginaresearchstudy.com to provide patients, caregivers and,physicians with ... The AWARE study is evaluating the therapeutic effects ... (insufficient blood flow,within the heart muscle) and associated ...
... (HD) instruments recognized in premier program ... for the medical technology ... Systems,announced that the company,s RealHand High Dexterity (HD) instruments ... design,team did an excellent job thinking ,outside of the ...
... - RDEA119 Produced Significant Beneficial Effect in Animal Models of ... ... Effective Treatment for Gout -, SAN DIEGO, June 11 Ardea Biosciences, ... Company,s,lead mitogen-activated ERK kinase (MEK) inhibitor, RDEA119, demonstrating,its potent activity in animal models ...
Cached Biology Technology:Cardium Launches New AWARE Clinical Study Website 2Cardium Launches New AWARE Clinical Study Website 3Cardium Launches New AWARE Clinical Study Website 4Cardium Launches New AWARE Clinical Study Website 5Cardium Launches New AWARE Clinical Study Website 6Cardium Launches New AWARE Clinical Study Website 7Novare Surgical Wins Medical Design Excellence Award 2Ardea Biosciences Presents Inflammation Program Data for Arthritis and Gout at 2008 Annual European Congress of Rheumatology 2Ardea Biosciences Presents Inflammation Program Data for Arthritis and Gout at 2008 Annual European Congress of Rheumatology 3Ardea Biosciences Presents Inflammation Program Data for Arthritis and Gout at 2008 Annual European Congress of Rheumatology 4Ardea Biosciences Presents Inflammation Program Data for Arthritis and Gout at 2008 Annual European Congress of Rheumatology 5
Recorder REC-111 single-channel, 1. Category: Chromatography Systems & Accessories, Systems....
For the quantitative determination of cyclic AMP (cAMP) concentrations in cell culture supernates, serum, plasma, saliva, urine and cell lysates....
... Wide Range CRYETTE WR Cryoscope for molecular weight determinations for petroleum-based applications. Multiple solvents ... cyclohexanol, sulfolane. ... ... ...
... For the ultimate in utility and ... to meet the needs of the researcher. ... interior dimensions or as sheet material that ... enclosures. These isolators are autoclavable and non-cytotoxic ...
Biology Products: