Navigation Links
Trial seeks improved lung-cancer screening by combining imaging and biomarkers
Date:5/3/2012

National Jewish Health is seeking to refine and improve lung-cancer screening by combining a blood test with CT imaging to detect disease earlier and more effectively. The trial combines a CT chest scan and the EarlyCDT-Lung blood test to screen for cancer, and seeks to build on recent research demonstrating that CT screening alone can reduce lung-cancer mortality.

"We have learned that CT screening of high-risk patients can reduce lung-cancer deaths. But we need to enhance screening to detect a greater number of early-stage lung cancers. That is the patient's best chance of a cure," said James Jett, MD, Professor of Medicine at National Jewish Health and principal investigator on the trial. "Combining CT screening with biomarker tests, such as the EarlyCDT-Lung, may help us detect more lung cancers at earlier stage while reducing the number of biopsies or operations performed for non-canceorus abnormalities."

EarlyCDT-Lung, developed by Oncimmune, Inc., detects antibodies that a person's immune system produces in its attempt to fight cancer. It has been shown that some antibodies may be detectable as long as five years before symptoms develop.

The National Lung Cancer Screening Trial recently demonstrated that screening patients with a high risk of developing cancer can reduce lung-cancer deaths by 20 percent. However, the CT screening also produces many false alarms, or false positives, which can lead to invasive follow-up testing, such as biopsy or surgery, that ends up finding only benign (non-cancerous) abnormalities. Researchers believe that the combination of the two tests, with their different detection strategies, may work together to make a screening method that is effective both medically and economically.

Lung cancer is the number one cause of cancer deaths in the United States, killing about 160,000 Americans every year; more than breast, colon and prostate cancer deaths combined. Early detection of lung cancer dr
'/>"/>

Contact: William Allstetter
allstetterw@njhealth.org
303-398-1002
National Jewish Health
Source:Eurekalert

Page: 1 2

Related biology news :

1. Clinical trial launches to see whether vitamin D helps treat multiple sclerosis
2. New clinical trial explores novel noninvasive colon cancer screening test
3. Canadian Journal of Cardiology publishes new atrial fibrillation guidelines
4. Ottawa researchers to lead world-first clinical trial of stem cell therapy for septic shock
5. Study jointly led by UCSB researcher supports theory of extraterrestrial impact
6. Can industrial parks be more environmentally friendly?
7. Recruitment starts on MS hookworm trial
8. First vaccine against fatal visceral leishmaniasis enters clinical trial
9. Using online patient communities and new trial approaches to optimize clinical research
10. Sustainable land use strategies to support bioenergy described in Industrial Biotechnology journal
11. First industrial-scale foam forming research environment for forest sector
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... Dec. 15, 2014 Research and Markets ... of the "Samsung Galaxy S5 - Home ... to their offering. ... different sensing technology than the iPhone 5S, Samsung ... in its product. The Galaxy S5 ...
(Date:12/17/2014)... Dec. 15, 2014  HITLAB SM announced ... (GCP) audit to confirm its adherence to current ... accomplishment enables HITLAB to conduct regulated smart device ... principles for patient safety and research quality. ... access, quality, and delivery with innovative technology," said ...
(Date:12/17/2014)... DUBLIN , Dec. 16, 2014 Research ... announced the addition of the "Global Chemical ... http://photos.prnewswire.com/prnh/20130307/600769 ... is the increasing demand for medical sensors in ... patient data for quick and correct diagnosis during ...
Breaking Biology News(10 mins):Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2
... Wash. Richard D. Smith, Battelle Fellow at the U.S. ... one of 50 outstanding leaders in the 2007 Scientific American ... 50 key contributors in science and technology. Smith shared ... with a colleague from UCLAs David Geffen School of Medicine, ...
... Haven, Conn.A genetic mutation expands lesions in the aorta ... of the arteries, according to a study by Yale ... researchers found that mice engineered without the Akt1 gene ... signs of aortic atherosclerosis compared to their littermates. And, ...
... of space activities, a silent revolution is taking place ... the first human-rated spacecraft to be launched from Europe,s ... m3 pressurised module of the largest, most complex automated ... closed, fulfilling the most stringent rules of human spaceflight. ...
Cached Biology News:PNNL's Richard Smith named to prestigious Scientific American 50 list of outstanding leaders 2Final preparations for first human-rated spacecraft to be lauched from Europe's Spaceport 2Final preparations for first human-rated spacecraft to be lauched from Europe's Spaceport 3
(Date:12/19/2014)... -- Decision Resources Group finds that the Latin American ... compound annual growth rate through 2023. This is primarily ... increasing adoption of dental implants. Growing aesthetic consciousness in ... demand for dental biomaterials because they can improve the ... Other key findings from Decision Resources Group,s coverage ...
(Date:12/19/2014)... 18, 2014 LayerBio is an MIT ... wound care. The National Eye Institute (NEI) at the ... Phase I SBIR grant to develop a drug-eluting intraocular ... most common cause of vision loss in people over ... According to Dr. Ken Mandell, LayerBio’s Founder and CEO, ...
(Date:12/19/2014)... 2014 In contrast to traditional LED ... various colors, Valoya uses proprietary LED technology to incorporate ... possible uniformity which is critical in low proximity installations. ... accuracy throughout its lifetime which is up to four ... , "The investment cost was clearly higher when compared ...
(Date:12/19/2014)... -- Egenix, Inc. is pleased to announce that Lionel ... to succeed Donald Fresne ; Mr. Fresne has also ... member of the Board.  In recognition of the many contributions ... almost twenty years, the Board designated Mr. Fresne as Chairman ... a Search Committee to find a suitable replacement with Biotech ...
Breaking Biology Technology:Latin American Dental Biomaterial Market Will Expand at a 12 Percent Annual Growth Rate Through 2023 2Latin American Dental Biomaterial Market Will Expand at a 12 Percent Annual Growth Rate Through 2023 3LayerBio Awarded NIH Grant to Develop a Drug Delivery Device for Cataract Surgery 2
... said this week that she would like Wisconsin to double ... the Act 255 program. , ,In an interview, Burke said ... but she would like to double the tax credits from ... Act 255, which had bipartisan support, the state made available ...
... Wis. Small Tree Communications said it ... Chippewa Valley Angel Investing Network , which invested $445,000 in ... drivers and other products for Apple's Mac OS X. It ... million in funding has been allocated for the company to ...
... Wis. Fiserv, Inc. , the Brookfield-based provider ... Wisconsin companies to make the annual Fortune 500 ... , ,Fiserv, which reported $4.1 billion in annual revenue ... 488 after ranking 510th last year. The annual ranking will ...
Cached Biology Technology:Burke would like to double Act 255 angel tax credits 2