Navigation Links
Trial aims to advance prenatal diagnosis of genetic defects
Date:8/21/2013

NEW YORK (August 21, 2013) Reproductive genetics researchers at Columbia University Medical Center (CUMC) are leading a multicenter prospective clinical study investigating the effects of chromosomal abnormalities (duplicative or missing material) found prenatally through microarray analysis. The goal of the study is to gain further information on genetic variances previously not well reported in the medical literature and share it with parents during pregnancy.

Led by principal investigator Ronald J. Wapner, MD, professor and vice chair for research at CUMC's Department of Obstetrics and Gynecology and director of reproductive genetics at NewYork-Presbyterian Hospital/Columbia, the research is the next phase of a project to advance clinicians' ability to diagnose in utero conditions such as developmental delays, structural abnormalities, and treatable or life-threatening diseases.

"Parents of children found to have a genetic variance want a better understanding of what it means. Our goal is to give them as much information and support as possiblefrom detailed genetic counseling to ways to connect with other people expecting children with the same variance," said Dr. Wapner.

In December 2012, Dr. Wapner and colleagues published in the New England Journal of Medicine (NEJM) findings of a trial involving 4,400 patients at 29 centers nationwide. That study showed that microarray analysis of a fetus's DNA gave significantly more clinically relevant information than the standard method of analysis, known as karyotypinga visual analysis of the fetus's chromosomes. [Click here for a news release about that study.]

In the current studywhich has ongoing clinical recruitmentdata on babies included in the NEJM article will be augmented by data on patients recruited by 10 major prenatal diagnostic centers around the country that offer microarray to all their patients. Each center aims to recruit 1,000 patients. Of the anticipated 10,00
'/>"/>

Contact: Elizabeth Streich
eas2125@cumc.columbia.edu
212-305-3689
Columbia University Medical Center
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Ultrasound patch heals venous ulcers in human trial
2. UCLA stem cell gene therapy for sickle cell disease advances toward clinical trials
3. New sickle cell anemia therapy advances to Phase II clinical trials
4. Alios BioPharma initiates Phase 1 clinical trial for respiratory syncytial virus infection
5. Intermountain Medical Center reseachers develop new 3-D technology to treat atrial fibrillation
6. Elseviers Maturitas publishes clinical guide on endometrial assessment in postmenopausal women
7. Ecology, economy and management of an agro-industrial Amazon frontier
8. FDA approves Phase II of stem cell trial for ALS led by U-Ms Dr. Eva Feldman
9. A trial to find out the effectiveness of biocides against Vespa velutina
10. Sea level rise: Jeopardy for terrestrial biodiversity on islands
11. Mummy CT scans show preindustrial hunter gatherers had clogged arteries
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/16/2015)... Fingerprint Cards (FPC) raises the revenue guidance for ... at least 340 MSEK to that it will amount to ... growth and orders received the revenue guidance for 2015 is ... will exceed 1,500 MSEK to an updated guidance that revenue ... Due to receipt of orders of touch fingerprint sensors with ...
(Date:6/12/2015)... , June 12, 2015  Securus Technologies, ... technology solutions for public safety, investigation, corrections and ... its patent to electronically capture, analyze and identify ... facial recognition methods. This system can: ... by an enrollment and subsequent sign-on process is ...
(Date:6/9/2015)... -- Research and Markets  ( http://www.researchandmarkets.com/research/xsgs2s/gesture ) has ... & Touchless Sensing Market by Technology (Touch-based & ... (Biometric & Sanitary Equipment) & by Geography - ... offering. The total gesture recognition and ... 23.55 Billion by 2020 at a high CAGR ...
Breaking Biology News(10 mins):Fingerprint Cards Raises the Revenue Guidance for Q2 2015 and for the Full Year 2015 2Fingerprint Cards Raises the Revenue Guidance for Q2 2015 and for the Full Year 2015 3Securus Announces Patent Issued for Authorized Presence Verification During Video Visitation 2Global Gesture Recognition & Touchless Sensing (Technology, Application & Products) Market 2015-2020 2
... gene responsible for controlling a first key step in the ... the journal Nature tomorrow (Thursday 27 October 2005). , The ... place once a sperm enters an egg, giving it a ... animals. , The absence or mutation of this gene in ...
... to last year's groundbreaking toxicological study on water-soluble ... and Environmental Nanotechnology (CBEN) find that water-soluble carbon ... Moreover, the research finds that nanotubes, like buckyballs, ... , The findings come from the first toxicological ...
... the University of California, San Diego that appears in the ... of the species Uca crenulata may check out 100 or ... on a mate. , “As far as I know, no ... as the California fiddler crab,?said Catherine deRivera, who conducted the ...
Cached Biology News:Scientists unpick genetics of first 15 minutes of life 2Modifications render carbon nanotubes nontoxic 2Modifications render carbon nanotubes nontoxic 3Biologist Discovers What May Be World’s ‘Pickiest?Mates 2Biologist Discovers What May Be World’s ‘Pickiest?Mates 3
(Date:7/3/2015)... ... 03, 2015 , ... The global failure analysis market is expected to reach ... bioscience market is expected to grow at the highest CAGR of 8.46%; its growth ... the research labs and academic institutions for root cause analysis of failure. The market ...
(Date:7/2/2015)... , ... July 03, 2015 , ... Cuvettes have been used in countless labs for ... to find the cuvette they needed. As expected, this was a daunting and tiring ... wrong part because they were not able to navigate the complex catalog structure. , Now ...
(Date:7/2/2015)... Memphis, TN (PRWEB) , ... July 02, 2015 ... ... in the development and manufacturing of surgical instruments in Orthopedics, announced today the ... orthopedic contract-manufacturing and the world's largest provider of surgical instruments to the Spine ...
(Date:7/1/2015)... BANGALORE, India , July 1, 2015 ... that uses next generation sequencing technology to empower cancer ... Storrer as chief executive officer. In his expanded ... responsible for all strategy, business expansion and worldwide operations ... served as Strand,s chairman and CEO since its founding ...
Breaking Biology Technology:Failure Analysis Market to Grow at 7.52% CAGR to 2020 2Failure Analysis Market to Grow at 7.52% CAGR to 2020 3Failure Analysis Market to Grow at 7.52% CAGR to 2020 4Failure Analysis Market to Grow at 7.52% CAGR to 2020 5New Cuvette E-Commerce Website Launched by FireflySci 2In'Tech Medical Acquires Turner Medical to Become a World Leader in Orthopedic Contract-Manufacturing 2In'Tech Medical Acquires Turner Medical to Become a World Leader in Orthopedic Contract-Manufacturing 3Strand Life Sciences Names Scott A. Storrer CEO as Company Continues Global Expansion with Focus on Precision Medicine Product 2Strand Life Sciences Names Scott A. Storrer CEO as Company Continues Global Expansion with Focus on Precision Medicine Product 3
... Canary Foundation, a,nonprofit organization that funds research in early ... Sam Gambhir, has,been elected as a new member of ... one of the highest honors in the fields of ... National Academy of,Sciences, serves as adviser to the nation ...
... MOUNTAIN VIEW, Calif., Oct. 21 An ... difficult to treat allures clinicians,to the approach of ... potential, stem cell therapies are believed to treat ... at a fast pace; however,both adult and embryonic ...
... Findings confirm that NanoBio,s nanoemulsion technology is effective when ... used in therapeutic applications and vaccines, ... announced,today that it will present compelling new data in ... preclinical development programs,in onychomycosis, herpes labialis, cystic fibrosis and ...
Cached Biology Technology:Canary Foundation's Dr. Sanjiv Sam Gambhir Elected to the National Academies Institute of Medicine 2Innovation and Strong Therapeutic Potential Seen in Adult Stem Cells, According to Frost & Sullivan 2Innovation and Strong Therapeutic Potential Seen in Adult Stem Cells, According to Frost & Sullivan 3NanoBio to Announce Key Clinical and Preclinical Data in Nine Presentations at ICAAC/IDSA 2008 2
EnzChek cellulase substrate *blue fluorescent, 339/452...
Homo sapiens 4-aminobutyrate aminotransferase Antigen: Recombinant Protein...
... 0.5-10 Kb RNA Ladder is suitable for sizing single-stranded ... glyoxal or formaldehyde agarose gels. The ladder consists of ... 3 4 6 8 and 10 kb) to simplify ... than the other bands allowing easy orientation and identification ...
Human DCIR/CLEC4A Phycoerythrin MAb (Clone 216110)...
Biology Products: