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Tracking down the cause of mad cow disease
Date:10/8/2008

s allowed the prion protein to firmly attach to the vesicle membranes by way of the artificial anchor.

This new concept will allow production of sufficient quantities of proteins modified with GPI anchors for in-depth studies. Experiments with the artificial GPI prion protein should help to clarify the influence of membrane association on conversion of the protein into the pathogenic scrapie form. This should finally make it possible to track down the infectious form of the prion.


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Contact: Christian F. W. Becker
christian.becker@ch.tum.de
49-892-891-3343
Wiley-Blackwell
Source:Eurekalert  

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