Navigation Links
Tracing microbes between individuals towards personalized oral health care
Date:12/12/2010

December 13, 2010 The human body is home to a complex ecosystem of microbes increasingly recognized as having a critical role in both health and disease. Viruses can attack and change the composition of bacterial communities, yet little is known about how this might influence human health. In a study published online today in Genome Research (www.genome.org), scientists have performed the first metagenomic analysis of a bacterial immune system in humans over time, finding that the defenses of the oral microbiome are unique and traceable, information that could help personalize oral health care in the future.

With recent advances in sequencing technologies, researchers are now sampling the genetic diversity of entire microbial and viral communities at once, including those residing within us. Recent studies have investigated viral communities of the respiratory and digestive tracts, suggesting that viruses might influence the microbial ecosystem and health of the human host. Less is known about how viruses affect the oral microbiome, which could have significant implications for diseases of the oral cavity.

A strategy for monitoring the interaction between bacterial communities and viruses is to sequence specific bacterial DNA elements that confer acquired immunity against viral attack, called clustered regularly interspaced short palindromic repeats (CRISPRs). Bacteria integrate foreign DNA from encountered pathogens into "spacers" between the repeats, using the spacers to later recognize and respond to the attacker.

In this study, a team of scientists has for the first time analyzed the evolution of the CRISPR bacterial immune system over time in the human body, specifically investigating the oral microbiome. "We knew that bacteria developed specific resistance to viruses," said David Pride of the University of California, San Diego and lead author of the report, "but before this s
'/>"/>

Contact: Peggy Calicchia
calicchi@cshl.edu
516-422-4012
Cold Spring Harbor Laboratory
Source:Eurekalert

Page: 1 2

Related biology news :

1. Tracing natural hazards by taking Earths pulse
2. UV light nearly doubles vacuums effectiveness in reducing carpet microbes
3. Microbes may consume far more oil-spill waste than earlier thought
4. Progress toward treating infections by silencing microbes smart phones
5. Genomic comparison of ocean microbes reveals East-West divide in populations
6. Southern soils mitigate manure microbes
7. Ancient microbes responsible for breathing life into ocean deserts
8. Scientists discover how deadly fungal microbes enter host cells
9. Tiny marine microbes exert influence on global climate
10. How fast can microbes break down oil washed onto Gulf beaches?
11. UM School of Medicine study finds vaginal microbes vary among healthy women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... in French and Spanish . ... 2014Today, the CEC released its Conservation Assessment for the ... Conservation, which identifies 29 priority conservation areas in a ... different protected areas in the states of Texas, Coahuila, ... and semi-arid habitats inhabited by rare and endangered plants ...
(Date:4/23/2014)... a unique rhythmic sound, recorded for decades in the ... minke whale ( Balaenoptera bonaerensis ). First described and ... it sounded like a duck, the bio-duck sound has ... but its source has remained a mystery, until now. ... deployed acoustic tags on two Antarctic minke whales in ...
(Date:4/23/2014)... TX (4/23/14) -- Researchers have found evidence of ... factors that increase aggressive behavior in children, especially ... not all children exposed to prenatal smoking will ... will not," said Brian Boutwell, Assistant Professor at ... and senior author on the study. "One ...
Breaking Biology News(10 mins):Conservation priorities released for several protected areas along US-Mexico border 2Conservation priorities released for several protected areas along US-Mexico border 3Scientists identify source of mysterious sound in the Southern Ocean 2Scientists identify source of mysterious sound in the Southern Ocean 3Genetics risk, prenatal smoking may predict behavioral problems 2
... formed and how species remain separate are crucial questions in ... are often infertile or die when still in the womb. ... result of a cross between a sheep and a goat, ... example, because the sounds they make are a mixture of ...
... other planets and in extreme environments on Earth will ... under a five-year grant from NASA,s Astrobiology Institute for ... H. House, associate professor of geosciences, will lead an ... life, look for biological signatures in relevant ecosystems in ...
... release is available in Spanish . ... at the Institute for Research in Biomedicine (IRB Barcelona) ... Qumica" (ICIQ, Tarragona), have discovered a substance with the ... presents certain mutations that promote the appearance of cancer. ...
Cached Biology News:Turtle doves commit adultery 2Turtle doves commit adultery 3Penn State receives new NASA astrobiology grant 2Penn State receives new NASA astrobiology grant 3Design of a compound that stabilizes the main natural suppressor of tumors 2
(Date:1/15/2014)... Two champions of science, technology, engineering, and ... annual competition for middle and high school students designed ... study. The competition presents students with real-world problems experienced ... Mathematics, and Sciences is a program administered by ...
(Date:1/15/2014)... AudioNotch is the internet's leading provider of Notched Sound ... Patients listen to sound therapy that is tailor-made for ... to months, their tinnitus volume decreases. , AudioNotch has previously ... Notched White Noise. Now, AudioNotch is pleased to announce to ...
(Date:1/14/2014)... 2014  3D Communications, a leading provider of strategic communications services to ... events in the United States and ... Cox , JD, is returning to the firm,s Washington, ... 3D after more than two years of service as Associate Commissioner ...
(Date:1/14/2014)... MA (PRWEB) January 14, 2014 iLab Solutions, ... Detwiler as the new Director of Product Strategy. In this ... well as iLab sub-teams to guide in the development of ... iLab provides the maximum possible benefit to the scientific community ...
Breaking Biology Technology:Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Former FDA Associate Commissioner Returns To 3D Communications 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2
... Achieved an Objective Tumor Response by End of Four ... (Nasdaq: PPHM ) today reported that its ... in the first stage of its ongoing Phase II ... (NSCLC). The open-label, Simon two-stage study is designed ...
... Wis., Feb. 4 Mach One Corporation (Pink Sheets: ... develops biotechnology based solutions that produce positive, long term ... that it has signed a definitive agreement to acquire ... company that supplies ingredients to the food, feed and ...
... Kit provides a great introduction to the benefits of Shape Memory Alloys. ... labs, and provides both a comprehensive manual, and easy to follow demonstrations ... ... (PRWEB) February 4, 2009 -- Imagine a future where the only tool ...
Cached Biology Technology:Peregrine Pharmaceuticals' Bavituximab Achieves Primary Endpoint in First Stage of Phase II Lung Cancer Study 2Peregrine Pharmaceuticals' Bavituximab Achieves Primary Endpoint in First Stage of Phase II Lung Cancer Study 3Peregrine Pharmaceuticals' Bavituximab Achieves Primary Endpoint in First Stage of Phase II Lung Cancer Study 4Mach One Corporation Signs Definitive Agreement to Acquire Ceres Organic Harvest, Inc. 2Re-Shaping the Future with Shape Memory Alloys - SMA Starter Kit 2Re-Shaping the Future with Shape Memory Alloys - SMA Starter Kit 3
Conjugation services for Antibodies, Proteins, Oligos, Peptides, Beads, bioconjugation, antibody-oligonucleotide, LNA peptide, LNA protein, LNA antibody, HRP, Alkaline phosphatase, phycoerythrin, FIT...
SCP-1 (P-17)...
Immunogen: Purified native p24 from strain IIIB. Storage: -20 C, Avoid Freeze/Thaw Cycles...
Biotin d anti-mouse Tim-1...
Biology Products: