Navigation Links
Timely technology sees tiny transitions
Date:6/23/2010

Scientists can detect the movements of single molecules by using fluorescent tags or by pulling them in delicate force measurements, but only for a few minutes. A new technique by Rice University researchers will allow them to track single molecules without modifying them -- and it works over longer timescales.

In the current issue of Nanotechnology, a team led by Jason Hafner, an associate professor of physics and astronomy and of chemistry, has shown that the plasmonic properties of nanoparticles can "light up" molecular interactions at the single-molecule limit in ways that will be useful to scientists.

Hafner's method takes advantage of the ability of metal nanoparticles to focus light down to biomolecular scales through an effect called localized surface plasmon resonance (LSPR). The gold nanoparticles ultimately used in the experiment scatter light in visible wavelengths, which can be detected and spectrally analyzed in a microscope.

"The exact peak wavelength of the resonance is highly sensitive to small perturbations in the nearby dielectric environment," said graduate student Kathryn Mayer, the lead student on the experiment. "By tracking the peak with a spectrometer, we can detect molecular interactions near the surface of the nanoparticles."

Hafner first discussed their progress at a 2006 conference after a presentation on gold nanostars his lab had developed. "We had extremely preliminary data, and I said, 'Maybe we've got it.' I thought we were close," he recalled.

What took time was finding the right particle. "We started with nanorods, which don't scatter light well, at least not the small nanorods we produce in my lab. Then we tried nanostars and found they were very bright and sensitive, but each was a different shape and had a different peak wavelength."

The team settled on bipyramids, 140-nanometer-long, 10-sided gold particles that focus light at their sharp tips, creating a halo-
'/>"/>

Contact: David Ruth
druth@rice.edu
713-348-6327
Rice University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Gold Standard/Elsevier offers timely, reliable drug pricing data, including average wholesale price
2. Free Webinar to Focus on Commercializing University Technology
3. Conference to discuss sensing technology developments and opportunities
4. Michael Graetzel wins the Millennium Technology Prize
5. Success with cisgenics in forestry offers new tools for biotechnology
6. Massive resources now directed at sustainable animal waste technology
7. Field Museum technology project wins prestigious award
8. Cutting-edge vaccine research to be showcased at AAPS National Biotechnology Conference
9. Biotherapeutic Innovations on Display at AAPS National Biotechnology Conference
10. Space technology revolutionizes archaeology, understanding of Maya
11. New LLNL detection technology identifies bacteria, viruses, other organisms within 24 hours
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2014)... Research and Markets ( http://www.researchandmarkets.com/research/87pph8/global_facial ... "Global Facial Recognition Market 2015-2019" report to ... Facial recognition is a technology ... system measures the overall facial feature of a ... the distance between eyes. Facial recognition is used ...
(Date:12/10/2014)... You,ve been here before: you desperately need to sign into ... key or the answer to your secret question. What,s your ... Today, Hoyos Labs , a digital infrastructure security ... an end to the frustration that comes with usernames, passwords ... a user,s smartphone to acquire his or her biometrics to ...
(Date:12/10/2014)... 9, 2014     ...   Jifflenow, a ... solutions for business-to-business (B2B) events, today announced a ... mobile near-field communication (NFC), Bluetooth low energy (BLE), ... http://photos.prnewswire.com/prnh/20140612/691055) , Jifflenow will integrate its ...
Breaking Biology News(10 mins):Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3
... -- Foiling exfiltration . . . Computer hackers ... developed by a team led by Justin Beaver of Oak ... attackers who breach a system,s defense have a distinct advantage ... window into potentially sensitive data and their true identity and ...
... Two new studies by researchers at the University of ... that eating rate plays in the amount of food ... faster than women, heavier people eat faster than slimmer ... grains, among other findings. Kathleen Melanson, URI associate ...
... of Mediterranean mountains could expand by up to 350% due to ... to cold and humid conditions, such as beech and Sylvester pines, ... possible in the 21st century according to a model created to ... Sistema Central and the Sistema Ibrico (Spain). A team led ...
Cached Biology News:Story tips from the US Department of Energy's Oak Ridge National Laboratory, November 2011 2Story tips from the US Department of Energy's Oak Ridge National Laboratory, November 2011 3Story tips from the US Department of Energy's Oak Ridge National Laboratory, November 2011 4Researcher provides further evidence that slow eating reduces food intake 2Holm oaks will gain ground in northern forests due to climate change 2
(Date:12/22/2014)... , Dec. 22, 2014   Synthetic ... developer of pathogen-specific therapies for serious infections ... the microbiome, today announced positive topline safety ... clinical trial of SYN-004, the Company,s investigational ... Clostridium difficile (C. difficile) infection, ...
(Date:12/22/2014)... 22, 2014  Alternative Energy & Environmental Solutions, ... signed a letter of intent to acquire BioTechPharma ... patented a nanotechnology-based development platform used to create ... rapid on-site collection and testing to identify infectious ... in an immediate, non-invasive and cost-effective manner. ...
(Date:12/22/2014)... , Dec. 22, 2014  ( www.competitivehealth.com ) ... an online medical bill review and advocacy service, has ... the FREE WellCard Savings discount health services marketplace. ... that was more than they expected to pay. As ... health care costs, WellCard Savings is pleased to offer ...
(Date:12/22/2014)... 22, 2014 ITRA Global, one of ... of commercial real estate, has further expanded its global ... Perth and Brisbane, Western Australia, reports Mylinda Vick, CCIM, ... ITRA Global / ACORPP (Australian Corporate Property and ... company providing property services to a wide range of ...
Breaking Biology Technology:Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 2Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 4Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 5ALNE Announces Intention To Acquire BioTechPharma 2WellCard Savings Announces CoPatient Medical Bill Review Service for Members 2ITRA Global Continues International Expansion in Perth and Brisbane, Australia 2
... Biologics, Inc.  (NYSE Amex: SYN ), a ... for serious illnesses, announced today that Jeff Riley, the ... Capital Partners 24th Annual Growth Stock Conference. The conference ... Carlton in Dana Point, CA. Mr. Riley will present ...
... and LONGNAN CITY, China, March 6, 2012   Apexigen, ... Duyiwei Biological Pharmaceutical Co., Ltd. (GDBP), which is ... that they entered into a collaboration to grant ... commercialize APX004 in China.   APX004 is a humanized ...
... ORLANDO, Fla., March 6, 2012 CSL Behring announced ... Esterase Inhibitor (Human) within six hours of the onset of ... symptom relief than later treatment, according to data presented at ... Annual Meeting. While HAE patients treated within six hours of ...
Cached Biology Technology:Synthetic Biologics to Present at ROTH Annual Growth Stock Conference 2Apexigen and Shanghai Duyiwei Biotechnology Co. Ltd Sign a License and Collaboration Agreement to Develop and Commercialize APX004 2Apexigen and Shanghai Duyiwei Biotechnology Co. Ltd Sign a License and Collaboration Agreement to Develop and Commercialize APX004 3CSL Behring Study Confirms Early Treatment with Berinert® Provides Faster Resolution of Acute Hereditary Angioedema Symptoms 2CSL Behring Study Confirms Early Treatment with Berinert® Provides Faster Resolution of Acute Hereditary Angioedema Symptoms 3CSL Behring Study Confirms Early Treatment with Berinert® Provides Faster Resolution of Acute Hereditary Angioedema Symptoms 4
IKKbeta/IKK-2 Polyclonal Antibody 100 ug affinity purified rabbit polyclonal antibody. Reacts with human. Tested in Western blotting....
...
Request Info...
... The S.c. EasyComp Transformation Kit ... transformation-competent Saccharomyces cerevisiae cells. Advantages over ... spheroplast formation or LiCl methods include:- Cells ... than 30 minutes - Competent cell preparation ...
Biology Products: