Navigation Links
Therapeutic cloning gets a boost with new research findings
Date:3/24/2009

Therefore, the bottleneck effect limits the transfer of mutations from donor cells to cloned offspring."

Not only did the researchers find that SCNT does not lead to an increase in the frequency of point mutations in cloned mice, the team also found that naturally conceived fetuses and cloned fetuses that are the same age have similar rates of spontaneous mutation development. They attribute this finding to epigenetic reprogramming.

It is known in the scientific community that germ cells contain an epigenome, a programmed state of the genome, that keeps mutation rates low. They suggest this type of epigenome is found in germ cells because those cells are responsible for contributing genetic information to subsequent generations. Adult somatic cells (the donor cells in SCNT) have higher mutation rates and less stringent epigenetic programming to avoid mutations than germ cells, but offspring produced from somatic cells by cloning have mutation rates similar to those in offspring produced by natural reproduction, suggesting that the epigenome of an adult somatic cell is reprogrammed during cloning to maintain the genetic integrity of that cell's progeny.


'/>"/>

Contact: Christi Fish
christi.fish@utsa.edu
210-458-7584
University of Texas at San Antonio
Source:Eurekalert

Page: 1 2

Related biology news :

1. Therapeutic hypothermia is promising strategy to minimize tissue damage
2. Tufts University professor receives IADR Pharmacology/Therapeutics/Toxicology Award
3. Alzheimers disease therapeutic prevents long-term damage from TBI in pre-clinical studies
4. Magnetic nanoparticles navigate therapeutic genes through the body
5. New potential therapeutic target discovered for genetic disorder -- Barth syndrome
6. Acorda Therapeutics submits new drug application for Fampridine-SR in multiple sclerosis
7. A novel target for therapeutics against Staph infection
8. Mitochondria could be a target for therapeutic strategy for Alzheimers disease patients
9. New therapeutic target identified for rheumatoid arthritis
10. Simple chemical procedure augments therapeutic potential of stem cells
11. Bayhill Therapeutics and the Juvenile Diabetes Research Foundation announce research collaboration
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2015)... , May 20, 2015 /PRNewswire/ ... http://www.researchandmarkets.com/research/h8t4x6/5year ) has announced the addition ... the Global Iris Recognition Market"  report ... , ,This research service analyses trends ... the government and commercial sectors, globally. ...
(Date:5/19/2015)... 2015 Research and ... of the  "Genetic Testing Market Outlook 2018" ... , ,A recent report, Genetic Testing Market ... the current and future genetic testing market. ... working principles and types are covered in ...
(Date:5/11/2015)... 2015  Synaptics Incorporated (NASDAQ: SYNA ), ... announced the appointment of Wajid Ali ... reporting to Rick Bergman , President and ... Officer, Kathleen Bayless , who announced her ... Ali brings extensive financial management expertise to Synaptics, ...
Breaking Biology News(10 mins):Global Iris Recognition Market Report 2015 - 5-Year Opportunity Analysis 2Global Genetic Testing Market Outlook 2018 2Synaptics Appoints Wajid Ali as Senior Vice President and Chief Financial Officer 2
... of mothers with a higher pre-pregnancy body mass index (BMI) ... study published in September,s issue of the journal Pediatric ... say that the effect of a mother,s BMI on her ... trajectory towards lifelong metabolic health problems. The research team ...
... available in German . , Eutrophication ... may also be positive for the environment. And even ... a positive effect. Researchers from the Biogeochemistry Department at ... out that nitrogen fertilizer indirectly strengthens the self-cleaning capacity ...
... Foundation (IRSF) announced today that it is awarding over ... accelerate translational research to develop treatments for Rett syndrome. ... funding for biomedical and clinical Rett syndrome research. ... high quality, peer-reviewed basic and translational research grants that ...
Cached Biology News:Mother's BMI linked to fatter babies 2Nitrogen in the soil cleans the air 2IRSF awards over $650,000 for Translational Rett Syndrome research 2
(Date:5/28/2015)... , May 27, 2015 Research ... of Jain PharmaBiotech,s new report "Neuroprotection - ... This report describes the role of ... injuries of the nervous system as well as ... many of the underlying mechanisms of damage to ...
(Date:5/28/2015)... DryLet, LLC a biotechnology company ... as animal waste reduction, bioremediation, wastewater treatment, aquaculture ... treatment plants and restaurant kitchen settings, announced today ... June 3-5 in Des Moines, Iowa. , ManureMagic™ ... Street Journal article because of its industry-leading qualities ...
(Date:5/28/2015)... MIAMI BEACH, Fla. , May 28, 2015 /PRNewswire/ ... data supporting the anti-cancer potential of its growth hormone-releasing ... presentation at the 2015 ASCO Annual Meeting. The ... the target for Biscayne,s anti-cancer GHRH blockers, is present ... receptor status. These findings suggest that GHRH antagonists could ...
(Date:5/28/2015)... Sunnyvale, Californiaa (PRWEB) May 28, 2015 ... on “ The Changing Landscape of EMR/EHR Clinical Data ... Annual Meeting taking place in Washington, DC on June ... the challenges of integrating EMR/EHR systems with EDC, and ... the opportunities brought by eSource and electronic health records/electronic ...
Breaking Biology Technology:Global Neuroprotection Market Report 2015-2024 - Drugs, Markets and Companies 2Global Neuroprotection Market Report 2015-2024 - Drugs, Markets and Companies 3DryLet to Showcase Patented ManureMagic™ at the 2015 World Pork Expo, June 3-5 in Des Moines, Iowa 2Data Presented At 2015 ASCO Annual Meeting Shows Biscayne Pharmaceuticals' GHRH Antagonist Target Is Expressed Across All Breast Cancer Subtypes 2Data Presented At 2015 ASCO Annual Meeting Shows Biscayne Pharmaceuticals' GHRH Antagonist Target Is Expressed Across All Breast Cancer Subtypes 3Clinovo Presents at the DIA 2015 51st Annual Meeting in Washington, DC on June 14th-18th 2
... - In a criminal trial, as any fan of TV cop-and-court ... goes second. The accused can appear in deep trouble, at first ... carries the day. , ,Not only does that make for appealing ... in real life. Those who file the charges speak first, the ...
... planners that focus on developing greater metropolitan areas, we would ... Lake Michigan into southeastern Wisconsin, including Milwaukee. Some envision that ... from Milwaukee to Chicago. , ,There are already commuters from ... away as Milwaukee on a daily basis. That number seems ...
... comes to driving innovation, most businesses don't have large research ... does, but that didn't prevent a visiting HP executive ... is HP's director of software marketing for the Americas, advised ... with whom they can test and develop the beta versions ...
Cached Biology Technology:Here's why Wisconsin's stem cell patents are being challenged 2Here's why Wisconsin's stem cell patents are being challenged 3Here's why Wisconsin's stem cell patents are being challenged 4Chicago-Milwaukee "mega-metro" infrastructure improvements are critical 2Chicago-Milwaukee "mega-metro" infrastructure improvements are critical 3Chicago-Milwaukee "mega-metro" infrastructure improvements are critical 4Hewlett-Packard exec offers innovative counsel 2Hewlett-Packard exec offers innovative counsel 3
Superior homology search software - in all the flavours of blast, with increased sensitivity and speed...
Protein 3D structure prediction, via threading. Easy to use....
... Blot Processing Standard Tray (3 per ... gel staining and blot processing.Automated staining ... for proteins and nucleic acid analysis.Prepares ... and chromogenic detection.Programmable control of protocol, ...
DITHIOTHREITOL, 150UMOL, 1 EA. Dithiothreitol (DTT), 0.1 M Solution:, *0.1 M solution of DTT in high purity dH2O., *0.2 m filtered., *Storage: -20C. Category: SEQUENASE....
Biology Products: