Navigation Links
The genome sequence of Tibetan antelope sheds new light on high-altitude adaptation
Date:5/17/2013

May 17, 2013, Shenzhen, China---- Why Tibetan antelope can live at elevations of 4,000-5,000m on the Qinghai-Tibetan Plateau? In a collaborative research published in Nature Communications, investigators from Qinghai University, BGI, and other institutes provide evidence that some genetic factors may be associated with the species' adaption to harsh highland environments. The data in this work will also provide implications for studying specific genetic mechanisms and the biology of other ruminant species.

The Tibetan antelope (Pantholops hodgsonii) is a native of the high mountain steppes and semi-desert areas of the Tibetan plateau. Interestingly, it is the only member of the genus Pantholops. Tibetan antelope is a medium sized antelope with the unique adaptations to against the harsh high-altitude climate. For non-native mammals such as humans, they may experience life-threatening acute mountain sickness when visiting high-altitude regions.

In this study, researchers suggest that Tibetan antelopes must have evolved exceptional mechanisms to adapt to this extremely inhospitable habitat. Using next-gen sequencing technology, they have decoded the genome of Tibetan antelope and studied the underlying genetic mechanism of high-altitude adaptations.

Through the comparison between Tibetan antelope and other plain-dwelling mammals, researchers found the Tibetan antelope had the signals of adaptive evolution and gene-family expansion in genes associated with energy metabolism and oxygen transmission, indicating that gene categories involved in energy metabolism appear to have an important role for Tibetan antelope via efficiently providing energy in conditions of low partial pressure of oxygen (PO2).

Further research revealed that both the Tibetan antelope and the highland American pika have signals of positive selection for genes involved in DNA repair and the production of ATPase. Considering the exposure
'/>"/>

Contact: Jia Liu
liujia@genomics.cn
BGI Shenzhen
Source:Eurekalert

Page: 1 2

Related biology news :

1. The DOE Joint Genome Institute expands capabilities via new partnerships
2. Scientists sequence genome of sacred lotus, which likely holds anti-aging secrets
3. Saving the parrots: Texas A&M team sequences genome of endangered macaw birds
4. Mapping the embryonic epigenome
5. Genome sequencing provides unprecedented insight into causes of pneumococcal disease
6. A new cost-effective genome assembly process
7. Turtle genome analysis sheds light on the development and evolution of turtle-specific body plan
8. CNIO researchers capture the replication of the human genome for the first time
9. Saint Louis University, University of Toronto biologists help decode turtle genome
10. Genome study suggests new strategies for understanding and treating pulmonary fibrosis
11. Coelacanth genome surfaces
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... wild relative of the domestic tomato, has been published ... headed by Professors Neelima Sinha and Julin Maloof at ... genome information may help breeders produce tastier, more stress-tolerant ... journal Nature Genetics , was lead by Bjrn ... UC Davis labs carried out work on the transcriptome ...
(Date:7/28/2014)... of a new study suggest two ways to effectively address ... well in obese women, compared to women of a normal ... method, researchers say, but as the population has increased in ... for obese women. Studies have consistently found that obesity has ... may in turn affect how well the pill prevents pregnancy. ...
(Date:7/28/2014)... Jude Children,s Research Hospital study found that 73 percent ... their risk of developing metabolic syndrome and related health ... results appear in the current issue of the journal ... 1,598 adult survivors of childhood cancer in the study ... factors like high blood pressure, abdominal obesity, elevated triglyceride ...
Breaking Biology News(10 mins):Strategies identified to improve oral contraceptive success with obese women 2Unhealthy habits more than double risk of metabolic syndrome in childhood cancer survivors 2Unhealthy habits more than double risk of metabolic syndrome in childhood cancer survivors 3
... dominates a plant,s growth principally because it was there first, ... the plant. Collaborating teams from the University of ... Canada combined their expertise in molecular genetics and computational modelling ... encourages plants to thrive. Understanding of the action and ...
... , , , ... that a new market research report is available in its catalogue. ... Market , , http://www.reportlinker.com/p0119500/World-Dynamic-Signature-Verification-Market.html ... for Dynamic Signature Verification in US$ Thousands. The market for Dynamic ...
... RESTON, Virginia, September 17 WCC Smart Search ... for multi-modal fusion, today,announced that it has been selected ... their driver registration system. ELISE ID will be used,to ... existing databases,that contain over 20 million records. It will ...
Cached Biology News:Explaining why pruning encourages plants to thrive 2Reportlinker Adds World Dynamic Signature Verification Market Report 2Reportlinker Adds World Dynamic Signature Verification Market Report 3Reportlinker Adds World Dynamic Signature Verification Market Report 4Reportlinker Adds World Dynamic Signature Verification Market Report 5Reportlinker Adds World Dynamic Signature Verification Market Report 6Reportlinker Adds World Dynamic Signature Verification Market Report 7Reportlinker Adds World Dynamic Signature Verification Market Report 8Reportlinker Adds World Dynamic Signature Verification Market Report 9
(Date:7/28/2014)... 2014 Appistry, Inc. , a ... the power of genomics to next-generation medicine, announced today ... Challenge . , Two Appistry staff will be ... Center for Genome Resources, and Mr. Neil Miller, director ... Kansas City. Rounding out the panel are Appistry’s Dr. ...
(Date:7/28/2014)... -- Research and Markets has announced the addition ... report to their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... used to determine the size of a particle in a ... analyze the size of particles as it can affect the ... to determine the behavior and nature of a material, and ...
(Date:7/25/2014)... bacteria live in each person,s digestive tract. Scientists believe ... stave off harmful infections, but their role in human ... light on the role of these bacteria, a team ... recently tracked fluctuations in the bacterial populations of two ... in the July 25 issue of the journal ...
(Date:7/25/2014)... Pittsburgh, PA (PRWEB) July 25, 2014 ... annual Call for Topics for Conferee Networking. These two-hour ... similar interests to meet and resolve problems, discuss new ... , The deadline to submit a topic for consideration ... at pittcon.org . The Conferee Networking committee will ...
Breaking Biology Technology:Appistry Names Industry Experts from the National Center for Genome Resources and Mercy Children's, Kansas City, to Judge Pipeline Challenge Competition 2Global Particle Size Analysis Market 2014-2018 2Monitoring the rise and fall of the microbiome 2Monitoring the rise and fall of the microbiome 3Pittcon 2015 Announces Call for Topics for Conferee Networking Sessions 2
... the Georgia Institute of Technology have made important findings ... an electrical field on a surface-supported gold nanocluster changes ... flat structure. In another paper, they relate their discovery ... magnetic through oxygenation of gold nanowires. They also found ...
... ETEX Corporation, an advanced,biomaterials company, announced today that ... Health, Inc., Under the agreement, LifeNet Health ... to be mixed with ETEX,s proprietary,calcium phosphate to ... will manufacture EquivaBone(TM) in its Cambridge,facilities and market ...
... IOMI ) today announced that it will release fourth ... and hold a,conference call and live webcast to discuss ... 1:30 p.m. Eastern Time., Conference Call Details, ... 6 at 1:30 p.m.,Eastern Time via phone, please dial ...
Cached Biology Technology:Physicists discover gold can be magnetic on the nanoscale 2Physicists discover gold can be magnetic on the nanoscale 3Physicists discover gold can be magnetic on the nanoscale 4ETEX and LifeNet Health, Inc. Enter Agreement 2Iomai to Announce Fourth Quarter and Year-End 2007 Financial Results and Host Webcast on Thursday, March 6 2
Rabbit polyclonal to Testosterone 19 ( Abpromise for all tested applications). Antigen: Testosterone 19 CME HSA (Human)...
Kinase Buffer can be used to assay protein kinase activity...
Anti-Kusabira Orange Monoclonal Antibody Description: 100 g Research Focus: tag Storage: -20C Shipping Temperature: 4C...
alpha/beta-Tubulin Antibody Ship: Hot Store: -20 C...
Biology Products: