Navigation Links
The blood preserved in the pumpkin did not belong to Louis XVI

The work has been published in the Scientific Reports journal.

CSIC researcher Carles Lalueza-Fox, from the Institute of Evolutionary Biology (a joint centre of CSIC and Pompeu Fabra University-UPF), explains: "When the Y chromosome of three living Bourbons was decoded and we saw that it did not match with the DNA recovered from the pumpkin in 2010, we decided to sequence the complete genome and to make a functional interpretation in order to see if the blood could actually belong to Louis XVI".

The functional genome analysis was based on two main points, the genealogical line and the physical appearance, and in both cases the result was negative. According to the historical records that go back to his 16 great-great grandparents, Louis XVI had a very heterogeneous genealogical line in which central European ancestors predominated, mainly from the area that today is Germany and Poland, while the genome recovered from the pumpkin belongs to an individual with a clear French and Italian component. In terms of physical appearance, the sequenced DNA points to an average height in France at the time and brown eyes, while portraits and historical accounts describe Louis XVI as the tallest man on the court and with blue eyes.

Lalueza-Fox adds: "Beyond the anecdotal fact whether or not the DNA belongs to Louis XVI, we present here the first genome from a recent historical period. The techniques we used will be useful in forensic studies, in which more than recovering some informative genetic markers, it will be able to work with complete genomes".

According to the chronicles of the time, there were many citizens who went to the scaffold in which Louis XVI was executed to dip their handkerchiefs in the blood of the monarch and thus save a historic memory. In 2010, a study coordinated by Lalueza-Fox analyzed the blood from one of these handkerchiefs, which had stained the inside of the pumpkin, decorated with portraits of the protagonists of the French Revolution, in which it had been kept. That study confirmed that the blood belonged to a European man whose paternal lineage was very hard to find in current genetic databases.

Iigo Olalde, Federico Snchez-Quinto, Debayan Datta, Urko

Contact: Marta García Gonzalo
Spanish National Research Council (CSIC)

Related biology news :

1. UH biomedical engineer works to make blood transfusions safer
2. Novel marker discovered for stem cells derived from human umbilical cord blood
3. Researchers develop novel molecular blood group typing technique
4. Ancient shrimp-like animals had modern hearts and blood vessels
5. GW researcher invents mini heart to help return venous blood
6. Researchers present comprehensive roadmap of blood cells
7. Blood test may help predict whether a child will become obese
8. Protein called YAP gives blood vessels strength, shape
9. Microfluidic device with artificial arteries measures drugs influence on blood clotting
10. University of Cincinnati to study impact of blood microparticles in inflammation, injury
11. A*STAR scientists create stem cells from a drop of blood
Post Your Comments:
(Date:5/9/2016)... May 9, 2016 Elevay is ... to expanding freedom for high net worth professionals seeking ... today,s globally connected world, there is still no substitute ... ever duplicate sealing your deal with a firm handshake. ... by taking advantage of citizenship via investment programs like ...
(Date:4/26/2016)... BANGALORE, India and LONDON ... Infosys Finacle, part of EdgeVerve Systems, a ... ), and Onegini today announced a partnership to ... banking solutions.      (Logo: ... banks to provide their customers enhanced security to ...
(Date:4/15/2016)... Research and Markets has announced ... 2016-2020,"  report to their offering.  , ... global gait biometrics market is expected to grow ... 2016-2020. Gait analysis generates multiple variables ... to compute factors that are not or cannot ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... GUELPH, ON , June 27, 2016 /PRNewswire/ - BIOREM ... it has been advised by its major shareholders, Clean ... LP, United States based venture ... common shares of Biorem (on a fully diluted, as ... for the disposition of their entire equity holdings in ...
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... Parallel ... clinical trials, announced today the Clinical Reach Virtual Patient Encounter CONSULT module ... circle with the physician and clinical trial team. , Using the CONSULT module, patients ...
(Date:6/27/2016)... 2016  Liquid Biotech USA ... a Sponsored Research Agreement with The University of ... from cancer patients.  The funding will be used ... with clinical outcomes in cancer patients undergoing a ... be employed to support the design of a ...
(Date:6/24/2016)... 2016 Epic Sciences unveiled a liquid ... to PARP inhibitors by targeting homologous recombination deficiency ... new test has already been incorporated into numerous ... types. Over 230 clinical trials are ... including PARP, ATM, ATR, DNA-PK and WEE-1. Drugs ...
Breaking Biology Technology: