Navigation Links
The 'appetite-suppressing' effect of proteins explained
Date:7/6/2012

Frequently recommended in weight-loss diets, dietary proteins have proven effectiveness thanks to their appetite-suppressing effects. A team led by Gilles Mithieux, Director of Inserm's Unit 855 "Nutrition and the Brain" in Lyon, has managed to explain the biological mechanisms behind these properties. The researchers describe in detail the chain reactions triggered by digesting proteins, sending a 'satiety' message to the brain long after a meal. Their results, published on 5 July in the Cell review, will make it possible envisage improved care for obese or overweight patients.

The team of researchers from Inserm, CNRS and the Universit Clause Bernard Lyon 1 has managed to shed light on the sensation of fullness experienced several hours after a protein-rich meal. This sensation is explained by messages exchanged between the digestive system and the brain, initiated by the dietary proteins that are mainly found in meat, fish, eggs or even some cereal-based products.

In previous studies, researchers proved that consuming dietary proteins triggers glucose synthesis in the intestine, after periods of food assimilation (a function known as gluconeogenesis). The glucose that is released in the blood circulation (portal vein) is detected by the nervous system, which sends an "appetite-suppressing" signal to the brain. Best-known in the liver and kidneys from which it supplies other organs with sugar, gluconeogenesis in the intestine sends an "appetite-suppressing" message after meals, characteristic of the sensation of "fullness".

In this new study, the researchers managed to accurately describe how digesting proteins triggers a double-loop of chain reactions involving the ventral (via the vagus nerve) and dorsal (via the spinal cord) peripheral nervous systems.

The in-depth study of biological mechanisms identified the specific receptors (μ-opioid receptors ) found in the portal vein nervous system, at the outlet
'/>"/>

Contact: Inserm Press Office
presse@inserm.fr
INSERM (Institut national de la sant et de la recherche mdicale)
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Study offers new insights into the effects of stress on pregnancy
2. Scientists reconstruct pre-Columbian human effects on the Amazon Basin
3. The activity of a bacterial effector protein seen in molecular detail
4. Researchers at GW receive federal funds to study the effect earthquakes have on nuclear reactors
5. New report examines effects of trees killed by bark beetles on wildfire
6. The effect of treatment with antibiotics and vaccination against Q fever in sheep
7. Novel discovery by NUS scientists paves the way for more effective treatment of cancers
8. Lab tests show arthritis drug effective against global parasite
9. New evidence that many genes of small effect influence economic decisions and political attitudes
10. The gut could reveal effect of climate change on fish
11. WSU researchers say genes and vascular risk modify effects of aging on brain and cognition
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
The 'appetite-suppressing' effect of proteins explained
(Date:7/2/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/km7m5t/natural_language ... "Natural Language Processing Market by Type (Rule-Based, Statistical, ... Image Recognition) - Worldwide Forecast to 2020" ... vendors occupying the market are 3M, Apple, Dolbey ... Solutions, SAS Institute Inc., Verint Systems among various ...
(Date:7/2/2015)... 25, 2015 Research and ... "Next Generation Biometrics Market by Application, Technology, Function ... to their offering. The next generation biometrics ... at a CAGR of 17.9% between 2015 and 2020 ... for the market. Safran SA ( ...
(Date:7/2/2015)... Fingerprint Cards has received an order for its ... distributor World Peace Industrial Group (WPI), part of WPG Holdings. ... . Deliveries are planned to take place during Q3 ... manufacturers in Asia . The order value ... of approximately 2,200 MSEK for 2015. Jörgen Lantto, ...
Breaking Biology News(10 mins):Natural Language Processing Market by Type (Rule-Based, Statistical, and Hybrid), Technologies (Recognition, IVR, OCR, Pattern & Image Recognition) - Worldwide Forecast to 2020 2Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 2Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 3FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2
... January 17, 2014 -- The 2014 Annual Meeting of ... Forum, will kick off on January 22-25 in Davos-Klosters, ... World: Consequences for Society, Politics, and Business." Each year, ... around the world and provides an open platform to ...
... 2014 A new study exploring vitamin D levels in ... a new avenue of early intervention that may delay or ... are published in the Journal of Parkinson,s Disease . ... PD and found that higher plasma vitamin D levels were ...
... National Park Service (NPS) and outside experts, ... recommendations to conserve aerial, marine, and terrestrial populations ... U.S. national parks, often coming from distant regions of ... Conservation of Migratory Species in and out of U.S. ...
Cached Biology News:KAIST participates in the 2014 Davos Forum on Jan. 22-25 in Switzerland 2KAIST participates in the 2014 Davos Forum on Jan. 22-25 in Switzerland 3Higher vitamin D levels associated with better cognition and mood in PD patients 2National Park Service and outside experts collaborate to conserve migratory wildlife 2National Park Service and outside experts collaborate to conserve migratory wildlife 3
(Date:7/2/2015)... ... July 03, 2015 , ... Cuvettes have been used in countless labs for decades. In ... cuvette they needed. As expected, this was a daunting and tiring process looking at ... they were not able to navigate the complex catalog structure. , Now thanks to FireflySci, ...
(Date:7/2/2015)... ... July 02, 2015 , ... Sleepless nights will become obsolete as ... sleep, launched its Indiegogo campaign on June 23. Sound sleepers and the sleep deprived ... it effortless to use, while the integration of the Bluetooth speaker, alarm clock and ...
(Date:7/1/2015)... Mass. , July 1, 2015   ... most frequently cited advantages of Otezla are its ... safety profile, as reported by surveyed rheumatologists. Otezla ... launched for the treatment of active psoriatic arthritis ... The current standard of care includes conventional oral ...
(Date:7/1/2015)... , July 1, 2015  Axovant Sciences ... focused on the treatment of dementia, today announced ... on July 22 at 5:45 p.m. EDT following ... Alzheimer,s Association International Conference 2015 (AAIC). ... , Dr. Lawrence Friedhoff , ...
Breaking Biology Technology:New Cuvette E-Commerce Website Launched by FireflySci 2Luzi Smart Lamp Recently Launched Indiegogo Campaign 2Luzi Smart Lamp Recently Launched Indiegogo Campaign 3Surveyed Rheumatologists Report That Otezla's Oral Administration is its Single Greatest Advantage Over Currently Available Treatment Options 2Surveyed Rheumatologists Report That Otezla's Oral Administration is its Single Greatest Advantage Over Currently Available Treatment Options 3Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 2Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 3
... of Standards and Technology (NIST) have been the ... into zinc oxide (ZnO) nanowires during fabrication. The ... not well-understoodrole in important optical and electrical properties ... amounts of copper. , Although zinc oxide is ...
... 19 /Xinhua-PRNewswire-FirstCall/ -- 3SBio Inc.,(Nasdaq: SSRX ) ... focused on researching, developing, manufacturing and,marketing biopharmaceutical products, ... as an independent director of the Company. Mr. ... since August 2006, who has,tendered his resignation as ...
... Campbell Alliance, the leading,management consulting firm specializing ... that executives from its Brand Management and,Managed ... Annual Forum on Early,Stage Product Development and ... the Center for Business Intelligence,(CBI). The conference ...
Cached Biology Technology:Chemists measure copper levels in zinc oxide nanowires 23SBio Inc. Announces Change to the Board of Directors 2Campbell Alliance Brand Management and Managed Markets Practices to Speak at CBI's Early Commercialization Conference 2Campbell Alliance Brand Management and Managed Markets Practices to Speak at CBI's Early Commercialization Conference 3Campbell Alliance Brand Management and Managed Markets Practices to Speak at CBI's Early Commercialization Conference 4
... 2 mM sodium phosphate buffer, pH 6.5. ... is a major lysosomal aspartyl protease in ... proenzyme. Overexpression of cathepsin D in human ... of relapse and metastasis. Cathepsin D degrades ...
... Grade Thrombin is a highly purified preparation ... with appropriate vectors. The preparation is functionally ... is free of detectable contaminating proteases. Prepared ... by certified tests to be negative for ...
Rat Hepatocytes (RH) (>3,000,000 cells)...
Rat Cardiac Fibroblasts (RCF) (>500,000 cells)...
Biology Products: