Navigation Links
Texas Biomed reports faster, more economical method for detecting bioterror threats
Date:11/5/2012

Texas Biomedical Research Institute scientists in San Antonio have developed a faster, less expensive route to screen suitable tests for bioterror threats and accelerate the application of countermeasures.

The new process screens for pairs of affinity reagents molecular magnets that bind to and hold on to their targets, be they toxins, viruses or bacteria. That will enable countermeasures to be selected and utilized much faster than the current practice.

"Using crude extracts from E. coli, the workhorse bacterium of the biotechnology laboratory, the new route bypasses the need for purification and complex equipment, enabling screening to be performed in under an hour," said Andrew Hayhurst, Ph.D., a Texas Biomed virologist.

Normally, he said, such screening requires sophisticated costly equipment to purify and analyze the affinity reagents. Such analysis becomes a huge burden when hundreds of reagents need to be checked and can take weeks to months.

The process funded primarily by Texas Biomed and the San Antonio Area Foundation, and in part by the Defense Threat Reduction Agency and the National Institutes of Health (NIH) was described online in the November 5, 2012 issue of Nature Publishing Group's Scientific Reports.

"We need an inexpensive route to screen libraries of affinity reagents. It had to be simple and self-contained as we eventually needed it to work in the space-suit lab or hot zone," said Hayhurst.

His surprisingly simple scheme allows scientists to make stop-gap tests to any given biological threat in a matter of days, with the screening step completed in an hour. The goal now is to speed up the entire process to work within a single day.

Hayhurst initially developed the pipeline using llama antibodies as the affinity reagents to botulinum neurotoxins, known as the world's most poisonous poisons 100 billion times more toxic than cyanide and handled in a specialized biosafety cabinet at bios
'/>"/>

Contact: Joseph Carey
jcarey@txbiomed.org
210-258-9437
Texas Biomedical Research Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. SMU professor Louis Jacobs honored with prestigious award from Texas science teachers
2. EyeLock Inc. Brings High-Tech Iris Biometric Production to Texas
3. Newly discovered letters and translated German ode expand Texas link to infamous Bone Wars
4. Controlling gait of horses may be possible, says key study from Texas A&M
5. BP Biofuels, Texas AgriLife Research sign agreement to advance biofuel feedstock development
6. NSBRI renews space life sciences graduate programs at MIT, Texas A&M
7. University of Texas Medical Branch selected to manage Center for Polar Medical Operations
8. Mining cleanup benefits from Texas A&M expertise
9. Diet of early human relative Australopithecus shows surprises, says Texas A&M researcher
10. University of North Texas Health Science Center Advances Forensic Research by Investing in Semiconductor DNA Sequencing Technology
11. NASA satellite measurements imply Texas wind farm impact on surface temperature
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/27/2015)... , July 27, 2015  Synaptics Inc. ... human interface solutions, today announced that Huawei has ... touchscreen solution for its stylish smartwatch. Huawei chose ... proven reliability, low power and highly responsive human ... finger. Huawei designers also required a classic round ...
(Date:7/23/2015)... , July 23, 2015 Research and ... of the "Global Outlook of the Biometrics ... The global biometrics market is ... and commercial applications owing to the uptake of ... a transformation that enhances the growth of biometrics ...
(Date:7/21/2015)... 2015 Passwords have proven futile for ... recent U.S. Office of Personnel Management breach. Biometric ... conundrum, but developers and end-users are concerned about ... dilemma, Biometrics-as-a-Service provider HYPR Corp. announced today the ... third party integration. A video ...
Breaking Biology News(10 mins):Synaptics Touchscreen Solution Powers New Huawei Watch 2Synaptics Touchscreen Solution Powers New Huawei Watch 3Global Outlook of the Biometrics Industry 2015 2Global Outlook of the Biometrics Industry 2015 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 2HYPR Corp. Launches Industry First Biometric Tokenization Platform 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 4
... attacks in New York City prompted large increases in ... man-made and natural disasters. But, this funding has ... disaster funding distribution is deeply inefficient: huge cash infusions ... abruptly after interest wanes. These issues have exposed significant ...
... damage to the Fukushima 1 Nuclear Power Plant in 2011, ... of radioactive contamination on wild and cultivated plants. In a ... these experts examine the potential adverse effects of radioactivity on ... article focusing on the efforts of a research group led ...
... treat certain types of cancer protect the insulin-producing cells ... mellitus type 1 in mice. The medicine works by ... have been made by researchers from the University of ... of Southern Denmark working with researchers in Belgium, Italy, ...
Cached Biology News:Funding problems threaten US disaster preparedness 2Microalgae and aquatic plants can help to decrease radiopollution in the Fukushima area 2Cancer drug protects against diabetes 2
(Date:7/31/2015)... 31, 2015 China Cord Blood Corporation (NYSE: ... leading provider of cord blood collection, laboratory testing, ... today announced that the Company has filed its Annual ... Exchange Commission. The filed Form 20-F includes audited financial ... The Form 20-F can be accessed by visiting the ...
(Date:7/30/2015)... ... July 31, 2015 , ... Ralco is honored to ... the Lyon County Fair to be held August 5-9 in Marshall. The Ralco Enrichment ... meals come from and how agriculture impacts their daily lives. This unique exhibit also ...
(Date:7/30/2015)... , July 30, 2015   GenoSpace , ... the interpretation and analysis of genomic and other ... has joined the company as Vice President ... http://photos.prnewswire.com/prnh/20150730/250931 "GenoSpace partners ... integrate, interpret, analyze and explore complex sets of ...
(Date:7/30/2015)... ... July 30, 2015 , ... The 2015 Market Research ... on the current state of the global Propanol market with a focus on the ... Eastman, Dow, Carboclor, Mitsui Chemicals, Oxea, ISU Chemical, Sanofi, Royal Dutch Shell, LG Chem ...
Breaking Biology Technology:China Cord Blood Corporation Files Its Annual Report on Form 20-F 2Ralco Announces Primary Sponsorship of Ralco Enrichment Center at Lyon County Fair 2GenoSpace Introduces Matthew Fischer as Vice President of Sales and Marketing 2Global Propanol Market Technical Data and Manufacturing Analysis 2020 2Global Propanol Market Technical Data and Manufacturing Analysis 2020 3
... for October 31, 2008 at 11:00 am EASTERN, ... TRIB ), a leading developer and manufacturer of diagnostic ... results for the third quarter of fiscal year 2008 ... conference call for that same,day, Friday, October 31, 2008, ...
... WaferGen Biosystems,Inc. (OTC Bulletin Board: WGBS), a leading ... stem cell research systems,today announced that Alnoor Shivji, ... corporate presentation at the Seventh,Annual BIO Investor Forum. ... the Palace Hotel in San Francisco, WaferGen,s ...
... Inc.,(Nasdaq: SUPG ), a pharmaceutical company ... cancer therapies, today presented data on MP-470, ... at the 20th,EORTC-NCI-AACR Symposium on "Molecular Targets ... orally bio-available multi-targeted,tyrosine kinase inhibitor, showed encouraging ...
Cached Biology Technology:Trinity Biotech plc to Announce Third Quarter 2008 Financial Results on October 31, 2008 2WaferGen to Present at the Seventh Annual BIO Investor Forum 2SuperGen's MP-470 Demonstrates Clinical Tumor Regression When Combined with Standard of Care Chemotherapy 2SuperGen's MP-470 Demonstrates Clinical Tumor Regression When Combined with Standard of Care Chemotherapy 3SuperGen's MP-470 Demonstrates Clinical Tumor Regression When Combined with Standard of Care Chemotherapy 4
... Error-free cloning of BAC (100+kb), fosmid ... Greater insert stability than any othe BAC ... for high yields and easy recombinant DNA ... or transcription-free (pSMART VC) vectors for the ...
... ZMD.473. Immunogen: Synthetic peptide derived ... mouse junctophilin-2. Specificity: Specific for ... (positive controls: mouse skeletal muscle homogenates ... Applications: Western blotting Immunohistochemistry(froz) ImmunofluorescenceStorage: Store ...
UCP1/2/3 (FL-307)...
... For 100 slides. Immunocytochemistry.Sample types: suitable ... tissue labeling.Recommended cell number: 10 ... hours).Store at 2-8 C (except DAB: ... Screening & Cellular Assays, Assays . ...
Biology Products: