Navigation Links
Teens susceptible to hepatitis B infection despite vaccination as infants
Date:1/8/2013

New research reveals that a significant number of adolescents lose their protection from hepatitis B virus (HBV) infection, despite having received a complete vaccination series as infants. Results in the January 2013 issue of Hepatology, a journal published by Wiley on behalf of the American Association for the Study of Liver Diseases, suggest teens with high-risk mothers (those positive for HBeAg) and teens whose immune system fails to remember a previous viral exposure (immunological memory) are behind HBV reinfection.

Infection with HBV is a major global health concern even with the success of universal vaccination against the virus in infants. The World Health Organization (WHO) estimates two billion individuals worldwide have HBV infection, with 360 million chronic carriers of the hepatitis B surface antigen (HBsAg). In the U.S., the Centers for Disease Control and Prevention (CDC) state that up to 1.4 million Americans are living with chronic HBV.

In Taiwan, where the present study was conducted, mother-to-child transmission (vertical transmission) is responsible for much of the HBV cases in that country. In fact, Taiwan has long been an endemic area with an HBV infection rate of 95% and HBsAg carrier rate that is found in up to 20% of the general population. To combat this major health burden, Taiwan launched the world's first universal vaccination program in 1984, vaccinating newborns of infectious mothers then expanding to all newborns in 1986.

"Chronic HBV is a major health burden that leads to cirrhosis, liver cancer (hepatocellular carcinoma) and liver failure, shortening lives and placing a huge economic drain on society," said lead author, Dr. Li-Yu Wang from Mackay Medical College in New Taipei City, Taiwan. "While infantile HBV vaccination is highly effective, it is not 100% and our study examines the long-term success of the HBV vaccine in a high-risk population."

For the present study, 8733 high schoo
'/>"/>

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

Page: 1 2

Related biology news :

1. For pre-teens, kindness may be key to popularity
2. Parents talking to their teens about being overweight
3. Soybeans susceptible to man-made materials in soil
4. Glyphosate-resistant superweeds may be less susceptible to diseases
5. Molecular and protein markers discovered for liver transplant failure from hepatitis C
6. Height, weight and BMI changes seen in children treated with peginterferon alpha for hepatitis C
7. Levels of hepatitis C virus higher among African-Americans and males
8. ACRG and BGI report findings from genomics research on recurrent hepatitis B virus integration
9. Recapitulation of the entire hepatitis C virus life in engineered mouse cell lines
10. Scripps Research Institute scientists find promising vaccine targets on hepatitis C virus
11. Discovery provides blueprint for new drugs that can inhibit hepatitis C virus
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... modeling study suggests that fish consumption advisories for ... to long-lived contaminants like persistent organic pollutants (POPs). ... of researchers including University of Toronto Scarborough PhD ... at how different levels of environmental contamination, a ... chemicals in the body influenced exposure in her ...
(Date:4/17/2014)... in German . ... they also provide us with a continuous stream of information ... or sit still in a car the world glides ... retinas. Seemingly without effort, our brain calculates self-motion from this ... and a steady gaze during our own movements. Together with ...
(Date:4/17/2014)... professor Rajendra Singh Thursday as a "Champion of ... solar deployment in the residential, commercial and industrial ... of Electrical and Computer Engineering and director of ... local hero leading the charge across the country ... power and driving policy changes at the local ...
Breaking Biology News(10 mins):Fish consumption advisories fail to cover all types of contaminants 2How vision makes sure that little fish do not get carried away 2How vision makes sure that little fish do not get carried away 3How vision makes sure that little fish do not get carried away 4White House honors Clemson professor as 'Champion of Change' for solar deployment 2
... applauds the US Court of Appeals for the District of ... against the use of public funds for embryonic stem cell ... cell research and the nation,s scientific community. Most importantly, ... suffering from incurable diseases," says Susan L. Solomon, CEO of ...
... a groundbreaking new videojournal to complement the ... & Advanced Surgical Techniques has been ... ( http://www.liebertpub.com ). Videoscopy ( http://www.liebertpub.com/products/product.aspx?pid=390 ) ... of the latest techniques and technologies used ...
... ground to plant trees may be an excellent gateway to ... University of Maryland study, based on work with New York ... in environmental stewardship, the more s/he engages with other types ... Together ", which the researchers released to coincide with Arbor ...
Cached Biology News:Groundbreaking minimally invasive surgical videojournal launched by Mary Ann Liebert Inc. 2Digging in dirt, Arbor Day planting, may help build citizenship: UMD study 2
(Date:1/15/2014)... The Pittcon Organizing Committee is pleased to ... Tech , an e-Journal and producer of Food ... second year for the co-location of Food Labs Conference to ... that the registration fee to attend the two-day Food Lab ...
(Date:1/15/2014)... 15, 2014 Look inside the new ... for the lab, from fluid handling to instruments to ... ship when you order. , Preferred Solutions features ... from the L/S® model for precise flow control and ...
(Date:1/15/2014)... and SAN JOSE, California , ... biotechnology company developing antibody-drug conjugates for cancer, today announced the ... of Directors. Dr Reynolds has over 20 years, development experience ... Officer at Seattle Genetics. "I am delighted to ...
(Date:1/15/2014)... This webinar will focus on EMA and ... in biosimilars. , Regulatory frameworks are evolving many countries ... the complex nature of biopharmaceuticals makes the demonstration of ... challenging. Based on the specific aspects of biosimilar drug ...
Breaking Biology Technology:Pittcon Announces Second Year Partnership With Food Safety Tech 2Pittcon Announces Second Year Partnership With Food Safety Tech 3Cole-Parmer Begins 2014 with the Release of Preferred Solutions 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 3Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2
... Mylan Inc. (Nasdaq: MYL ) today ... company,s credit ratings, including the "Corporate Family Rating," to ... is stable.  According to Moody,s: "Mylan,s ... in the global generic pharmaceutical industry, its strong geographic ...
... a molecular diagnostics company, announced today the publication of ... which may influence the amount of fetal DNA found ... Kypros Nicolaides, MD, of Harris Birthright Research Centre for ... Kingdom. (Logo: http://photos.prnewswire.com/prnh/20120326/NY75864LOGO ) ...
... a metal surface at the scale of atoms and ... computer chips or the reflective silver in optical components ... may seem high-tech and precise, the technique has been ... physics. In a new study, Brown University engineers modeled ...
Cached Biology Technology:Moody's Upgrades Mylan 2Ariosa Diagnostics Announces Publication of Study on Influential Factors Affecting Fetal DNA Concentration in Blood of Pregnant Women 2How ion bombardment reshapes metal surfaces 2How ion bombardment reshapes metal surfaces 3
Mouse monoclonal [3G8] to MDMA ( Abpromise for all tested applications)....
Fluorescein isothiocyanate (FITC) mouse anti-human IFN-alpha2 50 ug...
Dog polyclonal to Porcine Pancreatic Islets of Langerhans Cells ( Abpromise for all tested applications). Antigen: Tissue / cell preparation (Pig): Sonicated crude membrane fraction of porcine p...
Anti-human C5/C5b, Clone 568, Monoclonal Antibody...
Biology Products: