Navigation Links
Teens susceptible to hepatitis B infection despite vaccination as infants
Date:1/8/2013

New research reveals that a significant number of adolescents lose their protection from hepatitis B virus (HBV) infection, despite having received a complete vaccination series as infants. Results in the January 2013 issue of Hepatology, a journal published by Wiley on behalf of the American Association for the Study of Liver Diseases, suggest teens with high-risk mothers (those positive for HBeAg) and teens whose immune system fails to remember a previous viral exposure (immunological memory) are behind HBV reinfection.

Infection with HBV is a major global health concern even with the success of universal vaccination against the virus in infants. The World Health Organization (WHO) estimates two billion individuals worldwide have HBV infection, with 360 million chronic carriers of the hepatitis B surface antigen (HBsAg). In the U.S., the Centers for Disease Control and Prevention (CDC) state that up to 1.4 million Americans are living with chronic HBV.

In Taiwan, where the present study was conducted, mother-to-child transmission (vertical transmission) is responsible for much of the HBV cases in that country. In fact, Taiwan has long been an endemic area with an HBV infection rate of 95% and HBsAg carrier rate that is found in up to 20% of the general population. To combat this major health burden, Taiwan launched the world's first universal vaccination program in 1984, vaccinating newborns of infectious mothers then expanding to all newborns in 1986.

"Chronic HBV is a major health burden that leads to cirrhosis, liver cancer (hepatocellular carcinoma) and liver failure, shortening lives and placing a huge economic drain on society," said lead author, Dr. Li-Yu Wang from Mackay Medical College in New Taipei City, Taiwan. "While infantile HBV vaccination is highly effective, it is not 100% and our study examines the long-term success of the HBV vaccine in a high-risk population."

For the present study, 8733 high schoo
'/>"/>

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

Page: 1 2

Related biology news :

1. For pre-teens, kindness may be key to popularity
2. Parents talking to their teens about being overweight
3. Soybeans susceptible to man-made materials in soil
4. Glyphosate-resistant superweeds may be less susceptible to diseases
5. Molecular and protein markers discovered for liver transplant failure from hepatitis C
6. Height, weight and BMI changes seen in children treated with peginterferon alpha for hepatitis C
7. Levels of hepatitis C virus higher among African-Americans and males
8. ACRG and BGI report findings from genomics research on recurrent hepatitis B virus integration
9. Recapitulation of the entire hepatitis C virus life in engineered mouse cell lines
10. Scripps Research Institute scientists find promising vaccine targets on hepatitis C virus
11. Discovery provides blueprint for new drugs that can inhibit hepatitis C virus
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... Roald Amundsen reached the South Pole in 1911, but ... before any human. , Using data from 16 ice ... continent, including the South Pole, a group led by ... Reno, Nevada, created the most accurate and precise reconstruction ... The new record, described in an article published today ...
(Date:7/28/2014)... of people in the United States have a circulatory ... can be painful and may even require surgery in ... muscle wasting and, in turn, limb amputation. , At ... (UTHealth) Medical School, scientists tested a non-surgical preventative treatment ... was associated with increased blood circulation. Their proof-of-concept ...
(Date:7/28/2014)... -- Fifteen years ago, MIT professor John Essigmann and colleagues ... an HIV drug. They thought if they could induce the ... and eventually die out a strategy that our immune ... such a drug, which caused HIV to mutate at an ... virus from patients in a small clinical trial reported in ...
Breaking Biology News(10 mins):Lead pollution beat explorers to South Pole, persists today 2Lead pollution beat explorers to South Pole, persists today 3Scientists discover genetic switch that can prevent peripheral vascular disease in mice 2Forced mutations doom HIV 2Forced mutations doom HIV 3Forced mutations doom HIV 4
... Slugs are every gardener,s enemy: They can destroy overnight, ... don,t like all plants in the same way they ... posed by the botanist and founder of Chemical Ecology, Ernst ... More than a hundred years later chemists from Friedrich-Schiller-University Jena ...
... hands and arms through innovative robotic and virtual reality-based video ... Sergei Adamovich, a biomedical engineer. Thanks to a ... Adamovich is developing better ways to rehabilitate people who have ... Preliminary laboratory results appear promising: ...
... 2010) Acidity is increasing in some regions of the ... ocean, where it is now recognized that increased levels of ... more acidic. These more acidic conditions in key parts of ... to new research published in the journal Estuaries and ...
Cached Biology News:Self-defense strategies of moss 2NJIT engineer helps stroke patients regain motor functions in hands, arms 2Changing Chesapeake Bay acidity impacting oyster shell growth 2Changing Chesapeake Bay acidity impacting oyster shell growth 3
(Date:7/29/2014)... a new way of manufacturing microstructured surfaces that ... self-assembly of carbon nanotubes, could exhibit a variety ... and strength, or the ability to repel water ... that mechanical forces can be used to direct ... we can independently control the mechanical properties ...
(Date:7/29/2014)... WARRINGTON, Pa. , July 29, 2014 /PRNewswire/ ... company dedicated to advancing a new standard of ... financial results on August 5, 2014 before the ... The Company will host a live teleconference ... day. During the conference call, Discovery Labs, management ...
(Date:7/29/2014)... TransVac Solutions, the trusted leader in automated ... for hospitals, will be exhibiting at booth #209 at ... & Technical Exhibition Aug. 3-6 in Chicago, Ill. ... hospitals cleaner, reducing infection risk and saving millions in ... Staff will be available at booth #209 to ...
(Date:7/29/2014)... Rock Hill, South Carolina (PRWEB) July 29, 2014 ... communicate with teams of people where cell phone masts or ... other iPhones up to 100 feet away without the need ... iPhones to target longer ranges. , The new app has ... 8% of US homes are at very high risk of ...
Breaking Biology Technology:A new way to make microstructured surfaces 2Discovery Labs to Report 2014 Second Quarter Financial Results and Hold Conference Call on Tuesday, August 5, 2014 at 9:00 a.m. Eastern Time 2TransVac Presents Cost Saving Technology at ASHE Conference for Keeping Hospitals Cleaner 2DisasterTalk App Could Save Lives as Report Reveals 8% of US Homes at Very High Risk of Natural Disaster 2
... Auxilium Pharmaceuticals, Inc. (NASDAQ: AUXL ), a specialty ... on Monday, May 9, 2011 before the opening of the ... call that day at 10:00 a.m. ET to discuss results ... to be used during the call will be available on ...
... or Encyclopedia Of DNA Elements project, has created an overview ... sequence. The April 19 publication of "A ... the journal PLoS Biology provides a guide for using the ... by the project. All of the data, tools to ...
... 21, 2011 Cord Blood America, Inc . ( ... umbilical cord blood stem cell preservation company focused ... families nationwide and internationally, is pleased to announce that its ... Incorporation effecting a reverse stock split. The vote ...
Cached Biology Technology:Auxilium Pharmaceuticals to Announce First Quarter 2011 Results and Conduct Conference Call on Monday, May 9, 2011 2Auxilium Pharmaceuticals to Announce First Quarter 2011 Results and Conduct Conference Call on Monday, May 9, 2011 3A user's guide to the encyclopedia of DNA elements 2Cord Blood America: Shareholders Approve Common Stock Reverse Split 2
Prepared in distilled water....
... RiboGreen RNA Quantitation Kit is one ... for the quantitation of RNA in ... 1000-fold more sensitive than absorbance measurements. ... be detected with fluorescence microplate readers ...
Request Info...
Recommend to use at up to 5000X dilutions for cell culture (e.g. Add 1 ul to 1 ml of culture medium.)...
Biology Products: