Navigation Links
TGen-led study discovers dramatic changes in bacteria following male circumcision
Date:4/16/2013

PHOENIX, Ariz. April 16, 2013 Male circumcision reduces the abundance of bacteria living on the penis and might help explain why circumcision offers men some protection against HIV, according to a study led by the Translational Genomics Research Institute (TGen).

Removing the foreskin caused a significant shift in the bacterial community or microbiome of the penis, according to a study published today by the online journal mBio.

This international collaboration focused on 156 men in Rakai, Uganda part of the world's largest randomized-controlled trial on male circumcision. Researchers showed that men who were circumcised as part of the study had 33.3 percent less bacteria on their penis than those who remained uncircumcised one year after the study began.

Researchers further showed that the decrease was primarily found in 12 types of bacteria, most of which were intolerant to oxygen.

Past studies have shown that circumcision reduces female-to-male HIV transmission, among other benefits. This study suggests a possible mechanism for HIV protection the shift in the number and type of bacteria living on the penis. Further studies will have to be done to demonstrate that a change in the penis microbiome can help reduce the risk of HIV transmission, according to the authors.

At the same time, understanding the mechanisms that underlie the benefits of male circumcision could help to identify new intervention strategies for decreasing HIV transmission, especially for populations with high HIV prevalence and in places where male circumcision is culturally less acceptable, the study says.

"We know that male circumcision can prevent HIV and other diseases in heterosexual men, but it is important to know why," said Dr. Lance Price, the Director of TGen Center for Microbiomics and Human Health and the study's senior author.

"We think that these dramatic changes in the penis microbiome may explain, at
'/>"/>

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. Mount Sinai study identifies new gene variations associated with heart rate
2. Study proposes alternative way to explain lifes complexity
3. Exercise or make dinner? Study finds adults trade one healthy act for another
4. BUSM researchers identify novel approach to study COPD and treatment efficacy
5. Sustainable fishing certification too lenient and discretionary, study finds
6. Methane emissions from natural gas local distribution focus of new study
7. Short daily walk might help teen smokers cut down or quit, new study says
8. Couch potatoes may be genetically predisposed to being lazy, MU study finds
9. Autism in black and white: NIH grant helps scientist study disorder in African Americans
10. Bird flu mutation study offers vaccine clue
11. Genes behind obesity mapped in large-scale study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/17/2015)... , March 17, 2015 MedNet ... specializing in clinical study management systems, is pleased ... attendance at ARENA,s Outsourcing in Clinical Trials Southeast ... event provides an excellent forum for MedNet to ... and affordable software-as-a-service (SaaS) eClinical technology platform. ...
(Date:3/12/2015)... 12, 2015 IriTech, a leading iris based ... the Texas Instruments Design Network, announced today that the ... its IriShield USB MK2120U device during a launching event ... distribution. The iris scanner is manufactured ... in India through its Indian ...
(Date:3/11/2015)... Research and Markets ( http://www.researchandmarkets.com/research/3p32qm/access_control ) ... Market by Product, Application & By Geography - Global ... offering. , This report predicts that the ... by 2020, with an estimated CAGR of 10.6%. ... types such as contact cards & readers, contactless cards ...
Breaking Biology News(10 mins):Connect With MedNet Solutions At Outsourcing In Clinical Trials Southeast 2Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 2Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 3Global Access Control (Cards & Readers, Biometrics, Controllers, Management Software) Market 2015-2020 - Analysis of the $10 Billion Market 2
... Worcester, Mass. Development of new therapies for ... heart attackswill be supported by a new production-scale microthread ... students and biomedical engineering faculty at Worcester Polytechnic Institute ... the final stages of testing and validation, and will ...
... , Ottawa, Ontario (April 30, 2012) In a ... and Aquatic Sciences, biologist Douglas Swain of the Gulf Fisheries ... of Oceanography present findings that suggest the delay in recovery ... attributed to increased predation by grey seals or other governing ...
... less weight more times is just as effective at building ... researchers that turns conventional wisdom on its head. The ... the point of fatigue. "We found that loads ... at inducing muscle growth and promoting strength," says Cam Mitchell, ...
Cached Biology News:WPI team scales-up production of biopolymer microthreads 2WPI team scales-up production of biopolymer microthreads 3WPI team scales-up production of biopolymer microthreads 4Light weights are just as good for building muscle, getting stronger, researchers find 2
(Date:4/1/2015)... 30, 2015 Research and Markets ... the "Forensic Technologies and Services - Global ... This report analyzes the US market ... by the following Segments: Forensic Databases, Forensic Consulting ... Annual estimates and forecasts are provided ...
(Date:4/1/2015)... , April 1, 2015  Spherix Incorporated ... committed to the fostering and monetization of intellectual ... a privately held full service global investment bank ... issued an industry note featuring Spherix. ... CFA, a Senior Analyst at Chardan, was published ...
(Date:4/1/2015)... National recruitment firm Slone Partners is ... Head of Sales at Optimal Medicine, an international digital ... Allen brings over 20 years experience in healthcare information ... companies including Dell Services Healthcare, Medsphere Systems and McKesson. ... fit for accomplishing the goals Optimal Medicine had for ...
(Date:3/31/2015)... HOUSTON, TX and VANCOUVER ... or the "Company") (TSX-V: EPI) announced today that it ... in the US an Investigation New Drug ("IND") application ... in prostate cancer patients.  Approval of the IND application ... testing of EPI-506 in the US.  ...
Breaking Biology Technology:Forensic Technologies and Services - Global Strategic Business Report 2015-2020: Rise in Terrorist Bombings Sharpens the Business Case for Explosives Forensics 2Forensic Technologies and Services - Global Strategic Business Report 2015-2020: Rise in Terrorist Bombings Sharpens the Business Case for Explosives Forensics 3Forensic Technologies and Services - Global Strategic Business Report 2015-2020: Rise in Terrorist Bombings Sharpens the Business Case for Explosives Forensics 4Forensic Technologies and Services - Global Strategic Business Report 2015-2020: Rise in Terrorist Bombings Sharpens the Business Case for Explosives Forensics 5Forensic Technologies and Services - Global Strategic Business Report 2015-2020: Rise in Terrorist Bombings Sharpens the Business Case for Explosives Forensics 6Forensic Technologies and Services - Global Strategic Business Report 2015-2020: Rise in Terrorist Bombings Sharpens the Business Case for Explosives Forensics 7Chardan Capital Issues Industry Note Covering Spherix 2Chardan Capital Issues Industry Note Covering Spherix 3Slone Partners Fills Head of Sales at Optimal Medicine 2ESSA Pharma Inc. Announces Filing of Investigational New Drug Application for EPI-506 2ESSA Pharma Inc. Announces Filing of Investigational New Drug Application for EPI-506 3ESSA Pharma Inc. Announces Filing of Investigational New Drug Application for EPI-506 4
... Claire, Wis. A team of Chippewa Valley representatives hope ... Twin Cities this week at the largest medical device ... & Manufacturing tradeshow at the Minneapolis Convention Center on ... 7,000 medical equipment and pharmaceutical company executives. , ,The ...
... The SBC Foundation , the philanthropic ... in SBC Excelerator technology grants to eight local nonprofit ... Excelerator is a major philanthropic initiative that connects the ... families, to important community resources. The program also empowers ...
... City Mayor Rudolph Giuliani will keynote RedShift 2006 ... and logistics industry summit at the Westin La Paloma ... , ,Giuliani will discuss how leaders at all ... corporate and organizational cultures. , ,RedPrairie provides industry-tailored supply-chain ...
Cached Biology Technology:Chippewa Valley reps hope to score at Twin Cities tradeshow 2SBC foundation gives Excelerator grants to local nonprofits 2SBC foundation gives Excelerator grants to local nonprofits 3SBC foundation gives Excelerator grants to local nonprofits 4
Anti-human VEGFR-1/Flt-1, clone Flt-1/EWI, Monoclonal Antibody...
... adds two new Stem Cell Antibody Panels ... products. The Human Embryonic Stem Cell Marker ... antibodies against: alkaline phosphatase, Nanog, Oct-3/4, SSEA-1 ... Marker Antibody Panel Plus (Catalog # SC009) ...
Request Info...
... Platypus Contact Printing Kit contains choice of Printing Surface ... Gold over Ti adhesion layer, 1 silicon wafer coated ... or 3 plain glass slides), PDMS Stamps (3 PDMS ... squares or 100 um x 10 mm or 200 ...
Biology Products: