Navigation Links
TGen and Scottsdale Healthcare launch Phase I 'Thunder God vine' trial for cancer
Date:9/12/2013

SCOTTSDALE, Ariz. Sept. 12, 2013 Taking a page from Chinese herbal medicine, Scottsdale Healthcare and the Translational Genomics Research Institute (TGen) today initiated the first-in-human clinical trial for pancreatic cancer patients using a compound derived from a plant known as "Thunder God vine."

The first patient to participate in this clinical trial received treatment today at Scottsdale Healthcare's Virginia G. Piper Cancer Center Clinical Trials, a partnership of Scottsdale Healthcare and TGen.

The Thunder God vine (Tripterygium wilfordii), also known as lei gong teng, is native to China, Japan and Korea. Traditional Chinese medicine has used the vine for more than 2,000 years as a treatment for everything from fever to inflammation and autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis.

A chemical compound called triptolide is among the more than 100 bioactive ingredients derived from the Thunder God vine. Preclinical studies showed a pharmaceutical version of triptolide called Minnelide proved effective against pancreatic cancer cells, according to a study by Dr. Ashok K. Saluja, Professor and Vice-Chair, Department of Surgery, University of Minnesota and Chief Scientific Officer and Co-Founder of Minneamrita Therapeutics LLC, published in the journal Science Translational Medicine.

The U.S. Food and Drug Administration (FDA) recently approved use of the compound Minnelide for a clinical trial of gastrointestinal cancer patients including pancreatic cancer.

"We have known for years about the potential beneficial use of Thunder God vine, but only recently with the advent of Minnelide have we created a form of triptolide that can be easily administered to patients," said Dr. Mohana R. Velagapudi, Chief Executive Officer and Co-Founder of Minneamrita Therapeutics LLC, the trials sponsor. "This clinical trial will hopefully provide the proof of concept so patients beyond the
'/>"/>

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. TGen, Scottsdale Healthcare study shows drug combination extends pancreatic cancer patient survival
2. NIH program explores the use of genomic sequencing in newborn healthcare
3. Notre Dame researchers develop system that uses a big data approach to personalized healthcare
4. Gilde Healthcare III Portfolio Company Definiens Establishes Advisory Board
5. Nurses at forefront of genomics in healthcare
6. Mount Sinai grad student, 25, named to Forbes 30 Under 30 in Science and Healthcare
7. BUSM/VA Boston Healthcare System investigators identify new gene linked to PTSD
8. Pilot Results Move GHX Closer to Delivery of Healthcare Industrys First Implantable Device Supply Chain Solution
9. VTT and GE Healthcare developing novel biomarkers to predict Alzheimers disease
10. BGI, GE Healthcare team up on pioneering stem cell science projects
11. Premier Healthcare Renews Supplier Agreement with Masimo
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2015)... NEW YORK , April 14, 2015 /PRNewswire/ ... Fast IDentity Online (FIDO ® ) Alliance tm ... standards-based specifications. FIDO members commit to share technology ... authentication methods that are interoperable, more secure and ... specifications enable biometric identity verification that protects sensitive ...
(Date:4/13/2015)... -- higi, a leading cloud-based consumer engagement platform that provides ... their communities around health and wellness, announced today the ... ... convenient vehicle to receive validated health information from consumers. ... API will allow higi,s trusted partners, on a user ...
(Date:4/8/2015)... CHARLOTTE, N.C. , April 8, 2015 /PRNewswire/ ... technology solutions and services, and Morpho, a leading ... in partnership to produce the market,s most advanced ... Infinisource,s iSolved NXG time clock is setting ... attendance and labor data for the small and ...
Breaking Biology News(10 mins):HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3
... This release is available in Spanish . ... and the onset of depressive disorders is not new in the ... the brain mechanism by which diet can condition mental health to ... at the Faculty of Medicine and Odontology of the University of ...
... JOLLA, CA-The Salk Institute has been awarded a $2.3 ... (CIRM) for translational research focusing on developing a novel ... research will concentrate on studying human induced pluripotent stem ... to replicate the disorder in the lab and investigate ...
... ISRAEL, February 4, 2011 Ben-Gurion University of the ... Ilse Katz Institute for Nanoscale Science and Technology, has ... Scientific Research. Dr. Mokari received the Prize for ... applications. ,Dr. Mokari is a senior lecturer ...
Cached Biology News:Scientific research reveals brain alterations linking omega 3 deficit with depression 2Scientific research reveals brain alterations linking omega 3 deficit with depression 3Stem cell leader awarded $2.3 million grant for Parkinson's 2
(Date:5/22/2015)... Lawrence, MA (PRWEB) May 22, 2015 ... that the U.S. Department of Agriculture (USDA), Grain ... a five year contract to Charm Sciences to ... Aflatoxin Quantitative Test (water-based) and ROSA FAST Aflatoxin ... WET-S5 Aflatoxin Quantitative Test uses Water Extraction ...
(Date:5/21/2015)... Specialty Pharmacy Times has completed ... to BPA Worldwide as a business publication member. ... data for Specialty Pharmacy Times based on business/distribution, ... a member of BPA Worldwide, Specialty Pharmacy Times ... with the most reliable, unequaled data,” said Chris ...
(Date:5/21/2015)... 2015 Imagine being able to ... those of others. Being able to read faces and ... people to anticipate their thoughts and actions like never ... feelings to create unique abstract paintings and video, or, ... inside a first-person-shooter as it creates action, dialog, and ...
(Date:5/21/2015)... , May 20, 2015 Research and ... the addition of the "2015 Global Survey ... their offering. The primary goal of ... flow cytometry instruments and reagents. Key information the ... the selection of flow cytometers, predominantly used applications ...
Breaking Biology Technology:USDA-GIPSA (FGIS) Awards 5 Year Contract for Aflatoxin Tests to Charm Sciences 2Specialty Pharmacy Times Joins BPA Worldwide 25 Days to Meet ARGUS - The World's First Contactless Emotions Scanner 2Global Survey on Flow Cytometry Adoption Trends 2015 2
... GROUNDBREAKING RESEARCH ON,ALZHEIMER,S DISEASE, MEMORY AND AGING, ... the new,$30 million Blanchette Rockefeller Neurosciences Institute ... West Virginia University and founded,in honor of ... host to,prominent international scientists who have achieved ...
... Agreement Signed in Third Quarter of 2008 Expands ... Application of Cutting-Edge Influenza Vaccine Technology, GAITHERSBURG, ... has licensed its proprietary reverse genetics intellectual property,to ... support,the development and construction of new vaccine strains ...
... TEMPE, Ariz., Oct. 16 A team of ... novel quantitative mass,spectrometry immunoassay for the detection of ... online on Oct. 14 in the journal of,Circulation: ... in Fremont, Christ Hospital in Cincinnati, and Medivation ...
Cached Biology Technology:Blanchette Rockefeller Neurosciences Institute Hosts First-Ever International Forum on Memory and Memory Disorders and Dedicates New $30 Million Research Facility 2Blanchette Rockefeller Neurosciences Institute Hosts First-Ever International Forum on Memory and Memory Disorders and Dedicates New $30 Million Research Facility 3Blanchette Rockefeller Neurosciences Institute Hosts First-Ever International Forum on Memory and Memory Disorders and Dedicates New $30 Million Research Facility 4MedImmune Licenses Reverse Genetics Technology to Hungary's Omninvest for Use in Influenza Vaccine Development and Production 2Novel Mass Spectrometry-based Assay Reveals Degradation and Low Levels of Bioactive B-type Natriuretic Peptide (BNP) in Patients with Heart Failure 2
Anti-Human IFN-Gamma Receptor Chain 2 (beta chain) [CD119], Rabbit serum, NON-neutralizing polyclonal antibody...
AANAT [Arylalkylamine N-acetyltransferase; EC 2.3.1.87]...
Rac1/2/3 (L129) Antibody Shipping Temperature: HOT Storage Temperature: -20C...
Sheep polyclonal to EBNA 3B ( Abpromise for all tested applications). Antigen: Full length protein....
Biology Products: