Navigation Links
TB outbreaks could be 'solved' by DNA tracking
Date:9/3/2012

Reconstructing the spread of killer diseases such as tuberculosis (TB) from person to person using DNA sequencing quickly identifies the origin and movement of pathogens. This approach is directly informing public health strategies to control infectious disease outbreaks, says a scientist speaking at the Society for General Microbiology's Autumn Conference at the University of Warwick.

A team from the British Columbia Centre for Disease Control in Vancouver, Canada used whole-genome sequencing to analyse the bacterial DNA in samples from 36 of 41 infected individuals in a TB outbreak. They were able to track the pathogen's movements through the community in British Columbia, including where it started and who infected whom. From this they could identify key persons, places, and behaviours that contributed to the spread of disease. They showed how the social structure of a community contributed to the rapid spread of TB and that a rise in crack cocaine use in the area may have triggered the outbreak.

Earlier epidemiological tools analysed some - but not all - of the DNA in infected samples. This gave too little information to accurately reconstruct an outbreak and scientists could only make informed guesses at how a pathogen spread through a population. Lead researcher Dr Jennifer Gardy, speaking at the conference said, "'Solving' an outbreak - identifying the source of the disease and the underlying patterns of transmission - is the proverbial holy grail of epidemiology. Using whole-genome sequencing we are now able to act like field naturalists and observe how pathogens behave out in the wild. We can see where outbreaks start and how they spread. This level of insight has never been seen before and it promises to change the way we do public heath outbreak investigations."

The group is currently applying the same reconstruction technique to a different TB outbreak in a different social setting. "We are discovering how important locati
'/>"/>

Contact: Laura Udakis
l.udakis@sgm.ac.uk
44-079-908-26696
Society for General Microbiology
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Researchers use game to change how scientists study disease outbreaks
2. Coconut oil could combat tooth decay
3. Chilling methods could change meat tenderness
4. Viruses could be the key to healthy corals
5. Early activation of immune response could lead to better vaccines
6. Computer viruses could take a lesson from showy peacocks
7. Collagen-seeking synthetic protein could lead doctors to tumor locations
8. Climate change could increase levels of avian influenza in wild birds
9. Manipulating the microbiome could help manage weight
10. U of M researchers: Newly discovered genetic markers could signal colon cancer development
11. Farmer-led irrigation schemes could alter food security in sub-Saharan Africa, South Asia
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
TB outbreaks could be 'solved' by DNA tracking
(Date:7/23/2014)... New Rochelle, NY -- The potential for clinical ... for transplant-based therapeutic strategies has previously been hindered ... the development of tumors. The ability to use ... for the treatment of heart disease, specifically acute ... Stem Cells and Development , a peer-reviewed ...
(Date:7/23/2014)... BCC Research ( ... MARKETS AND TECHNOLOGIES FOR SENSORS , the global market ... to nearly $154.4 billion by 2020, with a five-year ... flow, and level sensors segment is moving at a ... ) , Sensors have become indispensable to ...
(Date:7/23/2014)... . , Animals ... which might be very different from ours. Some bird ... sunlight in the atmosphere to calibrate their orientation systems. ... in Seewiesen, Germany, and Queen,s University Belfast have discovered ... the greater mouse-eared bat, has the capability to orient ...
Breaking Biology News(10 mins):Global Market for Sensors to Reach Nearly $154.4 Billion in 2020; Image Sensors Moving at 11.7% 2Global Market for Sensors to Reach Nearly $154.4 Billion in 2020; Image Sensors Moving at 11.7% 3Bats use the evening sky's polarization pattern for orientation 2
... has uncovered a protein that plays a vital role in ... in improving the production and quality of crops and biofuels. ... PNAS . The team included researchers from Dartmouth, ... Plant roots use their endodermis, or inner skin, as a ...
... Frederick will present new research at the 108th Annual ... and women,s beliefs about who should pay for dates ... expenses. The paper, Who Pays for Dates? Following versus ... than 17,000 participants; a quarter of whom also provided ...
... Vision licensee, Theresa Ayers , has added a second location ... Ronald Ayers , the husband-and-wife team assumed ownership last month ... Theresa Ayers has been with Pearle Vision, one of ... for more than three decades. She began her career working for ...
Cached Biology News:Research on which gender pays for dates shows change and resistance from convention 2Local Pearle Vision Licensee Adds Second Center In Canton, Ohio 2Local Pearle Vision Licensee Adds Second Center In Canton, Ohio 3Local Pearle Vision Licensee Adds Second Center In Canton, Ohio 4Local Pearle Vision Licensee Adds Second Center In Canton, Ohio 5
(Date:7/23/2014)... 23, 2014  Having the right people at the ... accelerating business growth and achieving clinical and operational goals. ... Leadership Summit, July 20-22, 2014, in San ... executives and healthcare experts discussing how partnerships have positively ... President & Chief Executive Officer of Cape Regional Medical ...
(Date:7/23/2014)... DES MOINES, Iowa (PRWEB) July 23, 2014 ... will join the business as vice president of Agricultural ... from Mendel Biotechnology where he served most recently as ... brings extensive biotechnology and business leadership in the seed ... DuPont Pioneer,” said Paul E. Schickler , president ...
(Date:7/23/2014)... 23, 2014  GrowBLOX Sciences, Inc. (OTCQB: GBLX), a medical ... filing for two medical marijuana dispensary locations in ... to the Clark County, Nevada dispensary ... as previously announced.  GrowBLOX Sciences, CEO Craig ... new applications for dispensaries in the City of ...
(Date:7/23/2014)... (PRWEB) July 23, 2014 OncLive® ... Cancer Center has joined its Strategic Alliance Partnership ... Alliance Partnership program, UNC Lineberger will have the ... raise awareness of its cutting-edge research initiatives, community-directed ... UNC Lineberger will work with OncLive to educate ...
Breaking Biology Technology:MSC and Cape Regional Medical Center Partner to Improve Cost, Quality and Outcomes 2DuPont Pioneer Names Neal Gutterson to Lead Agricultural Biotechnology 2DuPont Pioneer Names Neal Gutterson to Lead Agricultural Biotechnology 3GrowBLOX Sciences, Inc. Files for Two Additional Medical Marijuana Dispensaries in Las Vegas 2GrowBLOX Sciences, Inc. Files for Two Additional Medical Marijuana Dispensaries in Las Vegas 3OncLive Expands Its Strategic Alliance Partnership Program With the Addition of UNC Lineberger Comprehensive Cancer Center 2OncLive Expands Its Strategic Alliance Partnership Program With the Addition of UNC Lineberger Comprehensive Cancer Center 3
... , SAN FRANCISCO, Dec. 1 Medizone International, ... tests involving its proprietary AsepticSure(TM) technology, it continues to ... very different spore forming bacteria, Claustridium difficile and Bacillis ... potent sporicidal technology. "The implications of a 6.7 log ...
... ... comprehensive training programs, including biomedical repair technologies. Their shared efforts will begin in 2010 ... ... the recent signing of a Memorandum of Understanding, Mercy Ships and MediSend International have ...
... Cambridge, Mass November 30, 2009 An ... Photonics, and ETH Zrich have demonstrated compact, multibeam, ... of the light spectrum (infrared). By contrast, typical ... well-defined wavelength. The innovative multibeam lasers have potential ...
Cached Biology Technology:Medizone International Takes Aim at the Bioterrorism Countermeasures Arena 2Mercy Ships and MediSend International Partner to Deliver Hope and Healing 2Mercy Ships and MediSend International Partner to Deliver Hope and Healing 3Scientists demonstrate multibeam, multi-functional lasers 2
... of 2D polyacrylamide gel electrophoresis (2D-PAGE) with ... a core technology platform for proteomic analysis. ... complex samples limited only in the dynamic ... large proteins. Quantitative image based analysis of ...
...
... use in Refrigerated Vapor Trap Models RVT100, ... (UVS) Models UVS400, UVS400A and UVS800DDA., A ... for use for temperatures ranging from -105 ... thermal stability and does not evaporate. Far ...
... 10X Automation Buffer is a concentrated formulation ... autostainers employing capillary action technology, as well ... in collaboration with David Brigati M.D., Department ... OK. This buffer is recommended for all ...
Biology Products: