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Study suggests weight loss from gastric bypass may be partly due to dietary fat aversion
Date:7/27/2011

e same preference for all concentrations of the fat emulsion when exposed to these liquids for only brief amounts of time. However, those that had a small amount of corn oil infused into their stomach were more likely to avoid the saccharine-flavored water than those infused with saline, much like those given the lithium chloride injections. Levels of GLP-1 were significantly higher in the Roux-en-Y rats compared to the non-bypass animals.

Importance of the Findings

The results suggest that people and animals who undergo Roux-en-Y gastric bypass decrease their consumption of both solid and liquid dietary fat, possibly helping people stick to a healthier diet. This avoidance does not appear to be triggered by taste alone, but can be influenced by the effects after ingestion. The hormone GLP-1 might be partly responsible for these effects.

"These findings suggest that changes in fat preference may contribute to long-term maintained weight loss after gastric bypass," the authors wrote. "By elucidating the mechanisms by which obesity surgery reduces the consumption of high fat foods, new surgical and non-surgical therapies could be developed that mimic these mechanisms to offer safe and effective weight loss."


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Contact: Donna Krupa
dkrupa@the-aps.org
301-634-7209
American Physiological Society
Source:Eurekalert

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