Navigation Links
Study shows link between alcohol consumption and hiv disease progression
Date:8/20/2007

(Boston) Researchers from Boston University School of Medicine (BUSM) have found a link between alcohol consumption and HIV disease progression in HIV-infected persons. The study appears online in the August issue of the Journal of Acquired Immune Deficiency Syndromes.

Alcohol use is common among HIV-infected persons, and its impact on HIV disease progression has been examined in in-vitro, animal and human studies. Alcohol may adversely affect immunologic function in HIV-infected persons by various mechanisms, including increased HIV replication in lymphocytes.

Researchers assessed CD4 cell counts, HIV RNA levels [viral load], and alcohol consumption in 595 HIV-infected persons with alcohol problems. The relation of HIV disease progression to alcohol consumption was studied using longitudinal regression models controlling for known prognostic factors, including adherence and depressive symptoms, and stratified by antiretroviral therapy (ART) use. Among subjects who were not on ART, heavy alcohol consumption was associated with a lower CD4 cell count. Among subjects who were on ART, heavy alcohol consumption was not associated with a lower CD4 cell count or higher HIV viral load.

Alcohol use in patients with a prevalent disease such as HIV, can have important public health consequences, said lead author Jeffrey Samet, MD, MPH, a professor of medicine at BUSM and chief of General Internal Medicine at Boston Medical Center. HIV-infected persons who drink alcohol heavily and are not on ART might decrease their risk of disease progression if they abstain from alcohol use.

Researchers further noted that there is extensive evidence about the efficacy of a brief intervention for unhealthy alcohol use in nondependent drinkers in medical settings and of the efficacy of psychosocial and pharmacologic treatments for alcohol dependence. Although limited evidence demonstrates the effectiveness of intervention for alcohol problems specifically in people with HIV, its implementation among HIV-infected populations seems to be a worthwhile goal, according to senior author Richard Saitz, MD, MPH, professor of medicine at BUSM, director of the Clinical Addiction Research and Education Unit at Boston Medical Center, and associate director of the Boston University School of Public Health Youth Alcohol Prevention Center.


'/>"/>

Contact: Michelle Roberts
michelle.roberts@bmc.org
617-638-8491
Boston University
Source:Eurekalert

Related biology news :

1. Bioartificial kidney under study at MCG
2. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
3. W.M. Keck Foundation funds study of friendly microbes
4. Yellowstone microbes fueled by hydrogen, according to U. of Colorado study
5. Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs
6. UCLA Study Shows One-Third of Drug Ads in Medical Journals Do Not Contain References Supporting Medical Claims
7. Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
8. Study Links Ebola Outbreaks To Animal Carcasses
9. Genome-wide mouse study yields link to human leukemia
10. Breakthrough Microarray-based Technology for the Study of Cancer
11. NYU Study Reveals How Brains Immune System Fights Viral Encephalitis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... 24, 2017 Janice Kephart , ... Identity Strategy Partners, LLP (IdSP) , today issues ... President Trump,s March 6, 2017 Executive Order: ... vetting can be instilled with greater confidence, enabling ... all refugee applications are suspended by until at ...
(Date:4/13/2017)... Calif. , April 13, 2017 UBM,s ... York will feature emerging and evolving technology ... Both Innovation Summits will run alongside the expo portion ... speaker sessions, panels and demonstrations focused on trending topics ... largest advanced design and manufacturing event will take place ...
(Date:4/11/2017)... BROOKLYN, N.Y. , April 11, 2017 /PRNewswire-USNewswire/ ... identical fingerprints, but researchers at the New York ... University College of Engineering have found that partial ... fingerprint-based security systems used in mobile phones and ... previously thought. The vulnerability lies in ...
Breaking Biology News(10 mins):
(Date:9/20/2017)... ... 20, 2017 , ... Proscia Inc. , a data ... of whole slide imaging solutions, are hosting a pre-conference workshop at the ... a Best-in-Class Strategy for Digital Pathology,” will feature Proscia CEO, David West Jr., ...
(Date:9/20/2017)... ... September 20, 2017 , ... RoviSys, a leading ... today the opening of an office in Taipei, Taiwan. This new location allows ... while developing new relationships in the region. Located in the Neihu area of ...
(Date:9/19/2017)... Poway, CA (PRWEB) , ... September 19, 2017 , ... VetStem Biopharma ’s CEO ... H. Riordan PA, PhD in Riordan’s new book "Stem Cell Therapy: A Rising Tide". ... past 14 years. They bonded over an interest in the potential of stem cell ...
(Date:9/19/2017)... ... September 19, 2017 , ... Avomeen Analytical Services, ... of its 2017 Science Student Award. The scholarship program is dedicated to helping ... service defray the costs of obtaining their science education. , Avomeen began the ...
Breaking Biology Technology: