Navigation Links
Study quantifies the size of holes antibacterials create in cell walls to kill bacteria
Date:1/10/2013

burst. To test the theory, Daniel Nelson, an assistant professor at the University of Maryland, used transmission electron microscopy images to measure the size of holes created in lysed Streptococcus pyogenes bacteria cells following PlyC exposure.

Nelson found holes in the lysed bacteria cells that ranged in diameter from 22 to 180 nanometers, with a mean diameter of 68 nanometers. These experimental measurements agreed with the researchers' theoretical prediction of critical hole sizes that cause bacterial cell death.

According to the researchers, their theoretical model is the first to consider the effects of cell wall thickness on lysis.

"Because lysis events occur most often at thinner points in the cell wall, cell wall thickness may play a role in suppressing lysis by serving as a buffer against the formation of large holes," said Mitchell.

The combination of theory and experiments used in this study provided insights into the effect of defects on a cell's viability and the mechanisms used by enzymes to disrupt homeostasis and cause bacteria cell death. To further understand the mechanisms behind enzyme-induced lysis, the researchers plan to measure membrane dynamics as a function of hole geometry in the future.


'/>"/>

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. New study identifies significance of co-infection in disease control
2. Study finds Jurassic ecosystems were similar to modern: Animals flourish among lush plants
3. Major cuts to surging CO2 emissions are needed now, not down the road, study finds
4. International study suggests human genes influence gut microbial composition
5. New study defines the long-sought structure of a protein necessary for cell-cell interaction
6. Bering Sea study finds prey density more important to predators than biomass
7. Big brains are pricey, guppy study shows
8. Hebrew University study finds key mechanism in calcium regulation
9. New study documents the natural relationship between CO2 concentrations and sea level
10. Stowers study hints that stem cells prepare for maturity much earlier than anticipated
11. Birdsong study pecks theory that music is uniquely human
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study quantifies the size of holes antibacterials create in cell walls to kill bacteria
(Date:4/17/2014)... credit-card-sized anthrax detection cartridge developed at Sandia National Laboratories ... safer, easier, faster and cheaper. , Bacillus ... found in soils all over the world and can ... and animals. The bacteria can survive in harsh conditions ... may occur through skin contact, inhalation of spores ...
(Date:4/17/2014)... German . ... also provide us with a continuous stream of information about ... sit still in a car the world glides by ... Seemingly without effort, our brain calculates self-motion from this "optic ... a steady gaze during our own movements. Together with biologists ...
(Date:4/17/2014)... bone marrow need to produce hydrogen sulfide in order ... a new study from the Center for Craniofacial Molecular ... USC. , Professor Songtao Shi, principal investigator on the ... the cells governs the flow of calcium ions. The ... results in osteogenesis, or the creation of new bone ...
Breaking Biology News(10 mins):Pocket-sized anthrax detector aids global agriculture 2Pocket-sized anthrax detector aids global agriculture 3How vision makes sure that little fish do not get carried away 2How vision makes sure that little fish do not get carried away 3How vision makes sure that little fish do not get carried away 4
... HOLE, MADr. Bruce J. Peterson, a senior scholar at ... the Association for the Sciences of Limnology and Oceanography ... Achievement Award. The award honors the career achievements of ... importance and long-term influence. Dr. Peterson is being honored ...
... breakthrough at the University of Huddersfield has received extra stimulus ... major conference in Australia. Mari L. Uchimoto, from Montana, ... member of its Forensic Genetics Research Group and supervised by ... a team working on the use of microRNA analysis in ...
... the Norwegian University of Science and Technology in Trondheim have ... of winter conditions for fish in streams and rivers in ... journal BioScience . It is well known that ... in streams and rivers. It is reasonable to assume that ...
Cached Biology News:MBL scientist Bruce Peterson wins ASLO Lifetime Achievement Award 2MBL scientist Bruce Peterson wins ASLO Lifetime Achievement Award 3Mari's presentation tops ANZFSS International Symposium 2Extreme winters impact fish negatively 2
(Date:1/15/2014)... 2014 AudioNotch is the internet's leading ... the treatment of tinnitus. Patients listen to sound therapy ... a period of weeks to months, their tinnitus volume decreases. ... forms: Notched Music and Notched White Noise. Now, AudioNotch is ...
(Date:1/14/2014)... 2014 Carahsoft and CDS Federal Services ... 2014 at 2pm EST (11am PST), “Natural Language Processing: ... on how technology can turn raw, heterogeneous data into ... agencies. The online webinar will last approximately one hour. ...
(Date:1/14/2014)... BURLINGAME, Calif. , Jan. 14, 2014 As pet owners ... no doubt many of them wrote: "Take better care of my ... and even designer clothes and top-brand carrying cases to take the ... Pet parents might also feel compelled to buy some pricey toys ...
(Date:1/14/2014)... and BETHESDA, Md. , Jan. 14, ... with two institutes from the National Institutes of Health ... bringing safer, more effective treatments to patients on a ... for Advancing Translational Sciences (NCATS) and the National Eye ...
Breaking Biology Technology:Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2Organovo Announces Collaboration with National Institutes of Health 2Organovo Announces Collaboration with National Institutes of Health 3
... SAN DIEGO, Jan. 19, 2011 LifeVantage Corporation ... science-based solutions to oxidative stress, announced preliminary unaudited net revenue ... net revenue of approximately $7.4 million for the three month ... approximately $1.0 million or 15% over net revenue of $6.4 ...
... Inc. (OTC Bulletin Board: RGIN ) a ... regenerative cell therapies to restore the health of damaged ... feedback from attendees following their presentations at the OneMedForum ... conference was CEO Randall McCoy and senior Board Members ...
... This release is available in German . ... Ralph G. Nuzzo paved the way for use of the ... without that innovation. Professor Nuzzo is now honored with the ... includes guest visits to the Institute of Functional Interfaces (IFG) ...
Cached Biology Technology:LifeVantage Announces Preliminary Unaudited Second Quarter 2011 Results 2LifeVantage Announces Preliminary Unaudited Second Quarter 2011 Results 3Regenicin Receives Positive Feedback at OneMedForum Conference 2New impulses for surface research 2