Navigation Links
Study provides explanation for connection between low birth weight and obesity later in life

Providing further understanding of the link between low birth weights and obesity later in life, researchers found nutritionally deprived newborns are "programmed" to eat more because they develop less neurons in the region of the brain that controls food intake, according to an article published today in the journal, Brain Research.

The study by a team of researchers at Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) suggests that overeating is programmed at the level of stem cells before birth when the mother has poor or inadequate nutrition.

Using an animal model, the researchers found less division and differentiation of the neural stem cells of a newborn with low birth weight as compared to normal birth weight. Previous studies have found a small size at birth followed by accelerated "catch-up" growth is associated with an increased risk of adult obesity, cardiovascular disease, type 2 diabetes, hypertension and osteoporosis.

"This study demonstrates the importance of maternal nutrition and health in reducing obesity," said Dr. Mina Desai, an LA BioMed principal investigator and corresponding author of the new study. "Obesity and its related diseases are the leading cause of death in our society, yet we have few effective strategies for prevention or treatment. These studies suggest maternal nutrition could play a critical role in preventing obesity and related disease."

In addition to obesity, the findings of altered brain (neural stem cells) development suggest that fetal growth restriction may be associated with cognitive and/or behavioral alterations. Importantly, the study offers potential opportunities for prevention and treatment for obesity and other related disorders. In addition to Dr. Desai, LA BioMed investigators Tie Li and Michael G. Ross participated in the study.

More than 60% of American adults are overweight and more than 1 in 5 are obese. Obesity is a serious health concern for children and adolescents, as well. About 17 percent of children and adolescents ages 2-19 years are obese.


Contact: Laura Mecoy
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed)

Related biology news :

1. New UF study shows some sharks follow mental map to navigate seas
2. Study shows how plants sort and eliminate genes over millennia
3. MBARI and Monterey Bay National Marine Sanctuary to study effects of shipping containers lost at sea
4. Rensselaer professor utilizing New York state grant to study adult stem cells
5. Study analyzes role of PARP enzyme in eukaryotes
6. Fossil bird study describes ripple effect of extinction in animal kingdom
7. University of Missouri researcher study provides insight into how corn makes hormones
8. Rainwater harvest study finds roofing material affects water quality
9. A study reveals the keys to the locomotion of snails
10. Pathology study tracks uterine changes with mifepristone
11. David and Goliath viruses shed light on the origin of jumping genes: UBC study
Post Your Comments:
Related Image:
Study provides explanation for connection between low birth weight and obesity later in life
(Date:4/18/2017)... Calif. , April 18, 2017  Socionext Inc., a global ... of a media edge server, the M820, which features the company,s ... recognition software provided by Tera Probe, Inc., will be showcased during ... at the NAB show at the Las Vegas ... ...
(Date:4/11/2017)... April 11, 2017 Crossmatch®, a globally-recognized ... solutions, today announced that it has been awarded ... Projects Activity (IARPA) to develop next-generation Presentation Attack ... "Innovation has been a driving force within ... will allow us to innovate and develop new ...
(Date:4/6/2017)... LONDON , April 6, 2017 ... Control, RFID, ANPR, Document Readers, by End-Use (Transportation & ... Energy Facility, Oil, Gas & Fossil Generation Facility, Nuclear ... Healthcare, Educational, Other) Are you looking for ... Authentication sector? ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... 2017 , ... They call it the “hairy ball.” It’s ... of a system of linkages and connections so complex and dense that “it ... science at Worcester Polytechnic Institute (WPI) and director of the university’s bioinformatics and ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... partners with the pharmaceutical and biotechnology industries to improve patient outcomes and quality ... Several trends in analytical testing are being attributed to new regulatory requirements for ...
(Date:10/11/2017)... ... October 11, 2017 , ... ComplianceOnline’s Medical Device Summit is back for its ... 2018 in San Francisco, CA. The Summit brings together current and former FDA office ... directors and government officials from around the world to address key issues in device ...
(Date:10/11/2017)... ... October 11, 2017 , ... A new study ... in frozen and fresh in vitro fertilization (IVF) transfer cycles. The ... IVF success. , After comparing the results from the fresh and frozen transfer ...
Breaking Biology Technology: