Navigation Links
Study of twins discovers gene mutation linked to short sleep duration
Date:7/31/2014

DARIEN, IL Researchers who studied 100 twin pairs have identified a gene mutation that may allow the carrier to function normally on less than six hours of sleep per night. The genetic variant also appears to provide greater resistance to the effects of sleep deprivation.

Results show that a participant with p.Tyr362His a variant of the BHLHE41 gene had an average nightly sleep duration of only five hours, which was more than one hour shorter than the non-carrier twin, who slept for about six hours and five minutes per night. The twin with the gene mutation also had 40 percent fewer average lapses of performance during 38 hours without sleep and required less recovery sleep afterward sleeping only eight hours after the period of extended sleep deprivation compared with his twin brother, who slept for 9.5 hours.

According to the authors, this is only the second study to link a mutation of the BHLHE41 gene also known as DEC2 - to short sleep duration. The study provides new insights into the genetic basis of short sleep in humans and the molecular mechanisms involved in setting the duration of sleep that individuals need.

"This work provides an important second gene variant associated with sleep deprivation and for the first time shows the role of BHLHE41 in resistance to sleep deprivation in humans," said lead author Renata Pellegrino, PhD, senior research associate in the Center for Applied Genomics at The Children's Hospital of Philadelphia. "The mutation was associated with resistance to the neurobehavioral effects of sleep deprivation."

Study results are published in the Aug. 1 issue of the journal Sleep.

The study group comprised 100 twin pairs 59 monozygotic pairs and 41 dizygotic pairs who were recruited at the University of Pennsylvania. All twin pairs were the same sex and were healthy with no chronic conditions. Nightly sleep duration was measured at home by actigraphy for seven to eight ni
'/>"/>

Contact: Lynn Celmer
lcelmer@aasmnet.org
630-737-9700
American Academy of Sleep Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. Study finds benefits to burning Flint Hills prairie in fall and winter
2. UT Dallas study reveals effect of loud noises on brain
3. New international tree nut council study looks at nuts, diabetes and metabolic syndrome
4. Study: Marine pest provides advances in maritime anti-fouling and biomedicine
5. Healthy lifestyle may buffer against stress-related cell aging, study says
6. Study suggests disruptive effects of anesthesia on brain cell connections are temporary
7. Study finds Europes habitat and wildlife is vulnerable to climate change
8. Dinosaurs fell victim to perfect storm of events, study shows
9. Study: Climate change and air pollution will combine to curb food supplies
10. First national study finds trees saving lives, reducing respiratory problems
11. New study draws links between wildlife loss and social conflicts
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/4/2014)... SALT LAKE CITY, Nov. 5, 2014 – University of ... uses enzymes to help jet fuel produce electricity without ... can be used to power portable electronics, off-grid power ... appears online today in the American Chemical Society journal ... into electricity through a chemical reaction between a fuel ...
(Date:11/4/2014)... , November 4, 2014   ... vertical market growth   Fuel3D , a ... closed a funding round totaling $6.4 million (£4 million). This ... funding secured earlier this year and paves the way for ... 2015. The funding round was led by Chimera ...
(Date:11/3/2014)... LOS ANGELES , Nov. 3, 2014 /PRNewswire/ ... California -based life sciences company focused on ... eTNS system for the treatment of neurological ... Institute of Industrial Property has issued a Notice ... The patent application is co-owned by NeuroSigma and ...
Breaking Biology News(10 mins):Jet-fueled electricity at room temperature 2Fuel3D Secures $6.4 Million in Expansion Funding 2Fuel3D Secures $6.4 Million in Expansion Funding 3NeuroSigma Receives Notice of Allowance from the Mexican Institute of Industrial Property Covering Subcutaneous Trigeminal Nerve Stimulation (sTNS) 2NeuroSigma Receives Notice of Allowance from the Mexican Institute of Industrial Property Covering Subcutaneous Trigeminal Nerve Stimulation (sTNS) 3
... 26 2012) Tufts University School of Engineering researchers ... that maintains the collagen,s natural strength and fiber structure, ... Collagen, the most abundant protein in the body, ... because it is biocompatible and biodegradable. Collagen is, however, ...
... cells, embryonic stem cells are by definition equipped to assume ... as an organism develops, stem cells must be ready at ... used to turn them into blood, brain, or kidney cells. ... Shilatifard, Ph.D., report in the December 27, 2012 online issue ...
... Second Life, female avatars expose substantially more skin than ... research published December 26 in the open access journal ... from Laval University, Canada. The human tendency ... cultural constraints, so measuring people,s propensity to reveal skin ...
Cached Biology News:Slice, stack, and roll: A new way to build collagen scaffolds 2Stowers study hints that stem cells prepare for maturity much earlier than anticipated 2Stowers study hints that stem cells prepare for maturity much earlier than anticipated 3
(Date:11/21/2014)... , November 21, 2014 , ... responsable comercial   Mariano Rodríguez es elegid ... KLOX está en marcha para comenzar de ... cura de heridas de reciente aprobación en Europa   , ... compañía") se complace al anunciar los siguientes nombramientos: ...
(Date:11/21/2014)... CA (PRWEB) November 20, 2014 Author ... Short Walk to the Other Side” published as ... “Award-Winning Finalist in the “Fiction: Short Story” category of ... Jeffrey Keen, President and CEO of USA Book News, ... mainstream and independent publishers, including Simon & Schuster, Penguin, ...
(Date:11/21/2014)... BlueInGreen, LLC ( BlueInGreen® ) and ... PCI, Inc., leading suppliers of ozone process technology ... to provide a new state-of-the-art ozone system for ... Wastewater Treatment. The new ozone disinfection system ... dissolution technology, Pinnacle Ozone’s industry leading Zenith™ ozone ...
(Date:11/21/2014)... , Nov. 20, 2014 Polaris Group ... dosed in its Phase 1 trial of ADI-PEG ... the treatment of malignant pleural mesothelioma (MPM) and ... conducting clinical trials on ADI-PEG 20, both as ... the treatment of several other indications, including breast ...
Breaking Biology Technology:KLOX Technologies anuncia sus nombramientos ejecutivos 2KLOX Technologies anuncia sus nombramientos ejecutivos 3KLOX Technologies anuncia sus nombramientos ejecutivos 4KLOX Technologies anuncia sus nombramientos ejecutivos 5Mystic Ink 's Short Story Collection “A Short Walk to the Other Side” Honoring Ray Bradbury Praised As Award-Winning Finalist In USA Best Book Awards 2Mystic Ink 's Short Story Collection “A Short Walk to the Other Side” Honoring Ray Bradbury Praised As Award-Winning Finalist In USA Best Book Awards 3Mystic Ink 's Short Story Collection “A Short Walk to the Other Side” Honoring Ray Bradbury Praised As Award-Winning Finalist In USA Best Book Awards 4City of Fayetteville Leads Nation with Innovative Ozone Technology 2City of Fayetteville Leads Nation with Innovative Ozone Technology 3City of Fayetteville Leads Nation with Innovative Ozone Technology 4Polaris Group Announces Treatment of First Patient in Phase 1 Study of ADI-PEG 20 plus Pemetrexed and Cisplatin in Malignant Pleural Mesothelioma And Non-Squamous Non-Small Cell Lung Carcinoma 2
... University of Warwick have found that tiny nanoparticles could ... of two non mixing liquids than previously believed. ... the uses of nanoparticles in living cells, polymer composites, ... are also working on ways of further artificially enhancing ...
... NEW YORK, Feb. 17 The following is from ... article, "Ruin Your Health With the Obama Stimulus Plan."I ... issue a correction. Mr. Olbermann charges that I, Betsy ... pharmaceutical industry, the biotech industry, the Hudson Institute, or ...
... Pa., Feb. 17 Environmental Tectonics Corporation,s (Amex: ... Division today announced the sale of two (2) BARA-MED(R) ... SC, USA.ETC is delighted to work with Oasis Hyperbarics, ... MD and Tim Osbon, MD. Oasis Hyperbarics is affiliated ...
Cached Biology Technology:Nanoparticles double their chances of getting into sticky situations 2Environmental Tectonics Corporation's BioMedical Division Announces Sale of Two Monoplace Hyperbaric Chambers 2Environmental Tectonics Corporation's BioMedical Division Announces Sale of Two Monoplace Hyperbaric Chambers 3Environmental Tectonics Corporation's BioMedical Division Announces Sale of Two Monoplace Hyperbaric Chambers 4
Rabbit polyclonal to JNK1 (phospho T183 + Y185) ( Abpromise for all tested applications). entrezGeneID: 5599 SwissProtID: P45983...
Cytofix Buffer 100 mls...
Perm/Wash Buffer 250 Tests...
The BD PhosFlow Fix Buffer I can be used for the simultaneous fixation and permeabilization of cells prior to intracellular staining. Applications: Intracellular Staining (Flow) Storage Temperature:...
Biology Products: