WASHINGTON, Aug. 15, 2007 A mysterious epidemic of thyroid disease among pet cats in the United States may be linked to exposure to dust shed from flame retardants in household carpeting, furniture, fabrics and pet food, scientists are reporting in a study scheduled for publication the Aug. 15 online issue of Environmental Science & Technology, a semi-monthly journal from the American Chemical Society, the worlds largest scientific society.
Janice A. Dye, DVM, Ph.D., at the U. S. Environmental Protection Agency in Research Triangle Park, N.C., and colleagues from there as well as Indiana University and the University of Georgia, report evidence linking the disease to exposure to environmental contaminants called polybrominated diphenyl ethers (PBDEs), which the researchers found to be elevated in blood samples of hyperthyroid cats. Their findings were based on analysis of blood samples from 23 pet cats, 11 of which had the disease, termed feline hyperthyroidism (FH). PBDE levels in the hyperthyroid cats were three times as high as those in younger, non-hyperthyroid cats.
Concerns about the possible health effects of PDBEs arose in the late 1990s, and studies have reported that PDBEs cause liver and nerve toxicity in animals. FH is one of the most common and deadly diseases in older cats, and indoor pets are thought to be most at-risk. For starters, cats ingest large amounts of PBDE-laden house dust that the researchers believe comes from consumer household products.
Dye, a toxicologist, began by hypothesizing that prolonged contact with certain polyurethane foams and components of carpet padding, furniture and mattresses would pose the greatest hazard for developing FH. In addition, the researchers suspected that diet might be another risk factor for developing FH. To see if a link existed, they analyzed PBDE content in several cat food brands.
Their analysis found that PBDE content of canned fish/seafood flavors, such as
|Contact: Michael Bernstein|
American Chemical Society