Navigation Links
Stem cell source an important factor, impacting ability to treat myocardial infarction
Date:2/13/2013

Putnam Valley, NY. (Feb. 13, 2013) When a research team from Denmark and Sweden compared the therapeutic capabilities of adipose-derived stem cells (ASCs) versus bone marrow-derived stem cells (BMSCs) obtained from a single 84 year-old male donor with ischemic coronary disease to regeneratively treat myocardial infarction in a rat model, they found that the ASCs preserved more cardiac function in the test rats while neither stem cell type induced myocardial angiogenesis (blood vessel growth.)

The study appears as an early e-publication for the journal Cell Transplantation, and is now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/pre-prints/ct0921rasmussen.

"Treatment of myocardial infarction with bone marrow-derived mesenchymal stem cells (BM-MSCs) and adipose-derived stem cells has shown promising results," said study co-author Dr. Trine Fink. "The transplantation of MSCs in treating myocardial infarction (MI) has been shown to improve left ventricular function in animal models. In this study, we compared the effects of adipose-derived stem cells and BMSCs from an elderly male suffering from coronary atherosclerosis when the donated cells were transplanted randomly, without the administration of immunosuppressant drugs, into two groups of adult rats modeled with MI."

The researchers noted that the age and health status of cell donors are important factors and that the impact of cell transplantation using cells from elderly patients with cardiac ischemia "needs to be elucidated."

The researchers found that ASCs ameliorated heart failure following MI in the group receiving ASCs while the group receiving the BMSCs received no similar benefit. They found that the BMSCs secreted a significantly larger amount of vascular endothelial growth factor, VEGF, than the ASCs, but that did not result
'/>"/>

Contact: Robert Miranda
cogcomm@aol.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology news :

1. Hastings Center resources chart progress in debate over medical research with animals
2. Nitrogen from pollution, natural sources causes growth of toxic algae, study finds
3. Marginal lands are prime fuel source for alternative energy
4. Elsevier launches new journal: Journal of Unconventional Oil and Gas Resources
5. The first genome sequence of Chinese plum provides important resource for fruit improvement
6. Soybeans a source of valuable chemical
7. Lyncean Technologies Inc. sells Compact Light Source to Munich biomedical-imaging research center
8. New test adds to scientists understanding of Earths history, resources
9. Stanford geoscientist cites critical need for basic research to unleash promising energy sources
10. Study IDs kerosene lamps as big source of black carbon
11. Water resources management and policy in a changing world: Where do we go from here?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2013)... 24, 2013 A frequently expressed concern in the ongoing ... fresh vegetables, especially those that are nutrient dense. ... and Beans Provide Most Nutrients Per Penny," published in ... are one of the best nutritional values in the ... per penny than most other raw vegetables and delivering ...
(Date:5/24/2013)... detection and destruction by the immune system. Stimulation of ... however, there are many factors that cause the immune ... immune cells that function to suppress the immune system ... Clinical Investigation , researchers led by Ronald Levy at ... tumors express proteins that can be targeted with therapeutic ...
(Date:5/24/2013)... against Alzheimer,s disease, scientists have focused among other factors ... After all, it is the accumulation of A-beta that causes ... point for the formation of A-beta is APP. Alessia Soldano ... the function of APPL the fruit-fly version of APP ... Alessia Soldano (VIB/KU Leuven): "We have discovered that APPL ensures ...
Breaking Biology News(10 mins):New research shows that potatoes provide one of the best nutritional values per penny 2A new strategy required in the search for Alzheimer's drugs? 2
... scientists start analyzing it), but it is fascinating. As we ... a sperm, a whole lot of cell division and growth, ... mix of genes from both parents. There are many startling ... and important is the transition from unfertilized egg to fertilized ...
... our planet, consisting of only DNA or RNA and a ... second most common type of organism. In our oceans they ... a better understanding of the structure and characteristics of these ... be able to determine their masses and how much these ...
... drug has been shown to improve blood flow in diseased ... attacks, a Monash University study published today reveals. , The ... in conjunction with Bayer Health Care, hopes to use the ... heart disease. , Dr. Harald Schmidt, Director of the Centre ...
Cached Biology News:Cracking the egg 2Weighty viruses 2Heart smart: new drug improves blood flow 2
(Date:5/23/2013)... , May 23, 2013  Rahal Letterman Lanigan ... human cord blood stem cell banking and therapeutics, announced ... the No. 16 Acorn Stairlifts Indy car driven by ... the remainder of the IZOD IndyCar 2013 season.   ... will work to support awareness of umbilical cord blood ...
(Date:5/23/2013)... Calif. , May 23, 2013 ... a strategic alliance with DAK Renewable Research to ... corn oil yield. VG Energy is a majority ... Pink: VGLS). VG Energy,s exclusively licensed ... increase the oil yield in plants, possessing a ...
(Date:5/23/2013)... , May 23, 2013 BioTrends Research ... advisory firms for specialized biopharmaceutical issues, finds that, ... infectious disease specialists reported that in the past ... intentionally delaying treatment) in anticipation of the next ... months ago, when only 6 percent reported that ...
(Date:5/23/2013)... 23, 2013 Northwest Biotherapeutics (NASDAQ: ... ® personalized immune therapies for solid tumor cancers, ... this year,s American Society Of Clinical Oncology (ASCO) meeting ... leadership role in immune therapy.  (Logo: ... is the pre-eminent conference focused on clinical treatment of ...
Breaking Biology Technology:StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 2StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 3VG Energy Enters into a Strategic Alliance with DAK Renewable Research for LipidMax Field Trials 2VG Energy Enters into a Strategic Alliance with DAK Renewable Research for LipidMax Field Trials 3The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 2The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 3NW Bio Exhibit at the Upcoming ASCO Meeting to Highlight its Leadership Role in Immune Therapy for Cancer 2NW Bio Exhibit at the Upcoming ASCO Meeting to Highlight its Leadership Role in Immune Therapy for Cancer 3
... which bounced to a near pinpoint landing inside a ... seven-month flight, promises a trove of new data about ... a UW-Madison professor of geology and geophysics who has ... Mars, expects the latest mission to add considerably to ...
... Wis. - GE Medical Systems and University Community Health ... based in Tampa, Florida have announced an agreement to build ... Medical Systems will be the technology provider for UCH's ... Southeast using advanced digital technology, when it opens in the ...
... has many great assets for building a thriving high technology ... at the University of Wisconsin-Madison . Yet we ... we have lacked one vital ingredient: venture capital to support ... ,According to the National Venture Capital Association , Wisconsin, ...
Cached Biology Technology:GE Medical Enables Digital Heart Hospital 2GE Medical Enables Digital Heart Hospital 3Wisconsins VC Challenge 2Wisconsins VC Challenge 3
... the ultimate in utility and flexibility press-to-seal ... the needs of the researcher. They are ... or as sheet material that can be ... isolators are autoclavable and non-cytotoxic and can ...
Argon Calibration Source...
SHEEP ANTI ESCHERICHIA COLI...
Recombinant Rat Leptin, CF...
Biology Products: