Navigation Links
Stem cell source an important factor, impacting ability to treat myocardial infarction
Date:2/13/2013

Putnam Valley, NY. (Feb. 13, 2013) When a research team from Denmark and Sweden compared the therapeutic capabilities of adipose-derived stem cells (ASCs) versus bone marrow-derived stem cells (BMSCs) obtained from a single 84 year-old male donor with ischemic coronary disease to regeneratively treat myocardial infarction in a rat model, they found that the ASCs preserved more cardiac function in the test rats while neither stem cell type induced myocardial angiogenesis (blood vessel growth.)

The study appears as an early e-publication for the journal Cell Transplantation, and is now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/pre-prints/ct0921rasmussen.

"Treatment of myocardial infarction with bone marrow-derived mesenchymal stem cells (BM-MSCs) and adipose-derived stem cells has shown promising results," said study co-author Dr. Trine Fink. "The transplantation of MSCs in treating myocardial infarction (MI) has been shown to improve left ventricular function in animal models. In this study, we compared the effects of adipose-derived stem cells and BMSCs from an elderly male suffering from coronary atherosclerosis when the donated cells were transplanted randomly, without the administration of immunosuppressant drugs, into two groups of adult rats modeled with MI."

The researchers noted that the age and health status of cell donors are important factors and that the impact of cell transplantation using cells from elderly patients with cardiac ischemia "needs to be elucidated."

The researchers found that ASCs ameliorated heart failure following MI in the group receiving ASCs while the group receiving the BMSCs received no similar benefit. They found that the BMSCs secreted a significantly larger amount of vascular endothelial growth factor, VEGF, than the ASCs, but that did not result
'/>"/>

Contact: Robert Miranda
cogcomm@aol.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

Page: 1 2

Related biology news :

1. Hastings Center resources chart progress in debate over medical research with animals
2. Nitrogen from pollution, natural sources causes growth of toxic algae, study finds
3. Marginal lands are prime fuel source for alternative energy
4. Elsevier launches new journal: Journal of Unconventional Oil and Gas Resources
5. The first genome sequence of Chinese plum provides important resource for fruit improvement
6. Soybeans a source of valuable chemical
7. Lyncean Technologies Inc. sells Compact Light Source to Munich biomedical-imaging research center
8. New test adds to scientists understanding of Earths history, resources
9. Stanford geoscientist cites critical need for basic research to unleash promising energy sources
10. Study IDs kerosene lamps as big source of black carbon
11. Water resources management and policy in a changing world: Where do we go from here?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2015)... Research and Markets( ... "Body-Worn Temperature Sensors Market - Global Industry ... - 2020" report to their offering. ... global body-worn temperature sensors market. The global body-worn ... basis of types, care setting, patient demographic, applications ...
(Date:6/17/2015)... und GERMANTOWN, Maryland , June 17, ... ®   Produktlinie mit DNA-Tests verbessert den Analyseprozess ... QGEN ; Frankfurt Prime Standard: QIA) hat heute ... der Produktlinie Investigator ® ... eingeführt. Die neuen Kits zur Erstellung genetischer Fingerabdrücke bieten ...
(Date:6/16/2015)...  With the increasing number and severity of data ... The recent compromise of Federal employee data from ... within government agencies. HYPR Corp. announced today ... authenticator, has been submitted for testing and approval of ... for tamper proofing. The proliferation of ...
Breaking Biology News(10 mins):Body-Worn Temperature Sensors Market - Global Industry Analysis 2QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 2QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 3QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 4QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 5QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 6Government Ready Biometric Security Approaching as HYPR Corp. Files FIPS 140-2 Level 3 Validation for Its Proprietary Biometric Token 2Government Ready Biometric Security Approaching as HYPR Corp. Files FIPS 140-2 Level 3 Validation for Its Proprietary Biometric Token 3
... tuatara, evolutionary biologist, and ancient DNA expert, Professor David Lambert ... Ecology and Evolution recovered DNA sequences from the bones of ... found that, although tuatara have remained largely physically unchanged over ... a DNA level - faster than any other animal yet ...
... can be found in dye-sensitised solar cells. This type of ... for instance, plants and light-sensitive bacteria. Annemarie Huijser has succeeded ... cell, which is similar to Grtzel cells. Huijser will receive ... 25 March. The use of solar cells is increasing ...
... most cases of cervical cancer has a serious weakness which ... Human Papillomavirus (HPV), a virus which causes several types ... has developed clever ways of hiding in the body, but ... ability to trick the bodys first line of defence leaves ...
Cached Biology News:Tuatara, the fastest evolving animal 2Substantial improvement in essential cheap solar cell process 2Subterfuge, counter-surveillance and assassination: The body's fight with cervical cancer 2
(Date:7/1/2015)... Mesa, CA (PRWEB) , ... July 01, 2015 , ... ... traumatic brain injury (TBI) using single photon emission computed tomography (SPECT) according ... The study, which examined over 20,000 brain scans and is believed to be ...
(Date:7/1/2015)... , July 1, 2015   Neuraltus Pharmaceuticals, ... development of groundbreaking drugs to treat neurodegenerative diseases ... that Robert G. Miller , M.D., Director of ... Health,s California Pacific Medical Center in San Francisco, has ... for $1.5 million to help fund a Phase ...
(Date:7/1/2015)... Indianapolis, IN (PRWEB) , ... July 01, 2015 , ... ... the 2015 BIO International Convention in Philadelphia, PA. , The presentation took ... milestones and outlined the plans for the development of APX3330 for the treatment of ...
(Date:6/30/2015)... 30, 2015 /PRNewswire/ - Resverlogix Corp. ("Resverlogix") (TSX:RVX) ... of Resverlogix have approved the resolutions relating to: ... of 5,600,000 units at a price of $2.67 ... being comprised of one common share and 0.075358 ... approximately CAD$15 million; and (ii) the amendment to ...
Breaking Biology Technology:Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 2Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 3Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 4Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 2Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 3Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 4Apex Therapeutics Presented Company Overview at This Year’s BIO International Convention in Philadelphia, PA 2Resverlogix Corp. Shareholders Approve Matters Relating to Licensing and Equity Arrangement 2Resverlogix Corp. Shareholders Approve Matters Relating to Licensing and Equity Arrangement 3
... , , , , , ... Max-Planck-Institute for Marine Microbiology, Celsiusstr.1, 28359 Germany , ... Introduction , ... in coextraction of other soil components, mainly ...
... , , Bodo Eickhoff and Jrgen van der Bosch ... D-23845 Borstel, Germany. , Tel.: +49 4537 188458 Fax: +49 ... , Abstract , ... improving PCR efficiency: the TaqMaster. With this enhancer, an integral , ...
... , , , , Abstract ... an essential method that allows researchers to determine , the presence, ... the organism, tissue or cell of interest. The basic protocol involves the , ... , by amplification of the gene(s) of interest. Due to buffer ...
Cached Biology Technology:The Use of MasterTaq Polymerase for PCR with Humic Material-Contaminated , DNA 2The Use of MasterTaq Polymerase for PCR with Humic Material-Contaminated , DNA 3The Use of MasterTaq Polymerase for PCR with Humic Material-Contaminated , DNA 4The Use of MasterTaq Polymerase for PCR with Humic Material-Contaminated , DNA 5Enhancing PCR* Efficiency with MasterTaq 2Enhancing PCR* Efficiency with MasterTaq 3Enhancing PCR* Efficiency with MasterTaq 4Enhancing PCR* Efficiency with MasterTaq 5cMaster RTplusPCR System for increased sensitivity and product length , in RT-PCR 2cMaster RTplusPCR System for increased sensitivity and product length , in RT-PCR 3cMaster RTplusPCR System for increased sensitivity and product length , in RT-PCR 4cMaster RTplusPCR System for increased sensitivity and product length , in RT-PCR 5cMaster RTplusPCR System for increased sensitivity and product length , in RT-PCR 6
... T4 DNA Ligase catalyzes the formation of ... between double-stranded DNAs with 3' hydroxyl and ... Ligase buffer optimizes ligation which can be ... acids are not substrates for this enzyme. ...
Bovine Renal Artery Smooth Muscle Cells (BRASMC) (>500,000 cells)...
... The Finnpipette BioControl is a ... technology. A complete liquid handling system ... twelve interchangeable tip cone modules. All ... tip cone modules fit one handle. ...
Sulfadimethoxine (CH-2027)...
Biology Products: